• 한국방사선학회논문지
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• 제13권2호
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• pp.201-207
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• 2019

본 연구는 갑상샘 초음파에서 K-TIRADS 분류와 K-TIRADS 분류에 따른 Different risk group의 조합을 이용한 방법이 양성과 악성 결절의 감별진단에 유용한지를 평가하였다. 갑상샘 초음파를 시행한 210명을 대상으로 하였으며, 세침흡인세포검사 결과를 바탕으로 후향적인 분석을 하였다. 갑상샘 결절의 양성과 악성에 따른 K-TIRADS와 Different risk group의 점수체계의 차이 분석은 카이제곱 검정을 하였다. ROC 곡선 분석을 통해 악성 결절의 예측을 위한 K-TIRADS 점수와 Different risk group의 최적 cut off 값을 결정하였다. 양성과 악성 결절 군의 분류에 따른 K-TIRADS와 Different risk group의 차이검증 결과에서 각각 통계적으로 유의한 차이를 보였다(p=.001). ROC 곡선 분석에서 양성과 악성 결절의 예측을 위한 K-TIRADS에 따른 점수분류에서는 AUC 0.786, Cut-off value> 2를 나타내었으며, Different risk group에서는 AUC 0.640, Cut-off value> 2로 결정되었다(p=.001). 갑상샘 초음파에서 결절을 발견했을 때 양성과 악성 갑상샘 결절을 감별하는 데 도움을 주는 K-TIRADS에 따른 분류체계가 Different risk group에 따른 분류체계보다 갑상샘 결절의 감별진단에 도움을 줄 것으로 생각하며 K-TIRADS에 따른 분류체계를 적용하면, 불필요한 세포 검사를 줄일 수 있고, 악성 결절의 조기발견에 도움이 될 것으로 생각된다.

• 한국음향학회지
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• 제21권8호
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• pp.744-756
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• 2002

현재 복부용 초음파 진단장치에 가장 일반적으로 사용되고 있는 3.5 ㎒의 굴곡형 선형배열 (curved linear array) 탐촉자가 인체 중에 만드는 과도음장을 체계적으로 해석함으로써, 음장의 측면에서 보다 우수한 초음파 영상이 기대되는 탐촉자의 설계 파라메터를 도출하고자 시도하였다. 음장해석에 있어서는 방사파형을 일정하게 가정한 상태에서 탐촉자 요소의 크기, 곡률 반경, 개구내 압전소자에 대한 구동신호의 진폭 가중치 적용 등의 파라메터를 음장 형성의 지배적인 요소로서 고려하였다. 시뮬레이션의 결과, 탐촉자의 곡률 반경 및 개구높이를 줄이고 해밍 (Hamming) 창 형태의 진폭 가중치 적용을 실시함으로써 기존의 전형적인 탐촉자보다 부엽 (side lobe)의 영향이 적은 우수한 초음파 빔을 형성하는 새로운 탐촉자의 설계 파라메터가 얻어졌다.

• 동의생리병리학회지
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• 제32권4호
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• pp.217-225
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• 2018

This study was to investigate the relationship between ultrasonographic examination and pattern identification classification on cinical studies in chinese medicine. We searched clinical studies related correlation between ultrasonographic examination and pattern identification classification in chinese medicine, that published from 2013 to 2016 in China National Knowledge Infrastructure (CNKI) databases by keywords, 'ultrasound(超?)', 'chinese medicine(中?)', 'syndrome differentiation (辨?)'. Seventeen studies were found. There were 7 studies of gynecological diseases including polycystic ovary syndrome and uterine myoma, 5 studies of fatty liver, 3 studies of arthritis, and 1 studie of thyroid nodule and lymphadenopathy respectively. As a result, ii is thought that there was a certain degree of correlation between the change of the ultrasonographic image and the pathological types according to traditional chinese medicine (TCM) syndrome differentiation and ultrasonographic examination could be used as secondary means for the TCM syndrome differentiation classification. In conclusion, by using ultrasonograph device in a medicinal way of TCM and traditional korean medicine (TKM), it is thought that more detailed and accurate diagnosis and treatment are possible and the evidence for reasonableness of syndrome differentiation in TCM and TKM its validity can be secured.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.231-239
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• 2006

Functional medicine is a system which utilizes certain investigative and treatment methods that are primarily oriented toward the recognition of functional disorder. Functional disorders take place on an energetic plane. This plane is not capturable using our regular investigatory techniques, such as X -ray. ultrasound, computer tomography and laboratory analyses. The 7-zone-diagnostic system(VEGA-DFM 722 and ABR-2000, etc) is a diagnostic device Which applies pulse signals to predetermined bodily locations. Applying alternating positive and negative stress to tissues with positive and negative pulses first manifests itself as negative and positive wave forms. The skin has many functions as an organ. It is the organism's interlace with the outsider world. Hence, the manner in which the skin reacts to external stimuli reflects the current state of the organism(as meridian systems). This system make a diagnosis of functional disorder or some typical organic diseases include stress of the mind or the body, and the energetic situation, reserves. We are known a disorder or disease throw the result chart. This result chart contain disorder flow wave forms and some valuable diagnostic hints (letters ; S, OM, RA, etc). In spite of this 7-zone-diagnostic system that is applied plentifully in the clinical application, there is not a statistics which is suitable. Therefor we must carry out many various research in the future.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권4호
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• pp.286-290
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• 2016

Inspissated bile syndrome (IBS) is a rare condition in which thick intraluminal bile, including bile plugs, sludge, or stones, blocks the extrahepatic bile ducts in an infant. A 5-week-old female infant was admitted for evaluation of jaundice and acholic stool. Diagnostic tests, including ultrasound sonography, magnetic resonance cholangiopancreatography, and a hepatobiliary scan, were not conclusive. Although the diagnosis was unclear, the clinical and laboratory findings improved gradually on administration of urodeoxycholic acid and lipid emulsion containing omega-3 polyunsaturated fatty acids (PUFAs) for 3 weeks. However, a liver biopsy was suggestive of biliary atresia. This finding forced us to perform intraoperative cholangiography, which revealed a patent common bile duct with impacted thick bile. We performed normal saline irrigation and the symptom was improved, the final diagnosis was IBS. Thus, we herein report that IBS can be treated with omega-3 PUFAs as an alternative to surgical intervention.

• Childhood Kidney Diseases
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• 제19권1호
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• pp.8-13
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• 2015

Antenatal hydronephrosis (ANH) is one of the most common abnormal findings detected on prenatal ultrasound (US), and it has been reported in 1-5% of all pregnancies. The likelihood of significant postnatal pathologic abnormality in the urinary tract correlates with the degree of anterior-posterior diameter (APD) according to the gestational age. Detection of urologic anomalies prenatally permits fetal interventions that avoid complications in rare cases of bladder outlet obstruction with oligohydramnios even though their final benefits still remain controversial. There is no clear consensus on the extent and mode of postnatal imaging after a diagnosis of ANH. US is the mainstay of the postnatal evaluation and helps guide further testing with voiding cystourethrography (VCUG) and diuretic renography. Although most algorithms continue to recommend generous VCUG for identification of lower urinary tract anomalies, VCUG may be safely reserved for high grade ANH cases or any grade of ANH with dilated distal ureter without increasing the risk of urinary tract infection (UTI). There are conflicting studies about efficacy of postnatal prophylactic antibiotics. It still seems reasonable to consider use of a prophylactic antibiotic to prevent infant UTIs in high-risk populations, such as females and uncircumcised males with high grades of hydronephrosis, hydroureteronephrosis, or vesicouretral reflux.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2871-2877
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• 2015

Background: Urothelial carcinoma (UC) is a malignant neoplasm that most commonly occurs in the urinary bladder. The primary aim of this study was to evaluate the clinicopathologic features, recurrence and progression in patients with bladder urothelial cancer. Materials and Methods: The medical records of patients diagnosed with UC in the state pathology laboratory between January 2006 and July 2014 were retrospectively included. Carcinomas were categorized according to age, gender, histologic grade, tumor configuration, pathologic staging, recurrence status, and progression. Results: A total of 125 (113 men, 12 women) patients were examined. The mean age was 65.9 years and the male-to-female urothelial cancer incidence ratio was 9.4:1. Low-grade UCs were observed in 85 (68%) and high-grade in 40 (32%). A papillary tumor pattern was observed in 67.2% of the UCs. Cases were classified with the following pathological grades: 34 (27.2%) cases of pTa, 70 (56%) of pT1, and 21 (16.8%) of pT2. Recurrence occurred in 27 (21.6%) patients. Ten progressed to a higher stage (pT1 to pT2), and three cases to higher grade (low to high). We also analyzed the results separately for 70 (56%) patients 65 years of age and older. Conclusions: With early detection and diagnosis of precursor lesions in older patients, by methods such as standard urologic evaluation, urinary cytology, ultrasound scanning and contrast urography, and cystoscopy, in addition to coordinated efforts between pathologists and urologists, early diagnosis may reduce the morbidity and mortality of patients with urothelial carcinoma.

• 대한핵의학회지
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• 제36권1호
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• pp.34-38
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• 2002

Positron emission tomography(PET) is an imaging method that employs radionuclide and tomography techniques. Since 1995, we applied PET not only to the diagnosis of breast cancer but also to the detection of abnormalities in the augmented breast and to the detection of metastasis. Until 2001, we evaluated 242 breast cases by PET at PET center of Seoul National University Hospital. Our group has reported serially at the international journals. In the first report, PET showed high sensitivity for detecting breast cancer, both the primary and axillary node metastasis. A total of 27 patients underwent breast operations based on PET results at Seoul National University Hospital from 1995 to 1996. The diagnostic accuracy of PET were 97% for the primary tumor mass and 96% for axillary lymph node metastasis. In case of the breast augmented, PET also showed excellent diagnostic results for primary breast cancer and axillary lymph node metastasis where mammography and ultrasound could not diagnose properly. PET also had outstanding results in the detection of recurrent or metastatic breast cancer(sensitivity 94%, specificity 80%, accuracy 89%). In addition, our study gave some evidence that PET could be applied further to evaluate the growth rate of tumors by measuring SUV, and finally to prognosticated the disease. PET could also be applied to evaluate the response after chemotherapy to measure its metabolic rate and size. In conclsion, PET is a highly sensitive, accurate diagnostic tool for breast cancer of primary lesion in various conditions including metastasis.

• Archives of Plastic Surgery
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• 제35권6호
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• pp.729-734
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• 2008

Purpose: The evaluation and management of a completely transected tendon of the hand is relatively clear. In most cases, the integrity is assessed by physical examination(eg, broken normal cascade, motion loss) but occasionally, It happens in troubles. because of pain, limited patient cooperation(eg, child, unconscious patient), and other associated injuries(eg, fractures, foreign bodies). Methods: From september 2006 to August 2007, 28 patients were evaluated with real time ultrasonography preoperatively and postoperatively. Twenty eight patients with injured tendon were evaluated using an HDI 5000 Sono CT(Philips Medical Systems, Bothell, WA) machine with a high resolution, 7.5MHz hockey stick linear probe. Dynamic evaluation was performed in real time. Results: Surgery was performed after the ultrasonographic evaluation. Sonographic diagnosis and intraoperative findings were correlated. Ultrasonographic findings show tendon discontinuity, gaps, and fluid collection. Conclusion: We conclude that ultrasonography is helpful in evaluating and managing acute tendon injury. Especially, in cases of completely lacerated tendon, ultrasonography can identify the location of the proximal tendon stump and partial lacerated tendon, ultrasonographic diagnostic tool can decrease misdiagnosis.

• Advances in pediatric surgery
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• 제6권1호
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• pp.19-26
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• 2000

This paper reports our 9-year experience treating 34 infants with biliary atresia utilizing a new non-invasive diagnostic method, ultrasonographic "triangular cord"(TC) sign. The TC sign is present when there is visualization of a triangular or a band-like echogenicity just cranial to the portal vein. The ultrasonographic TC sign appears to be a simple, non-invasive, time-saving and useful tool in the diagnosis of biliary atresia. Sensitivity is 84 %. Active bile excretion was restored in 90 % of the patients who were treated between 31-60days, 78 % of those between 61-90 days, and 33 % of those being 91days or older. The incidence of postoperative cholangitis was 36 %. Construction of an antireflux valve in the Roux-en-Y loop did not affect the incidence of postoperative cholangitis(p=0.18). Among 34 infants with biliary atresia, 23(68 %) are alive for 2-102 months after operation, and 12 are alive for more than 5 years. Five-year estimate survival by Kaplan-Meier method was 66 %.