• 한국산학기술학회논문지
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• 제19권6호
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• pp.447-454
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• 2018

본 연구의 목적은 지역사회건강조사 자료를 이용하여 우리나라 성인 당뇨병 환자에서 인플루엔자 예방접종률과 예방접종 관련요인을 알아보고자 하는 것이다. 본 연구는 2015년 지역사회건강조사 원시자료를 이용하였으며, 만 19세 이상 성인 총 228,261명을 최종 연구대상자로 선정하였다. 인플루엔자 백신 접종 관련요인을 파악하기 위하여 대상자의 인구사회학적 요인(연령, 성별, 교육수준, 가구소득, 거주 지역, 결혼상태 및 직업유무), 건강행태(흡연, 음주 및 건강검진), 질병 이환(비만, 고혈압 및 이상지질혈증) 및 주관적 건강상태를 교차분석 및 로지스틱 회귀분석으로 분석하였다. 본 연구 결과 우리나라 성인 당뇨병 환자의 인플루엔자 백신 접종률은 62.4%로 낮은 수준이다. 인플루엔자 예방접종 여부를 종속변수로 모든 변수가 보정된 상태에서 당뇨군에서는 연령, 성별, 교육수준, 거주 지역, 결혼상태, 직업유무, 흡연, 건강검진 및 동반질환이 유의한 변수로 나타났다(p<0.05). 따라서 당뇨병 환자에서 인플루엔자 백신 접종률을 향상시키기 위해서는 예방접종에 대한 인식증대를 위한 체계적인 교육과 홍보가 필요하며, 무료접종 확대 실시와 같은 국가적 정책도 필요하겠다.

• Journal of Preventive Medicine and Public Health
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• 제33권1호
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• pp.109-116
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• 2000

Objectives : Routine vaccination against influenza is recommended for all people aged 65 years or more. Without active encouragement to receive the vaccine, the rate of compliance is generally low. A study was undertaken to assess and compare the effectiveness of two reminder systems in improving the influenza vaccination rate. Methods : A total of 2,017 patients aged 65 or over in a tertiary care hospital family practice center were randomly assigned to a control, a telephone reminder, or a postcard reminder group before the influenza season in 1998. The outcome measure, receipt of vaccination, was determined by telephone interview. Demographic and clinical characteristics were checked through the medical chart review. Results : Among the 1,312 patients who actually received reminders and interviewed, the vaccination rate was 46.7% in the control group, 56.3% in the postcard reminder group, and 63.3% in the telephone reminder group. Vaccination compliance was significantly higher in people reminded by telephone (Odds ratio [OR], 2.00; 95% confidence interval [CI], 1.52-2.64) and postcard (OR, 1.55; 95% CI, 1.18-2.02) compared to that in the control group. Of the characteristics investigated, number of high risk co-morbidity was positively associated with vaccination compliance while current smoking was negatively associated. Conclusions : This result suggests that telephone and postcard reminders can significantly improve compliance with influenza vaccination in this group of Korean elderly. However, additional strategies need to be developed to encourage vaccination among noncompliant.

• Journal of Korean Biological Nursing Science
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• 제23권4호
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• pp.318-329
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• 2021

Purpose: This study was conducted to identify factors affecting COVID-19 vaccination and associated side effects among health care workers in a small and medium-sized hospital. Methods: In May 2021, 301 workers out of a total of 670 working in a small and medium-sized hospital in Gyeonggi-do, were surveyed. The small and medium-sized hospital treats patients with COVID-19. Health care workers across different medical institutions responded with self-reported internet questionnaires. Factors influencing COVID-19 vaccination were analyzed via logistic regression. Results: Out of 301 subjects, 89.0% showed an intention to inoculate, and 85.7% were vaccinated against COVID-19. The most frequent reason for vaccination was responsibility as a medical worker. The fear of adverse reactions was the most frequent reason for non-vaccination. Adverse reactions after inoculation occurred in 70.9% of cases, and 30.6% were referred for treatment of adverse reactions. The factors ultimately influencing COVID-19 vaccination were vaccination intention, previous side effects from other vaccinations, occupation, and age. Conclusion: In order to improve the effectiveness of COVID-19 vaccination, a systematic approach is required to determine the risk factors associated with the young age of the administrative staff/personnel, subjects with a history of side effects associated with other vaccines, and health care workers who do not intend to be vaccinated. It is important to develop strategies to improve immunization. In addition, accurate and essential information regarding the side effects of vaccination is needed, along with appropriate education and publicity.

• 문화기술의 융합
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• 제8권2호
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• pp.299-307
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• 2022

본 연구는 성인 만성폐쇄성폐질환(Chronic Obstructive Pulmonary Disease, COPD) 환자의 인플루엔자 접종률과 접종에 영향을 미치는 요인을 파악하기 시행하였다. 2014년부터 2018년까지 5년간의 국민건강영양조사에 참여한 대상자 중 만 40세 이상이며 폐기능 검사 판정결과 폐쇄성환기장애(FEV1/FVC<0.7)로 나타난 2,370명을 대상으로 인플루엔자 예방접종률과 접종에 미치는 영향요인을 분석하였다. 민간강영양조사 데이터를 분석한 결과 만 40세 이상 성인 COPD 환자의 인플루엔자 예방접종률은 59.2%이었으며, 예방접종에 영향을 미치는 요인은 65세 이상, 낮은 경제수준, 과거흡연자이거나 비흡연자, 최근 2년 이내 건강검진을 받은 경우이었다. COPD가 있는 성인의 예방접종률을 높이기 위하여 인플루엔자 예방접종에 영향을 주는 요인들을 고려하여 예방접종률을 높이기 위한 방안을 모색해야 할 것이다.

• 한국산학기술학회논문지
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• 제17권3호
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• pp.464-472
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• 2016

본 연구는 간호대학생들을 대상으로 인유두종바이러스(HPV) 예방접종에 영향을 미치는 요인을 조사하였다. 연구대상은 G광역시에 소재하는 3개 대학의 간호학생 604명이었다. 자료수집은 2015년 6월부터 10월까지 이루어졌으며, SPSS 21.0 program을 이용하여 분석하였다. 대상자 가운데 HPV 예방접종군은 14.7%, 비접종군은 85.3%로 나타났다. 예방접종여부와 연령, 학년, 성별, 용돈, 예방접종에 대해 들어본 경험은 통계적으로 연관이 있었다(p<.001). 대상자의 암 예방행위 점수는 평균 7.22점, 건강신념은 평균 24.71점이었다. 예방접종군의 결정요인은 '부모님 또는 주변인의 권유'가 가장 많았고, 비접종군의 장애요인은 '관심이 없어서'가 가장 많았다. HPV 예방접종에 영향을 미치는 유의한 요인은 학년, 용돈, 예방접종에 대해 들어본 경험, HPV 예방접종 관련 건강신념이었다. 특히 HPV 예방접종에 대해 들어본 경험이 없는 대상자 보다 경험이 있는 대상자의 예방접종률이 높았다(OR=8.59, p<.001). 본 연구의 결과는 간호대학생들의 HPV 예방접종에 대한 제한된 지식에 기여할 수 있을 것이다. 또한 예방접종률 증진을 위한 기초자료로써 유용하게 활용될 것으로 사료된다.

• 농촌의학ㆍ지역보건
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• 제27권1호
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• pp.125-142
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• 2002

This study was carried out to purpose drawing up the efficient method of rural residents' health management, analyzing factors having influences on the behavioral intention and the behavior of hepatitis B vaccination of rural residents, using the theory of planned behavior(TPB). Surveying the first questionnaire about TPB to 439 people of rural adults over 40-year old who participated to hepatitis B examination program was made from March 14 to April 23 in 2001 at two primary health care posts in a city in Gyeongsangbuk-do and the second survey for hepatitis B vaccination was made to the last subjects of 332 people(75.6%) that had been proved as subjects of inoculation against the hepatitis B as the result of examination after two months of notification. In the behavioral intention rate of hepatitis B vaccination of the subjects within a month, 100%(the top) was 45.2%, 80-90%(the middle) was 21.1% and under 70%(the low) was 33.7%. In simple analysis, vaccination intention was related with significantly health security type and economic status(p<0.05). And vaccination intention was related with significantly all variables of attitude toward behavior and subjective norm, and economic power of utilizing medical facilities and perceived power variable of perceived behavioral control(p<0.01). The vaccination rate of the subjects within a month was 31.3%. In simple analysis, the vaccination rate was higher significantly in the lower the age was, the higher the educational level was(p<0.01), the larger the family was, and subjects having transport(p<0.05). And the vaccination rate was higher in the higher the economic power was and the higher the perceived ability was. As the results of making generalized logit analysis for behavioral intention, the more positive the subjective norm was, the higher was the score of the perceived behavioral control, the intention was higher significantly in the top class on a basis of the low class of behavioral intention. In multiple logistic regression analysis for vaccination(behavior) using intention and perceived behavioral control as dependent variables, it showed that perceived behavioral control variable only influenced significantly. The higher was the score of perceived behavioral control, it showed that they got the more vaccination(p<0.01). And even in the result having analyzed, adding the significant general characteristics variables in the simple analysis to the independent variable, the higher was the score of perceived behavioral control, it showed that they got vaccination more.

• 농촌의학ㆍ지역보건
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• 제41권3호
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• pp.119-128
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• 2016

이 연구는 대학생의 A형 간염 지식, 건강신념, A형 간염 예방접종 행태를 파악하기 위하여 실시하였다. 대구 경북지역의 보건계열을 제외한 4년제 대학생을 대상으로 2014년 3월 3일부터 3월 25일까지 구조화된 설문지를 이용한 자기기입식 설문조사를 하였으며, 총 197부를 최종분석대상으로 하였다. 연구대상자들의 A형 간염 지식점수는 15점 만점에 $4.59{\pm}3.06$점이었으며, 건강신념 점수는 4점 만점에 $2.39{\pm}0.28$점이었고, A형 간염 예방접종률은 12.7%였다. A형 간염 지식은 A형 간염 검사 경험, 가족 중 A형 간염 예방접종 경험에 따라 유의한 차이가 있었고, 건강신념은 성별에 따라 유의한 차이가 있었다. A형 간염 예방접종은 A형 간염 검사 경험, 가족 중 간질환, 가족 중 A형 간염 예방접종 경험, A형 간염 교육 경험 등에 따라 유의한 차이가 있었다. 로지스틱 회귀분석 결과, A형 간염 예방접종 행태에 유의한 영향을 미치는 변수는 A형 간염 검사 경험과 가족 중 A형 간염 예방접종 경험이었다. 결과적으로 연구대상자들의 A형 간염 지식, 건강신념 수준이 낮았으며 A형 간염 예방접종률 또한 낮았다. 따라서 적절한 보건교육을 통해 지식을 습득할 수 있게 하고, 질병 예방행위 실천 및 A형 간염 예방접종률을 높일 수 있는 방안들이 모색될 필요가 있을 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제32권6호
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• pp.792-799
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• 2019

Objective: This study was conducted to evaluate whether the co-injection of antioxidants together with foot-and-mouth disease (FMD) vaccination has the potential to attenuate the negative effects caused by vaccination in Holstein finishing steers. Methods: A total of 36 finishing Holstein steers (body weight [BW]: $608{\pm}45.6kg$, 17 months old) were randomly allocated to one of three treatments: i) control (CON, only FMD vaccination without any co-injection), ii) co-injection of commercial non-steroidal anti-inflammatory drugs (NSAID) with FMD vaccination at a ratio of 10:1 (NSAID vol/FMD vaccine vol) as a positive control (PCON), iii) co-injection of commercial mixture of vitamin E and selenium with FMD vaccination (VITESEL) (1 mL of FMD vaccine+1 mL of antioxidants per 90 kg of BW). Changes in growth performance and blood parameters because of treatments were determined. Results: No significant difference in BW, average daily gain, and dry matter intake of the steers was observed among the treatments. The FMD vaccination significantly increased white blood cells (WBC), neutrophils, platelets, and mean platelet volume (p<0.01) in blood analysis. The count of lymphocyte tended to increase after vaccination (p = 0.08). In blood analysis, steers in VITESEL tended to have higher numbers of WBC, neutrophils, and platelets compared to that of other treatments (p = 0.09, 0.06, and 0.09, respectively). Eosinophils in VITESEL were higher than those in PCON (p<0.01). Among blood metabolites, blood urea nitrogen and aspartate transaminase were significantly increased, but cholesterol, alanine transferase, inorganic phosphorus, Mg, and albumin were decreased after FMD vaccination (p<0.01). Conclusion: The use of antioxidants in FMD vaccination did not attenuate growth disturbance because of FMD vaccination. The metabolic changes induced by vaccination were not controlled by the administration of antioxidants. The protective function of antioxidants was effective mainly on the cell counts of leukocytes.

• 종양간호연구
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• 제11권3호
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• pp.193-199
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• 2011

Purpose: This study was aimed to examine mothers'knowledge about human papillomavirus (HPV)vaccination to prevent cervical cancer in Korea. Methods: From September 20 to October 10 2011, 101 mothers who have adolescent girls were surveyed with questionnaires about their general characteristics, the knowledge of HPV vaccine, inoculation rate and vaccination-related factors of their daughters. Results: The percentage of correct answers for HPV vaccine knowledge was 24.2% and the HPV vaccination rate was only 5.9%. HPV vaccine knowledge score of the vaccination group was significantly higher than that of the non-vaccinated group. Mothers said that the reasons why they didn't vaccinate their daughters against the HPV was the financial burden, the lack of HPV knowledge, and worries about possible side effects. The participants addressed that they understood the appropriate age for vaccination was sixteen. Conclusion: We recommend that more educational and promotional efforts need to be given for mothers in order to improve their knowledge of HPV vaccination and to increase the performance rates of HPV immunization against cervical cancer for their daughters.

• Journal of Microbiology and Biotechnology
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• 제31권12호
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• pp.1601-1614
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• 2021

To overcome the ongoing COVID-19 pandemic, vaccination campaigns are the highest priority of majority of countries. Limited supply and worldwide disproportionate availability issues for the approved vaccines, together with concerns about rare side-effects have recently initiated the switch to heterologous vaccination, commonly known as mixing of vaccines. The COVID-19 vaccines are highly effective in the general population. However, none of the vaccines is 100% efficacious or effective, with variants posing more challenges, resulting in breakthrough cases. This review summarizes the current knowledge of immune responses to variants of concern (VOC) and breakthrough infections. Furthermore, we discuss the scope of heterologous vaccination and future strategies to tackle the COVID-19 pandemic, including fractionation of vaccine doses and alternative route of vaccination.