• Title/Summary/Keyword: University Archives

Search Result 5,943, Processing Time 0.029 seconds

A New Triterpene Lactone from the Roots of Patrinia scabiosaefolia

  • Yang, Mi-Young;Choi, Young-Hae;Yeo, Ho-Sup;Kim, Jin-Woong
    • Archives of Pharmacal Research
    • /
    • v.24 no.5
    • /
    • pp.416-417
    • /
    • 2001
  • A new triterpene lactose named patrinolide A (7) has been isolated from the roots of Patrinia scabiosaefolia (Valerianaceae). Its structure was determined to be 11$\beta$,21$\beta$-dihydroxy-3-oxooleanan-28,13$\beta$-olide on the basis of spectral analysis, including 2D-NMR techniques.

  • PDF

Lignans of Rosa multiflora Roots

  • Yeo, Hosup;Chin, Young-Won;Park, Shin-Young;Kim, Jin-Woong
    • Archives of Pharmacal Research
    • /
    • v.27 no.3
    • /
    • pp.287-290
    • /
    • 2004
  • Five known lignans, (+)-pinoresinol (1), (+)-8-hydroxypinoresinol (2), (-)- dehydrodiconiferyl alcohol (3), (+)-trans-dehydrodiconiferyl alcohol (4), and (-)-olivil (5), were isolated from the roots of Rosa multiflora for the first time. Their structures were determined using spectroscopic data.

Synthesis and Cytotoxicity of New 3-Alkyl-1-(1-methyl-2-phenylethyl)ureas Related to Ceramide

  • Lim, Sejin;Ryu, Jae-Hark;Im, Chaeuk;Yim, Chul-Bu
    • Archives of Pharmacal Research
    • /
    • v.26 no.4
    • /
    • pp.270-274
    • /
    • 2003
  • A series of new 3-alkyl-1-(1-methyl-2-phenylethyl)ureas related to ceramide was synthesized and evaluated for their in vitro cytotoxic activity against five human tumor cell lines. The urea analogue (2b) of 813 showed comparable or slightly more potent cytotoxic activity as compared to B13, indicating that urea does appear to serve as a bioisostere of amide.

Flavonoids from Cirsium rhinoceros

  • Lee, Hwan-Bae;Kwak, Jong-Hwan;Zee, Ok-Pyo;Yoo, Seung-Jo
    • Archives of Pharmacal Research
    • /
    • v.17 no.4
    • /
    • pp.273-277
    • /
    • 1994
  • Six flavonoids were isolated from the aerial parts of Cirsium flavonoids were identified as apigenin, luteolin, $pectolinarigenin-7-O-{\betha}-D-glucopyranoside$, linarin, pectolinarin and $hispidulin-7-O-{\alpha}-L-rhamonopyranosyl-(1{\rightarrow}2)-{\betha}-D-glucopyranoside$ on the basis of chemical and spctral evidence.

  • PDF