• Title/Summary/Keyword: Uterine Cervical Cancer

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Diagnosis of Recurrent Uterine Cervical Cancer: Computed Tomography versus Positron Emission Tomography

  • Dong Hee Park;Kie Hwan Kim;Sang Yoon Park;Byung Hee Lee;Chang Woon Choi;Soo Yil Chin
    • Korean Journal of Radiology
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    • v.1 no.1
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    • pp.51-55
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    • 2000
  • Objective: To determine the accuracy of CT and positron emission tomography (PET) in the diagnosis of recurrent uterine cervical cancer. Materials and Methods: Imaging findings of CT and PET in 36 patients (mean age, 53 years) in whom recurrent uterine cervical cancer was suspected were analyzed retrospectively. Between October 1997 and May 1998, they had undergone surgery and/or radiation therapy. Tumor recurrence was confirmed by pathologic examination or follow-up studies. Results: In detecting recurrent uterine cervical cancer, the sensitivity, specificity, and accuracy of CT were 77.8%, 83.3%, and 80.5%, respectively, while for PET, the corresponding figures were 100%, 94.4%, and 97.2%. The Chi-square test revealed no significant difference in specificity (p = .2888), but significant differences in sensitivity (p = .0339) and accuracy (p = .0244). Conclusion: PET proved to be a reliable screening method for detecting recurrent uterine cervical cancer, but to determine the anatomical localization of recurrent tumors, and thus decide an adequate treatment plan, CT was eventually needed.

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A Case of Recurred Uterine Cervical Cancer Presented as Only Huge Mediastinal Mass (국소병변없이 거대한 종격동 종괴로만 재발된 자궁경부암 1예)

  • Lee, Jun Seok;Gong, Soo Jung;Joo, Jong Eun;Lee, Jung Ae;Kim, Jeong Seon;Ahn, Young Soo
    • Tuberculosis and Respiratory Diseases
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    • v.60 no.6
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    • pp.684-689
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    • 2006
  • Uterine cervical cancer is the $5^{th}$ most common malignancy in Korean women. With the development of new diagnostic and therapeutic modalities, earlier stage cancers are being diagnosed with longer survival rates being anticipated. Accordingly, recurrent cancers are being encountered more often in clinical practice. Most recurrent uterine cervical cancer patients, have intra-pelvic lesions and adjacent lymph node involvement, while a distant metastasis alone is extremely rare. A mediastinal recurrence of uterine cervical cancer is not common with most manifesting as small lymph node enlargements. We report a case of a 46-year-old woman with recurrent uterine cervical cancer presenting only as a huge mediastinal mass without a local recurrence.

Psychometric Evaluation of Uterine Cervical Cancer Screening Embarrassment Questionnaire among Korean Women: Complementary Use of Rasch Model

  • Cho, Eun-Jung;Chung, Bok-Yae;Lee, Kwan;Consedine, Nathan S.;Lee, Won-Kee
    • Women's Health Nursing
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    • v.17 no.5
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    • pp.463-473
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    • 2011
  • Purpose: Cervical cancer can be prevented by regular cervical screening. Embarrassment has been reported as one important barrier to cervical screening uptake. The absence of appropriate instrumentation, however, has limited our understanding of the links between embarrassment and health care outcomes. The purpose of this study was to evaluate psychometric attributes of the uterine cervical cancer screening embarrassment questionnaire. Methods: A convenience sample for field study was recruited from four gynecological clinics in Gyeongju, Korea. Within a cross-sectional descriptive design, 339 women who had cervical screening completed self-administered measures of embarrassment including a visual analogue, general medical embarrassment, dispositional embarrassment, and Pap smear related negative emotion. Results: Rasch analysis of items demonstrated the evidence of one-dimensional construct and good 7-point rating scales functioning. Factor analysis revealed that uterine cervical cancer screening embarrassment was comprised of two domains-bodily manifestations and perceiving an undesirable social face. Construct validity was demonstrated by a high subscale-to-subscale correlation. Convergent and discriminant validity was evidenced by significant correlations with a 100 mm VAS scale, general medical embarrassment, and Pap smear related negative emotion. Known-group validity was established by comparing women with high versus low trait embarrassment. Both two sub-scales and overall scale demonstrated good internal reliability. Conclusion: The Uterine uterine cervical cancer screening questionnaire is a reliable and valid instrument suited to assessing the manifestations of embarrassment during screening. The use of instrument can be extended to understand the client's embarrassment undergoing health examinations which require the exposure of their private parts.

Nucleus Recognition of Uterine Cervical Pap-Smears using FCM Clustering Algorithm

  • Kim, Kwang-Baek
    • Journal of information and communication convergence engineering
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    • v.6 no.1
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    • pp.94-99
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    • 2008
  • Segmentation for the region of nucleus in the image of uterine cervical cytodiagnosis is known as the most difficult and important part in the automatic cervical cancer recognition system. In this paper, the region of nucleus is extracted from an image of uterine cervical cytodiagnosis using the HSI model. The characteristics of the nucleus are extracted from the analysis of morphemetric features, densitometric features, colormetric features, and textural features based on the detected region of nucleus area. The classification criterion of a nucleus is defined according to the standard categories of the Bethesda system. The fuzzy C-means clustering algorithm is employed to the extracted nucleus and the results show that the proposed method is efficient in nucleus recognition and uterine cervical Pap-Smears extraction.

Uterine Cervical Cancer: Emphasis on Revised FIGO Staging 2018 and MRI (자궁경부암: 개정된 2018 FIGO 병기와 자기공명영상을 중심으로)

  • Weon Jang;Ji Soo Song
    • Journal of the Korean Society of Radiology
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    • v.82 no.5
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    • pp.1083-1102
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    • 2021
  • Uterine cervical cancer is a common gynecological cancer prevalent in Korea. Early detection, precise diagnosis, and appropriate treatment can affect its prognosis. Imaging approaches play an important role in staging, treatment planning, and follow-up. MRI specifically provides the advantage of assessing tumor size and disease severity with high soft tissue contrast. The revised version of the International Federation of Gynecology and Obstetrics (FIGO) staging system has been introduced in 2018, which incorporates subdivided primary tumor size and lymph node metastasis. In this review, the staging of uterine cervical cancer based on previous studies, the recently revised FIGO staging, and various post-treatment images are primarily described using MRI.

Effects of the Self-efficacy Promoting Program for Prevention of Uterine Cervical Cancer on Self-efficacy and Performance of Preventive Health Behaviors in Nurses (자궁경부암 예방을 위한 자기효능증진 프로그램이 간호사의 자기효능감과 예방행위 수행에 미치는 영향)

  • Tae, Young sook
    • Korean Journal of Adult Nursing
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    • v.18 no.1
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    • pp.22-30
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    • 2006
  • Purpose: This study was conducted to identify the effects of the self efficacy promoting program on self efficacy and performance of preventive health behavior of uterine cervical cancer for community nurses. Method: A one group quasi-experimental research with pre and post test design was used. The subjects of the study were consisted of twenty two community nurses in a city in Korea. The whole program was carried out from July to September, 2003. The effect of the program was analyzed at the first week, the fifth week, and the ninth week since the experiment input began. Data were analyzed with repeated ANOVA to determine the effects of program. Results: 1) After the self efficacy promoting program, self efficacy scores were significantly increased compared to those before the program(F=12.029. p=0.005). 2) After the self efficacy promoting program, preventive health behavior scores were significantly increased than those before the program(F=10.431. p=0.006). Conclusions: This 9-week program showed much affirmative effect on the prevention of uterine cervical cancer for community nurses. Thus this program can be recommended to the management of the prevention and early detection of uterine cancer.

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Unusual Peritoneal Metastasis of Late Recurrent Uterine Cervical Cancer: A Case Report and Literature Review (후기 재발성 자궁 경부암의 비전형적인 복막 전이: 증례 보고 및 문헌 고찰)

  • Sangmin Park;Hee Jin Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.4
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    • pp.904-909
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    • 2022
  • Uterine cervical cancer is one of the most common malignancies of the female genital tract. Most recurrent cases of uterine cervical cancer are diagnosed within two years after primary treatment, and late recurrence after a disease-free interval of more than five years is rare. In addition, peritoneal metastases usually present as multifocal discrete nodules in the peritoneal cavity with nodular or diffuse peritoneal thickening. Herein, we report an extremely rare case of late recurrent cervical cancer peritoneal metastasis with an unusual manifestation of a large, solitary necrotic mass in the right subphrenic space on contrast-enhanced CT.

Clinical and histopathologic analysis of gynecological cancer: a single institute experience over 7 years

  • Lee, Soo-Young;Kim, Eunbyeol;Kim, Hyo-Shin;Koo, Yu-Jin;Lee, Dae-Hyung
    • Journal of Yeungnam Medical Science
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    • v.37 no.3
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    • pp.179-185
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    • 2020
  • Background: Approximately 100,000 women are diagnosed with cancer each year in Korea. According to a survey by the Korean central cancer registry in 2016, uterine cervical cancer, uterine corpus cancer, and ovarian cancer were the 5th, 7th, and 8th most prevalent cancers respectively among Korean women. The present study aims to review the clinico-pathologic characteristics of patients who were treated for major gynecological malignancies at Yeungnam University Medical Center. Methods: Patients with invasive gynecological cancers from January 2012 to February 2019 were retrospectively identified. We analyzed the clinical features, demographic profiles, pathologic data, treatment modality used, adjuvant treatment used, complications, recurrence, and survival outcomes. Results: A total of 287 patients (cervical cancer 115; corporal cancer 86; and ovarian, tubal, or primary peritoneal cancer 90) were included. Most cervical (82.7%) and corporal cancers (89.5%) were diagnosed in the early stages (stage I or II), while more than half (58.9%) the cases of ovarian, tubal or peritoneal cancers were diagnosed in the advanced stages (stage III or IV). Surgical complications were observed in 12.2% of cervical cancers, 16.3% of uterine corpus cancers, and 11.1% of ovarian, tubal, and peritoneal cancers, respectively. The 5-year overall survival rate was 94.1%, 91.0%, and 77.1% for cervical, corporal, and ovarian, tubal, or peritoneal cancers, respectively. Conclusion: Surgical treatment was satisfactory in terms of the incidence of complications, and survival outcomes were generally good. Clinicians should be aware of the clinical and histopathological characteristics of patients with gynecological cancers to be able to provide optimal strategies and counseling.

High Dose Rate Cobalt-60 After Loading Intracavitary Therapy of the Uterine Cervical Carcinoma in Srinagarind Hospital, Analysis of Residual Disease

  • Pesee, Montien;Krusun, Srichai;Padoongcharoen, Prawat
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4835-4837
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    • 2012
  • Objectives: To evaluate residual disease in uterine cervical cancer patients treated with teletherapy using combined high dose rate Cobalt-60 brachytherapy. Materials and Methods: A retrospective study of uterine cervical cancer patients, FIGO stages IB-IVB (International Federation of Gynecologists and Obstetricians recommendations), treated by radiotherapy alone between April 1986 and December 1988 was conducted and the outcomes analysed. The patients were treated using teletherapy 50 Gy/25 fractions, five fractions per week to the whole pelvis together with HDR Cobalt -60 afterloading brachytherapy of 850 cGy/fraction, weekly to point A for 2 fractions. Results: The study covered 141 patients with uterine cervical cancer. The mean age was 50.0 years with a range of 30-78 years. The mean tumor size was 4.1 cm in diameter (range 1-8 cm). Mean follow - up time was 2.94 years (range 1 month-6.92 years). The overall incidence of residual locoregional disease was 3.5%. Residual disease, according to stage IIB, IIIB and IVA was present in 2.78%, 3.37% and 50.0%. It was noted that there was no evidence of residual disease in stage IB and IIA cases. Conclusion: Combined teletherapy along with high dose rate Cobalt -60 brachytherapy of 850 cGy/fraction, weekly to point A for 2 fractions resulted in overall 3.5% residual disease and a 96.5% complete response. The proposed recommendation for improving outcome is initiation of measurements for early detection of disease.

Clinical outcomes of adjuvant radiation therapy and prognostic factors in early stage uterine cervical cancer

  • Kim, Hyun Ju;Rhee, Woo Joong;Choi, Seo Hee;Nam, Eun Ji;Kim, Sang Wun;Kim, Sunghoon;Kim, Young Tae;Kim, Gwi Eon;Kim, Yong Bae
    • Radiation Oncology Journal
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    • v.33 no.2
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    • pp.126-133
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    • 2015
  • Purpose: To evaluate the outcomes of adjuvant radiotherapy (RT) and to analyze prognostic factors of survival in the International Federation of Gynecology and Obstetrics (FIGO) IB-IIA uterine cervical cancer. Materials and Methods: We retrospectively reviewed the medical records of 148 patients with FIGO IB-IIA uterine cervical cancer who underwent surgery followed by adjuvant RT at the Yonsei Cancer Center between June 1997 and December 2011. Adjuvant radiotherapy was delivered to the whole pelvis or an extended field with or without brachytherapy. Among all patients, 57 (38.5%) received adjuvant chemotherapy either concurrently or sequentially. To analyze prognostic factors, we assessed clinicopathologic variables and metabolic parameters measured on preoperative 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT). To evaluate the predictive performance of metabolic parameters, receiver operating characteristic curve analysis was used. Overall survival (OS) and disease-free survival (DFS) were analyzed by the Kaplan-Meier method. Results: The median follow-up period was 63.2 months (range, 2.7 to 206.8 months). Locoregional recurrence alone occurred in 6 patients, while distant metastasis was present in 16 patients, including 2 patients with simultaneous regional failure. The 5-year and 10-year OSs were 87.0% and 85.4%, respectively. The 5-year and 10-year DFSs were 83.8% and 82.5%, respectively. In multivariate analysis, pathologic type and tumor size were shown to be significant prognostic factors associated with both DFS and OS. In subset analysis of 40 patients who underwent preoperative PET/CT, total lesion glycolysis was shown to be the most significant prognostic factor among the clinicopathologic variables and metabolic parameters for DFS. Conclusion: Our results demonstrated that adjuvant RT following hysterectomy effectively improves local control. From the subset analysis of preoperative PET/CT, we can consider that metabolic parameters may hold prognostic significance in early uterine cervical cancer patients. More effective systemic treatments might be needed to reduce distant metastasis in these patients.