• 지질공학
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• 제31권2호
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• pp.211-222
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• 2021

포항지진은 2017년 규모 5.4의 포항시 북구 북쪽 7.5 km 부근에서 발생하였다. 지진피해가 크게 발생한 경상북도 포항 북구 지역의 상시미동의 특성을 알아보기 위하여 총 39 지점에 상시미동 자료를 취득하여 수평 대 수직 스펙트럼 비율(Horizontal to Vertical Spectral Ratios, HVSR) 분석연구를 실시하였다. 상시미동은 지역에 따라 각각 다르므로 상시미동을 조사해 그 지역의 공명주파수를 취득한다. 층후 분석을 위해서는 기반암까지의 전단파 속도(Vs) 구조 및 특성을 분석하여 공명주파수를 인근의 시추자료와 대비하여 수평 대 수직 스펙트럼 비율(Horizontal to Vertical Spectral Ratios, HVSR) 분석기법이 일치하는지 비교하였다. 충적층의 공명주파수 1.3 ± 0.07 Hz, 연일층군의 공명주파수 0.69 ± 0.22 Hz로 F₀ = V_s/4H를 이용하여 층후를 구하면 충적층은 26~30 m, 연일층군은 170~250 m로 인근 시추자료와 비교하여 대체로 일치한 것으로 분석하였다.

• Tuberculosis and Respiratory Diseases
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• 제86권3호
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• pp.234-244
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• 2023

Background: Effective treatment of fluoroquinolone-resistant multidrug-resistant tuberculosis (FQr-MDR-TB) is difficult because of the limited number of available core anti-TB drugs and high rates of resistance to anti-TB drugs other than FQs. However, few studies have examined anti-TB drugs that are effective in treating patients with FQr-MDR-TB in a real-world setting. Methods: The impact of anti-TB drug use on treatment outcomes in patients with pulmonary FQr-MDR-TB was retrospectively evaluated using a nationwide integrated TB database (Korean Tuberculosis and Post-Tuberculosis). Data from 2011 to 2017 were included. Results: The study population consisted of 1,082 patients with FQr-MDR-TB. The overall treatment outcomes were as follows: treatment success (69.7%), death (13.7%), lost to follow-up or not evaluated (12.8%), and treatment failure (3.9%). On a propensity-score-matched multivariate logistic regression analysis, the use of bedaquiline (BDQ), linezolid (LZD), levofloxacin (LFX), cycloserine (CS), ethambutol (EMB), pyrazinamide, kanamycin (KM), prothionamide (PTO), and para-aminosalicylic acid against susceptible strains increased the treatment success rate (vs. unfavorable outcomes). The use of LFX, CS, EMB, and PTO against susceptible strains decreased the mortality (vs. treatment success). Conclusion: A therapeutic regimen guided by drug-susceptibility testing can improve the treatment of patients with pulmonary FQr-MDR-TB. In addition to core anti-TB drugs, such as BDQ and LZD, treatment of susceptible strains with later-generation FQs and KM may be beneficial for FQr-MDR-TB patients with limited treatment options.

• International Journal of Railway
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• 제5권3호
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• pp.103-113
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• 2012

Infrastructure costs could be greatly reduced if the need for bridges and tunnels was reduced, or if the line could be shortened. Tilting trains might be a less costly alternative to building new tracks with large curve radii, because tilting trains can negotiate tighter curves without having to decrease their speeds. Tracks built for tilting trains would be cheaper, as they require fewer bridges and tunnels. This paper compares the construction costs of two different options for the new Dodam-Yeoncheong section on the Central line, which includes 148.65 km of new electrified double-track with a design speed of 250 km/h. The first option is to straighten the high-speed line. The second option is to build a line with small radii curves and run tilting trains on the line. In the first option, tunnels would account for about 51% of the new section. In comparison, the second option would have shorter curves and fewer tunnels and bridges which would reduce construction costs. Furthermore, alignment modifications could be made to several segments on the straight line, making the most of the existing roadbed. The analysis concluded that the line suited to tilting trains would be 95.7 million USD cheaper to build the straight route. That is a savings of 2.8% of the total project cost. However, this option would increase the total travel time of the route by 1.2 minutes, which means it is not necessarily the best choice.

• Clinical Endoscopy
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• 제56권2호
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• pp.169-179
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• 2023

Background/Aims: This meta-analysis analyzed the effect of an indwelling biliary stent on endoscopic ultrasound (EUS)-guided tissue acquisition from pancreatic lesions. Methods: A literature search was performed to identify studies published between 2000 and July 2022 comparing the diagnostic outcomes of EUS-tissue acquisition (TA) in patients with or without biliary stents. For non-strict criteria, samples reported as malignant or suspicious for malignancy were included, whereas for strict criteria, only samples reported as malignant were included in the analysis. Results: Nine studies were included in this analysis. The odds of an accurate diagnosis were significantly lower in patients with indwelling stents using both non-strict (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.52-0.90) and strict criteria (OR, 0.58; 95% CI, 0.46-0.74). The pooled sensitivity with and without stents were similar (87% vs. 91%) using non-strict criteria. However, patients with stents had a lower pooled sensitivity (79% vs. 88%) when using strict criteria. The sample inadequacy rate was comparable between groups (OR, 1.12; 95% CI, 0.76-1.65). The diagnostic accuracy and sample inadequacy were comparable between plastic and metal biliary stents. Conclusions: The presence of a biliary stent may negatively affect the diagnostic outcome of EUS-TA for pancreatic lesions.

• 자원환경지질
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• 제28권6호
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• pp.635-646
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• 1995

동양활석광상의 광화대는 옥천누층군에 속하는 향산리 돌로마이트의 최하부 돌로마이트층준에 발달하며 광체는 이 지역 지층 중에 밥달하는 $N85^{\circ}{\sim}90^{\circ}W$에 $40^{\circ}$ 로 플란지하는 작은 습곡축에 따라 파이프상으로 배태되어 있다. 이 광상의 모든 광체들의 상반이나 하반에 각섬질암이나 녹니석편암을 수반한다(김옥준 등, 1963; 박희인과 김기태, 1966). 동양활석광상의 활석광화작용은 돌로마이트의 재결정작용과 규화작용에 이어 투각섬석과, 판상, 엽편상활석(I), 미립질 활석 (II)의 생성 순으로 이루어졌다. 활석(I)은 돌로마이트와 $SiO_2$ 성분이 풍부한 유체와의 반응으로 생성되었고 활석 (II)는 돌로마이트와 유세와의 반응과 이마 생성된 투각섬석과 유체와의 반응으로 생성되었다. 광화기간중 유체는 초기에는 $H_2O-CO_2$계의 것으로 $CO_2$가 풍부한 것이었으나, 말기로 가며 $H_2O-NaCl-CO_2 $계를 거쳐 $H_2O-NaCl $계의 것으로 변하였다. 투각섬석과 활석(l) 생성기의 온도 및 압력조건은 각각 1,640~2,530 bar, $440{\sim}480^{\circ}C$ 였고, 활석 (II) 생성기의 온도 및 압력조건은 1,400~2,200 bar와 $360{\sim}390^{\circ}C$였다. 이 값은 동양활석광상 북쪽 약 5km에 분포하는 문주리층 구성암석의 변성온도 및 압력값에 비하여 현저하게 낮다. 활석광상의 모암인 돌로마이트의 ${\delta}^{13}C$과 ${\delta}^{18}O$값은 각각 2.9~5.7‰ (PDB)과 -7.4~16.8‰ (PDB)로서 기 보고된 태백산지역의 석회암의 값에 비하여 높으나 변질받지 않은 퇴적원 돌로마이트가 갖는 값의 범위내에 든다. 동양활석광상의 활석의${\delta}^{18}O$와 ${\delta}D$값은 각각 +8.6-15.8‰ (vs SMOW)와 -65~-90‰ (vs SMOW)로서 마그마 기원의 물의 값을 갖는다. 이 값은 이 지역의 문주리층과 계명산층을 구성하는 변성암류의 ${\delta}^{18}O$과 ${\delta}D$ 값과는 판이하다. 경석고의 ${\delta}^{34}S$ 값은 22.4‰ (CDT)로서 고생대초의 황산염의 ${\delta}^{34}S$의 값(30‰ vs CDT)보다 낮아 화성기원의 S가 첨가되었을 가능성이 있다. 활석광석에는 약하게 염리와 파랑벽개 등이 발달하고 있어 활석광상은 옥천대가 겪은 여러 차례의 변형작용중 최후기상이 적어도 끝나가 이전에 마그마 기원의 유체에 의하여 생성된 열수교대 광상이라 사료된다.

• 화약ㆍ발파
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• 제20권3호
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• pp.49-58
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• 2002

발파공법이 소개된 이후로 계속해서 많은 우수한 발파이론이 발표되어 왔다. 그러한 이론들의 저변에 있는 궁극적인 목표는 효율의 증가와 경제성이다. 이에 본 연구는 Air-Tubes 발파공법을 소개하고 터널에서 일반발파와 비교하여 그 발파효율을 검토해 보았다 연구의 배경이 되는 곳은 산청군 시천면 내대리와 하동관 묵계리를 연결하는 2차선 국도 터널 공사 현장이며 전체 총연장은 2Km이다. 진동측정방법은 하나의 발파진동을 4개의 측정기로 측정하여 데이터분석에 사용하였다. 일반발파와 Air-Tubes의 진동측정을 4개소에서 각각 6회씩 실시하여 총 24개씩의 진동측정 데이타를 얻었고 회귀분석을 실시하여 95% 신뢰도의 발파진동 추정식을 얻었다. 시험발파 및 진동측정에 이어 매 발파마다 광파측량을 실시하여 진행장을 구하였으며 사용한 장약량은 Air-Tubes 발파시 25% 정도 적게 사용하였고 발파진동이 23% 감소하였다. 발파당 굴진장 및 Smooth blasting 발파시의 벽면의 상태는 동일하고 파쇄석의 크기는 Air-Tubes 발파시 더 작게 나타난다.

• Safety and Health at Work
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• 제8권1호
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• pp.36-41
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• 2017

Background: Police work is generally sedentary although there may be situations that require physical endurance and strength, such as foot chases and arresting suspects. Factors such as excessive body fat can impede an officer's physical ability to deal with such occurrences. Our objective was to examine associations between officers' body fat percentage (BF%) and performance on a standardized fitness protocol. Methods: Data were obtained from fitness screening among 1,826 male and 115 female officers in a large US police agency. The screening consisted of a 2.4-km run, push-ups, sit-ups, and sit-and-reach test. Sex-specific body fat percentages were estimated from skinfold thickness measured using calipers. Linear regression models were used to examine unadjusted and adjusted mean scores of fitness tests across BF% tertiles. Results: The prevalence of overall fitness was 4.3 times greater in male officers and 3.6 times greater in female officers having the lowest BF% tertile compared with the highest tertile (30.3% vs 7.1% and 46.0% vs 12.8%, respectively). BF% was linearly and positively associated with the time of 2.4-km run (p < 0.001), and linearly and inversely associated with the number of push-ups (p < 0.001), sit-ups (p < 0.001), and the distance of sit-and-reach (p < 0.001) in men. Similar associations were observed in women with the exception of sit-and-reach (p = 0.122). Associations were independent of age, race/ethnicity, rank, and duty station. Conclusion: Overall, BF% was inversely associated with fitness levels in male and female officers. Future longitudinal studies should be initiated to explore the potentially causal relationship between BF% and fitness in law enforcement officers.

• 한국미생물·생명공학회지
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• 제17권1호
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• pp.29-34
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• 1989

고도 카드뮴 내성 효모, Hansenula anomala B-7 의 intact cell에 의한 카드뮴의 세포내 축적에 미치는 계면활성제의 영향를 검토하고, Triton X-100의 존재하에서의 카드뮴 축적에 미치는 제인자 등을 검토했다. 카드뮴의 축적은 0.1% Triton X-100과 Aerosol OT에 의하여 약 40% 이상 증가되었다. 카드뮴 이온에 대한 Km값은 0.247mM로 계산되었다. 카드뮴의 축적 최적 pH는 pH7.0에서 pH10.0 사이였으며, 최적온도는 4$0^{\circ}C$였다. 카드뮴의 최적 축적은 정치보다 진탕하므로 약 3배 증가되었으며, 진탕속도는 영향을 미치지 않았다. 카드뮴과 아연 이온을 공존시키므로 카드뮴의 축적이 아연 이온에 의하여 저해되었다.

• 한국도로학회논문집
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• 제14권6호
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• pp.131-138
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• 2012

PURPOSES : Two-lane highways have one lane in each direction, and lane changing and passing maneuvers take place in the opposing lane depending on the availability of passing sight distance. 2001 Korea Highway Capacity Manual (KHCM) is classified into two classes of two-lane highways (Type I, II), and average travel speed and time-delayed rate are used as measures of effectiveness (MOEs). However, since existing two-lane highways have both uninterrupted and interrupted traffic flow-system elements, a variety of free-flow speeds exhibits in two-lane highways. In addition, it is necessary to check if the linear-relationship between volumes and time-delayed rate is appropriate. Then, this study is to reestablish the relationship between average travel speed, time-delayed rate, and flow. METHODS : TWOPAS model was selected to conduct this study, and the free-flow speeds of passenger cars and the percentage of following vehicles observed in two-lane highways were applied to the model as the input. The revised relationships were developed from the computer simulation. RESULTS : In the revised average travel speed vs. flow relationship, the free-flow speed of 90km/h and 70km/h were added. It shows that the relationship between time delayed-rate and flow appeared to be appropriate with the log-function form and that there was no difference in time-delayed rate between the free flow speeds. In addition to revise the relationships, the speed prediction model and the time-delayed rate prediction model were also developed. CONCLUSIONS : The revised relationships between average travel speed, time-delayed rate, and flow would be useful in estimating the Level of Service(LOS) of a two-lane highway.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2001년도 춘계학술발표논문집
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• pp.18-25
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• 2001

A new wood-degrading fungus Trichophyton rubrum LKY-7 secretes a high level of laccase in a glucose-peptone liquid medium. The production of laccase by the fungus was barely induced by 2,5-xylidine. The laccase has been purified to homogeneity through three chromatography steps in an overall yield of 40%. The molecular mass of the purified laccase was about 65 kDa by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The purified laccase had the distinct blue color and had basic spectroscopic features of a typical blue laccase: two absorption maxima at 278 and 610 nm and a shoulder at 338 nm. The N-terminus of the laccase has been sequenced, revealing high homology to laccases from wood-degrading white-rot fungi such as Ceriporiopsis subvermispora. The enzyme had a "low" redox potential (0.5 V vs normal hydrogen electrode), yet it was one of the most active laccases in oxidizing a series of representative substrates/mediators. Compared with other fungal laccases, the laccase has a very low Km value with ABTS [2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid] as a substrate and a very high Km value with violuric acid as a substrate. The laccase has the isoelectric point of 4.0. The laccase had very acidic optimal pH values (pH 3-4) while it was more stable at neutral pH than at acidic pH. The laccase oxidized hydroquinone faster than catechol and pyrogallol. The oxidation of tyrosine by the laccase was not detectable under the reaction conditions. The laccase was strongly inhibited by sodium azide and sodium fluoride. fluoride.