• Childhood Kidney Diseases
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• 제1권1호
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• pp.67-72
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• 1997

목적 : 소아요로계 기형은 요로 감염의 주원인이며 발견시 비가역적인 신손상으로 만성 신부전과 고혈압의 원인이 되므로 조기 진단과 적절한 치료가 필수적이다. 이에 저자들은 요로계 전반의 선천성 기형의 발생양상을 알아보고자 본 연구를 시행하였다. 방법 : 1986년 1월부터 1996년 12월까지 전북대학병원 소아과에 입원한 환자중 방사선적인 검사상 요로계 기형이 발견된 124명을 대상으로 기형의 종류와 빈도, 동반기형, 임상증상, 요로감염의 동반유무, 치료방법 등에 관하여 임상기록을 토대로 조사하였다. 결과 : 1)연령분포는 1세 미만이 61명(49%)으로 가장 많았고 다음은 4-6세가 20명(16%)으로 많았다. 성별 빈도는 남아가 여아보다 2배정도 더 많았다. 2) 주증상은 발열이 가장 많았고 측복통, 산전진찰로 진단된 수신증, 복부종괴, 배뇨통, 빈뇨, 혈뇨등의 순이었다. 3) 요로계 기형은 방광 요관 역류가 가장 많았고 신우 요관 이행부 협착, 특발성 수신증, 중복 요로계, 거대요관 등의 순이었고 이중 85례에서 수신증이 동반되었다. 4) 단순기형은 109명(87%),복합기형은 15명(12%)으로 단순기형이 더 많았다. 5) 전체 124명중 68명(54.8%)에서 배양 검사에서 증명된 요로감염으로 104회 입원하였고 이때 동반된 기형으로는 방광요관 역류가 가장 많았으며 원인균은 E.coli(70%)가 가장 많았다. 6) 수술적 교정을 시행한 경우는 124명중 46명이었으며 이중 신우요관 이행부 헙착이 가장 많았다. 만성 신부전으로 진행한 경우는 7명이었고 후부 요도 판막에 의한 신부전 1명에서 신장이식을 시행하였다. 결론 : 소아에서 요로기형은 조기 진단과 적절한 치료를 시행하고 지속적인 추적관찰을 함으로써 심각한 합병증을 예방할수 있을 것으로 생각되며 향후 요로계 기형에 대한 더 많은 연구가 진행되어야 될 것으로 생각된다.

• 대한한방내과학회지
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• 제22권3호
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• pp.471-476
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• 2001

paralytic ileus and urinary tract infection(UTI) are common complications in stroke patient. A 78-year-old women was admitted because of right hemiparesis, motor aphasia due to 2nd cerebrovascular accident this patient had problem of paralytic ileus and UTI. without Western medical treatment, patient's symptom, sign and laborotory findings were improved through Korean medical treatment. so, we report it for the better treatment.

• Childhood Kidney Diseases
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• 제20권1호
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• pp.1-5
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• 2016

Since many years, continuous low dose antibiotic prophylaxis (CAP) has been used for children at a risk for recurrent urinary tract infection (UTI), especially those with vesicoureteral reflux (VUR). The incidence of recurrent UTI has been shown to be higher in children with VUR with bladder and bowel dysfunction (BBD) than in those with VUR without BBD. Therefore, CAP has been recommended for children with BBD and VUR because of the increased risk of UTI. However, the use of CAP has become highly controversial because of bacterial resistance developed due to antibiotic over-usage. The preventive effects of probiotics have been proved in various adult urogenital infections, and the antimicrobial activities of lactobacilli against uropathogens have been demonstrated in previous in vitro studies. However, a critical assessment of their efficacy in children with UTI is lacking. The importance of the use of urogenital probiotics is that it is a natural approach that replenishes the depleted normal flora to create a better environment to fight off uropathogens. Probiotics have a great potential, particularly today with the increasing threat of antibiotic-resistant microorganisms.

• 한국의료질향상학회지
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• 제23권2호
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• pp.81-94
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• 2017

Purpose:The purpose of this study was to evaluate the effects of periurethral cleaning with water or antiseptics in preventing catheter-associated urinary tract infections through systemic review Methods:The randomized clinical trials published between 2000 and 2016 were searched using domestic and international databases, and five randomized studies were selected for this study. The quality of study was assessed by assessment tool from the cochrane's Risk of Bias and meta-analysis was performed using the Cochrane Review Manager software Version 5.3 (RevMan) Results: The two groups of antiinfectants used in this study include povidone-iodine and chlorhexidine, water and chlorhexidine vs water and chlorhexidine. there was no significant difference in urinary tract infection rate between the two groups. Conclusion: Based on the findings, periurethral cleaning with water is safer and cost-efficient than using antiseptics. and it can make reduce a patient's discomfort.

• 대한의생명과학회지
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• 제7권3호
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• pp.117-125
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• 2001

This study was performed in order to evaluate the risk factors for nosocomial urinary tract infection and the frequencies of organisms isolated, and to provide the epidemiologic and basic data of hospital acquired urinary tract infection in intensive care unit. A prospective analysis was performed with 1,235 urine samples following urinary bladder catheterization in 569 patients, who had no evidence of UTI at the time of catheter insertion, admitted to intensive care unit in Pusan P hospital between June 1997 and May 1998. To identify risk factors for UTI, clinical characteristics of infected patients were analyzed. We analyzed these data by percentage, chi-square and odd ratio. Obtained results were as follows: A total of 569 patients (male 341 and female 228) were an average age of 50.8 years and catheterization of 8.04 days. Incidence of UTI was 16.1% (199/1,235) and The risk factors of UTI were duration of catheterization over 7 days, no use of systemic antibiotics, summer and female, and During the first 7 days these risk factors were no use of systemic antibiotics, summer, place of first catheter insertion (ICU) and type of intensive care unit (NSICU). A total of 220 the isolated strains were Gram negative rod 83 (37.7%), yeast like fungi 74 (33.6%) and Gram positive cocci 63 (28.6%). The common organisms isolated were Enterococcus faecalis 23 (10.5%), Serratia marcescens 19 (8.6%), Pseudomonu spp.17 (7.7%), E. ooh 16 (7.3%), Staphylococcus epidemidis 11 (5.0%) mdklebsiellapneumoniae 8 (3.6%). Therefore, in these results 199 of 569 (35%) patients in ICU with indwelling urinary catheter developed UTI. The risk factors for UTI are prolonged duration of catheterization, no use of systemic antibiotics, summer, and female.

• 성인간호학회지
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• 제18권2호
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• pp.314-322
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• 2006

Purpose: This study was designed to verify effects of perineal care with aroma essential oil on urinary tract infection(UTI) in patients with indwelling urinary catheter. Method: The research design was non equivalent control group pretest-post test design. The data were collected from March to August, 2005 at C university hospital in Seoul. The subjects were 43 patients who had a indwelling catheter in neurosurgery intensive care unit(NSICU). They were assigned to two groups, 21 subjects to the experimental group and 22 subjects to the control group. The experimental group received perineal care with 3% blending essential oil for 4 days. Results: In the experimental group, white blood cells and bacteria in urine were significantly lower than control group. Bacteria in urine culture was lower in the experimental group at post test. Conclusion: Perineal care with aroma essential oil could be an effective intervention to reduce the UTI of patients in NSICU.

• Childhood Kidney Diseases
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• 제1권1호
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• pp.60-66
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• 1997

목적 : 요로 결석은 소아에서는 비교적 드물다고 하나, 점점 증가하고 있으며, 유발요인이 있는 경우에는 보다 빨리 진단할 수 있다. 본 연구를 통하여 요로 결석 환아들의 주증상, 진단, 감염및 동반 질환 여부, 치료 등에 대하여 알아보고자 하였다. 방법 : 1986년 1월부터 1996년 6월까지 10년 5개월간 세브란스 병원에 내원한 15세 미만의 요로 결석환아 45명을 대상으로 후향적 고찰을 하였다. 결과 : 요로 결석 환아의 평균 연령은 6.5세, 남녀비는 5.4:1이었고, 가족력은 13.3%에서 나타났다. 주증상은 육안적 혈뇨가 가장 많았고, 요로 감염을 동반한 환아 46.1%,요로 기형 및 질환을 동반한 환아가 35.6%에서 나타났다. 진단 방법으로는 단순 요로 촬영, 경정맥 신우 조영술, 복부 초음파 등이 사용되었는데, 초음파만으로 진단받은 경우도 다수 있어 의의가 크다고 하겠다. 치료로는 체외 충격파 쇄석술, 경피적 신결석 적출술, 수액 요법, 이뇨제등이 사용되었다. 결론 : 소아 요로결석에 대해 관찰한 결과, 유의할 만한 질환으로 생각되며, 요로 폐색이 있는 환아에서는 시급한 치료가 요구된다. 특히 단순 방사선 촬영및 경정맥 신우 조영술에서 발견되지 않은 환아에서는 반드시 초음파를 하여 진단해야 할 것이다. 한편, 결석의 성분 분석이 이루어지지 않아 다소 아쉬운 점이 남는다.

• Biomolecules & Therapeutics
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• 제4권4호
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• pp.378-384
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• 1996

In vitro activities of LB20304a were compared with those of grepafloxacin (OPC-17116), Q-35, ciprofloxacin, and sparfloxacin against 380 clinical isolates collected from general hospitals in 1996. LB 20304a was the most active agent against gram-positive strains including staphylococci, streptococci and enterococci. LB20304a was also very active against gram-negative bacteria and its activity was comparable to that of ciprofloxacin but better than those of grepafloxacin, Q-35 and sparfloxacin. The therapeutic effect of LB20304a was superior to those of sparfloxacin and ciprofloxacin against systemic infection by methicillin-resistant Staphylococcus aureus K283 (MRSA) in neutropenic mice. Against urinary tract infection induced by Escherichia coli 851E in mice, LB20304a was more active than sparfloxacin and ciprofloxacin. However, LB 20304a was slightly less active than that of ciprofloxacin against urinary tract infection by Pseudomonas aeruginosa 1912E, but better than that of sparfloxacin.

• Childhood Kidney Diseases
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• 제21권2호
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• pp.101-106
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• 2017

Purpose: The aim of this study was to analyze the incidence and microbiological characteristics of urinary tract infection in infants aged younger three months and to compare with other infection with positive urine culture. Methods: We retrospectively reviewed the medical records of 425 infants with a tympanic temperature >$37.6^{\circ}C$, aged younger than three months, who were admitted to Cheil General Hospital in Seoul, Korea, from January 2013 to December 2016. Demographic and clinical features, laboratory findings, respiratory virus PCR and the pathogens of a urine culture were analyzed. Results: A total of 88 infants (63 males, 25 females) had urinary pathogens detected in the urine culture test. The incidence of UTI in febrile infants aged younger 3 months was 11%. The most common pathogen which causes UTI was E. coli as same as in previous studies. They were divided into a UTI group (n=48) and a non-UTI group (n=40). In comparison of both group, leukocytosis, C-reactive protein level, Absolute neutrophil count level, peak temperature is statistically significant. In both group, there were co-infections with viral pathogens in some cases, and the odd ratio of non-UTI group with viral infection was 3.28. Conclusion: The study determined the incidence and pathogen of UTI in febrile infants, aged younger three months. E. coli was responsible for the majority UTI. There were some viral co-infections in febrile infants with bacteriuria and incidence was higher in non-UTI group. WBC count, ANC count and CRP level were the differentiating factors of UTI from non-UTI group.

• 대한임상검사과학회지
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• 제53권3호
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• pp.277-283
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• 2021

Lactococcus속은 조건무산소성 그람양성알균으로 catalase 음성, 비운동성이며 10~40℃에서 배양된다. Lactococcus속은 16개의 종으로 구성되어 있으며, 그 중 Lactococcus garvieae와 Lactococcus lactis가 인간질병에 주로 관여하는 것으로 알려져 있다. 본 연구는 발열, 구토, 옆구리 통증으로 내원한 74세 여자의 소변 배양에서 Lactococcus garvieae가 배양된 사례를 최초 보고한다. 상기 환자는 의료기관에서 시행한 혈액검사, 미생물 배양검사, 컴퓨터단층촬영 등의 검사를 통해 급성 요로감염의 소견을 확인하였다. 신장내과 병동에 입원 후 수액처치 및 에리스로마이신 항생제 치료를 시행하였고 5일 후 환자는 퇴원하였다. 본 증례는 우리나라에서 처음으로 요로감염 환자의 소변에서 L. garvieae가 분리된 사례로서 향후 L. garvieae 감염 환자의 치료에 도움이 될 것이다.