• Title/Summary/Keyword: Visual Organs

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Thirteen Weeks Repeated-dose Toxicity Study on Aconitum ciliare Decaisne Pharmacopuncture Solution in Mice (초오 약침액의 13주 반복 시술 독성에 관한 연구)

  • Lim, Sung Chul;Kim, Jae Soo;Lee, Bong Hyo;Lee, Hyun Jong;Lee, Hyun;Lee, Yun Kyu
    • Korean Journal of Acupuncture
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    • v.35 no.3
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    • pp.139-148
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    • 2018
  • Objectives : This study was performed to examine the toxicity on the long term procedure of Aconitum ciliare Decaisne pharmacopuncture(ADP) solution. Methods : To evaluate the long term toxicity of 3 different repeated doses, 60, 150, and 300 mg/kg/day for 13 weeks were injected into BALB/c mice, respectively. The ADP solution was injected into near ST36 of the right leg and normal saline of the same volume was used for the vehicle control group. To evaluate the toxicity of 60, 150, and 300 mg/kg of repeated doses for 13 weeks, toxic symptoms, weight measurement, hematological test, blood biochemical test, visual examination and weight measurement of major organs, and histopathological test were conducted. Results : No significant changes in toxic symptoms, weight measurement, hematological test, blood biochemical test, visual examination and weight measurement of major organs, and histopathological test were observed in different doses of ADP solution treated groups compared to vehicle control group. Conclusions : As a result, repeated dose at a concentration of 300 mg/kg or less is considered to be not harmful for clinical treatment.

Feeding Ecology of Black Rockfish, Sebastes inermis (볼락, Sebastes inermis 의 섭식상태)

  • KIM Chong-Kwan;KANG Yong-Joo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.5
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    • pp.637-641
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    • 1999
  • This study was carried out to understand feeding ecology of black rockfish, Sebastes inermis in the coastal waters off Shinsudo, Sachon. The specimens were collected by angling, gill net, small danish seine, and long-bag net from February 1984 to May 1985. The fish consisted of 5 age groups from 0 to 4. Feeding activity was more intensive in the early morning and late afternoon in spring and summer, but the fish showed intermittent feeding activities in autumn and winter. Although the food items of the fish changed slightly by seasons and with growth of the fish, main food items were cope pods, gammarids, caprellids, carideans, polychaetes, and brachyurans. Of these food items, cope pods were major preys for the fish of age group 0, and gammarids over age group 1. Evenness and diversity of the food items increased as the fish grew. In consideration of feeding organs, digestive organs and stomach contents of the fish, S. inermis seemed to be not only carnivore but also visual feeder consuming mainly small crustaceans.

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Deleuze's Deterritorialization Body without Organs in Contemporary Fashion -Focusing on Central Saint Martins, Royal College of Art, Antwerp Royal Academy of Fine Arts Graduation works- (현대 패션에 표현된 들뢰즈의 탈영토화와 기관 없는 신체 -영국 센트럴 세인트 마틴스 예술대학, 영국 왕립예술대학교, 벨기에 앤트워프 왕립예술대학의 2017-2019 줄업 작품을 중심으로-)

  • Wang, Xin-yu;Kim, Hyun-Joo
    • Journal of Digital Convergence
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    • v.18 no.12
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    • pp.549-563
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    • 2020
  • Based on Deleuze's body aesthetics and from the perspective of 'deterritoraliazation', this study makes an in-depth discussion on the modern fashion design modeling by four visual characteristics: hysteria, visualization, body segmentation and becoming animals. First, hysteria embodies the strong visual effect brought by the deformation and exaggeration of clothing. Second, visualization in fashion shows the elimination or ambiguity of faces, representing the weakening of identity and the prominence of clothing and body. Third, body segmentation represents the deconstruction and reorganization of clothing, and a new way of thinking, as well. Fourth, becoming-animals are manifested in the physical mutation caused by the heterogeneous connection between humans and animals, which brings about the possibility of rethinking the body.

An Experimental Study on Single-dose and 4 Weeks Repeated-dose Toxicity of Aconitum ciliare Decaisne Pharmacopuncture (초오약침의 단회 및 4주 반복 투여 독성에 관한 실험적 연구)

  • Lee, Hyun Su;Lee, Yun Kyu;Lee, Bong Hyo;Kim, Jae Soo;Lim, Sung Chul;Lee, Hyun-Jong
    • Korean Journal of Acupuncture
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    • v.34 no.4
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    • pp.241-250
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    • 2017
  • Objectives : This study was performed to examine the toxicity of Aconitum ciliare Decaisne pharmacopuncture(ADP). Methods : The toxicity was evaluated for lethal dose for 50 percent kill(LD50), single dose and repeated dose for 4 weeks. Toxic symptoms, weight measurement, hematological test, blood biochemical test, visual examination and weight measurement of major organs and histopathological test were observed for 4 weeks. Dose of 300, 600, 1,200, 2,400, 3,600, 4,800, 6,000, 7,200 mg/kg in the LD50 experiment, 300, 600, 1,200 mg/kg/day in the single experiment, 150, 300, 600 mg/kg/day in 4 weeks experiments were injected into BALB/c mice. The ADP was injected into ST36 of the right leg. Normal saline solution of same volume was used for control group. In 24 hours after the last treatment, blood samples were taken after anesthesia by inhalation of ethyl ether. After that, the BALB/c mice were euthanized. Their heart, lungs, kidneys, liver and reproductive organs were removed and weighed. Histopathological evaluation was also performed. Results : ADP's LD50 was measured at 6,000 mg/kg. In both single and repeated dose toxicity test, no BALB/c mouse died during the experiments. ADP treatment for 4 weeks did not show any significant changes in toxic symptoms, weight measurement, hematological test, blood biochemical test, visual examination and weight measurement of major organs and histopathological test. Conclusions : As a result, ADP's LD50 was 6,000 mg/kg and repeated dose at a concentration of 600 mg/kg or less is considered to be not harmful for clinical treatment.

Example Development of Medical Equipment Applying Power Electronics Technique (전력전자 기술을 응용한 의료장비 개발 사례)

  • 고종선;이태훈;김영일;김규겸;박병림
    • The Transactions of the Korean Institute of Power Electronics
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    • v.7 no.6
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    • pp.524-530
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    • 2002
  • A control of the body posture and movement is maintained by the vestibular system, vision, and proprioceptors. Afferent signals from those receptors are transmitted to the vestibular nuclear complex, and the efferent signals from the vestibular nuclear complex control the eye movement and skeletal muscle contract. The postural disturbance caused by loss of the vestibular function results in nausea, vomiting, vertigo and loss of craving for life. The purpose of this study is to develop a off-vertical rotatory system for evaluating the function of semicircular canals and otolith organs, selectively, and visual stimulation system for- stimulation with horizontal, vortical and 3D patterns. The Off-vortical axis rotator is composed of a comportable chair, a DC servo-motor with reducer and a tilting table controlled by PMSM. And a double feedback loop system containing a velocity feedback loop and a position feedback loop is applied to the servo controlled rotatory chair system. Horizontal, vertical, and 3D patterns of the visual stimulation for applying head mounted display are developed. And wireless portable systems for optokinetic stimulation and recording system of the eye movement is also constructed. The gain, phase, and symmetry is obtained from analysis of the eye movement induced by vestibular and visual stimulation. Detailed data were described.

A Study on Furniture Design using the Five Senses -Focusing on Synesthesia in Design- (오감(五感)을 이용한 가구디자인에 관한 연구 - 디자인에서의 공감각(共感覺)을 중심으로 -)

  • Yoon, Yeoh-Hang;Yoo, Do-Hyun
    • Journal of the Korea Furniture Society
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    • v.21 no.2
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    • pp.133-143
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    • 2010
  • Although past design developments that emphasized only the outer appearances of products were mostly concentrated on the areas of forms and colors in an attempt to satisfy humans' visual needs, it is expected that future designs to come will go in the direction to stimulate more diversified human senses. This means expansions to the five senses including the auditory sense, the sense of smell, the tactile sense and the taste and even to the area of synesthesia where two or more senses are stimulated or coexist. Although the dictionary definition of synesthesia is a concept of arousing another sense through a sense, studies of synesthesia in design go one step further from here to mean compound senses, that is, the synesthesia in an expanded meaning to feel an object (thing) through many sensory organs simultaneously. The synesthesia in the expanded meaning is applying multiple senses simultaneously in recognizing one thing to comprehensively judge and feel the thing. Recent design trends are going in a direction to basically satisfy humans' visual needs through controlled forms and colors while inducing another new feeling through expressions of diverse feels of materials within existing forms. In this change of the times, studies on furniture designs are conducted through factors of in synesthesia linked with other senses and have an important meaning that can enhance the value of designs.

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Effect of Visual and Somatosensory Information Inputs on Postural Sway in Patients With Stroke Using Tri-Axial Accelerometer Measurement

  • Chung, Jae-yeop
    • Physical Therapy Korea
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    • v.23 no.1
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    • pp.87-93
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    • 2016
  • Background: Posture balance control is the ability to maintain the body's center of gravity in the minimal postural sway state on a supportive surface. This ability is obtained through a complicated process of sensing the movements of the human body through sensory organs and then integrating the information into the central nervous system and reacting to the musculoskeletal system and the support action of the musculoskeletal system. Motor function, including coordination, motor, and vision, vestibular sense, and sensory function, including proprioception, should act in an integrated way. However, more than half of stroke patients have motor, sensory, cognitive, and emotional disorders for a long time. Motor and sensory disorders cause the greatest difficulty in postural control among stroke patients. Objects: The purpose of this study is to determine the effect of visual and somatosensory information on postural sway in stroke patients and carrying out a kinematic analysis using a tri-axial accelerometer and a quantitative assessment. Methods: Thirty-four subjects posed four stance condition was accepted various sensory information for counterbalance. This experiment referred to the computerized dynamic posturography assessments and was redesigned four condition blocking visual and somatosensory information. To measure the postural sway of the subjects' trunk, a wireless tri-axial accelerometer was used by signal vector magnitude value. Ony-way measure analysis of variance was performed among four condition. Results: There were significant differences when somatosensory information input blocked (p<.05). Conclusion: The sensory significantly affecting the balance ability of stroke patients is somatosensory, and the amount of actual movement of the trunk could be objectively compared and analyzed through quantitative figures using a tri-axial accelerometer for balance ability.

Development of the off-vertical rotatory chair and visual stimulation system for evaluation of the vestibular function (전정기능 평가를 위한 탈수직축 회전자극 시스템 및 HMD 시스템의 개발)

  • 김규겸;고종선;박병림;김인동
    • The Transactions of the Korean Institute of Power Electronics
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    • v.6 no.4
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    • pp.325-332
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    • 2001
  • The vestibular system located in the inner ear controls reflex body posture and movement, It has the semicircular canals sensing an angular acceleration and the otolith organs sensing a linear acceleration. With this organic signal, medical doctor decide if a person has disease or not. To obtain this data, a precision stimular system is considered. Robust control is needed to obtain eye signals induced by off-vertical axis rotation because of an unbalanced load produced by tilting the axis of the system upto 30 degrees. In this study, off-vertical axis rotatory system with visual stimulation system are developed. This system is consisted of head mounted display for generating horizontal, vertical, and three dimensional stimulus patterns. Furthermore wireless recording system using RF modem is considered for noiseless data transmission. Detailed data was described.

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Effects of Multimodal Stimuli on Human Sensibility (시청각 복합자극에 대한 인감감성의 변화)

  • 이구형;김병주;정일석
    • Science of Emotion and Sensibility
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    • v.4 no.1
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    • pp.43-51
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    • 2001
  • When consumer evaluates a product, every aspec of the product affects the evaluation. Human uses at least five sensory organs for the evaluation. Multi-sensory or multi-modal design tries to add auditory and olfactory factors to the traditional visual-centered design. For the multi-modal design, it is essential to understand relationships between combined sensory stimuli and human sensibility. Information between simple sensory stimulus and human sensibility is pre-requisite to combine multi-modal stimuli. This study investigated human sensibility against 8 colors and 30 sounds, presented independently. The combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli was investigated with 20 female subjects. For combined stimuli that generated the same kind of sensibility respectively, generated sensibility was same but strength was diminished. For combined stimuli that generated the different sensibilities respectively, subjects showed neutral sensibility or no special sensibilities. Sensibilities to the same stimuli also showed difference depending on personal background of the subjects.

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Research Trends and Challenges in Technology Development of Medical Electronic Implant Devices (이식형 전자의료기 연구동향과 기술개발의 과제)

  • Cho, Jin-Ho
    • Journal of Biomedical Engineering Research
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    • v.29 no.6
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    • pp.415-430
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    • 2008
  • The technologies in medical electronic implant(MEI) devices are developing rapidly, and already, there are various kinds of the MEI devices in the current medical equipments market. Recently, the global market scale of MEI devices have been increased about 13% year by year, and the import amount of MEI devices in Korea is increasing rapidly. In the near future, the demands of MEI devices will be magnificently increasing by the continuous development of the biomedical electronics devices which coupled with neural, brain and other organs will bring us to tremendous effects, such as providing new therapeutic solutions to patients, extension and saving human life, and an important clue of medical development. However, the investment of the research and the activity of developments in this field are still very weak in the Korea. Consequently, this paper introduces about the research trends of MEI devices, and technological problems those must be solved, and then concludes with the suggestions in order to be the leading country in this field.