• 대한한방내과학회지
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• 제40권6호
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• pp.1063-1080
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• 2019

Objectives: With the aging of the population, the incidence of a variety of diseases is increasing. Cerebrovascular disease is a major cause of mortality worldwide and therefore requires timely treatment and management. We aimed to evaluate the clinical effectiveness of herbal medicines in treating cerebrovascular disease by screening the most frequently prescribed herbal medicines and analyzing the clinical data of patients with cerebrovascular disease taking these medicines. Methods: In this retrospective study, we analyzed the electronic medical records of patients with cerebrovascular disease who received herbal medication at the Pusan National University Korean Medical Hospital from 10 March 2010 to 31 March 2017. The inclusion criteria were as follows: diagnosis of cerebrovascular disease, use of frequently prescribed herbal medicines, available records of laboratory tests and functional evaluation that was conducted within two weeks before and after admission and discharge, and herbal medicine usage exceeding half the period of hospitalization. Results: Of the total patients with cerebrovascular disease, the number of patients analyzed in this study was 49. There were some changes in the various variables examined after frequently used herbal medicines had been taken, such as complete blood count, liver function test, lipid test, and functional evaluation. No serious adverse events related to herbal medicine were found in this study. Conclusions: We concluded that herbal medicines frequently used for cerebrovascular disease may have some clinical effectiveness. However, because of the retrospective nature of this study and only one hospital involved, the generalizability of our findings is limited.

• 방사선산업학회지
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• 제7권2_3호
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• pp.221-224
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• 2013

RI-Biomics is a new compound word of radiation technology and Biomics related to the study of life. RI-Biomics is high radiation fusion technology by combining evaluation of pharmacokinetics in vivo (RI-ADME) of new drugs and medical materials using radioisotope and molecular imaging technology using nuclear medicine equipments. RI-Biomics fields are emerging with the increasing usage of radioisotopes (RI). In this paper, we investigated the latest trends of radioisotope using in RI-Biomics fields. The representative radioisotopes are $^{14}C$, $^3H$ and $^{32}P$ for the optimization and the selection of candidates in the development process of new drugs among the RI-Biomics fields. As shown in the status of accumulated income of radioisotopes, using amounts of radioisotopes are showing a tendency to increase every year. $^{14}C$ is 61.6% increase of accumulated income growth rate and $^3H$ increased by 58.8% and $^{32}P$ increased by 33.9% in 2012 compared to 2007. These isotopes are used in a variety of fields as using of $^{14}C$ for microdosing test, development of [$^3H$]cholesterol absorption inhibitors, study of [$^{131}I$]pyronaridine tetraphosphate for malaria therapy. These are going on in vivo test sucessfully. So, clinical research step is expected to begin soon. Therefore, usages of radioisotopes are necessary and need for the evaluation of pharmacokinetics, optimization and the selection of new drug candidates in the development process of new drugs among the RI-Biomics fields. So, using of radioisotopes is predict to increase continuously except for primarily used $^{14}C$, $^3H$.

• 대한지역사회영양학회지
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• 제28권6호
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• pp.466-479
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• 2023

Objectives: A mobile health intervention program was provided for employees with overweight and obesity for 12 weeks, and a process evaluation was completed at the end of the program. We investigated participant engagement based on app usage data, and whether engagement was associated with the degree of satisfaction with the program. Methods: The program involved the use of a dietary coaching app and a wearable device for monitoring physical activity and body composition. A total of 235 employees participated in the program. App usage data were collected from a mobile platform, and a questionnaire survey on process evaluation and needs assessment was conducted during the post-test. Results: The engagement level of the participants decreased over time. Participants in their 40s, high school graduates or lower education, and manufacturing workers showed higher engagement than other age groups, college graduates, and office workers, respectively. The overall satisfaction score was 3.6 out of 5. When participants were categorized into three groups according to their engagement level, the upper group was more satisfied than the lower group. A total of 71.5% of participants answered that they wanted to rejoin or recommend the program, and 71.9% answered that the program was helpful in improving their dietary habits. The most helpful components in the program were diet records and a 1:1 chat with the dietary coach from the dietary coaching app. The barriers to improving dietary habits included company dinners, special occasions, lack of time, and eating out. The workplace dietary management programs were recognized as necessary with a need score of 3.9 out of 5. Conclusions: Participants were generally satisfied with the mobile health intervention program, particularly highly engaged participants. Feedback from a dietary coach was an important factor in increasing satisfaction.

• Structural Engineering and Mechanics
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• 제68권3호
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• pp.335-344
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• 2018

The execution of an experiment is a complex affair. It includes the preparation of test specimens, the measurement process itself and also the evaluation of the experiment as such. Financial requirements can differ significantly. In contrast, the cost of numerical simulations can be negligible, but what is the credibility of a simulated experiment? Discussions frequently arise concerning the methodology used in simulations, and particularly over the geometric model used. Simplification, rounding or the complete omission of details are frequent reasons for differences that occur between simulation results and the results of executed experiments. However, the creation of a very complex geometry, perhaps all the way down to the resolution of the very structure of the material, can be complicated. The subject of the article is therefore a means of creating the material structure of concrete contained in a test specimen. Because a complex approach is taken right from the very start of the numerical simulation, maximum agreement with experimental results can be achieved. With regard to the automation of the process described, countless material structures can be generated and randomly produced samples simulated in this way. Subsequently, a certain degree of randomness can be observed in the results obtained, e.g., the shape of the failure - just as is the case with experiments. The first part of the article presents a description of a complex approach to the creation of a geometry representing real concrete test specimens. The second part presents a practical application in which the numerical simulation of the compressive testing of concrete is executed using the generated geometry.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6497-6500
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• 2012

Cervical cancer is the second most common cancer in females in the World with around 500,000 new cases occurring annually, but the first in the developing countries with a high mortality if not diagnosed early. Papanicolau (Pap) smear is a cheap, easy-to-apply and widely accepted test which has been long used to detect cervical cancer at very early stages. However, despite being available for nearly 60 years, the test can hardly be considered to have become successfully applied in many communities. We aimed in this study to present the results of a screening survey for cervical cancer which targeted a women population aged between 35 and 40 living in a semi-rural area in the province of Hatay, located in the eastern Mediterranean region of Turkey, with specific aims of increasing early diagnosis, education and raising population awareness about cancers. This community-based descriptive study covered 512 women between 35 and 40 years of age living at Armutlu with a mean age of $37.6{\pm}1.7$. Gynecologic examinations revealed cervical erosion in 8 (1.6%), vaginitis in 193 (37.7%) and normal findings in 311 (60.7%); pathological evaluation reports of the smears were negative in 290 (56.6%), inflammation in 218 (42.6%) and ASC-US in 4 (0.8%), according to the 2001 Bethesda classification. It can be concluded that Pap smear test - proven to be a very valuable test at the clinical level- should also be widely used at the community level to detect cervical cancer at very early stages to reduce both the mortality and morbidity among healthy people. The need for continuous community-based cervical cancer screening programs is strongly suggested.

• 한국농공학회지
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• 제40권5호
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• pp.68-79
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• 1998

In the years, the concern about high-strength concrete which is new material has been heightened as a result of active research and development. Recently, as the building structure has been being bigger, higher, longer and more specialized, the demand of material with high-strength concrete for building has been increasing. The demand of high -strength concrete is expected to increase with expansion of usage about the complex concrete structures such as bridge structure as well as nuclear plants, underground structures, hydraulic structures and arctic area sturctures. In this research, silica-fume was used as an admixture in order to get a high-strength concrete. Water/binder ration was limited no more than 18 percent and the amount of unit cement was increased. In this study, a number of trial in concrete mix was carried out to get optimal mix design, and the target slump with $10{\pm}2cm$ was set for in-situ construction. High-strength concrete with cylinder strength of 1,200kgf/$cm^2$ in the 28-days was produced and tested. The static test was carried out to measure the ultimate load, the initial load of flexural and diagonal cracking, crack patterns, fracture modes. The load versus strain and load versus deflection relations were obtained form the static test. The test results were compared with the shear strengths predicted by the equations of ACI code 318-89 and orther researchers. Based on the test results, shear strength equation of reinforced concrete beam using high strength concrete was proposed. Form an evaluation of the results of this experimental investigation, it was concluded that shear strength after diagonal tention cracking diminished with the increase in compressive strength for beams.

• 콘크리트학회논문집
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• 제17권6호
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• pp.879-884
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• 2005

응결시간은 터널 라이닝과 경사면의 보강 등의 품질에 영향을 미치는 매우 중요한 인자이다. 그러나 현재까지도 이를 개선하는데 이용될 급결제의 품질에 대한 기준은 잘 정립되어 있지 않은 상태이다. 본 연구에서는 급결제를 혼합한 시멘트의 응결시간 측정방법에 대한 평가가 Gillmore 및 Vicat needle 시험법들을 이용하여 수행되었다. 양 시험법에 있어서, 초결과 종결에 관계없이 동시첨가법이 후첨가법보다 우수하게 나타났다. Gillmore needle 시험법에서는 2종류의 측정법이 사용되었으며 동일한 급결제를 사용한 경우에도 시멘트의 종류에 따라 응결시간이 서로 달랐다. 따라서 급결제 제조사에서는 시멘트의 종류에 덜 민감한 급결제의 개발에 관심을 더 두어야 함을 알 수 있다. 한편, Vicat needle 시험법에서는 6종류의 측정법이 사용되었으며 급결제의 측정 방법에 대한 적절한 방법이 다음과 같이 제안되었다. (1) 사용되는 재료의 온도는 적절히 제어되어야 한다. (2) 급결제의 특성을 평가하기 위해서는 시멘트 무게 대비 $5\%$의 급결제를 사용해야 한다.

• 대한기계학회논문집A
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• 제40권9호
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• pp.791-799
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• 2016

최근 기계 시스템의 고속화가 진행됨에 따라 구조물 및 기계부품의 신뢰성 및 안전성 확보 측면에서, 충격하중하에서 구조용 재료의 동적변형거동에 대한 평가가 필요하다. 그러나 $10^4\;s^{-1}$를 넘는 고 변형률속도에서 실험적 기법을 사용한 구조용 재료의 변형거동의 파악은 용이하지 않은 실정이다. 본 연구에서는, 고 변형률속도역에서 금속재료의 동적변형거동을 조사하기 위해 Taylor 봉 충격시험을 실시하였다. 또한 고속영상촬영 시스템을 사용하여 Taylor 봉 충격시험 동안 변형거동을 관찰하였다. Taylor 봉 충격시, 경과시간에 따른 변형과정을 AUTODYN 상용 S/W를 사용한 수치해석을 수행하여 실험결과와 비교하여 고 변형률속도역에서 거동을 평가하였다.

• 대한인간공학회지
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• 제33권5호
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• pp.313-321
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• 2014

Objective: The purpose of this study is to develop products that prevent muscular skeletal disease of farm workers, which would bring improvement for an efficient harvesting work. Background: A pretest for product development and a survey research was carried out to inspect the problems of current harvesting work procedure. The product was developed and assessed based on ideas to supplement and improve these weak points. Method: A total of twenty men were recruited to evaluate the effects of harvest baskets on the upper-limb muscle activity, working hours. For the usability evaluation, electromyogram and working hours of previous working method (disuse of harvest basket, one-hand carriage of the basket) and new working method with the usage of newly-developed harvest basket was examined. The whole anterior deltoid, biceps brachii and erector spinae on both sides, which make a total of six muscle parts, were used for this experiment. The results were analyzed using ANOVA with muscle activity (%MVC) of each three forms of work and required work time from SPSS 18.0. Results: According to the test result, all muscles did not demonstrate any statistically significant difference, with an exception of the backbone erector (right). The muscle activity of backbone erector (right) in the work method that uses the harvest basket developed in this study was detected to be approximately 23% less than that of the previous working method. Moreover, compared to the previous working method, the required work time decreased to a statistically significant degree. Conclusion: As such, the decrease in the amount of waist muscle usage at harvesting work would enable the prevention of muscular skeletal disease and stabilization of lumbar spine. Application: Which in turn would increase the effectiveness and reduce personnel expense (labor costs) while enhancing productivity with a decreased working hours.

• Journal of Information Technology Applications and Management
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• 제20권2호
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• pp.57-68
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• 2013

Recently, cloud computing has been viewed as a technology of great influence. Despite the importance of personal cloud services, the majority of cloud computing studies has been focused on an enterprise level. Therefore, in this research, we list variables of personal cloud computing characteristics (accessibility, storage, trust, perceived ease of use, availability) from preceding research done on an enterprise level. So, through pilot testing, we analyze whether examined characteristic variables affect the intention to use personal cloud computing. Next, we investigate the relevancy between user characteristics, including gender, age, and occupation, and the usage rate of personal cloud computing. Lastly, we implement an analysis of variance in order to speculate whether there is any difference between the five characteristic variables in using personal cloud computing between cloud service enterprises. For empirical testing people with experience in personal cloud computing are surveyed. Frequency analysis, exploratory factor analysis, internal consistency analysis, T-test, ANOVA, and multiple regression analysis are implemented with 325 valid samples. The analysis results are as follows: First, among user characteristic variables, 'occupation' shows a significant relationship with cloud service usage, Second, between cloud service enterprises, all five characteristic variables of 'Naver N Drive' are thoroughly evaluated and 'Google Drive' receives a high evaluation in availability and accessibility. Third and finally, all of the selected characteristic variables affect the intention to use personal cloud computing. However, availability is identified to be the most important factor. This research will serve as a reference to enterprises for the practical implementation of personal cloud computing service.