• 대한핵의학회:학술대회논문집
• /
• 대한핵의학회 2000년도 2nd Korea-China Congress of Nuclear Medicine and 39th Annual Spring Meeting if the Korea SOciety Nuclear Medicine
• /
• pp.68.2-68.2
• /
• 2000

• BMB Reports
• /
• 제38권1호
• /
• pp.77-81
• /
• 2005

The monocyte chemotactic protein-3 (MCP3), on chromosome 17q11.2-q12, is a secreted chemokine, which attracts macrophages during inflammation and metastasis. In an effort to discover additional polymorphism(s) in genes whose variant(s) have been implicated in asthma, we scrutinized the genetic polymorphisms in MCP3 to evaluate it as a potential candidate gene for asthma host genetic study. By direct DNA sequencing in twenty-four individuals, we identified four sequence variants within the 3 kb full genome including 1,000bp promoter region of MCP3; one in promoter region (-420T>C), three in intron (+136C>G, +563C>T, +984G>A) respectively. The frequencies of those four SNPs were 0.020 (-420T>C), 0.038 (+136C>G), 0.080 (+563C>T), 0.035 (+984G>A), respectively, in Korean population (n = 598). Haplotypes, their frequencies and linkage disequilibrium coefficients (|D'|) between SNP pairs were estimated. The associations with the risk of asthma, skin-test reactivity and total serum IgE levels were analyzed. Using statistical analyses for association of MCP3 polymorphisms with asthma development and asthma-related phenotypes, no significant signals were detected. In conclusion, we identified four genetic polymorphisms in the important MCP3 gene, but no significant associations of MCP3 variants with asthma phenotypes were detected. MCP3 variation/haplotype information identified in this study will provide valuable information for future association studies of other allergic diseases.

• 한국병원경영학회지
• /
• 제20권2호
• /
• pp.72-81
• /
• 2015

• 대한생식의학회:학술대회논문집
• /
• 대한불임학회 2006년도 제51차 추계학술대회
• /
• pp.122-123
• /
• 2006

• 임상간호연구
• /
• 제17권2호
• /
• pp.228-238
• /
• 2011

Purpose: The purpose of this study was to investigate parent expectation and satisfaction with respect to pediatric inpatient care and to identify the variables related to parent satisfaction. Methods: The study was conducted in pediatric wards of a tertiary children's hospital in Korea. The participants were 361 parents of children who were inpatients. Data were collected using a structured questionnaire (The Pediatric Family Satisfaction Questionnaire) at the time of discharge. Results: The highest parent expectation domain was medical service. The parents were most satisfied with nursing service and least satisfied with general hospital service and accommodation. The parents expressed lower satisfaction with hospital facilities, equipment, noise, cleanliness, and communication by health care professionals. Parents with younger children reported higher expectation from the complete hospital service and those who had a longer length of stay reported higher expectation from the nursing service. Conclusion: To improve the quality of hospital services, we need to understand parent expectation and improve and provide clear communication. In addition, the general hospital service and accommodation should not be overlooked for improvement.

• Journal of Korean Neurosurgical Society
• /
• 제66권5호
• /
• pp.605-608
• /
• 2023

• 대한의용생체공학회:학술대회논문집
• /
• 대한의용생체공학회 1995년도 추계학술대회
• /
• pp.157-158
• /
• 1995

• 대한임상약리학회:학술대회논문집
• /
• 대한임상약리학회 2003년도 제12차 추계학술대회
• /
• pp.20-21
• /
• 2003

• BMB Reports
• /
• 제54권5호
• /
• pp.284-284
• /
• 2021

• BMB Reports
• /
• 제56권7호
• /
• pp.416-416
• /
• 2023