• 제목/요약/키워드: U-factor

검색결과 1,476건 처리시간 0.025초

3-(4′-hydroxyl-3′, 5′-dimethoxyphenyl) Propionic Acid Suppresses NO Production and Elevates GSH Levels in Murine Macrophages

  • Song, Young-Sun;Choi, Chun-Yeon;Suh, Hongsuk;Song, Yeong-Ok
    • Preventive Nutrition and Food Science
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    • 제9권3호
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    • pp.270-275
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    • 2004
  • Previous studies have shown that kimchi and kimchi-derived 3-(4'-hydroxyl-3', 5'-dimethoxyphenyl) propionic acid have anti-oxidative and hypolipidemic effects in rats and rabbits. This study was designed to investigate whether chemically synthesized 3-(4'-hydroxyl-3', 5' -dimethoxyphenyl) propionic acid (HDMPPA) may ameliorate oxidative stress through the regulation of nuclear factor KB (NFkB) activation in lipopolysaccharide (LPS)-stimulated RAW 264.7 murine macrophage cells. Treatment of RAW 264.7 cells with 400 uM of HDMPPA significantly reduced LPS-stimulated nitric oxide (NO) production. Treatments with HDMPPA at 100 uM to 400 uM concentrations significantly elevated glutathione (GSH) level. However, cell viability and thiobarbituric acid-reactive substances (TBARS) concentrations were not affected by the concentrations of HDMPPA used. The specific DNA binding activities of NFKB, a transcription factor which is sensitive to oxidative stress, were not down-regulated by HDMPPA treatments. These results suggest that HDMPPA may have weak anti-oxidative activity against LPS challenge by scavenging NO and stimulating GSH production.

자궁근종과 자궁평활근 세포분열에 있어 Interferon-${\alpha}$ 및 basic Fibroblast Growth Factor (bFGF)의 효과 (The Effect of Interferon-${\alpha}$ and bFGF on the Proliferation of Cultured Leiomyoma and Myometrial Cells)

  • 이병석;박정식;김진영;배상욱;박기현;조동제;이국;김재욱;송찬호
    • Clinical and Experimental Reproductive Medicine
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    • 제24권3호
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    • pp.355-359
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    • 1997
  • Leiomyomas, which are the commonest pelvic tumors in women, are originated from myometrial cells. Although the exact initial pathophysiologic event of the leiomyoma is not known, recent evidences suggested that the effects of sex steroid hormones in the process of tumor growth are mediated by local production of growth factors including epidermal growth factor (EGF), insulin-like growth factor-I (IGF-I) and insulin-like growth factor-II (IGF-II). If we look at the effects of other cytokines, it was suggested that basic fibroblast growth factor (bFGF) may stimulate the proliferation of myometrial and leiomyomas cells. And it was reported that interferon-${\alpha}$ inhibit the action of bFGF. Therefore, we examined the effect of bFGF and interferon-${\alpha}$ on the proliferation of leiomyoma and myometrial cells. bFGF stimulated the myometrial and leiomyoma cells significantly at the concentration of 1ng/ml (p<0.05) and 5ng/ml (p<0.05). However, Interferon-${\alpha}$ inhibited the cell proliferation of myometrial and leiomyoma cells significantly at the concentration of 100U/ml (p<0.05) and 1000U/ml (p<0.05). And the stimulated effects of bFGF with the various concentration on the myometrial and leiomyoma cells ware inhibited by interferon-${\alpha}$ with 100U/ml. Therefore, we concluded that bFGF may stimulate the myometrial and leiomyoma cell proliferation and interferon-${\alpha}$ may inhibit the myometrial and leiomyoma cell proliferation through blocking the effect of basic fibroblast growth factor.

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쇼핑가치, 사용용이성, 유용성이 모바일 구매의도에 미치는 영향 (The Effects of Shopping Value, Ease of Use, and Usefulness on Mobile Purchase Intention)

  • 채진미
    • 감성과학
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    • 제20권2호
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    • pp.73-86
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    • 2017
  • 본 연구에서는 모바일 환경에서 패션제품을 구매할 때 소비자의 구매의도에 영향을 미치는 영향 변수로 쇼핑가치와 새로운 기술을 수용하는데 영향을 주는 신념 변수로 알려진 사용용이성과 유용성을 채택하여 경로모형을 구성하여 검정하였고, 구매경험에 따른 집단 별(중구매/경구매 집단)로 경로모형을 비교분석하였다. 온라인 설문 전문업체를 통해 스마트 폰을 통해 패션제품을 구매한 경험이 있는 20-30 대 성인을 대상으로 설문지 분석을 시행하였고, 총 411부의 유효한 데이터를 SPSS 21과 AMOS 19 프로그램을 이용하여 분석하였다. 쇼핑가치는 감성적인 차원의 쾌락적 쇼핑가치와 실용적인 차원의 실용적 쇼핑가치로 분류되었고 구성변수의 신뢰성이 확인되었다. 경로모형의 적합성은 적합한 것으로 입증되었으며, 최근 1년 동안 스마트폰을 통해 패션제품을 구매한 횟수에 따라 중구매 집단과 경구매 집단으로 분류하여 경로모형을 비교분석한 결과는 다음과 같다. 두 집단 모두 공통적으로 쾌락적 가치보다는 실용적 가치가 모바일 구매의도에 미치는 직접적인 영향력이 유의한 것으로 나타났고, 사용용이성은 직접적으로 구매의도에 영향을 미치기보다는 유용성을 거쳐 구매의도에 영향을 미치는 것으로 나타났다. 구체적으로 중구매 집단의 경우, 쾌락적 쇼핑가치가 구매의도에 주는 영향과 사용용이성이 구매의도에 주는 영향을 제외하고는 모든 경로가 유의한 것으로 나타났다. 경구매 집단에서는 쾌락적 쇼핑가치가 사용용이성에 주는 영향, 실용적 쇼핑가치가 유용성에 주는 영향, 쾌락적 쇼핑가치가 구매의도에 주는 영향, 사용용이성이 구매의도에 주는 영향의 경로가 유의하지 않은 것으로 밝혀졌다. 본 분석 결과는 다양한 유통채널을 사용하여 제품을 구매하는 현대 소비자들을 모바일 구매로 유도하기 위한 차별화된 모바일 마케팅 전략을 수립하는데 근거가 될 것이다.

SM45C와 SCM4의 마찰용접 및 피로특성에 관한 연구 (A Study on Friction Welding of SM45C to SCM4 Steel Bars and the Fatigue Properties)

  • 오세규;김부안;김선진;남상훈
    • 한국해양공학회지
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    • 제2권2호
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    • pp.112-121
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    • 1988
  • A study on friction welding of carbon steel bar (SM45C) to chrome molybedenum steel bar(SCM4) is examined experimentally through tensile test, hardness test, microstructure test and fatigue test. so, this paper deals with optimizing the welding concitions and analyzing various mechanical properties about friction welds of SM45C to SCM4 steel bars. The results obtained are summarized as follows; 1) For friction welded joints of SM45C to SCM4 steel bars, the total upset(U)increases linearly with an increase of heating time ($t_{1}$) till 6s. 2) The determined optimum welding conditions are heating time ($t_{1}$)2s, upsetting time($t_{2}$), 3s, heating pressure($p_{1}$), 4kgf/$mm^{2}$(39.2MPa), upsetting pressure($p_{2}$, 8kgf/mm$^{2}$(78.4MPa) and rotating speed(N), 2, 000rpm when the total upset(U) is 3.4mm, resulting in a computed relationship between the joint tensile strength .sigma.$_{t}$ (kgf/mm$^{2}$and the total upset U(mm); .sigma.$_{t}$ =$0.21U^{3}$ - $3.38U^{2}$ +17.03U + 66.00 3) As the elongation is increased more and more, the fracture position becomes away from weld interface and the fractures are similar to those of SM45C. Fracture is taken place on SM45C side. 4) The weld interface of two dissimilar materials is mixed strongly, and the heat affected zone is about 2.0mm at SM45C while about 2.7 mm at SCM4 side. Therefore, the welded zone and heat affected zone are very narrow, comparing with those of the joints welded by the other welding methods. 5) The fatigue strengths at N=10$^{6}$ cycles of SM45C, SCM4 and friction welded joints are 23kgf/$mm^{2}$, 33kgf/$mm^{2}$(220.5 MPa), and 22.5kgf/$mm^{2}$(220.5MPa) respectively, and fracture at friction welded joint takes place at the side of SM45C. 6) The hardness of the friction weld interface is 3 times higher than that of base metal. 7) Fatigue strength of friction welded joint is higher than that of base metal. 8) Notch sensitivity factor of friction welded joint is lower than that of base metal.

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3차원 유한요소해석에 의한 얕은 기초의 지지력 특성 (Bearing Capacity Characteristics of Shallow Foundation by Three Dimension FEM)

  • 박춘식;김종환
    • 한국지반공학회논문집
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    • 제35권3호
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    • pp.17-24
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    • 2019
  • 본 연구는 지반 위 얕은 기초의 지지력에 대한 특성을 파악하기 위하여 지반 조건, 기초 크기, 기초 형상 등의 다양한 조건에 대하여 3차원 유한요소해석을 수행하여 기존의 지지력 이론과 비교 검토하였다. 유한요소해석 결과 극한지지력은 기초크기에 따라 지지력이 거듭제곱이나 로그 식으로 차츰 수렴하였고, 지반강도가 증가할수록 지지력 증가가 커지지 않는 직선적인 변화를 보였다. 기존 지지력 이론과 비교한 결과 순수모래는 지지력 비($q_{FEA}/q_{theory}$)가 Terzaghi식의 결과와 가장 유사하였다. 순수점토는 약 0.4~0.6, 일반토사는 0.3~1.3 정도로 산정되었고, 지반강도가 증가할수록 지지력 비가 감소하면서 1.0 이하로 나타났다. 기초 크기에 따른 지지력을 1.0m 기초의 지지력으로 정규화시킨 지지력 비($q_u/q_{u(1.0)}$)는 순수모래에서 ${\phi}=25^{\circ}$, $30^{\circ}$, $35^{\circ}$일 때 이론식의 35%, 15%, 5% 정도로 산정되었고, 순수점토는 크기 효과가 없었으며, 일반토사는 지반강도가 작은 경우에 순수모래의 이론식에 대해 약 10% 이하로 나타났다. 지반강도 증가에 따른 지지력 비는 내부마찰각의 영향이 큰 것으로 나타났다. 기초형상별 지지력 비에 따른 형상계수는 기초형상에 따라 다르게 나타났고, 원형기초는 1.5, 정사각형 기초는 1.3, 직사각형 기초와 연속 기초는 1.1~1.0의 형상계수를 나타내었다.

YBCO 고온 초전도체의 Rietveld 해석 연구 (Rietveld Analysis of YBCO superconductor)

  • 채기병;이상운;소대화
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1995년도 춘계학술대회 논문집
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    • pp.182-186
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    • 1995
  • In this pacer, it is examined and confirmed that the R factor which is compensated after analyzing the characteristics of superconductor resulted from this experimented theory with the computer simulation, is refined to R$\sub$WP/=8.83[%], R$\sub$P/=6.47[%], R$\sub$I/=10.08[%], RF=7.19[%], R/eub E/=3.76(%), and on the basis of these experimental data, the significant parameter such as the scale factor(s) and the zero point shift(Z) and FWHM value(U,V,W) are optimized as follows; S =72.0827E-3, Z=0.2146, U=4.2761E-2, V=1.7983E-2, and W=2.6768E-2

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THE INVESTIGATION OF BURNUP CHARACTERISTICS USING THE SERPENT MONTE CARLO CODE FOR A SODIUM COOLED FAST REACTOR

  • Korkmaz, Mehmet E.;Agar, Osman
    • Nuclear Engineering and Technology
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    • 제46권3호
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    • pp.407-412
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    • 2014
  • In this research, we investigated the burnup characteristics and the conversion of fertile $^{232}Th$ into fissile $^{233}U$ in the core of a Sodium-Cooled Fast Reactor (SFR). The SFR fuel assemblies were designed for burning $^{232}Th$ fuel (fuel pin 1) and $^{233}U$ fuel (fuel pin 2) and include mixed minor actinide compositions. Monte Carlo simulations were performed using Serpent Code1.1.19 to compare with CRAM (Chebyshev Rational Approximation Method) and TTA (Transmutation Trajectory Analysis) method in the burnup calculation mode. The total heating power generated in the system was assumed to be 2000 MWth. During the reactor operation period of 600 days, the effective multiplication factor (keff) was between 0.964 and 0.954 and peaking factor is 1.88867.

천이경계층에서의 간헐도 측정에 관한 실험적 연구 (Experimental Study on Measuring the Intermittency in the Transitional Boundary Layer)

  • 임효재;안재용;백성구;정명균
    • 설비공학논문집
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    • 제15권1호
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    • pp.9-18
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    • 2003
  • An experimental study was performed to investigate the turbulence intermittency measuring methods across the boundary layer in the transition region. A single type hot-wire probe was used to measure instantaneous streamwise velocities in laminar, transitional and turbulent boundary layer To estimate wall shear stresses on the flat plate, near wall mean velocities are applied to the principle of CPM. Distribution of intermittency factor is obtained by dual-slope method and compared to the results of four methods,$\'{u},\;\{U}$, TERA and M-TERA method. In these methods, M-TERA shows a good agreement in the near wall region. However, the result of M-TERA method shows that intermittency factor is underestimated in the outer part and outside of the boundary layer and the dimensional constant of M-TERA method should be changed appropriately depending on measuring point.

2017 - T 3 알미늄 合金 의 勞龜裂進展 과 龜裂닫힘現象 (Fatigue crack growth and crack closure in 2017-T3 Aluminum alloy)

  • 송지호;김일현;신용승
    • 대한기계학회논문집
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    • 제4권2호
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    • pp.47-53
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    • 1980
  • Kikukawa-Compliance method using a conventional clip-on gauge was employed to investigate fatigue crack growth and crack closure in 2017-T3 aluminum alloy. The crack growth rate plot against stress intensity range .DELTA.K on a log-log diagram exhibits a bilinear form with a transition at the growth rate of 10$\^$-4/ mm/cycle. The bilinear form appears still in the plot of growth rate versus effective stress intensity range .DELTA.K$\_$eff/. Fatigue crack growth rate could be well represented by .DELTA.K$\_$eff. The experimental results indicate that the effective stress intensity range ratio U depends on the maximum stress intensity factor K$\_$max/, but the stress ratio R does not affect U. The crack opening stress intensity factor K$\_$op/ tends to increase with increasing K$\_$max/ and decrease with increasing .DELTA.K.

한국과 미국 대학생의 의류 제품 만족에 관한 비교 문화 연구 - 청바지에 대한 친숙도와 추구 이미지를 중심으로 - (A Cross-Cultural Study on the Consumer Satisfaction of Clothing between Korea and the United States - Focusing on Familiarity and Pursuited Image of Jeans)

  • 박수경
    • 복식문화연구
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    • 제15권1호
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    • pp.169-178
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    • 2007
  • The purpose of this study was to compare consumers' post acquisition behavior by analyzing the influence of familiarity of jeans, and pursued image. The data was collected by using survey, three stages of pre-tests, and main survey conducted in the U.S and Korea. A total of 520 participants from each country(260 males and 260 females) was used. The results of this study is as follows. Familiarity of jeans and pursued image of jeans wear were compared between Korean and American students. As a result, there was difference between the countries on familiarity that the U.S showed higher familiarity, frequence of wearing and owned quantity. Pursued image was consisted of unique factor and activity factor and Korean students showed higher score on pursuing individualistic image. The results of this study would provide marketing strategy for fashion marketers of global jean brands.

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