• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.273-275
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• 2022

The use of drugs by pregnant women poses a potential risk to the fetus. Therefore, it is essential to classify drugs that pregnant women should prohibit. However, the fetal toxicity of most drugs has not been identified. This takes a lot of time and cost. In silico approaches, such as virtual screening, can identify compounds that may present a high risk to the fetus for a wide range of compounds at the low cost and time. We collected class information of each drug from the hazard classification lists for prescribing drugs in pregnancy by the government of Korea and Australia. Using the structural and chemical features of each drug, various machine learning models were constructed to predict fetal toxicity of drugs. For all models, the quantitative performance evaluation was performed. Based on the attention algorithm, important molecular substructures of compounds were identified in the process of predicting the fetal toxicity of the drug by the proposed model. From the results, we confirmed that drugs with a high risk of fetal toxicity can be predicted for a wide range of compounds by machine learning. This study can be used as a pre-screening tool for fetal toxicity predictions, as it provides key molecular substructures associated with the fetal toxicity of compounds.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.1
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• pp.159-166
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• 2004

Custom-tailored products are meant by the products having various sizes and shapes to meet the customer's different tastes or needs. Thus fabrication of custom-tailored products inherently involves inefficiency. To minimize this inefficiency, a new paradigm is proposed in this work. In this paradigm, different parts are grouped together according to their sizes and shapes. Then, representative shape of each group is derived and it will be used as the work-piece from which the parts in the group are machined. Once a new product is ordered, the optimal work-piece is selected through making similarity comparisons of new product and each representative shape. Then an effective NC tool-path is generated to machine only the different portions between the work-piece and the ordered product. The efficient machining conditions are also derived from this shape difference. By machining only the different portions between the work-piece and the ordered product, it saves time. Similarity comparison starts with the determination of the closest pose between two shapes in consideration. The closest pose is derived by comparing the ray distances while one shape is virtually rotated with respect to the other. Shape similarity value and overall similarity value calculated from ray distances are used for grouping. A prototype system based on the proposed methodology has been implemented and applied to the grouping and machining of the shoe lasts of various shapes and sizes.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.70-73
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• 2003

Custom-tailored products are meant by the products having various sizes and shapes to meet the customer's different tastes or needs. Thus fabrication of custom-tailored products inherently involves inefficiency. To minimize this inefficiency, a new paradigm is proposed in this work. In this paradigm. different paris are grouped together according to their sizes and shapes. Then, representative shape of each group is derived and it will be used as the work-piece from which the parts in the group are machined. Once a new product is ordered, the optimal work-piece is selected through making similarity comparisons of new product and each representative shape. Then an effective NC tool-path is generated to machine only the different portions between the work-piece and the ordered product. The efficient machining conditions are also derived from this shape difference. By machining only the different portions between the work-piece and the ordered product, it saves time. Similarity comparison starts with the determination of the closest pose between two shapes in consideration. The closest pose is derived by comparing the ray distances while one shape is virtually rotated with respect to the other. Shape similarity value and overall similarity value calculated from ray distances are used for grouping. A prototype system based on the proposed methodology has been implemented and applied to the grouping and machining of the shoe lasts of various shapes and sizes.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.11 no.6
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• pp.1-9
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• 2002

This study describes the geometric characteristics and the 5-axis machining method in order to make end mill cutter coming with insert tips. End mill geometry is consisted of flute part and insert tip part. Flute part modeled by using ruled surfaces with constant helix angle, and insert tip part modeled by rectangular planes containing tapped hole of specified direction in its center. In this study, the modeled insert tip part considered both of a radial rake angle and a axial rake angle, because they were important cutting conditions. In order to machining the virtual end mill defined from geometric characteristics, we programmed a special software to machining the end mill considered in this study. This software can generate NC-codes about following processes, end milling or ball end milling of flute part end milling of rectangular plane, centering of hole, drilling of hole, and tapping of hole. Ant sampled end mills were modeled and machined on 5-axis CNC machining center with two index tables. Since machined end mills were very agreeable to designed end mills, we saw that the method proposed in this study can be very useful for manufacturing of end mill body with insert tip.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.407-413
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• 2023

The purpose of this study is to provide basic information about various methods to easily affix unique embroidery effects to clothes due to the current expansion of digital fashion technology. A comparison of design techniques using virtual and real clothing was used to show the visual expression of embroidery designs. Actual embroidery motifs were created using a computer embroidery machine, DTP embroidery motifs were made by utilizing digitalization techniques, and digital motifs were produced. Then patch pocket type T-shirts were produced using each embroidery technique to compare the visual expression effects on clothing. The results of this comparison are as follows: for real clothing color (3.5), texture (4.0), gloss (3.8), and thickness (3.5). It was found that the color and thickness of the embroidery floss was visually sufficiently show the design texture and gloss. In terms of the embroidery design on virtual garments, the resutls of color (3.8), texture (4.3), gloss (3.9), and thickness (3.6) showed a high degree of similarity to the non-virtual results, confirming that digitized embroidery motifs are also a tool that can fully realize unique embroidery effect.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.2
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• pp.305-311
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• 2010

iATA (Internet Advanced Technology Attachment) is a block-level protocol developed to transfer ATA commands over TCP/IP network, as an alternative network storage solution to address insufficient storage problem in mobile devices. This paper employs RAID5 distributed storage servers concept into iATA, in which the idea behind is to combine several machines with relatively inexpensive disk drives into a server array that works as a single virtual storage device, thus increasing the reliability and speed of operations. In the case of one machine failed, the server array will not destroy immediately but able to function in a degradation mode. Meanwhile, information can be easily recovered by using boolean exclusive OR (XOR) logical function with the bit information on the remaining machines. We perform I/O measurement and benchmark tool result indicates that additional fault tolerance feature does not delay read/write operations with reasonable file size ranged in 4KB-2MB, yet higher data integrity objective is achieved.