• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9679-9685
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• 2014

Background: When evaluating health-economics for cervical cancer prevention policies in Japan, it is important to use Japanese value settings. This study aimed to obtain preference-based measures (preference measures) for hypothesized health states among healthy Japanese women, and to examine differences between the EuroQol-5D (EQ-5D) and standard gamble (SG) instruments. Materials and Methods: The investigation was performed among female students at a nursing university. We used written hypothetical scenarios describing three grades of cervical intraepithelial neoplasia (CIN) and eight stages of cervical cancer, both at diagnosis and after medical intervention. Preference measures were evaluated using both EQ-5D and SG. Results: We received responses from 136 women. The mean number of respondents per stage was 24.6 (SD: 2.7). At diagnosis, average EQ-5D scores for CIN1, CIN2, CIN3, IA1, IA2, IB1, IB2, IIA, IIB, III, and IV stages were 0.84 (0.14), 0.78 (0.12), 0.73 (0.10), 0.78 (0.12), 0.72 (0.12), 0.63 (0.13), 0.64 (0.12), 0.68 (0.08), 0.62 (0.13), 0.55 (0.21), and 0.18 (0.24), respectively. Using one-way analysis of variance with the Tukey-Kramer method for multiple comparisons (each stage vs. CIN1), we found significant differences for IB1 and more advanced stages (p<0.05). After medical intervention, corresponding EQ-5D scores were 0.84 (0.12), 0.81 (0.12), 0.84 (0.12), 0.80 (0.15), 0.78 (0.11), 0.64 (0.15), 0.63 (0.15), 0.71 (0.15), 0.50 (0.17), 0.52 (0.17), 0.21 (0.28). The multiple comparisons identified significant differences for IB1 and more advanced stages, excepting IIA (p<0.05). SG evaluations were more variable and relatively higher than EQ-5D evaluations. Conclusions: We obtained preference measures for three grades of CIN1-3 and eight stages of cervical cancer. In combination with appropriate sensitivity analyses, these preference measures will provide a basis for an economic evaluation of cervical cancer prevention in Japan. We suggest that EQ-5D is appropriate for cost-utility analysis of this topic.

• Journal of Korean Ophthalmic Optics Society
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• v.2 no.1
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• pp.111-126
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• 1997

I concluded as follows after analyzing the problem of the curriculum in the Department of Optical Science at a college of professional education for the purpose of training desireable opticians. The years required for competing a course of study at the Department of Optical Science at a college of professonal education have to be extended from the present two school years to three years for the short run and have to be extended to four years for the long run. The distribution ratio of subjects in the slate examination should be readjusted and the field of contect lens. Also the system of the slate examination should strengthen by adding practical processing test with the present selective written examination. The Curriculum of department of Optical Science curriculum at a college of professional education should be reorganized reinforce experiment and practice, namely, the subject for experiment and practice, such as Making of specific glasses and Test method of phorpter etc, should be reinforced. The knowledge for goods should be included in clinical training and it is reasonable to constitute the theory vs the practice in the ratio of five to five. The number of the Department of Optical Science should be increased two or more for per forty students and it is desirabled that only the professors who major optical Science or opthalmic medical science, or have Optician Licence should give lecture. The experiment a practice should be enlarged and it is necessary to secure or to adopt practice hours, practice site, machinery and parts, practice assistant and etc. It is reasonable that clinical training include the knowledge of goods, business practice and etc. and that a practice examiner has the qualification as an optician who has education background higher that the college of professional education.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.362-373
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• 2018

This study was conducted to investigate the relationship between interest in smoking cessation and factors that define this interest. The study subjects were 593 male civil servants who work at D metropolitan city and were smokers at the time of the survey. The research method was a survey using a self-administered questionnaire in October 2015. Interest in smoking cessation of study subjects showed that 28.3% had no interest in smoking cessation, 45.7% were interested in smoking cessation, but had no intention to quit within six months, and 26.0% were interested in smoking cessation and intended to quit within six months. Multiple regression analysis revealed that the factors influencing interest in smoking cessation with explanatory powers of 23.6% were employment type, age when first starting smoking, number of cigarettes smoked per day, time from when you wake up until you smoke your first cigarette, recognition of susceptibility to lung cancer, and benefits to smoking cessation. Logistic regression analysis revealed that the odds ratio of recognition of susceptibility for lung cancer, benefits to smoking cessation, and barriers to smoking cessation were significantly increased in the group with interest in smoking cessation and intention to quit within six months vs. the group with no interest in smoking cessation. Taken together, these results suggest that cancer prevention due to smoking and awareness of the seriousness of health problems caused by smoking were factors increasing interest in smoking cessation.

• Journal of Aerospace System Engineering
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• v.12 no.4
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• pp.64-74
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• 2018

Small high-resolution Earth observation satellites require precise optical alignment at the submicron level. However, misalignments can occur due to the influence of external factors during the launch and operation despite the sufficient alignment processes that take place before the launch. Thus, satellites need to realign their optical elements in orbit in what is known as a refocusing process to compensate for any misalignments. Refocusing algorithms developed for satellites have only considered de-space, which is the most sensitive factor with respect to image quality. However, the existing algorithms can cause correction error when inner and external forces generate tilt amount in an optical system. The present work suggests an improved online refocusing algorithm by considering the tilting effect for application in the case of a de-spaced and tilted optical system. In addition, the algorithm is considered to be efficient in terms of time and cost because it is designed to be used as an online method that does not require ground communication.

• Radiation Oncology Journal
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• v.32 no.3
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• pp.198-207
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• 2014

Purpose: To evaluate the effects of total body irradiation (TBI), as a conditioning regimen prior to allogeneic stem cell transplantation (allo-SCT), in pediatric acute leukemia patients. Materials and Methods: From January 2001 to December 2011, 28 patients, aged less than 18 years, were treated with TBI-based conditioning for allo-SCT in our institution. Of the 28 patients, 21 patients were diagnosed with acute lymphoblastic leukemia (ALL, 75%) and 7 were diagnosed with acute myeloid leukemia (AML, 25%). TBI was completed 4 days or 1 day before stem cell infusion. Patients underwent radiation therapy with bilateral parallel opposing fields and 6-MV X-rays. The Kaplan-Meier method was used to calculate survival outcomes. Results: The 2-year event-free survival and overall survival rates were 66% and 56%, respectively (71.4% and 60.0% in AML patients vs. 64.3% and 52.4% in ALL patients, respectively). Treatment related mortality rate were 25%. Acute and chronic graft-versus-host disease was a major complication; other complications included endocrine dysfunction and pulmonary complications. Common complications from TBI were nausea (89%) and cataracts (7.1%). Conclusion: The efficacy and toxicity data in this study of TBI-based conditioning to pediatric acute leukemia patients were comparable with previous studies. However, clinicians need to focus on the acute and chronic complications related to allo-SCT.

• Journal of Global Scholars of Marketing Science
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• v.16 no.3
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• pp.39-60
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• 2006

The purpose of this study is to investigate the effect of two different characteristics of music(tempo) and advertising photograph(type) in a fashion store on consumers' emotional responses and approach behavior and to suggest competitive in-store atmospheric strategies. To test the conceptual model, this study used a video simulation method. Researchers selected a fashion casual wear retail store for young people and videotaped to provide realistic store settings. Two different levels of background music(fast, slow) and advertising photograph(sexy, cheerful) were inserted into the video clip generating four stimuli. Including a stimulus for the control group, 5 video clips were created. A total of 289 subjects answered the questionnaire after viewing a two-minute video clips. The results are as follows: First, advertising photograph in a store had a significant effect on consumers' in-store emotional state, whereas musical tempo did not. Second, the effect of in-store consumers' emotional state on behavioral reponses were investigated. Results showed that consumers' positive emotional state lead to consumers' approach behavior. The results of this study indicated that background music and advertising photograph in a fashion store affected consumers' in-store emotional state, and ultimately these affected consumers' positive approach behavior. Thus retailer should try to create a pleasant store environment using effective store atmospheric factors like background music and advertising photograph.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.551-557
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• 2015

Background: Differentiating morphologic features based on hematoxylin-eosin (HE) staining is the most common method to classify pathological subtypes of non-small-cell lung cancer (NSCLC). However, its accuracy and inter-observer reproducibility in pathological diagnosis of poorly differentiated NSCLC remained to be improved. Materials and Methods: We attempted to explore the role of immunohistochemistry (IHC) staining in diagnosing pulmonary squamous cell carcinoma (SQCC) with poorly differentiated features by HE staining or with elevated serum adenocarcinoma-specific tumor markers (AD-TMs). We also compared the difference of epidermal growth factor receptor (EGFR) mutation rate between patients with confirmed SQCC and those with revised pathological subtype. Logistic regression analyses were used to test the association between different factors and diagnostic accuracy. Results: A total of 132 patients who met the eligible criteria and had adequate specimens for IHC confirmation were included. Pathological revised cases in poor differentiated subgroup, biopsy samples and high-level AD-TMs cases were more than those with high/moderate differentiation, surgical specimens and normal-level AD-TMs. Moreover, biopsy sample was a significant factor decreasing diagnostic accuracy of pathological subtype (OR, 4.037; 95% CI 1.446-11.267, p=0.008). Additionally, EGFR mutation rate was higher in patients with pathological diagnostic changes than those with confirmed SQCC (16.7% vs 4.4%, p=0.157). Conclusions: Diagnosis based on HE staining only might cause pathological misinterpretation in NSCLC patients with poor differentiation or high-level AD-TMs, especially those with biopsy samples. HE staining and IHC should be combined as pathological diagnostic standard. The occurrence of EGFR mutations in pulmonary SQCC might be overestimated.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.1
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• pp.89-99
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• 2018

The number of traffic accidents in Korea has been increasing since 2014. In most school zones, safety signs are installed to prevent children's traffic accidents. However, it has been known that the effects of those signs are not significant. A variable message sign(VMS), one of the components of Intelligent Transport System(ITS), has emerged as an alternative method. Therefore, this study examines relative effects of two different VMS messages(Timely vs. Continuous) on vehicle speed. Experiments were conducted in two school zones. 6,676 vehicles were measured for speed limit compliance. A counterbalanced multiple baseline design was adopted. The results showed that both types of message are effective in reducing the speed of vehicle. Specifically, A timely message was more effective in slowing down vehicle speed and improving speed limit compliance than a continuous message. The present study suggested that a VMS with human factors can be effective.

• The Korean Journal of Emergency Medical Services
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• v.15 no.2
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• pp.101-108
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• 2011

Purpose: Cardiopulmonary resuscitation (CPR) prevents tissue necrosis of the brain and cardiac muscle in the cardiac arrest patient and requires exact skills in order to increase survival rate. Through comparison of the training effects of feedback manikin and non-feedback manikin, this study present the effective CPR device to CPR instructors. Method: This CPR course for 80 students by using Resusci Anne $SkillReporter^{TM}$ (RASR; Laerdal Medical, Stavanger, Norway) and Actar 911 $Squadron^{TM}$ (A911; Vital Signs, New Jersey, USA) held on December 22, 2009. Thirty seven students and two assistants were placed in one laboratory, there were five RASR manikins which provide the LED performance indicator, not the metronome. Forty two students and two assistants were placed in the other laboratory, there were 20 A911 manikins which don't provide any feedback indicator. Chest compression scores and ventilation compression scores obtaining from two groups were analysed statistically by using independent t-test. Results: Chest compression scores, average depth (mm) was 37.5 in RASR and 41.80 A911 (p=.004), too depth (#) was 2.8 in RASR and 19.4 A911 (p=.005), average number per min (#/min) was 64.4 in RASR and 68.2 A911 (p=.038), wrong hand position (#/min) was 10.9 in RASR and 30.8 A911 (p=.040). Four items that showed better scores in group RASR had statistically significant difference. Ventilation compression scores, percent correct (%) was 40.6 in RASR and 20.6 A911 (p<.001), number correct (#) was 4.7 in RASR and 2.1 A911 (p=.002), too fast (#) was 0.9 in RASR and 2.9 A911 (p=.003), average volume (ml) was 536.5 in RASR and 707.1 A911 (p=.011). Also, three items that showed better scores in group RASR had statistically significant difference. Conclusions: Regarding the positive effect of CPR training feedback, comparison between the real-time visual feedback manikin (RASR) and the non-feedback manikin (A911) showed that RASR had better results than A911 in chest compression except average number per min (it means that we need harder chest manikin) and ventilation. Verification of the training effect in the real world such as CPR outcomes is also necessary. A proper application of manikin in training circumstances and research on retention of CPR skills will be needed.

• Journal of the Korean Ceramic Society
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• v.39 no.6
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• pp.523-527
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• 2002

LiMn$_2$O$_4$ compounds were synthesized by calcining a mixture of LiOH and MnO$_2$(CMD) at 47$0^{\circ}C$ for 10 h and then calcining again at $650^{\circ}C$ to 90$0^{\circ}C$ fur 48 h in air with intermediate grinding. All the synthesized samples exhibited XRD patterns for the cubic spinel phase with a space group Fd3m. The lattice parameter increased gradually as the sintering temperature rose. The electrochemical cells were charged and discharged fur 20 cycles at a current density 300$\mu$A/$\textrm{cm}^2$ between 3.5 V and 4.3 V. The voltage vs. discharge capacity curves for all the samples showed two plateaus. The LiMn$_2$O$_4$ sample calcined at 90$0^{\circ}C$ had the largest first discharge capacity. This sample exhibited the best crystallinity, had relatively large lattice parameter and had relatively large particles with rectatively homogeneous size. All the samples showed good cycling performances. Among all the samples, the LiMn$_2$O$_4$ calcined at 85$0^{\circ}C$ had relatively large first discharge capacity and very good cycling performance. The addition of excess LiOH and the mixing in ethanol considered to help the formation of the more LiMn$_2$O$_4$ phase per unit weight sample and the more stable LiMn$_2$O$_4$phase. These led to the larger discharge capacities and the better cycling performances. The cyclic voltammograms fur the second cycle of the LiMn$_2$O$_4$ samples showed the oxidation and reduction peaks around 4.05 V and 4.18 V and around 4.08 V and 3.94 V, respectively. The larger first discharge capacity of the sample calcined at the higher temperature is related to the larger lattice parameter.