• 제목/요약/키워드: Variance Analysis of Variance(ANOVA)

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시판 이소니아짓 정제의 생물학적 동등성시험에 관한 연구 (Studies on the Bioequivalence Test of Isoniazid Tablets)

  • 최준식;안선엽
    • 약학회지
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    • 제33권4호
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    • pp.229-236
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    • 1989
  • Even though two different preparations are chemically equivalent, the variance of bioavailability differenciates the clinical effect of preparations, so that the preparations need to be evaluated by comparing bioavailability in vivo as well as chemical equivalence. In this study, bioequivalence tests of commercially available isoniazid tablets A, B, C and D (standard) were performed to give some guidelines to bioequivalence test. The bioavailability parameters obtained by drug administeration were statistically analyzed. Statistical evaluation of the data involved an analysis of variance for a cross over design. Cross over design was employed with 8 healthy volunteers. The results were within 20% difference of mean value in the AUC, Cmax, Tmax and amount of urinary excretion (Au) between standard and isoniazid tablets. The results of ANOVA showed no significant differences for 'group or sequence', but almost not for 'between subjects'. The tablet. A, B and D were within 20 min, but tablet C was within 50 min. Tablet A was biologically equivalent in the Au. tablet B biologically equivalent in the Au and AUC. Tablet C was biologically equivalent in the Au. The relationship between the dissolution rate and Au was significant.

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사영에 의한 확률효과모형의 분석 (The analysis of random effects model by projections)

  • 최재성
    • Journal of the Korean Data and Information Science Society
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    • 제26권1호
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    • pp.31-39
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    • 2015
  • 본 논문은 확률효과모형에서 사영에 근거한 분산성분을 구하는 방법을 다루고 있다. 분산성분을 추정하기 위한 ANOVA방법에서 제곱합의 계산에 사영을 이용하는 방법을 제시하고 있다. 분산성분을 구하기 위한 사영의 이용은 모형행렬에 의한 사영공간을 분산성분별 제곱합을 얻기 위한 상호직교하는 부분공간들로 분할하게 된다. 부분공간들로 분할하기 위해 모형행렬 X로의 사영에 단계별 방법(stepwise procedure)을 적용하여 해당하는 공간으로의 사영행렬을 구하는 방법을 다루고 있다. 단계별 방법에 의해 주어지는 부분공간들의 직교성으로 인해 사영행렬의 곱은 영행렬로 주어지는 성질을 갖는다. 단계별 방법에 의한 순차적 사영은 해당하는 공간으로의 사영행렬에 대한 확인과 사영행렬의 구조를 파악할 수 있는 이점이 있다. 또한 분산성분의 추정을 위한 제1종 제곱합을 구하기 위한 방법으로 유용하다.

사무소 건설의 설계변수 열성능 평가 및 부하예측방정식 개발 (Thermal Performance Evaluation of Design Parameters and Development of Load Prediction Equations of Office Buildings)

  • 석호태;김광우
    • 설비공학논문집
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    • 제13권9호
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    • pp.914-921
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    • 2001
  • The objective of this study is to evaluate the design parameters and to develop the cooling and heating load prediction equations of office buildings. The building load calculation simulation was carried out using the DOE-2.1E program. The results of the simulation was used as a data for ANOVA and multiple regression analysis which could develop the load prediction equations.

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아파트의 층수와 주거인구가 생활용수량(生活用水量)에 미치는 영향(影響) (Effect on the amount of domestic water use by the water pressure and the number of a family in each house)

  • 현인환;지병준;이상준;이제인
    • 상하수도학회지
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    • 제14권3호
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    • pp.217-223
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    • 2000
  • This study is to investigate the effect on the mount of domestic water use by the water pressure and the number of a family for the each house. Tow apartment sites which had elevated water tanks on the roof were selected as the reserch area. Tow techniques such as Analysis of Variance(ANOVA) and Analysis of Correlation were used for the analysis.

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Analysis of Cutting Properties with Reference to Amount of Coolant used in an Environment-Conscious Turning Process

  • Yang, Seung-Han;Lee, Young-Moon;Kim, Young-Suk
    • Journal of Mechanical Science and Technology
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    • 제18권12호
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    • pp.2182-2189
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    • 2004
  • In the recent years, environmentally conscious design and manufacturing technologies have attracted considerable attention. The coolants, lubricants, solvents, metallic chips and discarded tools from manufacturing operations will harm our environment and the earth's ecosystem. In the present work, the Tukey method of multiple comparisons is used to select the minimum level of coolant required in a turning process. The amount of coolant is varied in 270 designed experiments and the parameters cutting temperature, surface roughness, and specific cutting energy are carefully evaluated. The effects of coolant mix ratio as well as the amount of coolant on the turning process are studied in the present work. The cutting temperature and surface roughness for different quantity of coolant are investigated by analysis of variance (ANOVA) - test and a multiple comparison method. ANOVA-test results signify that the average tool temperature and surface roughness depend on the amount of coolant. Based on Tukey's Honestly Significant Difference (HSD) method, one of the multiple comparison methods, the minimum level of coolant is 1.0 L/min with 2% mix ratio in the aspect of controlling tool temperature. F-test concludes that the amount of coolant used does not have any significant effect on specific cutting energy. Finally, Tukey method ascertains that 0.5 L/min with 6% mix ratio is the minimum level of coolant required in turning process without any serious degradation of the surface finish. Considering all aspects of cutting, the minimum coolant required is 1.0 L/min with 6% mix ratio. It is merely half the coolant currently used i.e. 2.0 L/min with 10% mix ratio. Minimal use of coolant not only economically desirable for reducing manufacturing cost but also it imparts fewer hazards to human health. Also, sparing use of coolant will eventually transform the turning process into a more environment-conscious manufacturing process.

실험계획법에 의한 Al/SiC 복합재료의 최적공정 설계 (Optimal Parameter Design for Al/SiC Composites using Design of Experiments)

  • 이광진;김균택;김영식
    • 동력기계공학회지
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    • 제15권5호
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    • pp.72-76
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    • 2011
  • In this work, the parameter optimization for thermal-sprayed Al/SiC composites have been designed by $L_9(3^4)$ orthogonal array and analysis of variance(ANOVA). Al/SiC composites were fabricated by flame spray process on steel substrate. The hardness of composites were measured using micro-vickers hardness tester, and these results were analyzed by ANOVA. The ANOVA results showed that the oxygen gas flow, powder feed rate and spray distance affect on the hardness of the Al/SiC composites. From the ANOVA results, the optimal combination of the flame spray parameters could be extracted. It was considered that experimental design using orthogonal array and ANOVA was efficient to determine optimal parameter of thermal-sprayed Al/SiC composites.

A Sensitivity Analysis of Parameters Affecting Indoor Air Quality Related to TVOC and HCHO Reduction

  • Kang, Hae Jin;Kim, Mi Yeon;Rhee, Eon Ku
    • Architectural research
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    • 제14권3호
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    • pp.93-98
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    • 2012
  • The objective of the study is to analyze the relative performance of factors affecting indoor air quality in multi-residential buildings in Korea. A study of the factors affecting indoor air quality is essential for establishing indoor air quality management strategies effectively. To observe the indoor air quality response following a modification of a given parameter, a sensitivity analysis was performed. The factors examined for the analysis include; wall/ceiling paper, adhesive for wall/ceiling paper, floor material, adhesive for floor material, and ventilation rate. The Experimental Design which identifies main effects among the design parameters with a few experiments was used to decrease the number of experiments. The simulation for indoor air quality was undertaken using a validated equation. Then, ANOVA(Analysis of Variance) was performed to evaluate the relative importance of each parameter affecting the indoor air quality. The result of the study indicates that the indoor air quality may be influenced most by adhesive for wall/ceiling paper, followed by ventilation rate and adhesive for floor material.

소비자의 환경의식과 의생활 행동과의 관련성 (Environmental Perception of Consumers and Clothing Consumption Behavior)

  • 박화순
    • 대한가정학회지
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    • 제36권10호
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    • pp.79-88
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    • 1998
  • The purpose of this study is to identify environmental perception of clothing consumption behavior taking socioo-economic variables into account. An instrument, based on previous research was administered to 213 housewives in Taegu area. In analyzing the data, factor analysis, t-test, ANOVA, regression analysis were used. The finding of this indicated that the environmental perception of clothing consumption were significant in purchasing, managing, and disposal of clothing. Among socio-economics variables, income and educational level were found to be significant in explaining the variance of enviromental perception behavior of clothing consumption. The important results of this study are discussed and implications are provided.

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실험계획법에 의한 플라즈마침적 공정변수 영향분석 (Analysis of Process Variables on Plasma Deposition by Experimental Design)

  • 정인하;박희성;이철용;강권호;문제선
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 1999년도 춘계학술발표강연 및 눈문개요집
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    • pp.57-57
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    • 1999
  • 핵연료 펠렛제조공정의 단순화를 위하여 분말을 플라즈마로 용융시킨 후 이를 펠렛몰더에 직접 침적시키는 방법으로 핵연료를 제조하고자 하였다. 침적물의 밀도에 미치는 영향을 관찰하기 위하여 쉬스가스 조성, 플라즈마 동력, 챔버내부압력 및 분말 공급량, 입자크기, 분사관 위치, 분사거리 및 쉬스가스조성 등을 변수로 하였다$^{1)}$ . 실험으로 얻어진 결과는 ANOVA(Analysis of Variance)의 통계적 방법으로 각각의 인자가 밀도에 미치는 영향의 크기뿐만 아니라, 두 가지 이상의 인자가 조합되어 나타나는 영향에 대해서도 분석하였다.

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Predicting bond strength of corroded reinforcement by deep learning

  • Tanyildizi, Harun
    • Computers and Concrete
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    • 제29권3호
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    • pp.145-159
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    • 2022
  • In this study, the extreme learning machine and deep learning models were devised to estimate the bond strength of corroded reinforcement in concrete. The six inputs and one output were used in this study. The compressive strength, concrete cover, bond length, steel type, diameter of steel bar, and corrosion level were selected as the input variables. The results of bond strength were used as the output variable. Moreover, the Analysis of variance (Anova) was used to find the effect of input variables on the bond strength of corroded reinforcement in concrete. The prediction results were compared to the experimental results and each other. The extreme learning machine and the deep learning models estimated the bond strength by 99.81% and 99.99% accuracy, respectively. This study found that the deep learning model can be estimated the bond strength of corroded reinforcement with higher accuracy than the extreme learning machine model. The Anova results found that the corrosion level was found to be the input variable that most affects the bond strength of corroded reinforcement in concrete.