• 제목/요약/키워드: University 2.0

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대학도서관 OPAC2.0 서비스 이용자 만족도와 중요도에 관한 연구 - A와 B대학도서관 도서검색결과를 중심으로 - (A Study on User Satisfaction and Importance of OPAC2.0 Services in University Libraries: Focusing on Book Search Result of A and B University Libraries)

  • 이혜영
    • 한국비블리아학회지
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    • 제28권1호
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    • pp.97-119
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    • 2017
  • 본 연구는 대학도서관에서의 도서검색결과 제공되는 OPAC2.0 서비스에 대한 만족도 중요도를 조사하였다. 대학도서관에서 도서검색결과 제공되는 OPAC2.0 서비스, 서비스의 만족도 중요도, 만족도와 중요도 차이 그리고 학년과 만족도 분석을 실시하였다. 조사 및 분석결과, 가장 많이 제공하고 있는 OPAC2.0 서비스는 '포털사이트 연계' 서비스이다. 전반적인 OPAC2.0 서비스 만족도는 평균 2.07로 '매우 불만족'으로 나타났으며 가장 중요하게 인식하고 있는 서비스는 '서비스 항목'이다. 만족도와 중요도 차이는 전반적으로 중요도에 비해 불만족스러운 결과를 보여 주고 있다. 학년과 전반적 만족도 차이는 나타나지 않았다. 이상의 분석결과를 토대로 향후 도서검색결과 OPAC2.0 서비스 개선을 위해서는 각 서비스에 대한 도서관 홍보 및 이용방법 소개, 다양한 서비스 제공 및 질적 개선, 도서관에서만 제공해 줄 수 있는 정보 제공을 통한 꾸준한 이용자 관리가 필요함을 제안하였다.

G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells

  • Cho, Eunah;Kwon, Yeo-Jung;Ye, Dong-Jin;Baek, Hyoung-Seok;Kwon, Tae-Uk;Choi, Hyung-Kyoon;Chun, Young-Jin
    • Biomolecules & Therapeutics
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    • 제27권6호
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    • pp.591-602
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    • 2019
  • Human breast cancer cell line, MDA-MB-231, is highly invasive and aggressive, compared to less invasive cell line, MCF-7. To explore the genes that might influence the malignancy of MDA-MB-231, DNA microarray analysis was performed. The results showed that G0/G1 switch 2 (G0S2) was one of the most highly expressed genes among the genes upregulated in MDA-MB-231. Although G0S2 acts as a direct inhibitor of adipose triglyceride lipase, action of G0S2 in cancer progression is not yet understood. To investigate whether G0S2 affects invasiveness of MDA-MB-231 cells, G0S2 expression was inhibited using siRNA, which led to decreased cell proliferation, migration, and invasion of MDA-MB-231 cells. Consequently, G0S2 inhibition inactivated integrin-regulated FAK-Src signaling, which promoted Hippo signaling and inactivated ERK1/2 signaling. In addition, G0S2 downregulation decreased ${\beta}$-catenin expression, while E-cadherin expression was increased. It was demonstrated for the first time that G0S2 mediates the Hippo pathway and induces epithelial to mesenchymal transition (EMT). Taken together, our results suggest that G0S2 is a major factor contributing to cell survival and metastasis of MDA-MB-231 cells.

웹 2.0 기반 교수 강의.연구지원 학술정보서비스 모델 개발 - 대학도서관을 대상으로 - (The Modeling of Scholarly Information Services in Order to Support Lecture and Research Activities for Faculties-Based Web 2.0 in Korea University Libraries)

  • 이응봉
    • 한국문헌정보학회지
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    • 제44권1호
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    • pp.157-180
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    • 2010
  • 본 연구에서는 우리나라 대학도서관 정보서비스의 질적인 향상 및 이용자 중심적인 서비스를 구현하기 위하여 우리나라와 미국의 주요 대학도서관들에서 시행하고 있는 교수의 교과목 강의 및 연구활동을 지원하는 관련 프로그램을 조사 비교 분석 평가하여 이를 벤치마킹하였다. 그리고 우리나라의 대학도서관 실정에 적합한 교수의 교과목 강의와 연구활동을 실질적으로 지원할 수 있는 웹 2.0(또는 라이브러리 2.0) 관련기술을 적용한 학술정보서비스 모델을 개발하는데 있어서 필요한 제반 고려사항을 제안하였다.

Monolithic zirconia crowns: effect of thickness reduction on fatigue behavior and failure load

  • Prott, Lea Sophia;Spitznagel, Frank Akito;Bonfante, Estevam Augusto;Malassa, Meike Anne;Gierthmuehlen, Petra Christine
    • The Journal of Advanced Prosthodontics
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    • 제13권5호
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    • pp.269-280
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    • 2021
  • PURPOSE. The objective of this study was to evaluate the effect of thickness reduction and fatigue on the failure load of monolithic zirconia crowns. MATERIALS AND METHODS. 140 CAD-CAM fabricated crowns (3Y-TZP, inCorisTZI, Dentsply-Sirona) with different ceramic thicknesses (2.0, 1.5, 1.0, 0.8, 0.5 mm, respectively, named G2, G1.5, G1, G0.8, and G0.5) were investigated. Dies of a mandibular first molar were made of composite resin. The zirconia crowns were luted with a resin composite cement (RelyX Unicem 2 Automix, 3M ESPE). Half of the specimens (n = 14 per group) were mouth-motion-fatigued (1.2 million cycles, 1.6 Hz, 200 N/ 5 - 55℃, groups named G2-F, G1.5-F, G1-F, G0.8-F, and G0.5-F). Single-load to failure was performed using a universal testing-machine. Fracture modes were analyzed. Data were statistically analyzed using a Weibull 2-parameter distribution (90% CI) to determine the characteristic strength and Weibull modulus differences among the groups. RESULTS. Three crowns (21%) of G0.8 and five crowns (36%) of G0.5 showed cracks after fatigue. Characteristic strength was the highest for G2, followed by G1.5. Intermediate values were observed for G1 and G1-F, followed by significantly lower values for G0.8, G0.8-F, and G0.5, and the lowest for G0.5-F. Weibull modulus was the lowest for G0.8, intermediate for G0.8-F and G0.5, and significantly higher for the remaining groups. Fatigue only affected G0.5-F. CONCLUSION. Reduced crown thickness lead to reduced characteristic strength, even under failure loads that exceed physiological chewing forces. Fatigue significantly reduced the failure load of 0.5 mm monolithic 3Y-TZP crowns.

감성돔(Acanthopagrus schlegelii) 및 참돔(Pagrus major) 치어에 대한 이산화염소(ClO2)의 급성 독성 (Acute Toxicity of Chlorine Dioxide (ClO2) to Juvenile Black Seabream Acanthopagrus schlegelii and Red Seabream Pagrus major)

  • 이옥;서준혁;서형원;장다희;이재만;최태건;박정환
    • 한국수산과학회지
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    • 제53권3호
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    • pp.451-455
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    • 2020
  • This study evaluated acute toxicity of chlorine dioxide (ClO2 ) to juveniles of black seabream Acanthopagrus schlegelii (19.4±2.3 g, 10.7±0.4 cm) and red seabream Pagrus major (74.9±8.2 g, 15.9±1.0 cm). Thirty juveniles for each species were exposed to target ClO2 concentrations of 0, 0.05, 0.1, 0.125, 0.15, 0.2, 0.3, 0.4, and 0.5 mg/L in triplicate for eight days. Half lethal concentrations for 96 hours were found at 0.14 and 0.24 mg ClO2/L for black seabream and red seabream, respectively. Red seabream larger than black seabream in body weight appears to be more resistance to chlorine dioxide. However, regardless of species or size, specific loading rates of chlorine dioxide to total fish weight (daily feeding amount of ClO2/total fish weight) were similar, showing 1.3 and 1.1 g ClO2/kg fish·day-1 for black seabream and red seabream.

Ni0.5Zn0.4Cu0.1Fe2O4 Complex Ferrite Nanoparticles Synthesized by Chemical Coprecipitation Predicted by Thermodynamic Modeling

  • Kang, Bo-Sun;Park, Joo-Seok;Ahn, Jong-Pil;Kim, Kwang-Hyun;Tae, Ki-Sik;Lee, Hyun-Ju;Kim, Do-Kyung
    • 한국세라믹학회지
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    • 제50권3호
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    • pp.231-237
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    • 2013
  • Thermodynamic modeling of the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ complex ferrite system has been adopted as a rational approach to establish routes to better synthesis conditions for pure phase $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ complex ferrite. Quantitative analysis of the different reaction equilibria involved in the precipitation of $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ from aqueous solutions has been used to determine the optimum synthesis conditions. The spinel ferrites, such as magnetite and substitutes for magnetite, with the general formula $MFe_2O_4$, where M= $Fe^{2+}$, $Co^{2+}$, and $Ni^{2+}$ are prepared by coprecipitation of $Fe^{3+}$ and $M^{2+}$ ions with a stoichiometry of $M^{2+}/Fe^{3+}$= 0.5. The average particle size of the as synthesized $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$, measured by transmission electron microscopy (TEM), is 14.2 nm, with a standard deviation of 3.5 nm the size when calculated using X-ray diffraction (XRD) is 16 nm. When $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ ferrite is annealed at elevated temperature, larger grains are formed by the necking and mass transport between the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ ferrite nanoparticles. Thus, the grain sizes of the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ gradually increase as heat treatment temperature increases. Based on the results of Thermogravimetric Analysis (TGA) and Differential Scanning Calorimeter (DSC) analysis, it is found that the hydroxyl groups on the surface of the as synthesized ferrite nanoparticles finally decompose to $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ crystal with heat treatment. The results of XRD and TEM confirmed the nanoscale dimensions and spinel structure of the samples.

Electrochemical Characteristics of LiMnO2 for Lithium Secondary Battery

  • Jin Bo;Jun Dae-Kyoo;Gu Hal-Bon
    • Transactions on Electrical and Electronic Materials
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    • 제7권2호
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    • pp.76-80
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    • 2006
  • Well-defined orthorhombic $LiMnO_2\;and\;LiCo_{0.1}Mn_{0.9}O_2$ were synthesized by a solid-state reaction and quenching process. X-ray diffraction (XRD) results revealed that the as-synthesized powders showed an orthorhombic phase of a space group with Pmnm. The $Li/LiMnO_2\;and\;Li/LiCo_{0.1}Mn_{0.9}O_2$ cells were constituted and cycled galvanostatically in the voltage range of 2.0-4.3 V vs. $Li/Li^+$ at a current density of $0.5\;mA\;cm^{-2}$ at room temperature and $50^{\circ}C$, respectively. The results demonstrated that the highest specific capacity of $Li/LiMnO_2$ cells at room temperature and $50^{\circ}C$ was 95 and $155\;mAh\;g^{-1}$, respectively. As for $Li/LiCo_{0.1}Mn_{0.9}O_2$ cells, the highest specific capacity at room temperature and $50^{\circ}C$ was 160 and $250\;mAh\;g^{-l}$, respectively. It could be seen that the performance of $Li/LiCo_{0.1}Mn_{0.9}O_2$ cells was better than that of $Li/LiMnO_2$ cells.

수소저장용 금속수소화물$(Mm(La_{0.6-0.8})Ni_{4.0}Co_{0.6}Mn_{0.2}Al_{0.2})$의 전열촉진 (Heat transfer enhancement of metal hydride $(Mm(La_{0.6-0.8})Ni_{4.0}Co_{0.6}Mn_{0.2}Al_{0.2})$ for hydrogen storage)

  • 배상철
    • 신재생에너지
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    • 제2권2호
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    • pp.75-80
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    • 2006
  • The effective thermal conductivities of $Mm(La_{0.6-0.8})Ni_{4.0}Co_{0.6}Mn_{0.2}Al_{0.2}$ [TL-492] with hydrogen and helium have been examined. Experiment results show that pressure has great influence on effective thermal conductivity in low pressure range [below 0.5 MPa]. And that influence decreases rapidly with increase of gas pressure. The reason is at low pressure, the mean free path of gas becomes greater than effective thickness of gas film which is important to the heat transfer mechanism in this research. And, carbon fibers have been used to try to enhance the poor thermal conductivity of TL-492. Three types of carbon fibers and three mass fractions have been examined and compared. Naturally, the highest effective thermal conductivity has been reached with carbon fiber which has highest thermal conductivity, and highest mass fraction. This method has acquired 4.33 times higher thermal conductivity than pure metal hydrides with quite low quantity of additives, only 0.99 wt% of carbon fiber. This is a good result comparing to other method which can reach higher effective thermal conductivity but needs much higher mass fraction of additives too.

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리튬 2차 전지용 LiCo1-XMgxO2(x=0.03)의 결정구조, 전기전도도 및 전기화학적 특성 (Crystal Structures, Electrical Conductivities and Electrochemical Properties of LiCo1-XMgxO2(x=0.03) for Secondary Lithium Ion Batteries)

  • 김호진;정우창;정연욱;이준형;김정주
    • 한국세라믹학회지
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    • 제42권9호
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    • pp.602-606
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    • 2005
  • [ $LiCoO_{2}$ ] is the most common cathode electrode materials in Lithium-ion batteries. $LiCo_{0.97}Mg_{0.03}O_2$ was synthesized by the solid-state reaction method. We investigated crystal structures, electrical conductivities and electrochemical properties. The crystal structure of $LiCo_{0.97}Mg_{0.03}O_2$ was analyzed by X-ray powder diffraction and Rietveld refinement. The material showed a single phase of a layered structure with the space group R-3m. The lattice parameter(a, c) of $LiCo_{0.97}Mg_{0.03}O_2$ was larger than that of $LiCoO_2$. The electrical conductivity of sintered samples was measured by the Van der Pauw method. The electrical conductivities of $LiCoO_2$ and $LiCo_{0.97}Mg_{0.03}O_2$ were $2.11{\times}10^{-4}\;S/cm$ and $2.41{\times}10^{-1}\;S/cm$ at room temperature, respectively. On the basis of the Hall effect analysis, the increase in electrical conductivities of $LiCo_{0.97}Mg_{0.03}O_2$ is believed due to the increased carrier concentrations, while the carrier mobility was almost invariant. The electrochemical performance was investigated by coin cell test. $LiCo_{0.97}Mg_{0.03}O_2$ showed improved cycling performance as compared with $LiCoO_2$.

컴팩트 개질기용 수성가스전이 반응에서 Cu-Ce0.8Zr0.2O2 촉매에 Cu 담지량이 미치는 영향 (The Effect of Cu Loading on the Performance of Cu-Ce0.8Zr0.2O2 Catalysts for Single Stage Water Gas Shift Reaction)

  • 김학민;전경원;나현석;장원준;정대운
    • 한국수소및신에너지학회논문집
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    • 제28권4호
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    • pp.345-351
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    • 2017
  • Single stage water-gas shift reaction has been carried out at a gas hourly space velocity of $150,494h^{-1}$ over $Cu-Ce_{0.8}Zr_{0.2}O_2$ catalysts prepared by a co-precipitation method. Cu loading was optimized to obtain highly active co-precipitated $Cu-Ce_{0.8}Zr_{0.2}O_2$ catalysts for single stage water-gas shift reaction. 80 wt.% $Cu-Ce_{0.8}Zr_{0.2}O_2$ exhibited the excellent catalytic performance as well as 100% $CO_2$ selectivity (CO conversion = 27% at $240^{\circ}C$ for 50 h). The high activity and stability of 80 wt.% $Cu-Ce_{0.8}Zr_{0.2}O_2$ are correlated to low activation energy and large amount of surface Cu atoms.