• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1996.10a
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• pp.198-207
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• 1996

Electro sensitive traffic system can't consider passenger car unit, so, it causes start up delay time and passenger waiting time. In this paper, it antecedently creates optimal traffic cycle of passenger car unit at the bottom traffic intersection. But, sometimes it can make mistakes due to changes in car weight, car speed, and control of feed-back data. Moreover, to prevent spillback, it can adapt control even though upper traffic intersection has a different saturation rate, road length, road slope and road width.

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.776-781
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• 2001

To enhance thermal efficiency of thermal facility through recovery of low and medium temperature waste heat, 1MW organic Rankine cycle system was designed and developed. The exhaust gases of $175^{\circ}C$ at two 100MW power plants in pohang steel works were selected as the representative of low and medium temperature waste heat in industrial process for the heat source of the organic Rankine cycle system. HCFC-123, a kind of harmless refrigerant, was chosen as the working fluid for Rankine cycle. The organic Rankine cycle system with selected exhaust gases and working fluid was designed and constructed. From the operation, it was confirmed that the organic Rankine cycle system is available for low and medium temperature waste heat recovery in industrial process. The optimum operating manuals, such as heat-up of hot water, turbine start-up, and the process of electric power generation, were derived. However, electric power generated was not 1MW as designed but only 670kW. It is due to deficiency of pump capacity for supply of HCFC-123. So it is necessary to increase the pump capacity or to decrease the pressure loss in pipe for more improved HCFC-123 supply.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.11
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• pp.1610-1616
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• 2013

Recently, district heating and cooling (DHC) systems based on combined cycle generation (CCG) providers are increasing in Korea. Since characteristics of combined heat and power (CHP) generators and heat demands of providers, heat trading between DHC providers based on the economic viewpoint is required; the heat trading has been doing. In this paper, a mathematical model for optimal operation based on heat trading between DHC providers is proposed. Especially, start-up characteristic of CCG is included. The operation model is established by mixed integer linear programming (MILP).

• Proceedings of the KIEE Conference
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• 1991.07a
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• pp.162-165
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• 1991

Oxygen behaviors in CZ-silicon wafer, grown by the Lucky Advanced Materials Inc. that is a pioneer of silicon material industries in Korea, were investigated to simulate effects on the device performance of oxygen, neglecting the effect of other impurity content, defects and thermal history. Silicon wafers were annealed through simulated 16K SRAM thermal cycle. As initial oxygen concentration increased up to 16.7ppma the amount of oxygen precipitation increased up to 10.6ppma and the bulk microdefect density increased up to $10.3{\times}10^3/mm^2$, but the depth of the denuded zone decreased to $5.0{\mu}m$

• Parasites, Hosts and Diseases
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• v.57 no.2
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• pp.185-189
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• 2019

To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from the synchronized cell cultures. RNA-sequencing analysis of the 2 stages of Giardia cell cycle identified several cell cycle genes that were up-regulated at the G2-phase. Transcriptome analysis of cells in 2 distinct cell cycle stages of G. lamblia confirmed previously reported components of cell cycle (PcnA, cyclin B, and CDK) and identified additional cell cycle components (NEKs, Mad2, spindle pole protein, and CDC14A). This result indicates that the cell cycle machinery operates in this protozoan, one of the earliest diverging eukaryotic lineages.

• Mycobiology
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• v.51 no.5
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• pp.372-378
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• 2023

Lkh1, a LAMMER kinase homolog in the fission yeast Schizosaccharomyces pombe, acts as a negative regulator of filamentous growth and flocculation. It is also involved in the response to oxidative stress. The lkh1-deletion mutant displays slower cell growth, shorter cell size, and abnormal DNA content compared to the wild type. These phenotypes suggest that Lkh1 controls cell size and cell cycle progression. When we performed microarray analysis using the lkh1-deletion mutant, we found that only four of the up-regulated genes in the lkh1-deletion were associated with the cell cycle. Interestingly, all of these genes are regulated by the Mlu1 cell cycle box binding factor (MBF), which is a transcription complex responsible for regulating the expression of cell cycle genes during the G1/S phase. Transcription analyses of the MBF-dependent cell-cycle genes, including negative feedback regulators, confirmed the up-regulation of these genes by the deletion of lkh1. Pull-down assay confirmed the interaction between Lkh1 and Yox1, which is a negative feedback regulator of MBF. This result supports the involvement of LAMMER kinase in cell cycle regulation by modulating MBF activity. In vitro kinase assay and NetPhosK 2.0 analysis with the Yox1T40,41A mutant allele revealed that T40 and T41 residues are the phosphorylation sites mediated by Lkh1. These sites affect the G1/S cell cycle progression of fission yeast by modulating the activity of the MBF complex.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.10 no.4
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• pp.495-507
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• 1998

The transient characteristics of a 4.0㎾ inverter driven heat pump was investigated by theoretical and experimental studies. The heat pump used in this study consists of a high side scroll compressor and $\Phi$7 compact heat exchangers with two capillary tubes. A series of tests was peformed to examine the transient characteristics of heat pump in heating and cooling mode when the operating speed was varied from 30Hz to 102Hz. One of the major issues that has not been addressed so far is transient characteristics during speed modulation. A cycle simulation model has been developed to predict the cycle performance under frequency rise-up conditions, and the results of theoretical study were compared with the results of experimental study. The theoretical model was driven from mass conservation and energy conservation equations to predict the operation points of refrigerant cycle and the performances at various operating speeds. For transient conditions, the simulated results are in good agreement with the experimental results within 10%. The transient cycle migration of the liquid state refrigerant causes a significant dynamic change in system. Thus, the migration of refrigerant is the most important factor whenever An experimental analysis is performed or A simulation model is developed.

• Nutrition Research and Practice
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• v.2 no.4
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• pp.322-325
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• 2008

The aim of present study was to investigate the effects of kaempferol on cellular proliferation and cell cycle arrest and explore the mechanism for these effects in human breast carcinoma MDA-MB-453 cells. Cells were treated with kaempferol at various concentrations (ranging from 1 to $200\;{\mu}M$) for 24 and 48 hrs. Kaempferol significantly inhibited cancer cell growth in cells exposed to 50 and $10\;{\mu}M$ of kaempferol and incubated for 24 and 48 hrs, respectively. Exposure to kaempferol resulted in cell cycle arrest at the G2/M phase. Of the G2/M-phase related proteins, kaempferol down-regulated CDK1 and cyclin A and B in cells exposed to kaempferol. In addition, small DNA fragments at the sub-G0 phase were increased by up to 23.12 and 31.90% at 10 and $50\;{\mu}M$ incubated for 24 and 48 hrs, respectively. The kaempferol-induced apoptosis was associated with the up-regulation of p53. In addition, the phosphorylation of p53 at the Ser-15 residue was observed with kaempferol. Kaempferol inhibits cell proliferation by disrupting the cell cycle, which is strongly associated with the induction of arrest at G2/M phase and may induce apoptosis via p53 phosphorylation in human breast carcinoma MDA-MB-453 cells.

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.1
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• pp.127-132
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• 1993

Ten-week-old White Leghorn immature males and females were exposed to four lighting regimens: a constant light (12L : 12D); repeated up and slow down (13 min. up and 1 min. down per day for 13 consecutive days, and repeated on two-week cycle) lighting; repeated slow up and down (1 min. up per day for 13 consecutive days and 13 min. down, and repeated on two-week cycle) lighting; and step-up (14 min. up every second week) lighting. At 15 weeks of age, significantly larger testis and comb weights and significantly higher concentrations of plasma LH and testosterone were observed in the cockerels under the repeated slow up and down lighting regimen than those under the other lighting regimens. At 20 weeks of age, significantly larger oviduct weights and significantly higher concentrations of plasma estradiol were observed in the pullets under the repeated up and slow down, and the step-up lighting regimens than those under the other lighting regimens.

• Transactions of the Korean Society of Mechanical Engineers
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• v.6 no.2
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• pp.101-106
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• 1982

This study was undertaken to determine tensile properties and low-cycle fatigue behavior of 0.6%C high carbon steel used of structural purposes at temperatures up to 500.deg.C. In the low-cycle fatigue test the upper limit was decided by elongation(i.e. the total strain range), while the lower limit was defined by the load (i.e. zero load). The following results were obtained. Both, the ultimate tensile strength and low-cycle fatigue resistance attain the maximum values near 250.deg.C. Above this temperature the values decrease rapidly as the temperature increases. The low-cycle fatigue resistance decreases whenever there is an increase of the total strain range. Because the hardness of cycle fatigued specimen correlates cyclic hardening and cyclic softening, therefore the hardness of cycle fatigued specimen is smaller than that of the nonfatigued specimen at room temperature and 500.deg.C but much larger than the hardness of the nonfatigued specimen near 250.deg.C.