• Title/Summary/Keyword: Uterine adenosarcoma

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MR Imaging Findings of Tamoxifen-associated Uterine Adenosarcoma: Report of Two Cases

  • Choi, Soo Yeon;Sung, Deuk Jae;Han, Na Yeon;Park, Beom Jin;Kim, Min Ju;Sim, Ki Choon;Cho, Sung Bum
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.1
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    • pp.56-61
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    • 2015
  • Adenosarcoma of the uterus is a rare biphasic tumor containing benign glandular epithelial and malignant mesenchymal components. The tumor has been reported to be associated with antiestrogen therapy, particularly tamoxifen, but there have been a few case reports with MRI. We present two cases of MRI findings of uterine adenosarcoma after antiestrogen therapy, tamoxifen and toremifene in breast cancer patients. The tumor presents as a large polypoid mass occupying the endometrial cavity, and may protrude into the vagina. On MRI, the tumor typically shows solid components with scattered small cysts and heterogeneous enhancement. These findings are not significantly different from conventional adenosarcoma.

Current Status of Magnetic Resonance Imaging in Patients with Malignant Uterine Neoplasms: A Review

  • Yu-Ting Huang;Yen-Ling Huang;Koon-Kwan Ng;Gigin Lin
    • Korean Journal of Radiology
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    • v.20 no.1
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    • pp.18-33
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    • 2019
  • In this study, we summarize the clinical role of magnetic resonance imaging (MRI) in the diagnosis of patients with malignant uterine neoplasms, including leiomyosarcoma, endometrial stromal sarcoma, adenosarcoma, uterine carcinosarcoma, and endometrial cancer, with emphasis on the challenges and disadvantages. MRI plays an essential role in patients with uterine malignancy, for the purpose of tumor detection, primary staging, and treatment planning. MRI has advanced in scope beyond the visualization of the many aspects of anatomical structures, including diffusion-weighted imaging, dynamic contrast enhancement-MRI, and magnetic resonance spectroscopy. Emerging technologies coupled with the use of artificial intelligence in MRI are expected to lead to progressive improvement in case management of malignant uterine neoplasms.