• Title/Summary/Keyword: VTA

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Estimation of Strength Loss and Decay Severity of Juniperus procera by Juniper Pocket Rots Fungus, P. demidoffii in Ethiopian Forests

  • Assefa, Addisu
    • Journal of Forest and Environmental Science
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    • v.36 no.2
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    • pp.143-155
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    • 2020
  • A juniper pocket rot fungus, Pyrofomes demidoffii is a basidiomycetous fungus responsible for damage of living Juniperus spp. However, its effect on the residual strength and on the extent of decay of juniper's trunk was not determined in any prior studies. The purpose of this study was to study the features of J. procera infected by P. demdoffii, and to estimate the level of strength loss and decay severity in the trunk at D.B.H height using different five formulas. Infected juniper stands were examined in two Ethiopian forests through Visual Tree Assessment (VTA) followed by a slight destructive drilling of the trunk at D.B.H height. The decayed juniper tree is characterized by partially degraded lignin material at incipient stage of decay to completely degraded lignin material at final stage of decay. In the evaluated formulas, results of ANOVA showed that a significantly higher mean percentage of strength loss and decay severity were recorded in the trees of larger D.B.H categories (p<0.001). The strength loss formulas produced the same to similar patterns of sum of ranks of strength loss or decay severity in the trunk, but the differences varied significantly among D.B.H categories in Kruskal Wallis-test (p<0.001). In conclusion, the employed formulas showed similar to different degree of variability in quantification of strength loss or decay severity in the trunk. The findings of our study could be used as the baseline for further study on juniper's strength loss or decays in the trunk of Juniperus spp. and unequivocally helps to design the corresponding management as result of P. demidoffii.

Prediction of the Effective Wake of an Axisymmetric Body (축대칭 몰수체의 유효반류 추정)

  • Kim, Ki-Sup;Moon, Il-Sung;Ahn, Jong-Woo;Kim, Gun-Do;Park, Young-Ha;Lee, Chang-Sup
    • Journal of the Society of Naval Architects of Korea
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    • v.56 no.5
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    • pp.410-417
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    • 2019
  • An axisymmetric submerged body(L=5.6m, Diam=0.53m) is installed in Large Cavitation Tunnel (LCT) of KRISO and the nominal and total velocities without and with the propeller in operation, respectively, are measured using Laser Doppler Velocimeter (LDV). The flow field is nearly axisymmetric except the wake of the supporting strut, and is considered ideal to study the hydrodynamic interaction between the propeller and the oncoming axisymmetric sheared flow. The measured velocity data are then provided to compute the propeller-induced velocity to get the effective velocity, which is defined by subtracting the propeller-induced velocity from the total velocity. We adopted, in computing the induced velocity, two different methods including the vortex lattice method and the vortex tube actuator model to evaluate the resultant effective velocity distribution. To secure a fundamental base of experimental data necessary for the research on the effective wake, we measured the drag of the submerged body, the nominal and total velocity distributions at various axial locations for three different tunnel water speeds.

Effects of Mixture of Citri Peticulatae Viride Pericarpium and Lycii Radicis Cortex on the Change of HPA-Axis and Catecholamic System in the Forced Swimming Test (청피(靑皮)와 지골피(地骨皮) 복합제(複合劑)가 강제수영부하실험에서 CRF, c-Fos와 TH의 변화에 미치는 영향)

  • Park, Soo-Hyun;Lee, Tae-Hee
    • The Korea Journal of Herbology
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    • v.25 no.2
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    • pp.117-128
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    • 2010
  • Objectives : In this study the antidepressant effects of mixture of Citri Peticulatae Viride Pericarpium and Lycii Radicis Cortex on the change of HPA-Axis and Catecholamic system was investigated Methods : The forced swimming test(FST) was performed. The expression of corticotropin-releasing factor(CRF), c-Fos in the paraventricular nucleus(PVN), and tyrosine hydroxylase(TH) in the ventral tegmental area(VTA) and locus coeruleus(LC) was measured with immunohistochemical method and the concentration of seum adrenocorticotropic hormone(ACTH) was measured with ELISA method. And the experimental groups were divided into the extraction after mixing(A) and mixture after extraction(B). The effects of both group were compared. Results : The duration of immobility in the forced swimming test was significantly decreased in the A400 group(P<0.01). The expression of CRF in PVN were significantly reduced in the A100, A400, B100, B400groups(P<0.001). but the expression of c-fos in PVN weren't reduced in all groups. And the concentration of ACTH in Plasma were significantly reduced in the A 100 group(P<0.01). The expression of TH in LC were significantly reduced in the A 400, B 100 and B400 groups(P<0.05~P<0.01). Conclusion : Mixture of Citri Peticulatae Viride Pericarpium and Lycii Radicis Cortex has antidepressant effects. But the difference between mixing and extracting methods was not shown.

Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats

  • Zhao, ZhengLin;Kim, Young Woo;Wu, YiYan;Zhang, Jie;Lee, Ju-Hee;Li, XiaoHua;Cho, Il Je;Park, Sang Mi;Jung, Dae Hwa;Yang, Chae Ha;Kim, Sang Chan;Zhao, RongJie
    • Journal of Ginseng Research
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    • v.38 no.4
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    • pp.256-263
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    • 2014
  • Background: Korean Red Ginseng (KRG) is known to have antianxiety properties. This study was conducted to investigate the anxiolytic effects of KRG extract (KRGE) during ethanol withdrawal (EW) and the involvement of the mesoamygdaloid dopamine (DA) system in it. Methods: Rats were treated with 3 g/kg/d of ethanol for 28 d, and subjected to 3 d of withdrawal. During EW, KRGE (20 mg/kg/d or 60 mg/kg/d, p.o.) was given to rats once/d for 3 d. Thirty min after the final dose of KRGE, anxiety-like behavior was evaluated in an elevated plus maze (EPM), and plasma corticosterone (CORT) levels were determined by a radioimmunoassay (RIA). In addition, concentrations of DA and 3,4-dihydroxyphenylacetic acid (DOPAC) in the central nucleus of the amygdala (CeA) were also measured by high performance liquid chromatography (HPLC). Results: The EPM test and RIA revealed KRGE inhibited anxiety-like behavior and the over secretion of plasma CORT during EW. Furthermore, the behavioral effect was blocked by a selective DA D2 receptor (D2R) antagonist (eticlopride) but not by a selective DA D1 receptor (D1R) antagonist (SCH23390). HPLC analyses showed KRGE reversed EW-induced decreases of DA and DOPAC in a dose-dependent way. Additionally, Western blotting and real-time polymerase chain reaction (PCR) assays showed that KRGE prevented the EW-induced reductions in tyrosine hydroxylase (TH) protein expression in the CeA and TH mRNA expression in the ventral tegmental area (VTA). Conclusion: These results suggest that KRGE has anxiolytic effects during EW by improving the mesoamygdaloid DA system.

Assessment of physical condition of old large Chionanthus retusus(Chinese Fringe Tree) using structural stability analysis (천연기념물 이팝나무 노거수 구조안정성 진단을 통한 물리적 생육상태 평가)

  • SON Jiwon;SHIN Jinho
    • Korean Journal of Heritage: History & Science
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    • v.56 no.1
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    • pp.118-130
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    • 2023
  • Decay or large cavities inside trees are the main causes of trees overturning and broken branches, and structurally weakened trees are more vulnerable to strong winds and heavy snowfall. Recently, as strong winds and typhoons increase due to climate change, the damage to human life and property due to trees overturning continues to increase, and cultural assets are in a similar situation. In particular, old big trees are structurally vulnerable to external shocks such as strong winds and heavy snowfall. This study was aimed at providing a scientific basis for preventive protection measures by conducting a structural stability diagnosis of seven retusa fringe trees designated as natural monuments. For the structural stability diagnosis, tree risk assessment and internal tree defect measurements were performed. As a result of the tree risk assessment, the Retusa Fringe Trees in Sinjeon-ri, Yangsan and Gwangyangeupsu had the highest risk of broken branches due to weak branch attachment strength. As a result of the diagnosis of internal defects of cross sections of measured trees, there were suspected cavities or severe decay in all except two trees of the population of Retusa Fringe Trees in Pyeongji-ri. Natural disasters due to climate change are increasing, and the scale is getting larger, so it is very important to preemptively manage large old trees through scientific structural safety diagnosis to manage trees that are vulnerable to environmental changes.

Effect of Ondansetron Alone and Combination of Naltrexone and Ondansetron on Alcohol Intake in C57BL/6 Mice (Naltrexone과 ondansetron의 병합투여가 C57BL/6형 생쥐의 알코올 섭취량에 미치는 영향)

  • Kim, Hyeun-Kyeung;Kim, Sung-Gon;Kang, Cheol-Joong;Park, Sang-Ick;Kim, Won-Ho
    • Journal of Life Science
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    • v.17 no.11
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    • pp.1576-1581
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    • 2007
  • Dopamine reward pathway projecting from ventral tegmental area to nucleus accumbens is well known as playing an important role in alcohol dependence. It is supposed that this dopamine pathway is modulated by $5-HT_3$ nervous system, and it was reported that ondansetron (OND), $5-HT_3$ receptor antagonist, reduced drinking amount and increased abstinence rate in alcohol-dependent patients. The purpose of this study is to investigate the effect of combination of OND and naltrexone (NTX), non-specific opioid receptor antagonist, on alcohol intake in C57BL/6 mice. In 40 C57BL/6 mice in the state of alcohol dependence, vehicle, while OND 0.01 mg/kg, or NTX 1.0 mg/kg administrated respectively, or OND 0.01 mg/kg and NTX 1.0 mg/kg administrated simultaneously for ten days, medication effects on 2-hr alcohol, 22-hr water, 24-hr food intake and body weight were studied. When vehicle group was compared with 3 medication groups respectively, using a repeated measure ANOVA, NTX alone and vehicle groups showed a significant medication by time interaction (p=0.042) in 2-hr alcohol intake, but in the other 2 groups, OND and NTX combination group and OND alone group, there was no significant interaction with vehicle group in 2-hr alcohol intake. From these results, it is suggested that there is no effect on alcohol intake in mice treating with OND, and naltrexone#s suppression effect on alcohol intake in mice is attenuated when treating with OND and NTX simultaneously. It is supposed that a further study looking at the interactions of serotonin, dopamine and opioid nerves systems will be needed.