• Archives of Plastic Surgery
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• v.49 no.5
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• pp.604-607
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• 2022

Nontuberculous mycobacterial hardware infections are extremely challenging to treat. Multidisciplinary care involving removal of infected hardware, thorough debridement, and durable soft tissue coverage in conjunction with antibiotic therapy is essential for successful management. This case report presents a patient with chronic mycobacterial spinal hardware infection that underwent successful treatment with aggressive serial debridements and reconstruction with a large pedicled superior gluteal artery perforator flap coverage.

• Archives of Pharmacal Research
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• v.15 no.4
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• pp.292-297
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• 1992

Coupling of naphthacylpyridinium bromide 2 [1-(2-naphthyl) ethanone-2-pyridinium bromide] with N-nitrosoacetarylamides afforded C-(2-naphthoyl)-N-arylmethanohydrazonoylpyridinium bromides 3A-C. Treatment of 3A-C with base afforded the corresponding tetrazines 6A-C. Cycloaddition of nitrilimines 5A-C to N-arylmaleimides, acrylonitrile, ethyl acrylate, acrylamide, fumaronitrile, $\alpha$-cyanocinnamonitriles, ethyl $\alpha$-cyano-p-nitrocinnamates and $\alpha$-cyano-p-nitrocinnamamide afforded the corresponding cycloadducts 7-14, respectively. The cycloadducts 11-14 undergo a facile thermal elimination of hydrogen cyanide to give the corresponding pyrazoles 18-21 respectively.

• Archives of Craniofacial Surgery
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• v.24 no.3
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• pp.129-132
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• 2023

Scalp defects necessitate diverse approaches for successful reconstruction, taking into account factors such as defect size, surrounding tissue, and recipient vessel quality. This case report presents a challenging scenario involving a temporal scalp defect where ipsilateral recipient vessels were unavailable. The defect was effectively reconstructed utilizing a transposition flap and a latissimus dorsi free flap, which was anastomosed to the contralateral recipient vessels. Our report underscores the successful reconstruction of a scalp defect in the absence of ipsilateral recipient vessels, emphasizing the importance of employing appropriate surgical interventions without necessitating vessel grafts.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.9-10
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• 2022

본 논문에서는 재난관련 스마트시티 플랫폼의 효율적 운영을 위한 기본단계로서 공개 데이터 사이트에서 다운로드받은 구급활동 일지 기록을 분석하여 환자들의 연령분포, 환자들의 상태, 월별발생추이, 출동 거리 등에 대한 기초자료를 추출한다. 공개에 동의한 환자들의 경우 사전에 자신의 의료 혹은 건강정보들을 기록해 놓음으로써 구급활동 절차를 많이 감소시킬 수 있으며 이 데이터 분석에 의해 추가될 구급 지구대의 위치와 구급차량의 수 등 다양한 의사결정을 수행할 수 있다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.4
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• pp.2476-2483
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• 2014

This study aims to review the characteristics of specialized classrooms for governmental secondary schools in the Japanese Colonial Era by analyzing architectural drawings collected by National Archives of Korea. The results of this study are summarized as follows 1) Under the influence of Japanese science promotion of that time, specialized classrooms for science were considered as one of essential facilities. Typically exclusive specialized classrooms were assigned to two major science subjects : physics-chemistry and biology. 2) To science specialized classrooms, ancillary rooms for preparation, experiment equipment and specimen were attached and science lecture room with stepped floor was planned additionally only for the lecture on theories and the demonstration of experiment. 3) Specialized classrooms for science were zoned independently of other facilities because of the special equipments and safety. 4) Art rooms were common to both boys' and girls' schools but concerning music rooms, girls' schools had special concerns, whereas boys' schools did not. 5) Specialized classrooms for homemaking subject of girls' school were as much important as those for science subjects of boys' school. 6) Some early-established Korean boys' schools had handicraft rooms which were the symbol of vocational education-oriented, unequal policy on Koreans. Though not general cases, specialized classrooms for geography-history were planned for Japanese boys' school. Restricted to governmental secondary schools but considering the uncommon state of specialized classrooms of that time, these characteristics show conditions of early time when special classrooms were introduced into Korea.

• Archives of Pharmacal Research
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• v.19 no.4
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• pp.292-296
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• 1996

By human intestinal bacteria, glycyrrhizin (18${\beta}$-glycyrrhetic acid ${beta}$-D-glucuronyl.${\alpha}$-D-glucuronic acid, GL) and baicalin (baicalein ${\beta}$-D-glucuronic acid) were metabolized to glycyrrhetinic acid and baicalin, respectively. However, .${\alpha}$-glucuronidase of Bacteroides JY-6 isolated from human intestinal bacteria hydrolyzed GL or 18.${\beta}$-glycyrrhetinic acid ..${\alpha}$-D-glucuronic acid to 18${\beta}$-glycyrrhetic acid but did not baicalin. However, E. coli ${\beta}$-glucironidase from human intestinal bacteria hydrolyzed baicalin to baicalein, but did not GL.${\beta}$-Glucuronidase of mammalian tissues hydrolyzed both GL and baicalin.

• Archives of Pharmacal Research
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• v.11 no.3
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• pp.181-184
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• 1988

The effect of clover saponin on the phase transition of liposomal lipid bilayers of dimyristoyl phosphatidylcholine was investigated with differential scanning calorimetry. The thermograms of the liposomal bilayers incorporated with the clover saponin were obtained, and the enthalpy changes and the sizes of cooperative unit of the transition were calculated. The results showed that incorporation of the clover saponin into the liposomal bilayers effectively reduced the transition temperature at which the transition from solid state to liquid-crystalline state occurs, and broadened the thermogram peaks. It also reduced the size of cooperative unit of the transition. These results indicate that the clover saponin might have significant effect on the fluidity of biological membranes.

• Archives of Pharmacal Research
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• v.12 no.2
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• pp.135-137
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• 1989

A convenient route is reported for the synthesis of certain series of 4H-thieno[2,3-b][1]benzothiopyran-4-ones, carrying various substituents at position 2 such as arylazomethines (7,8), thiazolidin-4-ones (9-13), ${\alpha},\;{\beta}-unsaturated$ ketones (16,17), 2-pyridones (19-23), tetrahydrothiophen-4-ones (24,28), and nitroalkenes (29,30), as potential schistosomicidal or antihistaminic agents.

• Archives of Pharmacal Research
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• v.12 no.2
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• pp.119-124
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• 1989

Cotton xanthate, which was obtained by treating cotton with carbon disulfide in alkaline solution, was treated with the solution of polyvalent metal ions to produce cotton xanthate-metal chelates. This chelation reaction was readily and simply achieved, and antimicrobial agents with suitable structures could subsequently be coupled to the chelate with ease at moderate pH values and in aqueous solution. Metal ions used in present work include Cu(II), Zn(II) and Fe(III). Tetracycline, streptomycin, neomycin and pyrithion were used as antimicrobial/antifungal agents. Antibacterial activities were measured employing ditch plate method against G(+) Staphylococcus aureus, Streptococus faecalis, and G(-) Escherichia coli, Enterobacter aerogenes, and the fungus, Aspergillus niger. All the cotton xanthate-metal-antimicrobial agent chelates exhibited activities whereas the cotton xanthate-metal chelates themselves were inactive. Considering the extensive washing procedures and results from control experiments, possibility of the involvement of physical adsorption for the binding of drugs could be excluded.

• Archives of Pharmacal Research
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• v.15 no.3
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• pp.256-262
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• 1992

For the evaluation of the role of substituents of ar-turmerone for its anticancer activity, ar-turmerone (1a) and its analogs like 2-methyl-6-(4'-methyphenyl)-2-octen-4-one (1b), 2-methyl-6-phenyl-2-hepten-4-one (1c), 2-methyl-6-phenyl-2-octen-4-one (1d) and 2 methyl-6-(trans-4'-methylcyclohexyl)-2-hepten-4-one (1e) were preparedd and their cytotoxic activities against $L_{1210}$ cell were determined. Omission of methyl group at para-position dose not variate the cytotoxicity of ar-turmerone. Elongation of alkyl group at 6-position decreases $ED_{50}$ value. Saturation of aromatic ring of ar-turmerone markedly decreases the cytotoxicity. Therefore the smaller size of alkyl group at 6-position and aromatic ring of ar-turmerone should be essential for exhibiting its anticancer activity.