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Furoquinoline Alkaloids from the Leaves of Melicope Confusa

  • Kang, Sam-Sik;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.9 no.1
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    • pp.11-13
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    • 1986
  • In addition to the previous reported furoquinoline alkaloids, skimmianine, kokusaginine and confusameline, a rate furoquinoline alkaloid, heliparifoline, mp 241-$3^{\circ}$ was isolated from the leaves of Melcope contusa and characterized by spectral data.

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Photocleavage of DNA by 4'-Bromoacetophenone Analogs

  • Jeon, Ra-Ok;Pual A.Wender
    • Archives of Pharmacal Research
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    • v.24 no.1
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    • pp.39-43
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    • 2001
  • 4'-Bromoacetophenone analogs, which are able to generate monophenyl radicals capable of hydrogen atom abstraction, were investigated as possible photoinducible DNA cleaving agents. The potential of 4'-Bromoacetophenone as a possible new DNA cleaver is explored. Pyrrolecarboxatmid conjugated 4'-Bromoacetophenone, in particular, DNA cleaving activity and sequence-selectivity on the contiguous AT base pair sites.

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Isolation of Triterpenoid and Phenylpropanoid from Codonopsis ussuriensis

  • Lee, Ihn-Rhan;Ko, Jeong-Hyun
    • Archives of Pharmacal Research
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    • v.15 no.4
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    • pp.289-291
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    • 1992
  • From the roots of Codonopsis ussuriensis (Rupr. et Maxim) Hemsley (Campanulaceae), taraxerol (mp 280-$282^\circ$), syringin (mp.$192^\circ$) and a new phenylpropanoid, ussurienoside I (syringin-3'-hydroxy-3'-methyl glutarate, mp. 102-$104^\circ$) were isolated.

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