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Domestic Clinical Research Trends of Shinbaro Pharmacopuncture: Scoping Review (신바로 약침의 국내 임상 연구 동향: 스코핑 리뷰)

  • Yeongmin Kim;Yunhee Han;Seungkwan Choi;Jungho Jo;Byeonghyeon Jeon;Hyeonjun Woo;Wonbae Ha;Junghan Lee
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.4
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    • pp.125-144
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    • 2023
  • Objectives This study aimed to investigate domestic clinical research trends in Shinbaro pharmacopuncture, identify diseases managed using Shinbaro pharmacopuncture, and suggest the direction for future studies to increase its clinical utilization. Methods This study used five steps proposed by Arksey and O'Malley and the PRISMA-extension for scoping reviews checklist. We examined published literature on Shinbaro pharmacopuncture studies reported until June 5, 2023, in the following eight databases (Research Information Sharing Service, Science ON, Oriental Medicine Advanced Searching Integrated System, KMBASE, The Society of Internal Korean Medicine, PubMed, EMBASE, and the Cochrane Library). The search terms used were 'Shinbaro' or 'Sinbaro'. Results A total of 47 studies were included in our analysis. Of these, 37 (78.7%) were interference time series studies. Shinbaro pharmacopuncture was the most frequently used treatment for lumbosacral disease (n=15). In the facial area, ST4 and ST6 were used in five out of six studies, and in the shoulder area, TE14 and LI15 were used in all studies. Nine of the 15 studies in the lumbosacral area used the EX-B2. The other parts mostly used the pressure points. Compared to other pharmacopuncture methods, the treatment effect was similar to that of bee venom, and faster than that of jungsongouhyul. Conclusions This is the first scoping review of Shinbaro pharmacopuncture therapy in South Korea. Studies with a high level of evidence based on sole treatment, large capacities, and standardization of Shinbaro pharmacopuncture need to be conducted to increase its clinical utilization.

Scientifically Gifted Students' Perception of the Learning Support System based on Korea Science Academy Survey (과학영재학교의 학습 지원 체제 유용성에 대한 학생들의 인식 : 한국과학영재학교를 중심으로)

  • Bae, Sae-Byok;Kim, Kyoung-Dae;Kang, Soon-Min;Yune, So-Jung
    • Journal of The Korean Association For Science Education
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    • v.29 no.5
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    • pp.552-563
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    • 2009
  • The purpose of this study is to investigate the students' perception of the learning support system of Korea Science Academy and to propose improvements to it. The impact of the science learning support system on 129 gifted students in Korea Science Academy (KSA) was estimated by using Likert-type items and the multiple-choice method approach for more comprehensive evaluation. The results of our investigation are as follows: First, the learning support system of KSA appears globally useful to the students. The list of educational usefulness to the students comprises, in the decreasing order of utility, classroom work, Internet, lab activities, reading rooms, library, research meetings and clubs, academic advisors (AA), SAF (Science Academy Fair), e-learning system, and finally colloquia by invited lecturers. Second, what the gifted students hope for in the realm of learning support from KSA are learning guides by subject teachers, presentation skill program, the constructions of on/off-line learning communities, etc. It seems that the results of this study would be helpful in improving the learning support system, and will provide useful information for planning the direction of future science-gifted education programs at the high-school level.

Exploring ESG Activities Using Text Analysis of ESG Reports -A Case of Chinese Listed Manufacturing Companies- (ESG 보고서의 텍스트 분석을 이용한 ESG 활동 탐색 -중국 상장 제조 기업을 대상으로-)

  • Wung Chul Jin;Seung Ik Baek;Yu Feng Sun;Xiang Dan Jin
    • Journal of Service Research and Studies
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    • v.14 no.2
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    • pp.18-36
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    • 2024
  • As interest in ESG has been increased, it is easy to find papers that empirically study that a company's ESG activities have a positive impact on the company's performance. However, research on what ESG activities companies should actually engage in is relatively lacking. Accordingly, this study systematically classifies ESG activities of companies and seeks to provide insight to companies seeking to plan new ESG activities. This study analyzes how Chinese manufacturing companies perform ESG activities based on their dynamic capabilities in the global economy and how they differ in their activities. This study used the ESG annual reports of 151 Chinese manufacturing listed companies on the Shanghai & Shenzhen Stock Exchange and ESG indicators of China Securities Index Company (CSI) as data. This study focused on the following three research questions. The first is to determine whether there are any differences in ESG activities between companies with high ESG scores (TOP-25) and companies with low ESG scores (BOT-25), and the second is to determine whether there are any changes in ESG activities over a 10-year period (2010-2019), focusing only on companies with high ESG scores. The results showed that there was a significant difference in ESG activities between high and low ESG scorers, while tracking the year-to-year change in activities of the top-25 companies did not show any difference in ESG activities. In the third study, social network analysis was conducted on the keywords of E/S/G. Through the co-concurrence matrix technique, we visualized the ESG activities of companies in a four-quadrant graph and set the direction for ESG activities based on this.

A study on the design of an efficient hardware and software mixed-mode image processing system for detecting patient movement (환자움직임 감지를 위한 효율적인 하드웨어 및 소프트웨어 혼성 모드 영상처리시스템설계에 관한 연구)

  • Seungmin Jung;Euisung Jung;Myeonghwan Kim
    • Journal of Internet Computing and Services
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    • v.25 no.1
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    • pp.29-37
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    • 2024
  • In this paper, we propose an efficient image processing system to detect and track the movement of specific objects such as patients. The proposed system extracts the outline area of an object from a binarized difference image by applying a thinning algorithm that enables more precise detection compared to previous algorithms and is advantageous for mixed-mode design. The binarization and thinning steps, which require a lot of computation, are designed based on RTL (Register Transfer Level) and replaced with optimized hardware blocks through logic circuit synthesis. The designed binarization and thinning block was synthesized into a logic circuit using the standard 180n CMOS library and its operation was verified through simulation. To compare software-based performance, performance analysis of binary and thinning operations was also performed by applying sample images with 640 × 360 resolution in a 32-bit FPGA embedded system environment. As a result of verification, it was confirmed that the mixed-mode design can improve the processing speed by 93.8% in the binary and thinning stages compared to the previous software-only processing speed. The proposed mixed-mode system for object recognition is expected to be able to efficiently monitor patient movements even in an edge computing environment where artificial intelligence networks are not applied.

Proximal Policy Optimization Reinforcement Learning based Optimal Path Planning Study of Surion Agent against Enemy Air Defense Threats (근접 정책 최적화 기반의 적 대공 방어 위협하 수리온 에이전트의 최적 기동경로 도출 연구)

  • Jae-Hwan Kim;Jong-Hwan Kim
    • Journal of the Korea Society for Simulation
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    • v.33 no.2
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    • pp.37-44
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    • 2024
  • The Korean Helicopter Development Program has successfully introduced the Surion helicopter, a versatile multi-domain operational aircraft that replaces the aging UH-1 and 500MD helicopters. Specifically designed for maneuverability, the Surion plays a crucial role in low-altitude tactical maneuvers for personnel transportation and specific missions, emphasizing the helicopter's survivability. Despite the significance of its low-altitude tactical maneuver capability, there is a notable gap in research focusing on multi-mission tactical maneuvers that consider the risk factors associated with deploying the Surion in the presence of enemy air defenses. This study addresses this gap by exploring a method to enhance the Surion's low-altitude maneuvering paths, incorporating information about enemy air defenses. Leveraging the Proximal Policy Optimization (PPO) algorithm, a reinforcement learning-based approach, the research aims to optimize the helicopter's path planning. Visualized experiments were conducted using a Surion model implemented in the Unity environment and ML-Agents library. The proposed method resulted in a rapid and stable policy convergence for generating optimal maneuvering paths for the Surion. The experiments, based on two key criteria, "operation time" and "minimum damage," revealed distinct optimal paths. This divergence suggests the potential for effective tactical maneuvers in low-altitude situations, considering the risk factors associated with enemy air defenses. Importantly, the Surion's capability for remote control in all directions enhances its adaptability in complex operational environments.

Enhancing Global Research Visibility of Faculty Staffs by the Academic libraries in Public Universities in South East, Nigeria

  • Francisca C. MBAGWU;Judith S. NSE;Jacintha EZE;Ijeoma Irene BERNARD
    • International Journal of Knowledge Content Development & Technology
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    • v.14 no.2
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    • pp.29-46
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    • 2024
  • Academic libraries are at the forefront of supporting their parent institutions in teaching and learning, research activities, and community services for the students and faculty members, but, the researchers observed that some of the research emanating from faculty members in academic institutions particularly universities remains largely unknown, unrecognized and invisible on the global scene. This present paper is therefore a modest attempt towards addressing the issue of enhancing the faculty research visibility in the institutions of higher learning by the academic libraries. It also examines the extent academic libraries in public universities in Nigeria use research visibility channels to increase the global visibility of their faculty members. Difficulties encountered by librarians and ways of tackling the visibility of the faculty were also examined. A descriptive survey research design was adopted and the population consisted of all the 162 librarians in public universities in South-East (S.E), Nigeria. Telephone calls and Online Questionnaire were used for data collection. The number of librarians was obtained through phone calls from the Heads of each of the Libraries. The Online Questionnaire was submitted to the WhatsApp platforms of librarians in Nigeria- Academic and Research Libraries (ARL) and Chartered Librarians in Nigeria Connect (CLN-Connect). The questionnaire was structured in such a way that only the Librarians in Public universities in the S.E. Nigeria will respond to it. At the end of the day only 120 librarians responded, at a response rate of 74%. The study was analysed using tables, percentages and charts. The study recommended that librarians who are unaware of RVCs and its utilization should go for training to acquire the knowledge that will enable them enhance the global visibility of faculty staff, Management of Public universities in S.E, Nigeria should in addition to addressing copyright issues by the use of disclaimer notices and creative common licensing and provision of infrastructural facilities e.g. steady power supply, High power brand Internet connectivity, establishment of an Institutional Repository, etc, also should mandate the faculty staff to release their productive work to the library for onward submission to the RVCs platforms for enhancement of their global visibility.

Efficacy and Safety of Combination Treatment of Traditional Korean Medicine after Gastric Cancer Surgery: A Systematic Review and Meta-analysis Protocol (위암 수술 후 항암치료를 병행한 한의치료의 유효성 및 안전성: 체계적 문헌고찰 및 메타분석 프로토콜)

  • Jong-hee Kim;Eunbin Kwag;So-jung Park;Donghyun Kim;Soodam Kim;Jihye Park;Hwa-seung Yoo
    • Herbal Formula Science
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    • v.31 no.4
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    • pp.361-371
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    • 2023
  • Objectives : Gastric cancer is a malignant tumor of the digestive tract that not only has a high mortality rate, but also affects quality of life. In Traditional Korean Medicine, acupuncture and herbal medicines can increase the survival rate for Gastric cancer and improve the quality of life. Traditional Korean Medicine treatment played an important role when used alone or in combination with chemotherapy. However, there is still insufficient evidence to support the efficacy and safety of Traditional Korean Medicine in patients undergoing chemotherapy after surgery. Therefore, the purpose of this study is to systematically evaluate the effect of oriental medicine treatment on patients as a complementary therapy for Gastric cancer. Methods : 2 researchers will search using EMBASE, Pubmed, CNKI, Cochrane Library, CiNii, KMBASE, KISS, OASIS, RISS, ScienceON. The search period of the database is from inception until June 2022. This study will include a randomized controlled trial of GC for acupuncture and herbal treatment. Primary outcomes include anti-cancer effects. Secondary outcomes evaluate survival rates and improvements in quality of life. The data uses Review Manager Software 5.4. Results : This study will provide a systematic evaluation by synthesizing the anti-cancer effect, survival rate and quality of life of Gastric cancer when Traditional Korean Medicine is combined with chemotherapy. Conclusion : The conclusion of this study will provide a basis for determining whether Traditional Korean Medicine treatment for Gastric cancer treatment is an effective and safe treatment method in clinical practice.

MRI Assessment of Complete Response to Preoperative Chemoradiation Therapy for Rectal Cancer: 2020 Guide for Practice from the Korean Society of Abdominal Radiology

  • Seong Ho Park;Seung Hyun Cho;Sang Hyun Choi;Jong Keon Jang;Min Ju Kim;Seung Ho Kim;Joon Seok Lim;Sung Kyoung Moon;Ji Hoon Park;Nieun Seo;Korean Society of Abdominal Radiology Study Group for Rectal Cancer
    • Korean Journal of Radiology
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    • v.21 no.7
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    • pp.812-828
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    • 2020
  • Objective: To provide an evidence-based guide for the MRI interpretation of complete tumor response after neoadjuvant chemoradiation therapy (CRT) for rectal cancer using visual assessment on T2-weighted imaging (T2) and diffusion-weighted imaging (DWI). Materials and Methods: PubMed MEDLINE, EMBASE, and Cochrane Library were searched on November 28, 2019 to identify articles on the following issues: 1) sensitivity and specificity of T2 or DWI for diagnosing pathologic complete response (pCR) and the criteria for MRI diagnosis; 2) MRI alone vs. MRI combined with other test(s) in sensitivity and specificity for pCR; and 3) tests to select patients for the watch-and-wait management. Eligible articles were selected according to meticulous criteria and were synthesized. Results: Of 1615 article candidates, 55 eligible articles (for all three issues combined) were identified. Combined T2 and DWI performed better than T2 alone, with a meta-analytic summary sensitivity of 0.62 (95% confidence interval [CI], 0.43-0.77; I2 = 80.60) and summary specificity of 0.89 (95% CI, 0.80-0.94; I2 = 92.61) for diagnosing pCR. The criteria for the complete response on T2 in most studies had the commonality of remarkable tumor decrease to the absence of mass-like or nodular intermediate signal, although somewhat varied, as follows: (near) normalization of the wall; regular, thin, hypointense scar in the luminal side with (near) normal-appearance or homogeneous intermediate signal in the underlying wall; and hypointense thickening of the wall. The criteria on DWI were the absence of a hyperintense signal at high b-value (≥ 800 sec/mm2) in most studies. The specific algorithm to combine T2 and DWI was obscure in half of the studies. MRI combined with endoscopy was the most utilized means to select patients for the watch-and-wait management despite a lack of strong evidence to guide and support a multi-test approach. Conclusion: This systematic review and meta-analysis provide an evidence-based practical guide for MRI assessment of complete tumor response after CRT for rectal cancer.

2021 Korean Society of Gastrointestinal Endoscopy Clinical Practice Guidelines for Endoscopic Sedation

  • Hong Jun Park;Byung-Wook Kim;Jun Kyu Lee;Yehyun Park;Jin Myung Park;Jun Yong Bae;Seung Young Seo;Jae Min Lee;Jee Hyun Lee;Hyung Ku Chon;Jun-Won Chung;Hyun Ho Choi;Myung Ha Kim;Dong Ah Park;Jae Hung Jung;Joo Young Cho;Endoscopic Sedation Committee of Korean Society of Gastrointestinal Endoscopy
    • Clinical Endoscopy
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    • v.55 no.2
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    • pp.167-182
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    • 2022
  • Sedation can resolve anxiety and fear in patients undergoing endoscopy. The use of sedatives has increased in Korea. Appropriate sedation is a state in which the patient feels subjectively comfortable while maintaining the airway reflex for stable spontaneous breathing. The patient should maintain a state of consciousness to the extent that he or she can cooperate with the needs of the medical staff. Despite its benefits, endoscopic sedation has been associated with cardiopulmonary complications. Cardiopulmonary complications are usually temporary. Most patients recover without sequelae. However, they may progress to serious complications, such as cardiovascular collapse. Therefore, it is essential to screen high-risk patients before sedation and reduce complications by meticulous monitoring. Additionally, physicians should be familiar with the management of emergencies. The first Korean clinical practice guideline for endoscopic sedation was developed based on previous worldwide guidelines for endoscopic sedation using an adaptation process. The guideline consists of nine recommendations based on a critical review of currently available data and expert consensus when the guideline was drafted. These guidelines should provide clinicians, nurses, medical school students, and policy makers with information on how to perform endoscopic sedation with minimal risk.

Identification and molecular characterization of the chitinase gene, EaChi, from the midgut of the earthworm, Eisenia andrei (붉은줄지렁이 (Eisenia andrei) 중장에서 발현되는 chitinase 유전자, EaChi의 동정 및 분자생물학적 특성에 관한 연구)

  • Tak, Eun Sik;Kim, Dae hwan;Lee, Myung Sik;Ahn, Chi Hyun;Park, Soon Cheol
    • Journal of the Korea Organic Resources Recycling Association
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    • v.18 no.3
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    • pp.31-37
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    • 2010
  • Chitinases (EC 3.2.1.14) hydrolyze the ${\beta}$-1,4-linkages in chitin, the second most abundant polymer of N-acetyl-${\beta}$-D-glucosamine which is a structural component of protective biological matrices such as fungal cell walls and insect exoskeletons. The glycosyl hydrolases 18 family including chitinases is an ancient gene family widely expressed in archea, prokaryotes and eukaryotes. Since earthworms live in the soil with a lot of microbial activities and fungi are supposed to be a major component of the diet of earthworm, it has been reported that there would be appropriate immune system to protect themselves from microorganisms attacks. In this study, the novel chitinase, EaChi, from the midgut of earthworm, Eisenia andrei, were identified and characterized. To obtain full-length cDNA sequence of chitinase, RT-PCR and RACE-PCR analyses were carried out by using the previously identified EST sequence amongst cDNA library established from the midgut of E. andrei. EaChi, a partial chitinase gene, was composed of 927 nucleotides encoding 309 amino acids. By the multiple sequence alignments of amino acids with other different species, it was revealed that EaCHI is a member of glycosyl hydrolases 18 family, which has two highly conserved domains, substrate binding and catalytic domain.