• Journal of Chest Surgery
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• v.40 no.8
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• pp.546-551
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• 2007

Background: The radial artery is gaining widespread acceptance as complementary arterial conduits for surgical myocardial revascularization, but there have been limited reports about its angiographic patency compared with that of internal thoracic artery or saphenous vein. We tried to evaluate angiographic patency of radial artery graft and to compare that of radial artery and other gratis with retrospective manner. Material and Method: From January 2001 to Jure 2006, totally 132 patients (male 92, female 40) who underwent coronary artery bypass graft using radial artery were re-admitted to our hospital for follow up angiographic examination. Mean age was 58.2+8.87 and mean follow up duration was 32 month ($2{\sim}110$ month). Off pump and on pump bypass surgery were performed 74 and 58 patients respectively. Along with radial artery, left internal thoracic arteries were used in 57 cases, concomitant left internal thoracic artery and saphenous veins were used in 47 cases and bilateral internal thoracic arteries were used in 20 cases. Result: Totally 412 distal anastomosis were performed and 376 anastomosis remained patent (91.2%). Left internal thoracic artery showed the most excellent patency in all of the conduits (98.5%). Radial artery graft patency was 90.8% (169/186). There was no statistical difference of the patency by conduit between on-pump and off-pump group. But radial artery showed more higher patency rate (98/110, 89%) in the severe stenotic lesion that preoperatively revealed more than 90% stenosis than in the lesser severe (<90%) stenotic lesion (60/76, 78%)(p < 0.005). Radial artery conduit represented the worst result when it was grafted in the right coronary system. But when it was positioned in the left heart especially diagonal or obtuse marginal area, patency was comparable with left internal thoracic artery. Conclusion: Radial artery graft showed good midterm patency when it was used in the severe stenotic lesion more than 90% and left coronary system. But great notice should be taken when it is grafted in the right coronary system or less severe stenotic lesion.

• Journal of Chest Surgery
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• v.41 no.2
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• pp.149-159
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• 2008

Background: With increasing coronary bypass and peripheral vascular surgeries, the demand for homologous vascular or synthetic conduits has continued to grow, but wide-spread application has been limited by dismal patency rates. Although cryopreserved allograft valves may provide a suitable alternative, current viability or patency of implanted allograft vascular conduits has been unsatisfactory. Material and Method: We serially analyzed the outcomes of canine femoral artery and saphenous vein allograft implants after storage in either $4^{\circ}C\;or\;-170^{\circ}C$. Result: There were no differences in graft flow rate (patency) (p=0.264), rate of thrombosis (p=0.264), presence of endothelium (p=0.587), or immunohistochemical staining for thrombomodulin (p=0.657) were detected between grafts stored in $4^{\circ}C\;and\;-170^{\circ}C$. Greater flow occurred in the arterial grafts versus the venous grafts (p=0.030), irrespective of the preservation method, with a significantly lower incidence of thrombosis (p=0.030) in arterial allografts. There was a correlation coefficient of -0.654 between thrombosis and positive immunohistochemical staining for thrombomodulin (p=0.006) and a correlation coefficient of 0.520 (p=0.0049) between the endothelial presence and positive immunohistochemical staining for thrombomodulin. The relationship between the presence of endothelium and thrombomodulin expression failed to show any correlation within the first 2 weeks (p=0.306). However, a strong correlation was seen after 1 month (p=0.0008). Conclusion: Tissue storage in either $4^{\circ}C\;or\;-170^{\circ}C$ in 10% DMSO/RPMI-1640 preservation solution preserved grafts equally well. In terms of thrombosis and graft patency, arterial grafts were superior to venous grafts. Considering the poor correlation between thrombomodulin expression and the presence of an endothelium in the implanted graft within the first two weeks, grafts in this period would not be thromboresistant.

• Journal of the Mineralogical Society of Korea
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• v.26 no.3
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• pp.161-174
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• 2013

The geology of the weondong deposit area consists mainly of Cambro-Ordovician and Carboniferous-Triassic formations, and intruded quartz porphyry and dyke. The skarn mineralized zone in the weondong deposit is the most prospective region for the useful W-mineral deposits. To determine the skarn-mineralization age, U-Pb SHRIMP and K-Ar age dating methods were employed. The U-Pb zircon ages of quartz porphyry intrusion (WD-A) and feldspar porphyry dyke (WD-B) are 79.37 Ma and 50.64 Ma. The K-Ar ages of coarse-grained crystalline phlogopite (WD-1), massive phlogopite (WDR-1), phlogopite coexisted with skarn minerals (WD-M), and vein type illite (WD-2) were determined as $49.1{\pm}1.1$ Ma, $49.2{\pm}1.2$ Ma, $49.9{\pm}3.6$ Ma, and $48.3{\pm}1.1$ Ma, respectively. And the ages of the high uranium zircon of hydrothermally altered quartz porphyry (WD-C) range from 59.7 to 38.7 Ma, which dependson zircon's textures affected by hydrothermal fluids. It is regarded as the effect of some hydrothermal events, which may precipitate and overgrow the high-U zircons, and happen the zircon's metamictization and dissolution-reprecipitation reactions. Based on the K-Ar age datings for the skarn minerals and field evidences, we suggest that the timing of W-skarn mineralization in weondong deposit may be about 50 Ma. However, for the accurate timing of skarn mineralization in this area, the additional researches about the sequence of superposition at the skarn minerals and geological relationship between skarn deposits and dyke should be needed in the future.

• Korean Journal of Microbiology
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• v.45 no.3
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• pp.251-256
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• 2009

Leaf samples and bulbs showing characteristic symptoms of virus infection were collected from Gang-won, Chung-nam, and Jeju Province of Korea in 2008-2009. Three viruses, Lily symptomless virus (LSV), Lily mottle virus (LMoV), and Cucumber mosaic virus (CMV) were detected by RT-PCR. Virus-infected plant samples were identified; 12 plants with LSV, 20 plants with LMoV, and 1 plant with CMV. Of the twelve LSV infected samples, seven samples were found to be mix-infected with LMoV and LSV. Symptoms of LMoV and LSV mixed infection were fairly severe, like as vein clearing, leaf curling, leaf mottling, leaf mosaic, and yellow streaking. Mixed infection with LMoV and LSV was also found in lily bulbs which have been stored under unfavorable environmental conditions. LMoV predominated in our tests, whereas spread of Lilyvirus X (LVX) was not found. The nucleotide sequences of coat protein (CP) region of seven isolates (4 LMoV, 2 LSV, and 1 CMV) were compared with the corresponding regions of LMoV (AJ564636), LSV (AJ516059) and CMV(AJ296154). The nucleotide sequence homologies between reference viruses and seven isolates were 95-99%. Complete sequencing of seven isolates is necessary to obtain more information on the molecular characteristics of these viruses as well as to increase sensitivity and rapidity of viral detection.

• Journal of Animal Science and Technology
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• v.45 no.1
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• pp.33-40
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• 2003

The present study was undertaken to find relationships of plasma insulin-like growth factor (IGF)-I and IGF-II concentrations to litter size and lactation performance. Sixty pure-bred Landrace and Yorkshire pigs having similar farrowing weeks which had been selected from a large number of pregnant gilts and sows were divided into low- (<${\mu}$－0.5SD) and high-litter size (>${\mu}$+0.5 SD) lines under a 2 (breed)${\times}$2 (line) factorial arrange of treatments. After adjusting the litter size to nine piglets per sow at farrowing, total litter weight was measured at three weeks postpartum at weaning as an index of milk yield. Blood samples were obtained from the jugular vein at day (d)-90 pregnancy (Px) and at d-15 postpartum. The litter size or the number of piglets born during the present experiment and the average litter size during the entire parities up to the present one were greater in the high-line than in the low-line by 3.7 and 2.4 piglets, respectively (P<0.01); effect of the breed on litter size was not significant. Plasma IGF-II concentration at d-90 Px was greater in the high-line than in the low-line. Litter size and d-90 Px IGF-I concentration were negatively correlated in Landrace (r=－0.46; P<0.05) and tended to be negatively correlated in Yorkshire (r=－0.31; P=0.09), which resulted in a significant negative correlation between these two variables in total animals (r=－0.35; P<0.01). Litter weight at weaning was not different between the two breeds or lines. Relationships between the litter weight and IGF concentration were not consistent across the breed ${\times}$ physiological stage combinations. Results suggest that d-90 Px IGF concentrations may be indicative of the litter size at impending farrowing.

• Economic and Environmental Geology
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• v.37 no.2
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• pp.195-206
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• 2004

Paleomagnetic and rock-magnetic investigations have been carried out for the Cretaceous sedimentary rocks in the Poongam (also called Gapcheon) Basin in the eastern South Korea. A total of 128 independently oriented core samples were drilled from 13 sites for this study. The mean direction after bedding correction (D/I=353.1$^{\circ}$/55.6$^{\circ}$, k=21.5, =$$\alpha$_{95}$=10.1$^{\circ}$) is more dispersed than the mean direction before bedding correction (D/I=10.5$^{\circ}$/56.9$^{\circ}$, k=73.9, =$$\alpha$_{95}$=5.3$^{\circ}$), and the stepwise unfolding of the characteristic remanent magnetization (ChRM) reveals a maximum value of k at 20% unfolding. Secondary authigenic hematite accompanied by altered clays such as chlorite was identified by the electron microscope observations. These results collectively imply that the ChRM is remagnetized due to the formation of the secondary authigenic hematite after tilting of the strata. It is interpreted that the chemical remagnetization was connected to the introduction of mixed magmatic-meteoric fluids, which formed hydrothermal vein deposits near the study area. The paleomagnetic pole position (214.3$^{\circ}$E, 81.6$^{\circ}$N, =$A_{95}$=7.4$^{\circ}$) of the Cretaceous sedimentary rocks calculated from remagnetized directions is close to those of the Late Cretaceous and Tertiary poles of the Korean Peninsula. This Late Cretaceous to Tertiary remagnetization seems to be widespread over the Okcheon Belt because the chemical remagnetization is previously reported to be found in rocks from other Cretaceous small basins (e.g., Eumseong, Gongju and Youngdong basins) along the Okcheon Belt and some Paleozoic strata from the Okcheon unmetamorphosed zone.

• Economic and Environmental Geology
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• v.17 no.2
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• pp.115-139
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• 1984

The Cu-Pb-Zn-Ag hydrothermal vein-type deposits which comprise the Sambong mine occur within calc-alkaline volcanics of the Cretaceous Gyeongsang Basin. The ore mineralization took place through three distinct stages of quartz (I and II stages) and calcite veins (III stage) which fill the pre-existing fault breccia zones. These stages were separated in time by tectonic fracturing and brecciation events. The reflection variations of one mineral depending on mineralization sequence are considered to be resulted from variation in its chemical composition due to different physico-chemical conditions in the hydrothermal system. The reflection power of sphalerite increases with the content of Fe substituted for Zn. Reflectances of the sphalerite grain are lower on (111) than on (100) surface. The spectral profiles depend on the internal reflection color. Sphalerite, showing green, yellow and reddish brown internal reflection, have the highest reflection power at $544m{\mu}$ (green), $593m{\mu}$ (yellow) and $615m{\mu}$ (red) wavelength, respectively. Chalcopyrite is recognized as biaxial negative from the reflectivity data of randomly oriented grains measured at the most sensitivity at $544m{\mu}$. The microindentation hardness against the Fe content (wt. %) for the sphalerite increases to 8.05% Fe and then decreases toward 9.5% Fe content. Vickers hardness of the sphalerite is considerably higher on surface of (100) than on (111). The relationship between Vickers hardness and crystal orientation of the galena was determined to be $VHN_{(111)}$ > $VHN_{(210)}$ > $VHN_{(100)}$. The softer sulfides have the wider variation of the diagonal length in the indentation. Diagonal length in the indentation is pyrite

• Economic and Environmental Geology
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• v.22 no.3
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• pp.221-235
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• 1989

Gold-silver mineralization of the Goryeong-Waegwan area was deposited in three stages of quartz and calcite veins which fill fissures in Cretaceous sedimentary rocks of the Sindong Group. Radiometric dating indicates that mineralization is Late Cretaceous age(98 Ma) likely associated genetically with intrusion of a small biotite granite stock. Fluid inclusion and stable isotope data indicate that Au-Ag ore was deposited at temperatures between $280^{\circ}C$ and $230^{\circ}C$ from fluids with salinities between 1.7 and 8.7 equiv.wt.% NaCl. Evidence of boiling indicates pressures of <100 bars, corresponding to depths of 425 and 1,150m, respectively, assuming lithostatic and hydrostatic loads. Within ore stage I there is an apparent decrease in ${\delta}^{34}S$ values of $H_2S$ with paragenetic time, from +1.4 to -2.5 per mil. This pattern was likely achieved through progressive increases in pH and activity of oxygen accompanying boiling. Measured and calculated hydrogen and oxygen isotope values of ore-forming fluids(${\delta}D$ = -90 to -100 per mil; ${\delta}^{18}O$ = +3.9 to -11.4 per mil) indicate meteoric water dominance, approaching unex-changed meteoric water values. Au-Ag deposition is thought to be the result of cooling and dilution of a boiling fluid through mixing with less evolved meteoric waters.

• Applied Microscopy
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• v.36 no.3
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• pp.173-182
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• 2006

Recently, the pomegranate seed oil (PSO) has been reported to have various efforts including anti-cancer effect. In this study, we examined the liver-protecting effect of the PSO on the hepatotoxicity induced by $CCl_4$ using the BALB/c mice. The PSO was made from dried seeds of black pomegranate (Punica grantum) by heating and squeezing. The expreimental animals were divided into 3 groups; control group treated with olive oil only, experimental group 1 treated with $CCl_4$ only, and experimental group 2 treated with PSO and $CCl_4$. 24 hours after injection of $CCl_4$ into the peritoneal cavity, we collected the blood samples to measure the level of serological factors; aspartate aminotransferase(AST), alanine aminotransferase (ALT), total protein, albumin, total bilirubin, direct bilirubin and alkaline phosphatase. Simultaneously we observed the histological change of liver under the light and electron microscope. As the result, AST and ALT showed $88.7{\pm}14.9IU/L\;and\;22.0{\pm}3.12IU/L$ in the control group, $1963.7{\pm}1212.9IU/L\;and\;4495.4{\pm}2803.6IU/L$ in the experimental group 1, and $432.2{\pm}260.1IU/L\;and\;692.3{\pm}433.1IU/L$ in the experimental group 2. The experimental group 2 showed significant difference as compared with experimental group 1 (P<0.005). In histological study, the experimental group 2 was recovered than experimental group 1 which had abnormal mitochondria, increase of lysosomes, and severe necrosis at the central vein zones. These results indicated that the PSO had the liver protecting effect. However, The further study on the relationship between ingredients of pomegranate seed and liver protecting effect is in need.

• Economic and Environmental Geology
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• v.29 no.3
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• pp.235-246
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• 1996

Placer gold in collected heavy minerals from several localities in Huongkhe area, is consistently very finegrained (${\leq}100$ to $400{\mu}m$). The size and size distribution show somewhat differences at Dongdo and Hoahai : at Dongdo, predominant relatively larger and wide distribution; at Hoahai, characteristic relatively finer and narrow distribution range. The morphology of gold grains is divided into the four groups assumed by the dimension ratio : spherical, subprismoidal, prismoidal, and irregular. The gold grains at Dongdo show wide morphological distribution, whereas, at Hoahai, spherical form is predominant (${\approx}75%$). Three main types of gold are classified based on their chemical composition and mode of occurrence: type I (electrum; fineness=568~931), type II (amalgam; fineness=671~927), and type III (native gold; fineness=923~999). Type I gold contains, relatively high and variable silver contents (${\approx}11$ to 58 atomic % Ag), and has been classified into two subtypes based on their silver contents (type IA, ${\approx}11{\sim}39$ atomic % Ag; type IB, ${\approx}40{\sim}58$ atomic % Ag). However, type I gold would have been generally original compositions of electrum which originated at the provenance deposits. Mercury reacts with gold and silver to form amalgam (type II gold) which has variable Hg contents (1.2~30.5 atomic % Hg). The mercury contents in gold grains at Hoahai (10.9~30.5 atomic % Hg) are higher than those at Dongdo (5.8~21.1 atomic % Hg). The gold grains from the area generally exhibit a high-purity gold (type III) rim. The individual rims on the various grains range from <1 to $80{\mu}m$ in thickness and have silver contents of <10 atomic percent Ag, even though the core compositions range from ${\approx}11$ to 58 atomic percent Ag. The rim of gold most likely is responsible for the commonly cited cases of gold from placer deposits assaying at higher values of fineness than the gold in the corresponding source lode. The gold-rich rim in the Huongkhe area apparently forms by a combination of self-electrorefining and preferential dissolution of silver under oxidizing nature during the weathering and transport process. All data of gold grains in the Huongkhe area suggest that the transport distances and/or time of placer gold at Hoahai are generally farther than those at Dongdo. The mercurian gold bearing provenance deposits at Dongdo and Hoahai would be suggest nearest epithermal gold-silver vein-type.