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The Effects of Inspiratory Pause on Airway Pressure and Gas Exchange under Same I:E ratio in Volume-controlled Ventilation (Volume-Controlled Mode의 기계환기시 동일환 I:E Ratio하에서 Inspiratory Pause가 기도압 몇 가스교환에 미치는 영향)

  • Choi, Won-Jun;Jung, Sung-Han;Lee, Jeong-A;Choe, Kang-Hyeon
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.5
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    • pp.1022-1030
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    • 1998
  • Background : In volume-controlled ventilation, the use of inspiratory pause increases the inspiratory time and thus increases mean airway pressure and improves ventilation. But under the same I : E ratio, the effects of inspiratory pause on mean airway pressure and gas exchange are not certain. Moreover, the effects may be different according to the resistance of respiratory system. So we studied the effects of inspiratory pause on airway pressure and gas exchange under the same I : E ratio in volume-controlled ventilation. Methods: Airway pressure and arterial blood gases were evaluated in 12 patients under volume-controlled mechanical ventilation with and without inspiratory pause time 5%. The I : E ratio of 1 : 3, $FiO_2$, tidal volume, respiratory rate, and PEEP were kept constant. Results: $PaCO_2$ with inspiratory pause was lower than without inspiratory pause ($38.6{\pm}7.4$ mmHg vs. $41.0{\pm}7.7$ mmHg. p<0.01). P(A-a)$O_2$ was not different between ventilation with and without inspiratory pause $185.3{\pm}86.5$ mmHg vs. $184.9{\pm}84.9$ mmHg, p=0.766). Mean airway pressure with inspiratory pause was higher than without inspiratory pause ($9.7{\pm}4.0\;cmH_2O$ vs. $8.8{\pm}4.0\;cmH_2O$, p<0.01). The resistance of respiratory system inversely correlated with the pressure difference between plateau pressure with pause and peak inspiratory pressure without pause (r=-0.777, p<0.l), but positively correlated with the pressure difference between peak inspiratory pressure with pause and peak inspiratory pressure without pause (r=0.811, p<0.01). Thus the amount of increase in mean airway pressure with pause positively correlated with the resistance of respiratory system (r=0.681, p<0.05). However, the change of mean airway pressure did not correlated with the change of $PaCO_2$. Conclusion: In volume-controlled ventilation under the same I : E ratio of 1 : 3, inspiratory pause time of 5% increases mean airway pressure and improves ventilation. Although the higher resistance of respiratory system, the more increased mean airway pressure, the increase in mean airway pressure did not correlated with the change in $PaCO_2$.

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EFFECTS OF SUBINHIBITORY CONCENTRATIONS OF ANTIMICROBIAL AGENTS ON CELL SURFACE PROPERTIES AND VIRULENCE FACTORS OF MUTANS STREPTOCOCCI (아저해농도(亞沮害濃度)의 항균물질이 mutans streptococci의 세포표면성질과 독력인자에 미치는 영향)

  • Kim, Young-Jae;Hahn, Se-Hyun;Lee, Sang-Hoon;Jang, Ki-Taeg;Kim, Chol-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.31 no.4
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    • pp.605-616
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    • 2004
  • Subinhibitory concentrations (sub-MICs) refer to concentrations below minimum inhibitory concentrations (MICs). The antimicrobial agents may be present at relatively high concentration, at least higher than bacterial MIC and thereafter be deserted off a surface and function at sub-MICs, perhaps by interfering with bacterial metabolism. Consequently, the aim of this study was to determine the effects of growth, in the presence of sub-MICs of antimicrobial agents, on the cell surface properties and virulence factors of mutans streptococci and to investigate the efficacy of a chemical approach in vitro. Streptococcus mutans Ingbritt and Streptococcus sobrinus 6715-7 were used. Eight antimicrobial agents (Sanguinaria extract;SG, Chlorhexidine digluconate;CHX, Fluoride;F, Propolis;PP, Hydrogen peroxide;HP, Triclosan;TC, Sodium dodecyl sulfate;SDS Cetylpyridinium chloride; CC) were diluted serially in broth to determine MICs and to compare the growth rate, acid production, hydrophobicity, adhesion activity to saliva coated hydroxyapatite, glucan synthesis and cellular aggregation of experiment groups (in the presence of sub-MICs) with those of control (in the absence of antimicrobial agents). Sub-MICs of antimicrobial agents affected the growth of cells, hydrophobicity, and adhesion of bacteria to saliva coated hydroxyapatite and glucan synthesis. They also resulted in a significant reduction in pH after 12 hours (p<0.05). By cells pretreated with proteinase K, either the aggregation induced by antimicrobial agents was completely inhibited or the aggregation titers were markedly increased. According to the results of the present study, each antimicrobial agent at sub-MICs could affect similar as its known action mechanism and could continually inhibit cariogenic bacteria at such concentrations. Thus, the use of these antimicrobial agents would be one of the effective methods to prevent dental caries.

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A COMPARISON OF THE SEDATIVE EFFECT ON CHLORAL HYDRATE DOSAGE IN THE SEDATION OF THE PEDIATRIC DENTAL PATIENTS (소아환자 진정요법에서 chloral hydrate의 용량에 따른 진정효과에 관한 연구)

  • Rho, Seung-Chul;Kim, Young-Jae;Jang, Ki-Taeg;Hahn, Se-Hyun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.3
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    • pp.517-524
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    • 2005
  • Despite the widespread use of chloral hydrate with hydroxyzine in the sedation of children, there is little agreement among pediatric dentists regarding its therapeutic dosage for the management of very uncooperative young children. Also, increasing concern has been raised with respect to its frequent failure to provide adequate levels of sedation when used according to the manufacturer's recommended dosage. Therefore, there has been many suggestions with respect to sedative effectiveness and safety of varying drug dosage, and some pediatric dental articles have advocated dosages exceeding manufacturer's recommendations. This study was performed to compare the effectiveness and safety in behavior management of the manufacturer's recommended dose of chloral hydrate(50mg/kg) with those of a higher dose(70mg/kg) used together with hydroxyzine(2mg/kg) and nitrous oxide(50%) when young children were sedated for dental treatment. The following results were obtained; 1. II group(70mg/kg) displayed higher mean score compared to I group(50mg/kg) with regard to the degree of sleep, crying, movement and overall behavior. The difference was statistically significant(p<0.05). 2. In comparison of success rates for sedation between the two groups, I group and II group showed 38.7% and 71.0% success rates respectively. An analysis of variance was statistically significant(p<0.05). 3. Comparing the occurrence rate hypoxia between the two groups, there were 22.6% and 19.4% occurrence of hypoxia in I group and II group. An analysis of variance was not statistically significant(p>0.05).

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Temporal and Spatial Characteristics of Sediment Yields from the Chungju Dam Upstream Watershed (충주댐 상류유역의 유사 발생에 대한 시공간적인 특성)

  • Kim, Chul-Gyum;Lee, Jeong-Eun;Kim, Nam-Won
    • Journal of Korea Water Resources Association
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    • v.40 no.11
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    • pp.887-898
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    • 2007
  • A physically based semi-distributed model, SWAT was applied to the Chungju Dam upstream watershed in order to investigate the spatial and temporal characteristics of watershed sediment yields. For this, general features of the SWAT and sediment simulation algorithm within the model were described briefly, and watershed sediment modeling system was constructed after calibration and validation of parameters related to the runoff and sediment. With this modeling system, temporal and spatial variation of soil loss and sediment yields according to watershed scales, land uses, and reaches was analyzed. Sediment yield rates with drainage areas resulted in $0.5{\sim}0.6ton/ha/yr$ excluding some upstream sub-watersheds and showed around 0.51 ton/ha/yr above the areas of $1,000km^2$. Annual average soil loss according to land use represented the higher values in upland areas, but relatively lower in paddy and forest areas which were similar to the previous results from other researchers. Among the upstream reaches, Pyeongchanggang and Jucheongang showed higher sediment yields which was thought to be caused by larger area and higher fraction of upland than other upstream sub-areas. Monthly sediment yields at the main outlet showed same trend with seasonal rainfall distribution, that is, approximately 62% of annual yield was generated during July to August and the amount was about 208 ton/yr. From the results, we could obtain the uniform value of sediment yield rate and could roughly evaluate the effect of soil loss with land uses, and also could analyze the temporal and spatial characteristics of sediment yields from each reach and monthly variation for the Chungju Dam upstream watershed.

Estimation of Optimum Raate of Cattle Slurry Application for Forage Production Using Idled Rice Paddy I. The Effect of cattle slurry application on annual dry matter yield in reed canarygrass. (유휴 논토양에서 조사료 생산을 위한 적정 액상구비 시용수준의 추정 I. 액상구비의 시용이 Reed Canarygrass의 연 건물수량에 미치는 영향)

  • 이주삼;조익환;김성규;안종호
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.14 no.1
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    • pp.50-56
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    • 1994
  • This study was investigated for the purposes of securing forage resource using idled rice paddy recently increased in accordance to a current trend of farm products' liberalization and also of presevation of environment by using cattle sluny as liquid manure, which is seriously increasing these days. In this study, mean annual dry matter yield and its seasonal variation with reed canarygrass, and a optimum rate of cattle sluny application were investigated. The results are as follows: 1. According to the conditions of cutting frequencies(3, 4 and 5 cutting per year), mean annual dry matter yield was recorded from 8.9 tons to 10.9 tons per hectare and was the highest at 3 cutting frequency. 2. The use of cattle sluny with the levels of between 300 and 360 kg N per hectare showed a significantly higher mean annual dry matter yield than that of the control (non-fertilization). 3. The treatments with 3 and 4 cutting frequencies(90 kg Nhdyear, 120 kg Nhdyear) recorded higher dry matter yields than the control of the former level by 1.23 tons and 2.34 tons respectively and in the treatment of 5 cutting frequency, the second level with cattle sluny of 300 kg Nhdyear showed an increased dry matter yield of 2.11 tons compared to the former level(l50 kg Nhdyear). With regards to nitrogen efficiency, one kg of nitrogen is applied to 13.7, 19.4 and 14.1 kg of dry matter yields in the conditions of 3, 4 and 5 cutting frequencies respectively. 4. In view of seasonal variance of annual dry matter yield, the second cut in 3 cutting frequency, the third cut in 4 cutting frequency and the third in 5 cutting frequency showed the highest ratio as 42, 37 and 32% respectively compared to the total. 5. Under the conditions of this study, the 'Input-Output curve' from 5 cutting frequency was the closest to sigmaformed process(i=0.9993) of various cutting frequencies, and the maximum marginal yield in the treatment was obtained at the level of 250 kg Nha with cattle sluny. The economic level of cattle sluny was between 371.0 and 402.2 kg N and the highest dry matter yield was obtained at 489.3 kg Mdyear in the same treatment

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Long-term Climate Change Research Facility for Trees: CO2-Enriched Open Top Chamber System (수목의 장기 기후변화 연구시설: CO2 폭로용 상부 개방형 온실)

  • Lee, Jae-Cheon;Kim, Du-Hyun;Kim, Gil-Nam;Kim, Pan-Gi;Han, Sim-Hee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.14 no.1
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    • pp.19-27
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    • 2012
  • The open-top chamber (OTC) system is designed for long term studies on the climate change impact on the major tree species and their community in Korea. In Korea Forest Research Institute (KFRI), the modified OTC system has been operating since September 2009. The OTC facility consists of six decagon chambers (10 meters in diameter by 7 meters high) with controlled gas concentration. In each chamber, a series of vertical vent pipes are installed to disperse carbon dioxide or normal air into the center of the chamber. The OTC is equipped with remote controlled computer system in order to maintain a stable and elevated concentration of carbon dioxide in the chamber throughout the experimental period. The experiment consisted of 4 treatments: two elevated $CO_2$ levels ($1.4{\times}$ and $1.8{\times}$ ambient $CO_2$) and two controls (inside and outdoors of the OTC). Average operational rate was the lowest (94.2%) in June 2010 but increased to 98% in July 2010 and was 100% during January to December 2011. In 2010~2011, $CO_2$ concentrations inside the OTCs reached the target programmed values, and have been maintained stable in 2011. In 2011, $CO_2$ concentrations of 106%, 100% and 94% of target values has been recorded in control OTC, $1.4{\times}$ $CO_2$-enriched OTC and $1.8{\times}$ $CO_2$-enriched OTC, respectively. With all OTC chambers, the difference between outside and inside temperatures was the highest ($1.2{\sim}2.0^{\circ}C$) at 10 am to 2 pm. Temperature difference between six OTC chambers was not detected. The relative humidity inside and outside the chambers was the same, with minor variations (0~1%). The system required the highest amount of $CO_2$ for operation in June, and consumed 11.33 and 17.04 ton in June 2010 and 2011, respectively.

Morbidity of Laparoscopic Assisted Gastrectomy for Early Gastric Cancer (조기 위암에서 복강경 보조 하 위 절제술 후 합병증 발생)

  • Choi, Ji-Eun;Jeong, Oh;Yook, Jeong-Hwan;Kim, Kab-Jung;Lim, Jung-Tack;Oh, Sung-Tae;Park, Gun-Choon;Kim, Byung-Sik
    • Journal of Gastric Cancer
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    • v.7 no.3
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    • pp.152-159
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    • 2007
  • Purpose: Recently, the use of laparoscopic assisted gastrectomy for early gastric cancer has been on the increase and the procedure has been quickly adopted by clincians. However, there are few reports regarding the safety and risk of this type of surgery. The aim of this study is to evaluate the morbidity and to verify the safety of laparoscopic assisted gastrectomy for early gastric cancer. Materials and Methods: A total of 376 patients that had undergone laparoscopic assisted gastrectomy for early gastric cancer between April 2004 and December 2006 were reviewed retrospectively. The clinicopathological characteristics, operative complications, and factors related to complications were evaluated. Results: The overall operative morbidity and mortality rates were 10.6% and 0%, intraoperative morbidity was 1.1% (4 of 376 patients) and post operative morbidity was 9.6% (36 of 376 patients). Most complications required no surgery except for an intestinal obstruction in two cases. Multivariate analysis of risk factors related to operative morbidity determined that age was an independent factor associated with morbidity (P=0.021). Conclusion: The complication rate of laparoscopic assisted gastrectomy is low and most complications can be managed by conservative methods rather than with surgery. There were no specific predicting factors for complications except old age. Laparoscopy is a technically feasible and acceptable surgical modality for early gastric cancer.

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Evaluation of Nutrients Removal using Pyrolyzed Oyster Shells (소성온도에 따른 굴 패각의 영양염 제거 성능 평가)

  • Jeong, Ilwon;Woo, Hee-eun;Lee, In-Cheol;Kim, Jinsoo;Kim, Kyunghoi
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.7
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    • pp.906-913
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    • 2019
  • To evaluate the removal performance of PO4-P and NH3-N, laboratory experiments were conducted by filling a container with oyster shells, pyrolyzed at 100℃ (POS100), 600℃ (POS600) and 800℃ (POS800), and passing artificial wastewaters through the container. The pH in the ef luent was found to increase due to CaO eluted from oyster shell. Removal amounts of PO4-P of ~23.1 mg/kg, 16.1 mg/kg, and 15.9 mg/kg were obtained when POS100, POS600, and POS800, respectively, were used; therefore, the highest PO4-P removal amount was obtained when POS100 was used. It is considered that Ca and dolomite in the oyster shells adsorbed and precipitated PO4-P. Removal amounts of NH3-N were of ~3.56 mg/kg, 5.72 mg/kg, and 3.97 mg/kg were obtained when POS100, POS600, and POS800, respectively, were used The low removal rate for NH3-N is probably due to unstable nitrification, use of sealed containers, and the effect of NH3-N being converted to NH4+ upon increasing pH. Based on these results, pyrolyzed oyster shell is expected to promote changes in PO4-P and NH3-N concentrations through chemical reactions. These results can also be used for basic research in the development of wastewater treatment.

The Evaluation of Physical Environmental Factors in Urban Parks for Healthy City - Focus on Seoul - (건강증진을 위한 도시공원의 물리적 환경요소 평가 - 서울시를 대상으로 -)

  • Chae, Jin-Hae;Kim, Won-Ju
    • Journal of the Korean Institute of Landscape Architecture
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    • v.48 no.4
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    • pp.29-40
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    • 2020
  • This study quantitatively and qualitatively analyzes the physical environment for health promotion in urban parks by indicators that were selected in consideration of overseas cases and previous studies. To evenly distribute the areas to be evaluated by region, Seodaemun Independence Park, Hongneung Park, Gocheok Park, Sillim Park, Cheongdam Park, Gaepo Park, and Sungin Park were selected among the old neighborhood parks already established in Seoul. The evaluation indicators consist of quantitative indicators (12 factors classified into the three categories of the surrounding environment, the park characteristics, and the park facilities) and qualitative indicators (14 factors classified according to the five categories of accessibility, safety, convenience, activities, and amenities). These indicators were selected after conducting advisory meetings with experts in the field. The physical environment perception factors were evaluated by experts and investigators by field inspections and were rated on a three-point scale (high, medium, low). According to the results of the analysis, first, not only were exercise facilities and trails, but also various factors which support health activities, such as rest areas, leisure spots, and cultural facilities, as well as accessibility, cleanliness, and drinking water facilities are important indicators for health promotion. Second, even if the requirements are met for quantitative factors, several inconveniences hinder the actual implementation or use in the qualitative evaluation. Thus, both quantitative and qualitative evaluations must be simultaneously performed for the proper judging of the physical environment of a park. Third, upon conducting a qualitative evaluation of the physical environmental factors, score differences depended on the evaluated categories in each park. These differences show that indirect indicators, such as accessibility, safety, and facility convenience are insufficiently equipped compared to direct indicators, such as activity, which includes exercise facilities and fitness centers for health promotion. As the utilization rate of parks is increasing due to COVID-19, more efforts should be made to improve park services in the post-corona era. To promote such services, it is necessary to regularly evaluate parks based on both quantitative and qualitative indicators and to contemplate services not only through direct factors but also indirect factors and security measures.

Automatic Text Extraction from News Video using Morphology and Text Shape (형태학과 문자의 모양을 이용한 뉴스 비디오에서의 자동 문자 추출)

  • Jang, In-Young;Ko, Byoung-Chul;Kim, Kil-Cheon;Byun, Hye-Ran
    • Journal of KIISE:Computing Practices and Letters
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    • v.8 no.4
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    • pp.479-488
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    • 2002
  • In recent years the amount of digital video used has risen dramatically to keep pace with the increasing use of the Internet and consequently an automated method is needed for indexing digital video databases. Textual information, both superimposed and embedded scene texts, appearing in a digital video can be a crucial clue for helping the video indexing. In this paper, a new method is presented to extract both superimposed and embedded scene texts in a freeze-frame of news video. The algorithm is summarized in the following three steps. For the first step, a color image is converted into a gray-level image and applies contrast stretching to enhance the contrast of the input image. Then, a modified local adaptive thresholding is applied to the contrast-stretched image. The second step is divided into three processes: eliminating text-like components by applying erosion, dilation, and (OpenClose+CloseOpen)/2 morphological operations, maintaining text components using (OpenClose+CloseOpen)/2 operation with a new Geo-correction method, and subtracting two result images for eliminating false-positive components further. In the third filtering step, the characteristics of each component such as the ratio of the number of pixels in each candidate component to the number of its boundary pixels and the ratio of the minor to the major axis of each bounding box are used. Acceptable results have been obtained using the proposed method on 300 news images with a recognition rate of 93.6%. Also, my method indicates a good performance on all the various kinds of images by adjusting the size of the structuring element.