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Comparison of Dosimetry Protocols in High Energy Electron Beams (고에너지 전자선에 대한 표준측정법간의 비교)

  • 박성용;서태석;김회남;신동오;지영훈;군수일;이길동;추성실;최보영
    • Progress in Medical Physics
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    • v.9 no.4
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    • pp.267-276
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    • 1998
  • Any detector inserted into a phantom should have such a geometry that it caused as small as possible perturbation of the electron fluence. Plane parallel chambers meet this requirement better than other chambers of configurations. IAEA protocol recommends the use of plane parallel chambers for this reason. However, the cylindrical chambers are widely used for convenient. The purpose of this study is to evaluate the absorbed dose due to the differences of four different dosimetry protocols such as IAEA protocol using cylindrical chamber, TG 21 protocol using cylindrical chamber, Markus protocol using plane parallel chamber, and TG 39 report for the calibration of plane parallel chamber in electron beams. Depth-ionization measurements for the electron beams of nominal energy 6, 9, 12, 15, and 18 MeV from Siemens accelerator with a 10$\times$10 cm$^2$ field size were made using a radiation field analyser with 0.125 cc ion chamber. Dosimetric measurements by IAEA and TG 21 protocol were made with a farmer type ionization chamber in solid water for each electron energy, respectively. Dosimetric measurements by Markus protocol were made with a plane parallel ionization chamber in solid water for each electron energy, respectively. The cavity-gas calibration factor for the plane parallel chamber was obtained with the use of 18 MeV electron beam as guided by TG 39 report. Dosimetric measurements by TG 39 were performed with a plane parallel ionization chamber in solid water for each electron energy, respectively. For all the energies and protocols, measurements were made along the central axis of the distance of 100 cm (SSD = 100 cm) with 10$\times$10 cm$^2$ field size at the depth of d$_{max}$ for each electron beam, respectively. In the case of 18 MeV, the discrepancy of 0.9 % between IAEA and TG 21 was found and the two protocols were agreed within 0.7 % for other energies. In the case of 18 MeV and 6 MeV, the discrepancies of $\pm$ 0.8 % between Markus and TG 39 was found, respectively and the two protocols were agreed within 0.5 % for other energies. Since the discrepancy of 1.6 % between cylindrical and plane parallel chamber was found for 18 MeV, it is suggested to get the calibration factor using other method as guided. by TG 39.9.

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765kV 송전선로 건설사업 추진현황

  • 김정호
    • Electric Engineers Magazine
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    • v.189 no.5
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    • pp.65-72
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    • 1998
  • 21세기는 삶의 질 향상과 산업의 선진국형으로의 발전, 그리고 생활형태의 자동화, 정보화 등으로 전력수요가 급격히 증가할 것으로 예상되어 이에 대처하고자 765kV 송전선로 건설을 추진하고 있다. 765kV 송전선로는 345kV 송전선로의 약 5배에 해당하는 전력 수송능력을 가지고 있어 국토가 협소하고 발전단지와 수요지가 멀리 떨어져 있는 우리나라에 적합한 설비라 할 수 있다.

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Size-homogeneous gold nanoparticle decorated on graphene via MeV electron beam irradiation

  • Kim, Yoo-Seok;Song, Woo-Seok;Jeon, Cheol-Ho;Kim, Sung-Hwan;Park, Chong-Yun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.487-487
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    • 2011
  • Recently graphene has emerged as a fascinating 2D system in condensed-matter physics as well as a new material for the development of nanotechnology. The unusual electronic band structure of graphene allows it to exhibit a strong ambipolar electric field effect with high mobility. These properties lead to the possibility of its application in high-performance transparent conducting films (TCFs). Compared to indium tin oxide (ITO) electrodes, which have a typical sheet resistance of ${\sim}60{\Omega}$/sq and ~85 % transmittance in the visible range (400?900 nm), the CVD-grown graphene electrodes have a higher/flatter transmittance in the visible to IR region and are more robust under bending. Nevertheless, the lowest sheet resistance of the currently available CVD graphene electrodes is higher than that of ITO. Here, we report an ingenious strategy, irradiation of MeV electron beam (e-beam) at room temperature under ambient condition, for obtaining size-homogeneous gold nanoparticle decorated on graphene. The nano-particlization promoted by MeV e-beam irradiation was investigated by transmission electron microscopy, electron energy loss spectroscopy elemental mapping, and energy dispersive X-ray spectroscopy. These results clearly revealed that gold nanoparticle with 10 ~ 15 nm in mean size were decorated along the surface of the graphene after 1.5 MeV-e-beam irradiation. A chemical transformation and charge transfer for the metal gold nanoparticle were systematically explored by X-ray photoelectron spectroscopy and Raman spectroscopy. This approach advances the numerous applications of graphene films as transparent conducting electrodes.

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Radiologic Abnormalities in Prolonged SARS-CoV-2 Infection: A Systematic Review

  • Kyongmin Sarah Beck;Jeong-Hwa Yoon;Soon Ho Yoon
    • Korean Journal of Radiology
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    • v.25 no.5
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    • pp.473-480
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    • 2024
  • We systematically reviewed radiological abnormalities in patients with prolonged SARS-CoV-2 infection, defined as persistently positive polymerase chain reaction (PCR) results for SARS-CoV-2 for > 21 days, with either persistent or relapsed symptoms. We extracted data from 24 patients (median age, 54.5 [interquartile range, 44-64 years]) reported in the literature and analyzed their representative CT images based on the timing of the CT scan relative to the initial PCR positivity. Our analysis focused on the patterns and distribution of CT findings, severity scores of lung involvement on a scale of 0-4, and the presence of migration. All patients were immunocompromised, including 62.5% (15/24) with underlying lymphoma and 83.3% (20/24) who had received anti-CD20 therapy within one year. Median duration of infection was 90 days. Most patients exhibited typical CT appearance of coronavirus disease 19 (COVID-19), including ground-glass opacities with or without consolidation, throughout the follow-up period. Notably, CT severity scores were significantly lower during ≤ 21 days than during > 21 days (P < 0.001). Migration was observed on CT in 22.7% (5/22) of patients at ≤ 21 days and in 68.2% (15/22) to 87.5% (14/16) of patients at > 21 days, with rare instances of parenchymal bands in previously affected areas. Prolonged SARS-CoV-2 infection usually presents as migrating typical COVID-19 pneumonia in immunocompromised patients, especially those with impaired B-cell immunity.

High-Level Expression of T4 Endonuclease V in Insect Cells as Biologically Active Form

  • Kang, Chang-Soo;Son, Seung-Yeol;Bang, In-Seok
    • Journal of Microbiology and Biotechnology
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    • v.16 no.10
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    • pp.1583-1590
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    • 2006
  • T4 endonuclease V (T4 endo V) [EC 3. 1. 25. 1], found in bacteriophage T4, is responsible for excision repair of damaged DNA. The enzyme possesses two activities: a cyclobutane pyrimidine dimer DNA glycosylase (CPD glycosylase) and an apyrimidic/apurinic endonuclease (AP lyase). T4 denV (414 bp cDNA) encoding T4 en do V (138 amino acid) was synthesized and expressed using either an expression vector, pTriEx-4, in E. coli or a baculovirus AcNPV vector, pBacPAK8, in insect cells. The recombinant His-Tag/T4 endo V (rHis-Tag/T4 endo V) protein expressed from bacteria was purified using one-step affinity chromatography with a HiTrap Chelating HP column and used to make rabbit anti-His-Tag/T4 endo V polyclonal antibody for detection of recombinant T4 endo V (rT4 endo V) expressed in insect cells. In the meantime, the recombinant baculovirus was obtained by cotransfection of BacPAK6 viral DNA and pBP/T4 endo V in Spodoptera frugiperda (Sf21) insect cells, and used to infect Sf21 cells to overexpress T4 endo V protein. The level of rT4 endo V protein expressed in Sf21 cells was optimized by varying the virus titers and time course of infection. The optimal expression condition was set as follows; infection of the cells at a MOI of 10 and harvest at 96 h post-infection. Under these conditions, we estimated the amount of rT4 endo V produced in the baculovirus expression vector system to be 125 mg/l. The rT4 endo V was purified to homogeneity by a rapid procedure, consisting of ion-exchange, affinity, and reversed phase chromatographies, based on FPLC. The rT4 endo V positively reacted to an antiserum made against rHis-Tag/T4 endo V and showed a residual nicking activity against CPD-containing DNA caused by UV. This is the first report to have T4 endo V expressed in an insect system to exclude the toxic effect of a bacterial expression system, retaining enzymatic activity.

A Study on the Driving Characteristics of Microbial Fuel Cell Using Mixed Strains in Domestic Wastewater (생활폐수 내 혼합균주를 이용한 미생물 연료전지의 구동 특성에 관한 연구)

  • KIM, SANG KYU;YOO, DONG JIN
    • Transactions of the Korean hydrogen and new energy society
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    • v.32 no.6
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    • pp.506-513
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    • 2021
  • The use of fossil fuels is a major contributor to the increase atmospheric greenhouse gas emissions. As such problems arise, interest in new and renewable energy devices, particularly fuel cells, is greatly increasing. In this study, various characteristics of mixed strains were observed in wastewater collected by the Jeonju Environment Office to investigate the effects of microorganisms on voltage generation and voltage generation of substrates, electrode materials, electrons, electron transport media, and ash microbial fuel cells. As a result of separately measuring the voltage generated during inoculation, the inoculation voltage of Escherichia coli K12 (E. coli K12) was 0.45 V, and the maximum inoculation voltage of the mixed strain was 1.2 V. Thereafter, voltage values were collected using a digital multimeter and the amount of voltage generated over time was measured. In the case of E. coli K12, the maximum voltage reached 0.45 V, and the cell voltage was maintained above 0.23 V for 140 hours. In contrast, for the mixed strain, the maximum voltage reached 1.2 V and the voltage was slowly decreased to 0.97 V. In addition, the degree of microbial adsorption to the electrod surface after the inoculation test was confirmed using a scanning electron microscope. Therefore, these results showed the possibility of purifying pollutants at the same time as power generation through the production of hydrogen ions using microorganisms and wastewater.

The Temperature Dependent C-H/V Constitutive Modeling for Magnesium Alloy Sheet (마그네슘 판재를 위한 온도 의존형 C-H/V 구성 모델에 관한 연구)

  • Park, J.H.;Lee, J.K.;Kim, H.Y.
    • Transactions of Materials Processing
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    • v.21 no.4
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    • pp.221-227
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    • 2012
  • The automotive and electronic industries have seriously considered the use of magnesium alloys because of their excellent properties such as strength to weight ratio, EMI shielding capability, etc. However, it is difficult to form magnesium alloys at room temperature because of the mechanical deformation related to twinning. Hence, magnesium alloys are normally formed at elevated temperatures. In this study, a temperature dependent constitutive model, the C-H/V model, for the magnesium alloy AZ31B sheet is proposed. A hardening law based on nonlinear kinematic and H/V(Hollomon/Voce) hardening model is used to properly characterize the Bauschinger effect and the stabilization of the flow stress. Material parameters were determined from a series of uni-axial cyclic experiments(C-T-C) with the temperature ranging between 150 and $250^{\circ}C$. The developed models are fit to experimental data and a comparison is made.

Simultaneous Observations of SiO and $H_2O$ Masers toward Symbiotic Stars

  • Cho, Se-Hyung;Kim, Jae-Heon
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.79.2-79.2
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    • 2010
  • We present the results of simultaneous observations of SiO v=1, 2, J=1-0, $^{29}SiO$ v=0, J=1-0, and $H_2O$ $6_{16}-5_{23}$ maser lines performed with the KVN Yonsei 21 m radio telescope from 2009 Nov. to 2010 Jan (ApJ, 719, 126, 2010). We searched for these masers in 47 symbiotic stars and detected maser emission from 21 stars, giving the first time detection from 19 stars. Both SiO and $H_2O$ masers were detected from seven stars of which six stars are D-type symbiotic and one is an S-type star, WRAY 15-1470. In the SiO maser emission, the $^{28}SiO$ v=1 maser was detected from 10 stars, while the v=2 maser detected from 15 stars. In particular, the $^{28}SiO$ v=2 maser emission without the v=1 maser detection was detected from nine stars with its detection rate of 60 %, which is much higher than that of isolated Miras/red giants. The $^{29}SiO$ v=0 maser emission was also detected from two stars, H 2-38 and BF Cyg, together with the $^{28}SiO$ v=2 maser. We conclude that these different observational results between isolated Miras/red giants and symbiotic stars may be related with the presence of hot companions in a symbiotic binary system.

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Experimental Animal Models of Coronavirus Infections: Strengths and Limitations

  • Mark Anthony B. Casel;Rare G. Rollon;Young Ki Choi
    • IMMUNE NETWORK
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    • v.21 no.2
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    • pp.12.1-12.17
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    • 2021
  • Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the emergence of SARS-CoV-2 in the human population in late 2019, it has spread on an unprecedented scale worldwide leading to the first coronavirus pandemic. SARS-CoV-2 infection results in a wide range of clinical manifestations from asymptomatic to fatal cases. Although intensive research has been undertaken to increase understanding of the complex biology of SARS-CoV-2 infection, the detailed mechanisms underpinning the severe pathogenesis and interactions between the virus and the host immune response are not well understood. Thus, the development of appropriate animal models that recapitulate human clinical manifestations and immune responses against SARS-CoV-2 is crucial. Although many animal models are currently available for the study of SARS-CoV-2 infection, each has distinct advantages and disadvantages, and some models show variable results between and within species. Thus, we aim to discuss the different animal models, including mice, hamsters, ferrets, and non-human primates, employed for SARS-CoV-2 infection studies and outline their individual strengths and limitations for use in studies aimed at increasing understanding of coronavirus pathogenesis. Moreover, a significant advantage of these animal models is that they can be tailored, providing unique options specific to the scientific goals of each researcher.

A Study on the Detection of Solar Power Plant for High-Resolution Aerial Imagery Using YOLO v2 (YOLO v2를 이용한 고해상도 항공영상에서의 태양광발전소 탐지 방법 연구)

  • Kim, Hayoung;Na, Ra;Joo, Donghyuk;Choi, Gyuhoon;Oh, Yun-Gyeong
    • Journal of Korean Society of Rural Planning
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    • v.28 no.2
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    • pp.87-96
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    • 2022
  • As part of strengthening energy security and responding to climate change, the government has promoted various renewable energy measures to increase the development of renewable energy facilities. As a result, small-scale solar installations in rural areas have increased rapidly. The number of complaints from local residents is increasing. Therefore, in this study, deep learning technology is applied to high-resolution aerial images on the internet to detect solar power plants installed in rural areas to determine whether or not solar power plants are installed. Specifically, I examined the solar facility detector generated by training the YOLO(You Only Look Once) v2 object detector and looked at its usability. As a result, about 800 pieces of training data showed a high object detection rate of 93%. By constructing such an object detection model, it is expected that it can be utilized for land use monitoring in rural areas, and it can be utilized as a spatial data construction plan for rural areas using technology for detecting small-scale agricultural facilities.