• Title/Summary/Keyword: Urushiol

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A Study on Curing of Commercially Available Chines Urushiol (옻칠의 경화에 관한 연구)

  • Kim, Young-Baek;Park, Deok-Soo
    • The Journal of Natural Sciences
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    • v.8 no.2
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    • pp.21-26
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    • 1996
  • Commercially available Chines oriental lacquer was treated to get two fractions, hexane soluble fraction and hexane insoluble fraction. Hexane soluble fraction was subjected to thermal curing process. Films obtained from the lacquer under normal conditions and obtained from thermal curing were compared. The compounds in hexane soluble fraction were copolymerized with 1,6-diisocyanohexane, and toluendiisocyanate(TDI). Films obtained by thermal curing were highly brittle and hydrophobic while the films obtained under normal conditions were hydrophilic. Curing reaction did not occur when oxygen was not available.Some of the major component in the lacquer was isolated by HPLC and UV spectrum of each compound was recorded.

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A Clinical Case Report of Taeeumin Patient Diagnosed with Systemic Contact Dermatitis and Facial Flushing (전신성 접촉피부염과 안면홍조를 호소하는 태음인 환자 치험 1례)

  • Min-jung, Lee;Jiyeon, Lee;Min-woo, Hwang
    • Journal of Sasang Constitutional Medicine
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    • v.34 no.4
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    • pp.68-80
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    • 2022
  • Objectives This study is to report a significant improvement in a Taeeumin patient with systemic contact dermatitis after eating urushiol chicken by herbal medicine treatment. Methods The patient had complaints of erythema, swelling, pruritus, scaly skin, and facial flushing. We treated the patient with an herbal medicine 'Galgeunhaegi-tang' for three months. We evaluated the treatment outcome of systemic contact dermatitis using the Three Item Severity(TIS) score every visit and facial flushing by Image color summarizer at the first and last visit. Results After the treatment, the severity of the patient's skin complaints lessened from moderate to mild. The Image color summarizer showed a minor decrease in the normalized red color level and a significant increase in the brightness level and facial color percentage. Conclusions The patient diagnosed with systemic contact dermatitis, treated with Galgeunhaegi-tang for three months, showed a significant improvement in skin complaints with brighter and even facial color.

Antioxidant activities of Rhus verniciflua seed extract and quality characteristics of fermented milk containing Rhus verniciflua seed extract (옻씨 추출물의 항산화 활성과 옻씨 추출물을 첨가한 발효유의 품질특성)

  • Jin, Hee-Yeon;Choi, Yu-Jin;Moon, Hye-Jung;Jeong, Jae-Hee;Nam, Joong-Hyun;Lee, Sang-Cheon;Huh, Chang-Ki
    • Food Science and Preservation
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    • v.23 no.6
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    • pp.825-831
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    • 2016
  • This study was carried out to investigate the quality characteristics of fermented milk containing Rhus verniciflua seed (RVS) extracts (0.0%, 0.1%, 0.3% and 0.5%) and antioxidant activity of RVS extracts. The proximate composition of RVS was moisture (4.76%), crude ash (1.40%), crude fat (5.33%) and crude protein (11.10%). A total polyphenol content of 70% ethanol extract of RVS ($554{\pm}2.64mg/g$) was higher than that of RVS water extract ($145{\pm}3.47mg/g$). 70% ethanol extract ($1103{\pm}6.42mg/g$) of RVS showed higher content in the total flavonoids ($37{\pm}2.30mg/g$) and activities on DPPH free radical scavenging (73.23%) and ABTS free radical scavenging (83.47%) when compared with water extracted of RVS. The quality characteristics, such as pH, titratable acidity, and the number of lactic acid producing bacteria were not remarkably different between the fermented milk samples subjected to treatments with and without the addition of RVS extracts.

Anticancer and Antioxidant Activity of Allergen-Removed Extract in Rhus verniciflua Stokes

  • Kim, Myong-Jo;Choi, Won-Cheol;Barshinikov, A. M.;Kobayashi, A.
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.4
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    • pp.288-293
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    • 2002
  • Allergen-removed-extract was produced from Rush verniciflua by two phase methods. Phase one was high temperature treatment of Rush verniciflua tree to get allergen-removed-extract. Phase two was extraction of solution from phase one product using water or organic solvents. The solutions from above method show high antioxidant activity, anticancer activity, and improvement in lung function, but did not contain urushiol family compounds.

옻(Rhus Verniciflua) 추출물을 이용한 육가공 제품의 관능적 특성 및 물리적 특성 변화

  • 강민정;최선영;조현소;신정혜;성낙주
    • Proceedings of the Korean Journal of Food and Nutrition Conference
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    • 2004.07a
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    • pp.46-46
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    • 2004
  • 예로부터 옻은 항암성, 항산화성, 혈액순환기계 질환예방, 항균성 및 면역증강 작용 등이 있음이 알려져 왔다. 본 연구에서는 옻 중의 유독 성분으로 강한 알레르지를 유발하는 urushiol을 불활성화 시킨 기능성 옻 추출물을 첨가시킨 육가공품을 제조하였다. 소세지, 햄, 베이컨 및 족발 시료는 옻 추출물을 0.1% 첨가하여 사육한 돈육 및 일반 돈육에 옻 추출물을 2%, 4%및 8%첨가하여 제조한 시료에 대하여 4$^{\circ}C$에서 60일간 저장하면서 관능적 특성 및 물리적 특성을 조사하였다. (중략)

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Purification of Antioxidant substance from the stem bark of Rhus verniciflua

  • Kim, Jung-Bae
    • Proceedings of the Korean Journal of Food and Nutrition Conference
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    • 2001.12a
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    • pp.126-126
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    • 2001
  • The Rhus verniciflua contains alkly(en)-catechol type allergens with a saiurated or unsaturated alkly chain of 15 or 17 carbon atoms. It has been recognized as an extremely active allergen causing skin reactions similar In poison ivy. The allergic contact dermatitis induced by the urushiol is known to be mediated be T lymphocytes whicht specifically recognize the hepten urushiol. Therefore. direct use of this plant as a medicinal purpose might imply a considerable hazard in Korea. In this study, using the established method for the detoxification from the stem bark of Rhus verniciflua, an strong antioxidant substance was isolated and characterized DPPH (diphenypricryl hydrazyl) assay measures hydrogen atom-donating activity and hence provides a measure of free radical scavenging antioxidant activity. DPPH, a purple-colored stable free radical, is reduced to yellow-colored diphenylpicryl hydrazine by antioxidants to deducing agents. Antioxidative effects of the water extract from RV were measured by DPPH assay. Twenty microliters of the extract was added to 1ml of 100mM DPPH solution in ethanol The mixture was shaken and left to stand for 10min at room temperature. The crude water extracts was purified by using HPLC method with a DEAE (anionic type), CN, ODS column. The purified compound remained stable at pH 3.0-6,0, but unstable above pH 6.5. It was stable heat at 10$0^{\circ}C$ for 4 hours, but still had about 80% of residual activity after treatment at 10$0^{\circ}C$ for 5 hours. The elemental composition of the HR-EI mass spectrum at m/z 170.02 was estimated the empirical formula as $C_{7}$ $H_{6}$ $O_{5}$. $C_{10}$ $H_4$ $O_2$N$_1$, $C_{5}$ $H_4$ $O_4$N$_3$, $C_{8}$$H_2O$$_1$N$_4$. In antimicrobial test, no inhibition was observed against Gram-positive and negative bacteria. This compound was stronger than that of commercial antioxidant by DPPH test, such as BHT, BHC at the same concentration (20$\mu$g/ml).ml).

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Organic Material Analysis of a Lacquered Wooden Sheath of Long Sword with Ring Pommel Excavated in Imdang Ancient Tomb (경산 임당고분 출토 철제 고리자루칼 칠의 유기물 분석)

  • Park, Jongseo;Cho, Ha-nui;Lee, Jae-sung
    • Journal of Conservation Science
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    • v.34 no.5
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    • pp.369-377
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    • 2018
  • In order to examine the constituents and weathered state of a lacquer specimen, analysis of the organic materials was conducted using py/GC/MS(pyrolysis-gas chromatography-mass spectrometry). The samples were obtained from the lacquered wooden sheath of a long ring-pommel sword excavated in the Imdang No.1 ancient tomb constructed around the Proto-Three Kingdoms period. In direct py/GC/MS, the sample and the dried Asian lacquer showed similar chromatograms, while the characteristic compounds of Asian lacquer such as 1,2-dimethoxy-3-pentadecylbenzene were observed in THM(thermally assisted hydrolysis and methylation)-py/GC/MS. In addition, compounds like dimethyl nonanedioate, which presumably originated from drying oil, were also detected. Furthermore, the detection of oxidized catechols in considerable amount indicated that the degradation of lacquer is estimated to result from the oxidation of urushiol. Therefore, it is suggested that the lacquered wooden sheath was prepared using Asian lacquer and drying oil, and that the lacquer layer was considerably oxidized over the long burial time.

Reduction of Skin Allergy of Rhus verniciflua Sap Utilizing Radiation Technology (방사선 기술을 이용한 옻나무 수액의 피부 알러지 저감화 효과)

  • Jeong, Il Yun;Park, Yong Dae;Jin, Chang Hyun;Choi, Dae Seong;Byun, Myung-Woo;Ryu, Hyung Won;Kim, Dong Yong;Baek, Ji Yeong
    • Journal of Radiation Industry
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    • v.5 no.1
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    • pp.25-33
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    • 2011
  • Skin contact allergy (SCA) is not life-threatening, but a large number of people have been suffered from the reactions caused by various kinds of chemicals and products. Thus, in this study, radiation technology was employed to improve the traditional herb addition method on the SCA reduction of Rhus verniciflua sap (RVS). Rhus verniciflua has traditionally been used as an herbal medicine plant, but its urushiol derivatives are known as a major allergen for the SCA. The present study was commenced to assess the allergenicity of both gamma-irradiated and non-irradiated RVS by using guinea-pig maximization test (GPMT) in order to probe the mechanism of an SCA. In the acute dermal irritation assays, non-irradiated RVS caused erythema, but the irradiated RVS did not provoke any erythema on the abdominal skin of the guinea pigs. From the result of the GPMT, urushiols, the main chemical components of RVS, were identified as an extreme skin sensitizer, and the removal of urushiols by irradiation extremely reduced the erythema. These results suggest that radiation technology is a novel method to reduce SCA through the removal of urushiols of RVS.