• 대한핵의학회:학술대회논문집
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• 2000.05a
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• pp.72.1-72.1
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• 2000

• Korean Business Review
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• v.10
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• pp.155-190
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• 1997

• International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
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• v.26 no.1
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• pp.99-100
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• 1998

• BMB Reports
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• v.40 no.2
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• pp.196-204
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• 2007

Our previous study has shown that sodium selenite can cause apoptosis in acute promyelocytic leukemia-derived NB4 cells in a caspase-dependent manner, but the detailed mechanism is unknown. Here we demonstrate a requirement for extracellular signal-regulated protein kinase (ERK) in mediating sodium selenite -induced apoptosis in NB4 cell. Though no apparent elevation of ERK activity was observed during the apoptosis in NB4 cells caused by 20 μM sodium selenite treatment, PD98059 and U0126, specific chemical inhibitors of the MEK/ERK signaling pathway, were shown to strongly prevent the apoptosis process, while ERK activator TPA enhanced the process. It is also known that p38 MAPK inhibitor SB203580 and JNK inhibitor SP600125 had slight effects on apoptosis. Further study indicated that ERK exerted its proapoptotic effect only at the early stage of apoptosis and played an antiapoptotic role at the later stages. Taken together, our findings suggest that ERK plays an active role in mediating sodium seleniteinduced apoptosis in NB4 cells .

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4421-4427
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• 2015

Objectives: To investigate the prognosis significance of preoperative serum alpha-fetoprotein (AFP) and the correlation with clinicopathological factors of hepatocellular carcinoma (HCC) patients who underwent hepatectomy. Materials and Methods: Clinicopathological data of retrospective analysis were collected for 251 HCC patients undergoing hepatectomy in this study. According to preoperative AFP level, patients were categorized into AFP-negative (0-20ng/mL) and AFP-positive (>20 ng/mL) groups for Kaplan-Meier analysis and Cox proportional hazard regression modeling. Results: The results demonstrated that increased AFP was associated with longer prothrombin time (PTs), liver capsule invasion, low grade differentiation, and late Barcelona Clinic Liver Center (BCLC) stage. Moreover, the female patients had a greater prevalence of increased preoperative AFP than male patients [284.8 (3.975-3167.5) vs (3.653-140.65); Z-2.895, p=0.004]. The 1-, 3-, and 5-year recurrence-free survival (RFS) rates were 78.1, 57.5, and 40.6 % in the AFP-negative group and 61.8, 37.7, and 31.4 %, respectively, in the AFP-positive group (log-rank test 8.312, p=0.004). The 1-, 3-, and 5-year overall survival (OS) rates were 94.4, 83.8, and 62.3% in the AFP-negative group and 87.2, 60.0, and 36.7%, respectively, in the AFP-positive group. The difference was statistically significant (log-rank test, 16.884, p=0.000). Cox proportional-hazards model identified preoperative AFP to be an independent prognostic predictor of overall survival. Conclusions: Preoperative serum AFP is an independent predictor of prognosis among HCC patients following surgical resection. Female patients have a higher preoperative AFP than their male counterparts.

• Journal of Labour Economics
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• v.30 no.3
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• pp.43-75
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• 2007

This study reviews the trend of job separation rates for three years from 2002 to 2005 and investigates the various elements which influence this trend, especially the role of the labor unions, by using Korean Labor Panel data. In the basic statistics, the job retention rate of union members were higher by an average of 28.3% points compared to non-union members, but in the results of controlling the observed variables of individual influences in changing jobs, it was estimated that unions increase the job retention rate by 11% to 13% points. To investigate the effect of unions on the job stability of workers in detail, the non-linear decomposition method developed by Fairlie (2003) was used in the analysis. In examining the difference of job separation rates between union members and non-union members through observed variables of workers in explainable parts and unexplainable parts by using the non-linear decomposition technique, the contribution of the explainable part was estimated to be 67% to 74% and the unexplainable part accounted for the rest which was 26% to 33%. This suggests that not only does the union contribute to the job stability of its members, but the propensity to change jobs for a worker who is a union member is on average lower than that of a worker who is not a union member or who works at an establishment that does not have a union. The results of the empirical analysis show that the job stability effect of labor unions is limited within the boundary of a maximum 7% to 9% points. The reason for the effect of labor unions on job stability being so low is due to various reasons such as collective bargaining structure by company, intensified business competition after the financial crisis, and labor market segmentation.

• Journal of information and communication convergence engineering
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• v.5 no.2
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• pp.140-143
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• 2007

Fingerprint Recognition System is made up of Off-line treatment and On-line treatment; the one is registering all the information of there trieving features which are retrieved in the digitalized fingerprint getting out of the analog fingerprint through the fingerprint acquisition device and the other is the treatment making the decision whether the users are approved to be accessed to the system or not with matching them with the fingerprint features which are retrieved and database from the input fingerprint when the users are approaching the system to use. In matching between On-line and Off-line treatment, the most important thing is which features we are going to use as the standard. Therefore, we have been using "Delta" and "Core" as this standard until now, but there might have been some deficits not to exist in every person when we set them up as the standards. In order to handle the users who do not have those features, we are still using the matching method which enables us to make up of the spanning tree or the triangulation with the relations of the spanned feature. However, there are some overheads of the time on these methods and it is not sure whether they make the correct matching or not. In this paper, introduces a new data structure, called Union and Division, representing binary fingerprint image. Minutiae detecting procedure using Union and Division takes, on the average, 32% of the consuming time taken by a minutiae detecting procedure without using Union and Division.

• 한국정보교육학회:학술대회논문집
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• 2010.08a
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• pp.37-49
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• 2010

In the present study, we analyzed plans and outcomes on the information society and Information technology in education in the European Union to provide implications for national policy in Korea. For this, we examined a political program of the European Union, called the eEurope initiative, as well as programs of the eLearning Initiative. Particularly, we analyzed European Union e-learning policy and discussed its implications for national convergence in Korea. In addition, we offer four suggestions for Korean policy on the information technology in education after analyzing outcomes, issues, and directions related to the European Union's policy.

• Journal of Distribution Science
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• v.18 no.5
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• pp.61-70
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• 2020

Purpose: The aim of this paper is to investigate whether labor unions are the main determinants of advertising expenditures and whether market competition has an impact on the relation between labor unions and advertising expenditures, focusing on distribution firms. Research design, data, and methodology: Using 914 observations of KOSPI market from 2001 to 2009 in distribution firms, this paper examines whether labor union is related to advertising expenditures, focusing on distribution firms. For this, this paper employs not only OLS regressions method but also 2SLS regressions method in which Female_Ratio(percentage of female employees) is used as instrumental. Results: This paper finds that in the distribution firms, labor union, as a major stakeholder of the company is, in terms of statistic, negatively associated with advertising expenditures. Also, market competition, in this paper, doesn't have real impact on the relation between labor unions and advertising expenditures. Conclusions: This paper presents the influence of labor unions, as a major factor in determining advertising expenditures. An executive who understands that as the amount of advertising expenditure increases, the total pie of wages to be attributed to the members of labor union will decrease.

• Journal of Labour Economics
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• v.28 no.1
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• pp.105-133
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• 2005

This paper attempts to verify that the economic gap between the workers in (large) firms with unions and those in (small and medium size) firms with no unions has recently been widened rapidly. A comparison of the wages of the workers belonging to the business establishments with and without trade union shows that the union premium has increased very sharply since 1997, after a relatively long periods with little changes. Also found is that union sector has witnessed a sharper decline in the share of the new entrants among workers as well as a faster increase of the average tenure of workers. These all indicate that the trade unions have forced a market equilibrium to move farther away from the competitive equilibrium in recent years.