• Title/Summary/Keyword: V(IV)

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Antioxidant and Antiallergic Activity of Compounds from the Aerial Parts of Scutellaria baicalensis Georgi (황금 지상부의 항산화 및 항 알러지 활성 성분)

  • Cha Ja-Hyun;Kim Hyun-Wok;Kim Sun-Gun;Jung Sung-Hee;Whang Wan-Kyunn
    • YAKHAK HOEJI
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    • v.50 no.2
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    • pp.136-143
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    • 2006
  • Roots of Scutellaria baicalensis have been used for fever remedy; diuresis, antiphlogistic. For the investigation of the active component from aerial parts of Scutellaria baicalensis, MeOH extracts from aerial parts of Scutellaria baicalensis were suspended with $H_2O$, and partitioned by $CHCl_3$. In order to investigate the efficacy of antioxidative activity the activity guided fraction and isolation of physiologically active substance were peformed. Its $H_2O,\;30\%,\;60\%$ MeOH and MeOH fractions were examined on antioxidative activity using DPPH method and TBARS assay; It was revealed that $30\%\;and\;60\%$ MeOH fractions have significant anti-oxidative activity. its fractions testing type I allergy, compound 48/80 induced systemic anaphylaxis was applied. As a result, compared with reference (cromolygate), these fraction significantly inhibited systemic anaphylaxis by $71\%\;and\;57\%$, respectively. From $30\%,\;60\%$ MeOH fraction, five compounds were isolated and elucidated apigenin 6-C-${\alpha}$-L-arabinopyranosyl-8-C-${\beta}$-D-glucopyranoside (isoschaftside, I), scutellarein 7-O-${\beta}$-D-glucuronopyranoside (scutellarin, II), apigenin 7-O- ${\beta}$-D-glucuronopyranoside (III), isoscutellarein 8-O-${\beta}$-D-glucuronopyranoside (IV), kaempferol 3-O-${\beta}$-D-glucopyranoside (V) through their physicochemical data and spectroscopic methods. We measured radical scavenging activity with DPPH method and anti-lipid peroxidative efficacy on human LDL with TBARS assay. [$I] showed antioxidant activities in order. Type I allergy compound 48/80 induced systemic anaphylaxis was applied. $[V inhibited systemic anaphylaxis in order.

Efficiency of Embolization for Kidney Injury (신손상 환자에서 혈관 색전술의 효용성)

  • Kwon, Young-Kee;Chang, Hyuk-Soo;Kim, Byung-Hoon;Park, Choal-Hee;Kim, Chun-Il
    • Journal of Trauma and Injury
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    • v.23 no.1
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    • pp.16-20
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    • 2010
  • Purpose: High-grade (III, IV, V) renal injury may need interventional management. We investigated whether the selective embolization of the renal artery is effective for the treatment of major renal injury in comparison with emergency renal exploration. Methods: We retrospectively reviewed the medical and radiologic records of patients who underwent surgery or embolization for renal injury (Grade III, IV, V) between January 1990 and December 2007. We analyzed the change in treatment method before and after 2000, the blood pressure, the hemoglobin at the time of visit, the hospital days and the complications in patients who received surgery or embolization. Preserved renal functions of the embolized kidneys were identified by using enhanced CT. Results: Cases of surgery and embolization were 37 and 13, respectively: 5 and 4 in renal injury grade III, 17 and 6 in grade IV and 13 and 3 in grade V. Cases of surgery and embolization were 33 and 1 before 2000 and 2 and 12 after 2000, repectively: embolizations increased after 2000. No significant differences in mean diastolic pressure, hemoglobin, hospital days and complications existed between the surgery and the embolization groups (p>0.05). However, the transfusion volume was significantly smaller in the embolization group (p<0.05). One postoperative complication occurred in the surgery group. We identified the preserved renal functions of the embolized kidney by using enhanced CT. Conclusion: Embolization could be one treatment method for high-grade renal injury. Thus, we might suggest selective embolization a useful method for preserving the renal function in cases of high-grade renal injury.

Sex Differences in Cerebellar Structure of Healthy Adults (정상 성인에서 남녀의 소뇌 구조 차이)

  • Kim, Ji-Hyun H.;Bae, Su-Jin;Ryu, Keun-Taik;Kang, Min-Seong;Lim, Soo-Mee;Lee, Sun-Ho;Lee, So-Jin;Ko, Eun;Jeong, Do-Un
    • Korean Journal of Biological Psychiatry
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    • v.19 no.2
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    • pp.77-83
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    • 2012
  • Objectives : Although there have been studies that examine sex differences of the brain structures using magnetic resonance imaging, studies that specifically investigate cerebellar structural differences between men and women are scarce. The purpose of current study was to examine sex differences in structures of the cerebellum using cerebellar template and cerebellum analysis methods. Methods : Sixteen men and twenty women were included in the study. A MATLAB based program (MathWorks, Natick, MA, USA), Statistical Parametric Mapping 5 (SPM5) using the spatially unbiased infra-tentorial atlas template (SUIT) as the cerebellum template, was used to analyze the brain imaging data. Results : There was no significant difference in age between men (mean age=28.1) and women (mean age=27.2). Men showed higher gray matter density than women in two left cerebellar areas including the clusters in the lobules IV and V (a cluster located across the lobules IV and V), and the lobule VIIIb (lobules IV and V, t=4.75, p<0.001 ; lobule VIIIb, t=3.08, p=0.004). Conclusions : The current study found differences in cerebellar gray matter density between men and women. The current study holds its significance for applying the template specifically developed for the analysis of cerebellum.

Blood Flow Changes by Anastomotic Method in Fontan Operation (폰탄 수술에서 문합방법에 따른 혈류 변화)

  • Kim, S.H.;Park, Y.H.;Cho, B.K.;Kim, J.H.;Hong, Y.S.;Kim, Y.H.;Kim, S.S.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.203-206
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    • 1996
  • To understand the local fluid dynamics for different desists of Fontan operation, five models were made out of Pyrex glass to facilitate in-vitro study. Model I, II and III have same position of the center of the anastomosis of the IVC( inferior vena cava) with that of the SVC(superior vena cava), but Model IV and V have 10 mm offset between them. Also the anastomotic junction angles are different(Model I and $IV:90^{\circ}$, Model II and $V:70^{\circ}$, Model $III:45^{\circ}$). These models were then connected to a flow loop for flow visualization study. In Model I any dominant vortex was not seen in the central region of the juntion, but a large unstable vortex was created in the Model II and III. In Model IV and V a significant stagnation region was created in the middle of the offset region. It also showed that the flow direction from the IVC and SVC to the LPA(left pulmonary artery) and RPA(right pulmonary artery) highly depends on the offset of the junction rather than the anastomotic junction angle.

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Studies on the Protein of Korean Soybeans Part 2; Paper Electrophoresis of the Proteins of Korean Soybeans (한국산(韓國産) 대두(大豆)의 단백질(蛋白質)에 관(關)한 연구(硏究) (제2보(第2報)); 여지전기영동법(濾紙電氣泳動法)에 의(依)한 대두단백질(大豆蛋白質)의 분석(分析))

  • Byun, S.M.;Kim, Z.U.;Lee, C.Y.
    • Applied Biological Chemistry
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    • v.7
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    • pp.85-91
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    • 1966
  • Paper electrophoretic separation of soybean protein using phosphate buffer(pH. 7.6, I. 0.18) was carried out and revealed five components. The ratio of each component extracted with the phosphate buffer was estimated as follows. Component %(aver.) Component I 14.47 Component II 7.22 Component III 4.43 Component IV 71.7 Component V 2.18 Also, each component of phosphate buffer extract was identified as: Component identified Component I identified phaseolin Component II identified glutelin Component III identified $albumin\;{\alpha}$ Component IV identified glycinin Component V identified $albumin\;{\alpha}$ The quantitative determination of the components was performed with twenty five varieties of Korean soybean and turned out to indicate marked difference between the varities in the ratio of the components.

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Analysis on the Marketing Efficieny of Paprika (착색단고추의 유통효율성 분석)

  • Sim, Jong-Sub;Kim, Jin-Suk
    • Journal of agriculture & life science
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    • v.44 no.1
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    • pp.69-80
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    • 2010
  • The purpose of this study is to analyse current marketing practices and marketing efficiency using operational efficiency. Through field survey on marketing situations and channels, we found that major marketing channels of paprika were classified into six types : channels in exporting market included (1) producer's organization leading channel (type I), (2) regional cooperative leading channel (type II), (3) individual producer leading channel (type III), and channels in domestic market included (4) wholesale markets targeting channel (type IV), (5) distribution agents targeting channel (type V), (6) cooperative system selling channel (type VI). According to the estimated result of operational efficiency of marketing channels, marketing efficiency of type III and IV was relatively higher than type I,II and type V, VI respectively.

The Mechanism Study of Cheonghunhwadam-tang Gamypang on the Regional Cerebral Blood Flow and Mean Arterial Blood Pressure in Rats(IV) (청훈화담탕가미방이 국소뇌혈유량 및 평균혈압에 미치는 작용기전 연구(IV))

  • Jeong Hyun Woo;Kim Cheon Joong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.1013-1018
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    • 2003
  • Cheonghunhwadam-tang(CHT) have been used in oriental medicine for many centuries as a therapeutic agent of vertigo by wind, fire and phlegm. CTG was CHT adding Aurantii FructusㆍGastrodae Rhizoma. CTG was significantly increased regional cerebral blood f1ow(rCBF) in a dose-dependent, and CTG was decreased mean arterial blood pressure(MABP) compared with normal MABP(100%) in a low dosage, but was increased MABP in a dose-dependent, was aliked with normal MABP in a high-dosage. Therefore, purpose of this Study was to investigate experimental mechanism of CHTAG on the cerebral hemodynamics(rCBF, MABP) in rats. The changes of rCBF and MABP were determinated by Laser-Doppler Flowmetry(LDF). The results were as follows ; Pretreatment with indomethacin(3㎎/㎏, i.v.) was significantly inhibited CTG induced increase of rCBF and pretreated with propranolol(3㎎/㎏, i.v.) was inhibited CTG induced increase of rCBF, but pretreatment with methylene blue(10㎍/㎏, i.v) was increased CTG induced increase of rCBF. Pretreatment with indomethacin was decreased CTG induced increase of MABP, but pretreatment with propranolol and methylene blue were increased CTG induced increase of MABP. This results suggest that the mechanism of CTG is mediated by cyclooxygenase.

Synthesis of Damascones and Related Flavoring Compound : ${\bdta}$-Damascone (다마스콘 및 관련 향료물질의 합성 : 베타다마스콘)

  • Lee Woo Young;Jung Mee Park;Ki Hong Nam;Se Young Jang;Oee Sook Park
    • Journal of the Korean Chemical Society
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    • v.30 no.5
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    • pp.483-487
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    • 1986
  • The synthesis of $\beta-damascone$ (I), an odoriferous natural product, was investigated from 2,2,6-trimethylcyclohexanone (II); (II) was ethynylated by the action of monoacetylide anion prepared from acetylene and sec-butyllithium at -78${\circ}C$, to give an ethynylcarbinol(III), which was isomerized to an acetylcyclohexene(IV) by refluxing in aqueous oxalic or formic acid. (IV) was treated with sec-butyllithium, the enolate was reacted with freshly dried acetaldehyde, and the resultant $\beta-hydroxyketone$ (V) was dehydrated by TsOH to ${\beta}$-damascone, trans-2,6,6-trimethyl-1-crotonyl-1-cyclohexene(I).

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A Study on the Trace Analysis of Germanium in Inorganic Matrices by Differential Pulse Polarography (Differential Pulse Polarography에 의한 무기물 시료 중 Germanium의 미량 분석에 관한 연구)

  • Shin, Ho-Sang;Oh, Yun-Suk;Shin, Hak-Soo
    • Analytical Science and Technology
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    • v.9 no.3
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    • pp.253-261
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    • 1996
  • Analytical method for the determination of trace germanium in inorganic matrices by differential pulse polarography(DPP) was studied. The reduction peak of germanium(IV) in perchloric acid solution containing 1, 2, 3-trihydroxy benzene appeared at -0.45V(vs. Ag/AgCl) and the peak current for germanium complex varied linearly with concentration variation. Factors affecting sensitivity and precision for germanium quantification were studied and detection limit under the investigated parameters was 1ng/ml. Inorganic samples were decomposed by fusion with potassium pyrosulfate. Serious interferences of Se(IV), Pb(II), As(III) for the determination of germanium were discussed. Interferences of these elements could be avoided by extraction of germanium from decomposed matrices by $CCl_4$ in 10M HCl solution. The germanium contents of inorganic samples(Pb bf. dust, Cu bf. dust, gneiss, Cu anode slime) were determined by the above method.

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The Development and It′s Characteristics of New Film Dosimetry Algorithm for Personal Dosimetry (개인피폭 선량 측정을 위한 필름 배지 선량계의 새로운 알고리즘 개발 및 특성)

  • 이병용;장혜숙;봉정균;권수일
    • Progress in Medical Physics
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    • v.6 no.2
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    • pp.35-40
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    • 1995
  • Purpose: We have developed new film dosimetry algorithm for personal dosimetry and examined its characteristics. Materials and methods: Agfagaevart personal monitoring 2/10 films are used. Films which are in the film badges filtered with Cu 0.3mm, plastic 1.5mm, Aluminum 0.6mm and tin 0.8mm, were exposed by standard dosimetry laboratory. Irradiated energy categories are ANSI N13.1l Category III, and IV. Manual type film precessor and X-rite film densitometor was used. Filtered densities to energy relations and does to transformed densities relations can be obtained ofter transformation of H&D curves to linear shape by polynomal fitting. Reults : Personal dose be determined within 25% error for category m and 15% for category IV. And we are able to evaluate the exposed energy. Conclusion : New algorithm developed in this study is good for personal dosimetry within 30% error range for catergory III and IV. It is expectd to be complete personal dosimetry algorithm with further study for categrory, I, Dand II V.

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