• Title/Summary/Keyword: Vital Signal

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The Transmission of Tele-Information System using BlueTooth (블루투스를 이용한 웹으로의 원격 의료정보 전송 시스템)

  • 채희영;강형원;김영길
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2002.05a
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    • pp.130-133
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    • 2002
  • As a society advances, an aging phenomenon and many diseases which did not exist in old times are happening. Especially, in case of the aged patient, because we cant know the time the condition of the patients health become worse, the study of the Tele-information system has been actively carried out by the necessity of a persistent observation. A ECG signal a kind of a vital signals has been widely used to the medical information system as an usual clinical diagnosis for the patients who possess heart diseases. BlueTooth is a close range wireless communication technology which uses a wireless frequency 2.4GHz and has a high trust and self - error correction technology according to a low power consumption quality and a high-speed frequency hopping. This makes get a high trust concerning a data transmission than an existing modem. In addition, though wireless modem is restricted by a minimal of a wireless terminal, It will be possible to coincide with the function of the portable with the low power consumption quality by using Bluetooth. And as the system on a chip of module progresses, the possibility of the small size is present According to this, Bluetooth module transmits the medical information, which is input from the outside among the operations that use the Bluetooth to the Bluetooth module that is connected the host PC. And the system that the host PC transmits the medical information from the connected Bluetooth module to the Internet has once embedded. this study let the host PC embedded in advance of the existing system and transmit the medical information by the addition of the Tcp/Ip protocol stark under all embedded environments to internet.

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Notoginseng leaf triterpenes ameliorates mitochondrial oxidative injury via the NAMPT-SIRT1/2/3 signaling pathways in cerebral ischemic model rats

  • Weijie, Xie;Ting, Zhu;Ping, Zhou;Huibo, Xu;Xiangbao, Meng;Tao, Ding;Fengwei, Nan;Guibo, Sun;Xiaobo, Sun
    • Journal of Ginseng Research
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    • v.47 no.2
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    • pp.199-209
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    • 2023
  • Background: Due to the interrupted blood supply in cerebral ischemic stroke (CIS), ischemic and hypoxia results in neuronal depolarization, insufficient NAD+, excessive levels of ROS, mitochondrial damages, and energy metabolism disorders, which triggers the ischemic cascades. Currently, improvement of mitochondrial functions and energy metabolism is as a vital therapeutic target and clinical strategy. Hence, it is greatly crucial to look for neuroprotective natural agents with mitochondria protection actions and explore the mediated targets for treating CIS. In the previous study, notoginseng leaf triterpenes (PNGL) from Panax notoginseng stems and leaves was demonstrated to have neuroprotective effects against cerebral ischemia/reperfusion injury. However, the potential mechanisms have been not completely elaborate. Methods: The model of middle cerebral artery occlusion and reperfusion (MCAO/R) was adopted to verify the neuroprotective effects and potential pharmacology mechanisms of PNGL in vivo. Antioxidant markers were evaluated by kit detection. Mitochondrial function was evaluated by ATP content measurement, ATPase, NAD and NADH kits. And the transmission electron microscopy (TEM) and pathological staining (H&E and Nissl) were used to detect cerebral morphological changes and mitochondrial structural damages. Western blotting, ELISA and immunofluorescence assay were utilized to explore the mitochondrial protection effects and its related mechanisms in vivo. Results: In vivo, treatment with PNGL markedly reduced excessive oxidative stress, inhibited mitochondrial injury, alleviated energy metabolism dysfunction, decreased neuronal loss and apoptosis, and thus notedly raised neuronal survival under ischemia and hypoxia. Meanwhile, PNGL significantly increased the expression of nicotinamide phosphoribosyltransferase (NAMPT) in the ischemic regions, and regulated its related downstream SIRT1/2/3-MnSOD/PGC-1α pathways. Conclusion: The study finds that the mitochondrial protective effects of PNGL are associated with the NAMPT-SIRT1/2/3-MnSOD/PGC-1α signal pathways. PNGL, as a novel candidate drug, has great application prospects for preventing and treating ischemic stroke.

Analysis of Uncertainty in Ocean Color Products by Water Vapor Vertical Profile (수증기 연직 분포에 의한 GOCI-II 해색 산출물 오차 분석)

  • Kyeong-Sang Lee;Sujung Bae;Eunkyung Lee;Jae-Hyun Ahn
    • Korean Journal of Remote Sensing
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    • v.39 no.6_2
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    • pp.1591-1604
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    • 2023
  • In ocean color remote sensing, atmospheric correction is a vital process for ensuring the accuracy and reliability of ocean color products. Furthermore, in recent years, the remote sensing community has intensified its requirements for understanding errors in satellite data. Accordingly, research is currently addressing errors in remote sensing reflectance (Rrs) resulting from inaccuracies in meteorological variables (total ozone, pressure, wind field, and total precipitable water) used as auxiliary data for atmospheric correction. However, there has been no investigation into the error in Rrs caused by the variability of the water vapor profile, despite it being a recognized error source. In this study, we used the Second Simulation of a Satellite Signal Vector version 2.1 simulation to compute errors in water vapor transmittance arising from variations in the water vapor profile within the GOCI-II observation area. Subsequently, we conducted an analysis of the associated errors in ocean color products. The observed water vapor profile not only exhibited a complex shape but also showed significant variations near the surface, leading to differences of up to 0.007 compared to the US standard 62 water vapor profile used in the GOCI-II atmospheric correction. The resulting variation in water vapor transmittance led to a difference in aerosol reflectance estimation, consequently introducing errors in Rrs across all GOCI-II bands. However, the error of Rrs in the 412-555 nm due to the difference in the water vapor profile band was found to be below 2%, which is lower than the required accuracy. Also, similar errors were shown in other ocean color products such as chlorophyll-a concentration, colored dissolved organic matter, and total suspended matter concentration. The results of this study indicate that the variability in water vapor profiles has minimal impact on the accuracy of atmospheric correction and ocean color products. Therefore, improving the accuracy of the input data related to the water vapor column concentration is even more critical for enhancing the accuracy of ocean color products in terms of water vapor absorption correction.