• Journal of Korean Society for Atmospheric Environment
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• v.32 no.5
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• pp.457-468
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• 2016

Traffic-related air pollutants and particulates from diesel exhaust cause for increasing respiratory health problem. Recent epidemiologic studies have reported adverse effects of urban air pollution on various aspects of respiratory health. Bus or truck terminal workers have high probability of exposure to diesel exhaust particle than general office worker. This study was designed to evaluate the relationship between pulmonary function of people who working at the high-density area of diesel vehicles and pulmonary function of people who working at general office in Seoul. So, this study explored the effects on people with exposure to diesel traffic or exposure to diesel traffic, through the pulmonary function test (PFT). There were significant difference in Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1 second ($FEV_1$) between high-exposure group and control. High-exposure to diesel particle were increased risk of reduction in pulmonary function in this study. These results provide the necessity additional research that manage people who working at the high-density area of diesel vehicles.

• Clinical and Experimental Pediatrics
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• v.61 no.2
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• pp.59-63
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• 2018

Purpose: Cardiomyopathy is becoming the leading cause of death in patients with Duchenne muscular dystrophy because mechanically assisted lung ventilation and assisted coughing have helped resolve respiratory complications. To clarify cardiopulmonary function, we compared cardiac function between the home ventilator-assisted and non-ventilator-assisted groups. Methods: We retrospectively reviewed patients with Duchenne muscular dystrophy from January 2010 to March 2016 at Gangnam Severance Hospital. Demographic characteristics, pulmonary function, and echocardiography data were investigated. Results: Fifty-four patients with Duchenne muscular dystrophy were divided into 2 groups: home ventilator-assisted and non-ventilator-assisted. The patients in the home ventilator group were older ($16.25{\pm}1.85years$) than those in the nonventilator group ($14.73{\pm}1.36years$) (P=0.001). Height, weight, and body surface area did not differ significantly between groups. The home ventilator group had a lower seated functional vital capacity ($1,038{\pm}620.41mL$) than the nonventilator group ($1,455{\pm}603.2mL$). Mean left ventricular ejection fraction and fractional shortening were greater in the home ventilator group, but the data did not show any statistical difference. The early ventricular filling velocity/late ventricular filling velocity ratio ($1.7{\pm}0.44$) was lower in the home ventilator group than in the nonventilator group ($2.02{\pm}0.62$. The mitral valve annular systolic velocity was higher in the home ventilator group (estimated ${\beta}$, 1.06; standard error, 0.48). Patients with Duchenne muscular dystrophy on a ventilator may have better systolic and diastolic cardiac functions. Conclusion: Noninvasive ventilator assistance can help preserve cardiac function. Therefore, early utilization of noninvasive ventilation or oxygen may positively influence cardiac function in patients with Duchenne muscular dystrophy.

• Journal of Nutrition and Health
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• v.50 no.6
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• pp.585-594
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• 2017

Purpose: Food intake of COPD patients decreases because of appetite loss, depression, and breathing problems while eating, which increase the likelihood of patients becoming malnourished. This study investigated the nutrient intake and dietary quality of people with and without COPD in Korea. Methods: There were 2,160 adults aged 50 and over who participated in the $5{\sim}6^{th}$ Korea National Health and Nutrition Examination Survey. The subjects were divided into the COPD group and non-COPD group according to the rate of forced expiratory volume at 1 second (FEV1) against forced vital capacity (FVC). Consumption of food and nutrients were calculated based on the nutrition examination survey. Statistical analyses were conducted using SPSS 19.0. Results: Among individuals in their 50s, intake of vitamin $B_1$ in the COPD group was significantly less than the NCOPD group, while intake of sodium in the COPD group was significantly greater than the NCOPD group. Among individuals in their 60s, the energy intake of the COPD group was significantly less than that of the NCOPD group. The COPD group showed significantly less intake of vitamin $B_1$ and vitamin C, but greater intake of sodium than the NCOPD group. In the group aged 70 and over, The COPD group had significantly less intake of vitamin $B_1$ than the NCOPD group and showed lower nutrient adequacy ratio values in protein, vitamin $B_1$, vitamin $B_2$, and iron than the NCOPD group. Conclusion: The COPD group consumed less energy and certain nutrients, and their dietary quality was poor compared to the NCOPD group. Thus, more detailed research is required to understand the concrete relationship between COPD and malnutrition.

• The Korean Journal of Physiology
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• v.10 no.2
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• pp.11-16
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• 1976

In hold that the pulmonary functions which is important situation that the national physical power, at firstly, from age 10 to age 29 young men and women 1,540 person for the progress of grew up, and them to by each aged viewing transition for pulmonary functions physical examination record is as following; and to measure normal Person with comparison by each others pulmonary functions was gained as the results of follows. 1) Frequency of Breathing: It was same the male and female age at 10 per minute over or less of 20 times, but, at age 16 to 17 was $15{\sim}16$ times, and had to precensed compare constant value. 2) Vital Capacity: At the grew up Pregress term as the body stature, age 10 to 17 or 18, had to showing rapidly increasing, but the after Probably constant. The comparison value in man and women in progress of growth up was about $200{\sim}300ml$, and after growth of progress are about 1,500ml, add in men was presence more highly value. 3) Tidal Volume: At a9e 10 was 365m1, but, it was continuing increasing, an4 at age 20 is about 500m1, and the different in men and women about $20{\sim}30$ times and had precense highly value at men. 4) Breathing holding time: It was presence same at male and femele 10 to 13, from 35 second to $37{\sim}38$ seconds, and had to Presence a slight increasing, but, may has to final of the growth progrees age at 14, it should be presence rapidly increasing and the after probably presence as same value but, than female at male is high record average value of $7{\sim}8$ seconds.

• Tuberculosis and Respiratory Diseases
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• v.80 no.3
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• pp.304-310
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• 2017

Background: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory conditions, such as metabolic syndrome. Methods: The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. The relationships between the WBC count, lung function, and symptoms score in COPD patients, were determined, using general linear regression analyses. Results: The WBC count was negatively associated with forced vital capacity (FVC, L), FVC (% predicted), forced expiry volume in one second ($FEV_1$, L), and $FEV_1$ (% predicted) in COPD patients. Additionally, the WBC count was independently associated with the quality of life measure, by EQ5D-index score. However, this relationship between WBC count, and disease severity, was not significant in current smokers, because of the confounding effect of smoking, on the WBC count. Conclusion: The WBC count is associated with current smoking status and COPD severity, and a risk factor for poor lung function, and quality of life, especially in non-currently smoking COPD patients. The WBC count can be used, as an easily measurable COPD biomarker.

• Physical Therapy Korea
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• v.24 no.4
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• pp.68-76
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• 2017

Background: Abdominal bracing exercise (ABE) and abdominal hollowing exercise (AHE) improve the lumbar flexibility and pulmonary function in various patients, yet the efficacy of ABE or AHE have not yet been evaluated. Objects: The purpose of this study was to compare the lumbar flexibility and pulmonary function during both ABE and AHE in healthy adults. Methods: The study included 40 healthy adults, who were randomly divided into the experimental group and control group, each with 20 subjects. All subjects performed ABE (experimental group) and AHE (control group). The lumbar flexibility such as trunk flexion test (sitting and standing position) and schober test and pulmonary function such as the spirometer including forced vital capacity (FVC) and force expiratory volume in one second ($FEV_1$) and chest circumference measurement (middle and lower chest) were measured, respectively. Two-way repeated analysis of variance was used to compare the lumbar flexibility and pulmonary function, respectively. Results: No significant effects of lumbar flexibility were observed on trunk flexion test from the sitting position (P=.478) and standing position (P=.096) in the ABE than in the AHE. However, the length of ABE was longer significantly than it of AHE (P=.024). No significant effects of lung function were observed on the FVC (P=.410) and $FEV_1$ (P=.072) in the ABE group than in the AHE group. And also, no significant effects of chest circumference measurement were observed on the inspiration (P=.468) and expiration (P=.563) in middle chest circumference and inspiration (P=.104) and expiration (P=.346) in lower chest circumference. Conclusion: This study indicated that the ABE is only more effective in lumbar flexibility by lumbar length difference than AHE in healthy adults.

• Research in Community and Public Health Nursing
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• v.16 no.2
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• pp.177-185
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• 2005

Purpose: This study was to examine the effects of an exercise program on physical fitness, cardiopulmonary function and life satisfaction for adult women. Method: The exercise program combined dance and resistance training. The subject group consisted of 114 women aged between 33 and 60. Three 8-week sessions consisted of 55-80% HR max for 60-90 minutes a day and 3 times a week from March to November, 2004. Data were collected through pre- and post-exercise tests before and after each session. Data were collected with dynamometer, sphygmomamometer, spirometer and structured questionnaires. Data were analyzed employing descriptive statistics and paired t-test with SPSS/PC(10.0version) program. Results: There were significantly positive changes in muscle strength, flexibility, balance quality, forced vital capacity and life satisfaction, but no significantly positive changes in agility and blood pressure. Conclusion: This study showed that an exercise program has partially positive effects for adult women. The results of this study suggest that there should be programs of continuous exercise at community health centers for adult women's health.

• Journal of Korean Academy of Nursing
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• v.18 no.2
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• pp.105-117
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• 1988

To evaluate training effect, aerobic dance was performed by eight female collegestudents for 8 weeks. Body composition, cardiopulmonary function at rest and during maximal exercise, blood cholesterol concentration at rest were determined before and after 8weeks of aerobic dance training. Maximal exercise was performed on the treadmill according of Bruce protocol. Pre to post training differences were evaluated. The results obtained were as follows : 1. After the training, skinfold thickness and total body fat decreased significantly(p＜0.1) while lean body mass increased with significance (p＜0.1). 2. Heart rate and arterial blood pressure at rest decreased without sinificance after the training. 3. As a result of training, forced vital capacity and forced expiratory volume for a second increased significantly (p＜0.01, p＜0.1). 4. After the training period, heart rate at 3, 6, and 9 min. during treadmill exercise was significantly lower than those of pretraining (p＜0.05). 5. After the training, systolic and diastolic blood pressure at 6 and 9 min during the exercise was significantly lower than those of pretraining (p＜0.025, p＜0.1). 6. After the training, oxygen uptake at 3 and 6 min during the exercise was significantly greater than those of pretraining (p＜0.05). 7. As a result of training, the maximal oxygen uptake increased significantly during the exercise (p＜0.1). 8. After the training, expired air volume for a minute at 3 and 6 min during the exercise was signigicantly grerter than those of pretraining (p＜0.1). 9. After the training, repiratory quotient during the exercise was lower than pretaining without significance. 10. After the training, blood HDL -cholesterol concentration incereased with significance, (p＜0.1) blood total cholesterol and triglycerids concentration decreasedsignificantly (p＜0.1). From these results, it may be concluded that 8 week aerobic dance training reduces skinfold thickness and body fat contents, improves the cardiopulmonary function and tissue oxygen utilization, reduces blood cholesterol and triglyceride concentration and brings about the increase of blood HDL-cholesterol concentriation.

• Preventive Nutrition and Food Science
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• v.16 no.4
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• pp.313-320
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• 2011

The oxidative stress level and antioxidant activities in two green algae (Ulva pertusa and Ulva linza), two brown algae (Agarum cribrosum and Dictyota dichotoma), and three red algae (Grateloupia lanceolata, Carpopeltis affinis, and Gracilaria verrucosa) collected from intertidal regions of Korea were assessed. In the two green algae, although the total glutathione content was not as high as that of the brown algae, the glutathione pool was extremely reduced, and the glutathione reductase (GRd)/glutathione peroxidase (GPx) activity ratio was high, which apparently plays an important role for protection against oxidative damage, as manifested by low lipid peroxidation. In the brown algae, which exhibited a low lipid peroxidation level that was comparable to the green algal species, the highest glutathione content, together with high GPx activity, appears to be the most important factor in their antioxidant protection. The red algal species exhibited extremely high lipid peroxidation levels. They also contained the lowest and most oxidized glutathione among the species, as well as the lowest GRd activity. In spite of the marked difference in the glutathione content, the significant difference in the activity of ${\gamma}$-glutamylcysteine ligase, the rate limiting enzyme for glutathione synthesis, among the species was not exhibited. Our results suggest that there is a significant difference in the levels of oxidative stress and antioxidant capacity among the algal species, and that the glutathione system, especially the efficiency of glutathione recycling, plays a vital role in antioxidative protection in algal species.

• Clinical and Experimental Pediatrics
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• v.58 no.6
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• pp.218-223
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• 2015

Purpose: Idiopathic scoliosis is a structural lateral curvature of the spine of unknown etiology. The relationship between degree of spine curvature and cardiopulmonary function has not yet been investigated. The purpose of this study was to determine the association between scoliosis and cardiopulmonary characteristics. Methods: Ninety children who underwent preoperative pulmonary or cardiac evaluation at a single spine institution over 41 months were included. They were divided into the thoracic-dominant scoliosis (group A, n=78) and lumbar-dominant scoliosis (group B, n=12) groups. Scoliosis severity was evaluated using the Cobb method. In each group, relationships between Cobb angles and cardiopulmonary markers such as forced vital capacity (FVC), forced expiratory volume in one second ($FEV_1$), $FEV_1$/FVC, left ventricular ejection fraction, pulmonary artery flow velocity, and tissue Doppler velocities (E/E', E'/A') were analyzed by correlation analysis linear regression. Results: In group A, 72 patients (92.3%) underwent pulmonary function tests (PFTs), and 41 (52.6%) underwent echocardiography. In group B, 9 patients (75.0%) underwent PFT and 8 (66.7%) underwent echocardiography. Cobb angles showed a significant negative correlation with FVC and $FEV_1$ in group A (both P<0.05), but no such correlation in group B, and a significant negative correlation with mitral E/A ratio (P<0.05) and tissue Doppler E'/A' (P<0.05) in group A, with a positive correlation with mitral E/A ratio (P<0.05) in group B. Conclusion: Pulmonary and cardiac function was significantly correlated with the degree of scoliosis in patients with thoracic-dominant scoliosis. Myocardial diastolic function might be impaired in patients with the most severe scoliosis.