• Journal of Environmental Science International
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• v.12 no.12
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• pp.1235-1243
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• 2003

Under controlled conditions in an environmental chamber, 24 experiments were performed to compare the ability of a Variable-Air-Volume/Bypass Filtration System(VAV/BPFS) to remove indoor pollutants and to conserve energy with the ability of conventional Variable Air Volume(VAV) system. The specific conclusions of this paper were; first, the VAV/BPFS was more efficient than the VAV system in removing particulate matter, TVOC, and target VOCs. The total effective removal rate of PM for the VAV/BPFS was two times as high as that of the VAV system. The total effective removal rate of TVOC for the VAV/BPFS was 20 percent higher than that of the VAV system. Also each target VOC concentration was reduced by using the VAV/BPFS. Second, clean air delivery rate was increased by using VAV/BPFS due to additional filtration rate. Otherwise, the VAV/BPFS decreased outdoor supply air rate above 25 percent relative to the rate of VAV system. Third, total energy consumption by the VAV/BPFS was lower than that of the VAV system during the period with indoor thermal load, occupied time. The energy saving of the VAV/BPFS ranged from 11 to 16 percent. The VAV/BPFS improves indoor air quality more efficiently than the VAV system, and it reduced energy consumption. Retrofitting the VAV system with the VAV/BPFS was easy The use of VAV/BPFS is, therefore, recommended far buildings with VAV system as well as for buildings at designing stage.

• Journal of Environmental Science International
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• v.7 no.3
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• pp.327-334
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• 1998

The oil crisis of the 1970s and the rise in oil prices motivated people to implement energy conservation strategies. Buildings were fitted with additional Insulation and reduced ventilation rates. The reduction of mechanical and natural ventilation rate led to Increases In Indoor pollutant concentrations which result- ed In Increased health risks from Indoor exposure to pollutants. The variable-air-volume /bypass fitration system/VAV/BPFS) is a variation of the conventional VAV systems, The VAV/BPFS is an electronically controlled system that provides costegectlve thermal comfort and acceptable indoor air quality Under controlled conditions In a chamber, a series experiments were performed to compare the ability of a VAV/BPFS to remove Indoor aerosol concentration and to reduce energy consumption no that ability of conventional VAV system. Results show that the VAV/BPFS Increases the effective ventilation rate and removes indoor air pollutant, and maintains acceptable indoor air Quality without sacrificing energy consumption.

• Journal of Environmental Health Sciences
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• v.23 no.4
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• pp.57-66
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• 1997

Successful energy conservation and good indcfor air quality (IAQ) are highly dependent on ventilation system. Air filtration is a primary solution of indoor air control strategies in terms of reducing energy consumption and improving ihdoor air quality. A conventional system with bypass filter, as it is called variable-air-volume/bypass filtration system (VAV/BPFS), is a variation of the conventional variable air volume (VAV) systems, which is designed to eliminate indoor air pollutant and to save energy. Bypass filtration system equipped with a high-efficiency particulate filter and carbon absorbent provides additional cleaned air into indoor environments and maintain good IAQ for human health. The objectives of this research were to compare the relative total decay rate of indoor air pollutant concentrations, and to develop a mathematical model simulating the performance of VAV/BPFS. All experiments were performed in chamber under the controlled conditions. The specific conclusions of this research are: 1. The VAV/BPFS system is more efficient than the VAV system in removing indoor air pollutant concentration. The total decay rates of aerosol, and total volatile organic compound (TVOC) for the VAV/BPFS system were higher than those of the conventional VAV system. 2. IAQ model predictions of each pollutant agree closely with the measured values. 3. According to IAQ model evaluation, reduction of outdoor supply air results in decreased dilution removal rate and on increased bypass filtration removal rate with the VAV/BPFS. As a results, we recommends the VAV/BPFS as an alternative to conventional VAV systems.

• BMB Reports
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• v.52 no.11
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• pp.659-664
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• 2019

Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs) obtained from Vav1-deficient ($Vav1^{-/-}$) and wild-type (WT) mice to differentiate into mature OCs upon stimulation with macrophage colony stimulating factor and receptor activator of nuclear kappa B ligand in vitro. Our results suggested that Vav1 deficiency promoted the differentiation of BMMCs into OCs, as indicated by the increased expression of tartrate-resistant acid phosphatase, cathepsin K, and calcitonin receptor. Therefore, Vav1 may play a negative role in OC differentiation. This hypothesis was supported by the observation of more OCs in the femurs of $Vav1^{-/-}$ mice than in WT mice. Furthermore, the bone status of $Vav1^{-/-}$ mice was analyzed in situ and the femurs of $Vav1^{-/-}$ mice appeared abnormal, with poor bone density and fewer number of trabeculae. In addition, Vav1-deficient OCs showed stronger adhesion to vitronectin, an ${\alpha}_v{\beta}_3$ integrin ligand important in bone resorption. Thus, Vav1 may inhibit OC differentiation and protect against bone resorption.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.E
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• pp.45-54
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• 1995

Indoor air quality models are useful to predict indoor air pollutant concentrations as a function of several indoor factors. Indoor air quality model was developed to evaluate the pollutant removal efficiency of variable-air-volume/bypass filtration system (VAV/BPFS) compared with the conventional variable-air-volume (VAV) system. This model provides relative pollutant removal effectiveness of VAV/BPFS by concentration ratio between the conventional VAV system and VAV/BPFS. The predictions agree closely, from 5 to 10 percent, with the measured values for each energy load. As a results, we recommend the VAV/BPFS is a promising alternative to conventional VAV system because it is capable of reducing indoor air pollutant concentration and maintaining good indoor air quality.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.16 no.2
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• pp.184-193
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• 2004

The purpose of this study is to evaluate the performance of various control strategies in commercial buildings which have been operated by the variable air volume (VAV) system. Two buildings in Seoul were chosen for the field study. The one (D building) combined by LonWorks has the constant airflow of supply fan and the proportional control of VAV units (damper type). The other (S building) combined by DDC has the PI control mode of the supply fan and the floating control of VAV units (venturi type). In estimating thermal comfort and energy performance through control modes of PI, PID, and CAV in the supply fan, we could identify several energy efficient operating control strategies for the VAV system.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6417-6421
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• 2015

Viscum album var (VAV) also known as mistletoe, has long been categorized as a traditional herbal medicine in Asia. In addition to its immunomodulating activities, mistletoe has also been used in the treatment of chronic hepatic disorders in China and Korea. There are numerous reports showing that VAV possesses anti-cancer effects, however influence on human hepatocarcinoma has never been elucidated. In the present study, hot water extracts of VAV was evaluated for its potential anti-cancer effect in vitro. SK-Hep1 cells were treated with VAV (50-400ug/ml) for both 24 and 48 hours then cell viability was measured by cell counting kit-8 (CCK-8). Flow cytometry analysis was used to measure the proportion of SK-Hep1 in the different stages of cell cycle. RT-PCR and Western blot analysis were conducted to measure expression of cell cycle arrest related genes and proteins respectively. VAV dose dependently inhibited the proliferation of SK-Hep1 cells without any cytotoxicity with normal Chang liver cell (CCL-13). Flow cytometry analysis showed that VAV extract inhibited the cell cycle of SK-Hep1 cells via G1 phase arrest. RT-PCR and Western blot analysis both revealed that cyclin dependent kinase 2 (Cdk2) and cyclin D1 gene expression were significantly down regulated while p21 was upregulated dose dependently by VAV treatment. Combined down regulation of Cdk2, Cyclin D1 and up regulation of p21 can result in cell death. These results indicate that VAV showed evidence of anti-cancer activity through G1 phase cell cycle arrest in SK-Hep1 cells.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.12 no.7
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• pp.632-641
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• 2000

The present study concerns the simulation of supply-air control in a variable air volume (VAV) system. A stratified lumped thermal model (multi-zone model) is suggested to predict local thermal response of an air-conditioned space. The effects of various thermal parameters such as the cooling system capacity, the thermal mass of air-conditioned space, the time delay of thermal effect, and the building envelope heat transmission are investigated in detail. Further, the influence of control parameters, PI control factor and the sensor location on a VAV system is quantitatively delineated. The results obtained show that the previous homogeneous lumped thermal model (1-zone model) may predict a significantly different thermal response in the air-conditioned space according to the sensor location.

• Journal of the Korean Solar Energy Society
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• v.32 no.4
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• pp.96-102
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• 2012

The minimum airflow of VAV terminal boxes is a key factor for comfort, indoor air quality(IAQ) and energy cost. If the minimum airflow is not reasonable, it would waste energy and make IAQ problems. There are two types of VAV terminal box control logic. One is the single maximum, another is the dual maximum control logic. Dual maximum control logic is more efficiency way to reduce the energy consumption. It has a minimum airflow set point and a heating maximum set point. It allows the minimum airflow set point to be much lower than single maximum control logic. A building simulation was conducted to evaluate the energy consumption and the IAQ according to the control logic of the V AV terminal box. In the simulation, dual maximum control logic can save the energy up to 6.5% compared to the single maximum control logic.

• International Journal of High-Rise Buildings
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• v.8 no.1
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• pp.71-82
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• 2019

The purpose of this study is to evaluate the indoor air quality (IAQ) and energy benefits of a dedicated outdoor air system (DOAS) and compare them with a conventional variable air volume (VAV) system. The DOAS is a decoupled system that supplies only outdoor air, while reducing its consumption using an enthalpy wheel. The VAV system supplies air that is mixed outdoor and transferred indoor. The VAV has the issue of unbalanced ventilation in each room in multiple zones because it supplies mixing air. The DOAS does not have this problem because it supplies only outdoor air. That is, the DOAS is a 100% outdoor air system and the VAV is an air conditioning system. The transient simulations of carbon dioxide concentration and energy consumption were performed using a MATLAB program based on the thermal loads from the model predicted by the TRNSYS 18 program. The results indicated that when the air volume is large, such as in summer, the distribution of air is not appropriate in the VAV system. The DOAS however, supplies the outdoor air stably. Moreover, in terms of annual primary energy consumption, the DOAS consumed approximately 40% less energy than the VAV system.