• 제목/요약/키워드: Vegetative state

검색결과 59건 처리시간 0.028초

Isolation and Characterization of a Doritaenopsis Hybrid GIGANTEA Gene, Which Possibly Involved in Inflorescence Initiation at Low Temperatures

  • Luo, Xiaoyan;Zhang, Chi;Sun, Xiaoming;Qin, Qiaoping;Zhou, Mingbin;Paek, Kee-Yoeup;Cui, Yongyi
    • 원예과학기술지
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    • 제29권2호
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    • pp.135-143
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    • 2011
  • In the Doritaenopsis hybrid, like most of the orchid species and hybrids, temperature is crucial for the vegetative-to-reproductive transition, and low temperature is required for bud differentiation. To understand the molecular mechanism of this process, an orchid GIGANTEA (GI) gene, DhGI1, was isolated and characterized by using the rapid amplification of cDNA ends (RACE) PCR technique. Sequence analysis showed that the full-length cDNA is 4,022 bp with a major open reading frame of 3,483 bp, and the amino acid sequence showed high similarity to GI proteins in Zea mays, Oryza sativa, Arabidopsis thaliana and other plants. Semi-quantitative RT-PCR revealed that DhGI1 was expressed throughout development and could be detected in roots, stems, leaves, peduncles and flower buds. The expression level of DhGI1 was higher when the plants were flowering at low temperature (22/$18^{\circ}C$ day/night) than the other growth stages. Further analysis indicated that the accumulation of DhGI1 transcripts was significantly increased at low temperature, and concomitantly, initiation of the peduncle was observed. However, DhGI1 levels were low under high temperature (30/$25^{\circ}C$) conditions, and flower initiation was inhibited. These results indicate that the expression of DhGI1 is regulated by low temperature and that DhGI1 may play an important role in inflorescence initiation in this Doritaenopsis hybrid at low temperatures.

모싯잎 채취 시기별 성분 함량, ACE 및 AChE 저해 활성 (Component Content, ACE and AChE Inhibitory Activity of Ramie (Leaf Boehmeria nivea M.) according to Harvest Time)

  • 이종국;이정;조희제;김재경;최용민
    • 한국식품영양학회지
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    • 제31권2호
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    • pp.213-219
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    • 2018
  • This study was performed to determine the optimal time of harvest for ramie leaves with the two varieties (Seocheon Seobang and Seoncheon Baekpi) by comparison of physiological activity and physicochemical characteristics. The crude protein, minerals, ascorbic acid, folate, chlorophyll, ACE inhibitory activity and AChE inhibitory activity were determined. The amount of crude protein in ramie leaf, which was collected in Seocheon-gun, Chungcheongnam-do, grew up steadily from early May to September. The content of calcium in was higher in Baekpi than in Seobang. Seobang displayed its highest value of 3,569.90 mg% in September, while Baekpi displayed its highest value of 3,163.84 mg% in October. Although, folate and vitamin C contents in the two varieties were slightly different, they were higher as the growth date grew in October. The highest value of chlorophyll content was observed in October, which was later in the vegetative state. ACE inhibitory activity and AChE inhibitory activity appeared to be higher in Baekpi than in Seobang. Between June and August, ACE inhibitory activity was highest in Baekpi variety.

전두골 골절손상 환자의 임상 고찰 (Clinical Features of the Patients with Fracture on the Frontal Bone)

  • 김상현;황금;변진수;허철;홍순기;김헌주
    • Journal of Korean Neurosurgical Society
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    • 제29권3호
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    • pp.353-359
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    • 2000
  • Objective : The fracture on the frontal bone in head-injured patients may be commonly encountered in the clinical situations. Biomechanical studies demonstrate that the anterior wall of the frontal sinus is intermediate in its ability to resist fracture on direct impact. If the frontal sinus is large and the anterior table is able to disperse the force of the impact over a greater area, the posterior table and intracranial contents usually can be spared. We analyzed the clinical features of the patients who presented with frontal skull fracture due to frontal blows. Patients and Methods : From January, 1992 to December, 1997, 172 patients with frontal skull fracture were selected among 1911 patients with head injury who were admitted to department of neurosurgery. Clinical records and radiological studies of all patients were reviewed and evaluated retrospectively. Results : The neurobehavioral changes was seen in 34 cases(19.8%) and showed statistical significances in case of facial bone fractures, acute subdural hematoma(SDH), and positive frontal lobe releasing sign(p<0.05). The good glasgow outcome score group(GOS, good recovery & moderate disability) at discharge was revealed in 77.3% of total patient population. The poor GOS group(severe disability & vegetative state & death) at discharge was revealed in 22.7%. The poor GOS group at discharge have statistical significances with acute epidural hematoma(EDH), traumatic intraventricular hemorrhage(t-IVH), traumatic intracranial lesion, poor initial glasgow coma scale(GCS) scores & Revised Trauma Score(RTS)(p<0.05). Conclusion : Because of their anatomical relationships and neurobehavioral patterns due to vulnerability of the frontal lobe, the frontal injury should be considered as complicated facial injuries. Therefore, these patients are more likely to have a cosmetic or neuropsychiatric problems.

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한국들잔디 배아세포의 부유배양과 식물체 재생 (Embryogenic cell suspension culture and plant regeneration in zoysiagrass (Zoysia japonica Steud))

  • 팽왼주안;한리바우;퀴충휘;리다이엥;박태윤
    • 아시안잔디학회지
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    • 제23권2호
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    • pp.345-352
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    • 2009
  • 한국들잔디는 운동경기장이나 골프 코스 등에 폭넓게 쓰이는 난지형 잔디이다. 많은 품종은 영양체로 번식한다. 이 연구는 배아세포 유도와 식물체 재생을 위한 적정 배양액 개발과 배양조건을 연구하여, 한국잔디의 육종과 번식을 위한 세포배양 체계 확보를 목적으로 하였다. 그 결과 $Cu^{++}\;2.5mgL^{-1}$를 유도 배양액에 첨가하는 것이 캘러스 유도를 위한 최적 농도 조건 이였음을 보여주었다. Sub-culture의 횟수의 증가는 캘러스의 질을 향상시켰다. 세포 부유배양을 위한 최적 용량은 2.5에서 10mL 사이였으며 본 연구에서 58%의 식물체 재생산비율을 보였다.

Subtotal calvarial vault reconstruction utilizing a customized polyetheretherketone (PEEK) implant with chimeric microvascular soft tissue coverage in a patient with syndrome of the trephined: A case report

  • Wang, Jessica S.;Louw, Ryan P. Ter;DeFazio, Michael V.;McGrail, Kevin M.;Evans, Karen K.
    • Archives of Plastic Surgery
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    • 제46권4호
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    • pp.365-370
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    • 2019
  • The syndrome of the trephined is a neurologic phenomenon that manifests as sudden decline in cognition, behavior, and sensorimotor function due to loss of intracranial domain. This scenario typically occurs in the setting of large craniectomy defects, resulting from trauma, infection, and/or oncologic extirpation. Cranioplasty has been shown to reverse these symptoms by normalizing cerebral hemodynamics and metabolism. However, successful reconstruction may be difficult in patients with complex and/or hostile calvarial defects. We present the case of a 48-year-old male with a large cranial bone defect, who failed autologous cranioplasty secondary to infection, and developed rapid neurologic deterioration leading to a near-vegetative state. Following debridement and antibiotic therapy, delayed cranioplasty was accomplished using a polyetheretherketone (PEEK) implant with free chimeric latissimus dorsi/serratus anterior myocutaneous flap transfer for vascularized resurfacing. Significant improvements in cognition and motor skill were noted in the early postoperative period. At 6-month follow-up, the patient had regained the ability to speak, ambulate and self-feed-correlating with evidence of cerebral/ventricular re-expansion on computed tomography. Based on our findings, we advocate delayed alloplastic implantation with total vascularized soft tissue coverage as a viable alternative for reconstructing extensive, hostile calvarial defects in patients with the syndrome of the trephined.

맥문동(麥門冬)의 재식밀도(栽植密度)에 따른 생육(生育) 및 수양성(收量性) (Growth and Tuber Yield of Liriope platyphylla WANG and TANG in Different Planting Density)

  • 성재덕;박용진;김현태;서형수;한경수
    • 한국약용작물학회지
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    • 제2권2호
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    • pp.110-113
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    • 1994
  • 맥문동(麥門冬) 재식밀도(栽植密度)에 따른 생육(生育) 및 수양성(收量性)을 구명(究明)코자 맥문동(麥門冬) 1호(號)를 공시(供試)하여 재식밀도(栽植密度)는 조간(條間) $20cm{\times}$ 주간(株間) 10cm, $30{\times}10cm$, $30{\times}30cm$의 4수준(水準)으로 하고 주당본수(株當本數)는 2,4,6본(本)으로 4월(月) 10일(日)에 정식(定植)하여 시험(試驗)을 실시(實施)한 결과(結果)를 요약(要約)하면 다음과 같다. 1. 시험포장(試驗圃場) 토양(土壤)의 이화학적(理化學的) 특성(特性)은 중점토(重點土)로 유기물(有機物), 유효린산(有效隣酸), Ca, Mg는 전국치(全國値)보다 낮은 반면, K, C.E.C.함량(含量)은 높았다. 2. 재식밀도(栽植密度)에 다른 맥문동(麥門冬)의 지토부(地土部) 생육(生育)은 밀치(密値)에 비하여 소치(疎値)할수록, 잎은 크고, 분얼수(分蘖數)도 많았으며, 경엽중(莖葉重)은 무거운 경향(傾向)이었다. 재식밀도별(栽植密度別) 지토부(地土部)의 수양구성요소(收量構成要素) 및 수양성(收量性)은 재식거리(栽植距離) $\30{\times}10$ 재식본수(栽植本數) 6본(本)으로 정식(定植)한 것이 괴근수(塊根數)가 43개(個)로서 많았고, 건근수률도 372kg /10a로 높았다. 4. 각형질간(各形質間)의 상관관계(相關關係)를 보면 분얼수(分蘖數) 뿌리무게, 괴근수간(塊根數間)에 유혜성(有蕙性)이 있었고, 괴근수(傀根數)와 수양간(收量間)에도 고도(高度)의 정(正)의 상관(相關)을 보였다.

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2010년 주요 의료 판결 분석 (Review of 2010 Major Medical Decisions)

  • 이정선;서영현;유현정
    • 의료법학
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    • 제12권1호
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    • pp.177-225
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    • 2011
  • Verdicts related to major medical litigation given by the Seoul Central District Court, the Seoul High Court and the Supreme Court in 2010 were analyzed. It's shown that in cases of the medical negligence regarding the occurrence of neonatal cerebral palsy, the plaintiff claims were dismissed using criteria proposed by associations of Obstetrics and Gynecology and Pediatrics in US, and thereof the burden of plaintiffs to prove the medical negligence has increased. In addition, in case of that the expected survival period of infants gets longer, payments for treatment and nursing after survival period determined by judges are made and it was judged to compensate it as a periodical indemnity. In case for the explanation obligation the most frequently mentioned in the medical litigation, in addition to cases of invoking the existing theory of explanation obligation, verdicts to mention the instructions of theory regarding instruction explanation obligation and the possibility of compensation for damages on property are given. Particularly, in cases for a liability of reparation by exaggerating the effects and not disclosing the risks related to treatment with stem cells, even if the treatment not approved by Food and Drug Administration is in violation of the Pharmaceutical Affairs Law, it's not illegal as violation in Pharmaceutical Affairs Law itself. But there is a certain verdict to present the possibility of an extension of the theory of explanation obligation by acknowledging the liability of reparation caused by illegal acts with no explanations of effects and risks of treatment with stem cell by doctors and pharmaceutical companies. In an incident in which a mental patient fell and died through the opened door of the roof at the hospital, a liability of reparation was acknowledged due to defects in structure installation management and this verdict drew an attention since the overall management responsibility about patients including structures was acknowledged to the hospital besides the obligations on medical practice. In case of the verdict without giving the opportunity to state the opinion with respect to the main legal issues, the responsibility of the court was emphasized since the court did not fulfill the explanation obligations. There were some cases in which payments for nursing and caring to a patient in vegetative state during the plastic surgery was admitted. However, in dental-related incidents, the proportion of cases in which plaintiff won was low since the difficulty of proving may be reflected. In the area of administrative litigation, unlike the existing position regarding arbitrary medical charge cover collected from patients in hospital, the verdict to admit the legitimacy of collection of medical treatment was given and attracted the attention of people. Verdict in which the expression related to medical advertisement was not exaggerated disposed the original verdict and pointed out the problem of excessive regulations on medical advertisement. The effort to analyze the trend of verdicts of court through reviewing the decisions and to organize should be continued, but the full decision should be disclosed as a base, and people and systems to enable the all time monitoring should be prepared.

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지능형 스마트 팜 활용과 생산성에 관한 연구: 토마토 농가 사례를 중심으로 (Intelligent Smart Farm A Study on Productivity: Focused on Tomato farm Households)

  • 이재경;설병문
    • 벤처창업연구
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    • 제14권3호
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    • pp.185-199
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    • 2019
  • 한국의 시설원예는 짧은 기간에 주목할 만큼 발전하였지만, 높은 경영비와 시장개방 등 불리한 주변 여건에 대응하여 국제경쟁력을 확보하기 위해서는 시설원예의 문제점 진단과 분석을 통하여 대응책을 마련하여야 한다. 본 연구는 스마트 팜을 2세대 지능형 스마트 팜으로 발전시키기 위한 목적을 가지고 있다. 이를 위하여 선도사례와 실증사례 연구를 통해 작물 생육 정보의 활용 및 분석 능력이 생산성에 어떠한 영향을 미치는지 실증사례를 통하여 고찰한다. 정보통신기술(ICT)을 도입한 시설원예 스마트 팜과 빅데이터를 활용한 농업기술이 농가의 생산성에 어떤 기여를 하고 있는지에 대하여 선도농가의 사례를 분석하였다. 이와 함께 작물 생육 정보 수집 및 분석 솔루션을 개발하여 수경재배 토마토 농가에서 산출된 생산성 변화 요인을 분석하였다. 본 연구의 결과는 첫째, 작물 생육 정보 엽온의 활용 필요성이다. 엽온의 활용 범위는 시설 내 하우스 환기, 보온 커튼의 열고 닫음, 최초 관수 시점과 종료 시점 결정 등 다양하게 활용할 수 있다는 것을 확인하였다. 둘째, 작물 생육 정보 함수율의 활용 필요성이다. 작물 생육 함수율 정보는 작물의 현재 상태가 영양 생장인지, 생식 생장인지를 확인 가능하게 하며, 광합성 능력에 따라 함수율을 인위적으로 조절할 수 있다는 것이 확인되었다. 셋째, 작물의 EC, pH 정보를 활용하는 것이다. 작물에 따라 기후조건에 따라 EC 값을 달리해야 한다. 공급되는 EC, pH와 배액에서 측정되는 EC, pH를 비교하여 현재 작물의 생육 상태를 확인할 수 있다는 것이 확인되었다. 본 연구의 결과를 토대로 스마트 팜의 측정 생육 정보를 어떻게 활용하는가에 따라 생산성에 영향을 미칠 수 있다는 것을 확인할 수 있었다.

무의미한 연명치료 중단 등의 기준에 관한 재고 - 대법원 2009.5.21 선고 2009다17417사건 판결을 중심으로 - (Review on the Justifiable Grounds for Withdrawal of Meaningless Life-sustaining Treatment -Based on a case of Supreme Court's Sentence No. 2009DA17417 (May 21, 2009)-)

  • 문성제
    • 의료법학
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    • 제10권2호
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    • pp.309-341
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    • 2009
  • According to a case of Supreme Court's Sentence No. 2009DA17417 (May 21, 2009), the Supreme Court judges that 'the right to life is the ultimate one of basic human rights stipulated in the Constitution, so it is required to very limitedly and conservatively determine whether to discontinue any medical practice on which patient's life depends directly.' In addition, the Supreme Court admits that 'only if a patient who comes to a fatal phase before death due to attack of any irreversible disease may execute his or her right of self-determination based on human respect and values and human right to pursue happiness, it is permissible to discontinue life-sustaining treatment for him or her, unless there is any special circumstance.' Furthermore, the Supreme Court finds that 'if a patient who is attacked by any irreversible disease informs medical personnel of his or her intention to agree on the refusal or discontinuance of life-sustaining treatment in advance of his or her potential irreversible loss of consciousness, it is justifiable that he or she already executes the right of self-determination according to prior medical instructions, unless there is any special circumstance where it is reasonably concluded that his or her physician is changed after prior medical instructions for him or her.' The Supreme Court also finds that 'if a patient remains at irreversible loss of consciousness without any prior medical instruction, he or she cannot express his or her intentions at all, so it is rational and complying with social norms to admit possibility of estimating his or her own intentions on withdrawal of life-sustaining treatment, provided that such a withdrawal of life-sustaining treatment meets his or her interests in view of his or her usual sense of values or beliefs and it is reasonably concluded that he or she could likely choose to discontinue life-sustaining treatment, even if he or she were given any chance to execute his or her right of self-determination.' This judgment is very significant in a sense that it suggests the reasonable orientation of solutions for issues posed concerning withdrawal of meaningless life-sustaining medical efforts. The issues concerning removal of medical instruments for meaningless life-sustaining treatment and discontinuance of such treatment in regard to medical treatment for terminal cases don't seem to be so much big deal when a patient has clear consciousness enough to express his or her intentions, but it counts that there is any issue regarding a patient who comes to irreversible loss of consciousness and cannot express his or her intentions. Therefore, it is required to develop an institutional instrument that allows relevant authority to estimate the scope of physician's medical duties for terminal patients as well as a patient's intentions to withdraw any meaningless treatment during his or her terminal phase involving loss of consciousness. However, Korean judicial authority has yet to clarify detailed cases where it is permissible to discontinue any life-sustaining treatment for a patient in accordance with his or her right of self-determination. In this context, it is inevitable and challenging to make better legislation to improve relevant systems concerning withdrawal of life-sustaining treatment. The State must assure the human basic rights for its citizens and needs to prepare a system to assure such basic rights through legislative efforts. In this sense, simply entrusting physician, patient or his or her family with any critical issue like the withdrawal of meaningless life-sustaining treatment, even without any reasonable standard established for such entrustment, means the neglect of official duties by the State. Nevertheless, this issue is not a matter that can be resolved simply by legislative efforts. In order for our society to accept judicial system for withdrawal of life-sustaining treatment, it is important to form a social consensus about this issue and also make proactive discussions on it from a variety of standpoints.

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수량화(數量化)(II)에 의한 산사태사면(山沙汰斜面)의 위험도(危險度) 판별(判別) (On the Determination of Slope Stability to Landslide by Quantification(II))

  • 강위평;무라이 히로시;오무라 히로시;마호섭
    • 한국산림과학회지
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    • 제75권1호
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    • pp.32-37
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    • 1986
  • 산사태안전도판별(山沙汰安全度判別)에 대한 기초자료를 얻기 위하여 1979년(年) 8월(月) 집중호우(集中豪雨)(일강우량(日降雨量) 465mm)에 의하여 산사태(山沙汰)가 발생한 진해지구(鎭海地區)를 모델로 하여 이 지구(地區)의 지형도상(地形圖上)($S=\frac{1}{5,000}$)에 $2cm{\times}2cm$(실면적(實面積) $100m{\times}100m=1ha$) 단위의 격자(格子)를 얹어 산사태지(山沙汰地) 74개, 비산사태지(非山沙汰地) 119개 계(計) 193개의 mesh에 대하여 산사태발생(山沙汰發生)의 각(各) 요인(要因) 및 수준(水準)을 계측(計測)하여 수량화(數量化)(II)의 수법(手法)에 의하여 해석(解析)한 결과 산사태발생(山沙汰發生)에 기여도(寄與度)가 높은 요인(要因)의 순위(順位)는 다음과 같다. 1) 식생(植生), 2) 종단사면형(縱斷斜面形), 3) 사면위치(斜面位置), 4) 경사(傾斜), 5) 방위(方位), 6) 곡수(谷數). 또 침엽수(針葉樹) 10년생(年生) 내외, 복합사면(複合斜面), 하강사면(下降斜面), 산록(山麓), 경사(傾斜), $10^{\circ}-15^{\circ}$, 방위(方位) NW, 곡수(谷數) 1개의 각(各) 수준(水準)이 불안전측(不安全側)에, 침엽수(針葉樹) 20~30년생(年生), 활엽수(濶葉樹), 상승사면(上昇斜面), 평형사면(平衡斜面), 산정(山頂) 등의 수준(水準)이 안전측(安全側)에 기여(寄與)하고 있다. 그리고 판별구분치(判別區分値)는 -0.123이고 적중률(適中率)은 72%로서 비교적 양호한 양(兩) group구분(區分)을 할 수 있었다.

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