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A Study on the Effect of Changchuldointanggami-bang(Cāngzhútáoréntāngjiāwèi-fāng) in Rheumatoid Arthritis (창출도인탕가미방(蒼朮桃仁湯加味方)이 류마토이드 관절염에 미치는 실험적 연구)

  • Park, Eun-Sook;Yoon, Il-Ji
    • Journal of Korean Medicine Rehabilitation
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    • 제19권4호
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    • pp.1-18
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    • 2009
  • Objectives : This study was carried out to understand the immune responses of the Changchuldointanggami-bang(after referred to CDIT) on antioxidants, THP-1 cell and rheumatoid arthritis in Collagen-induced Arthritis(CIA) mice. Methods : The antioxidative effect of CDIT on DPPH free radical and SOD-like activity was measured. CDIT was administered to THP-1 cell, cytokine and mRNA associated with inflammation were measured. CDIT was orally administered to mice with arthritis by collagen II and then cytokine, PBMC in the serum were measured. Results : 1. The scavenging activity of CDIT on DPPH free radical was dose-dependent. 2. The effect of CDIT on SOD-like activity was dose-dependent. 3. The production of $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ was decreased significantly in THP-1 cell. 4. The expression of $IL-1{\beta}$ mRNA, IL-6 mRNA, $TNF-{\alpha}$ mRNA were decreased significantly in THP-1 cell. 5. $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ were decreased significantly in the serum of CIA mice. 6. CD3+, CD4+, CD8+ were increased significantly, but CD3+/CD69+, CD3+/CD49b+, B220+/CD23+ were decreased significantly in PBMC of CIA mice. Conclusions : Taking all these observations into account, CDIT is considered to be effective in rheumatoid arthritis. Therefore we have to survey continuously in looking for the effective substance and mechanism in the future.

Factors Affecting the Postoperative Pain and Length of Hospital Stay of Liver Transplantation Donors (간이식 공여자의 수술 후 통증 특성 및 재원기간에 대한 영향 요인)

  • Jung, Je Hyun;Bang, Kyung-Sook
    • The Journal of Korean Academic Society of Nursing Education
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    • 제24권4호
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    • pp.433-442
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    • 2018
  • Purpose: This study was performed to investigate the factors affecting postoperative pain and length of hospital stay of liver transplantation donors. Methods: This is a retrospective study using the Electronic Medical Records (EMR) of 91 patients operated on at a tertiary hospital in Seoul, Korea in 2016. The collected data were analyzed using descriptive statistics, t-test, Mann-Whitney U test and Kruskal-Wallis test, Spearman's rank correlation, and multiple regression analysis. Results: The average age of the donors was $35.7{\pm}12.2$ years, and all donors were family members. PCA was applied for control pain in all patients, and 40.7% of PCA-related side effects were observed. The average length of hospital stay was $9.24{\pm}2.52$ days. The factors influencing the length of hospital stay were operative methods, pain control methods, and postoperative complications. The length of hospital stay was 1.29 days shorter if donors had no complication, 1.43 days shorter when only PCA was used, and 1.19 days shorter when laparoscopic resection was performed (Adjusted $R^2=0.17$, F=4.67, p<.05). Conclusion: The results of this study can be used as basic data for practical and effective postoperative nursing education and intervention of living liver donors.

PRELIMINARY OPTICAL DESIGN OF MIRIS, MAIN PAYLOAD OF STSAT-3 (과학기술위성3호 주탑재체 MIRIS의 광학계 시험설계)

  • Yuk, I.S.;Jin, H.;Lee, S.;Park, Y.S.;Lee, D.H.;Nam, U.W.;Park, J.H.;Han, W.Y.;Lee, J.W.
    • Publications of The Korean Astronomical Society
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    • 제22권4호
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    • pp.201-209
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    • 2007
  • We have preliminarily designed two infrared optical systems of the multi-purpose infrared camera system (MIRIS) which is the main payload of STSAT-3. Each optical system consists of a Cassegrain telescope, a field lens and a 1:1 re-imaging lens system that is essential for providing a cold stop. The Cassegrain telescope is identical for both of two infrared cameras, but the field correction lens and re-imaging lens system are different from each other because of different bands of wavelength. The effective aperture size is 100mm in diameter and the focal ratio is f/5. The total length of the optical system is 300mm and the position of the cold stop is 25mm from the detector focal plane. The RMS spot size is smaller than $40{\mu}m$ over the whole detector plane.

Analysis of the Damage Patterns and Metal Structure of 3 Phase Mold Transformers to which Interlayer Short-circuits have Occurred (층간 단락된 3상 몰드변압기의 소손 패턴 및 금속 조직 해석)

  • Choi, Chung-Seog
    • Journal of the Korean Society of Safety
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    • 제25권6호
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    • pp.86-91
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    • 2010
  • The purpose of this study is to analyze the damage patterns and metal structure of 3 phase mold transformers collected from places where accidents have occurred. Compared to an oil-immersed transformer, a mold transformer has the advantage of requiring a smaller installation area and can be kept clean, while its disadvantages include the fact that abnormal symptoms of an accident are difficult to discover and its repair is impossible. The capacity of the mold transformers collected from places where accidents have occurred was 200kVA with primary voltages being F23,900V, R22,900V, 21,900V, 20,900V, 19,900V, etc., as well as secondary voltages being 380V, 220V, etc. It was found from the analysis on the diffusion of combustion in the damaged mold transformers that fire occurred first inside the U-phase primary winding and that carbonization and heat were diffused to V-phase and W-phase in V-pattern. In addition, from the analysis on the cross-sectional structure of the metal of the melted high voltage winding using a metallurgical microscope, it was found that the boundary surface, voids, and columnar structure were formed when an interlayer short-circuit had occurred Therefore, even though it is not possible to find the cause for the occurrence of an interlayer short-circuit at the inner side of the primary winding, it is thought that, due to the thermal energy generated when the short-circuit occurred, the heat source was diffused to the upper side and outside, causing a secondary accident.

21세기 유럽 해항도시의 롤 모델로서의 하펜시티 함부르크

  • Jeong, Jin-Seong;Jo, Hyeon-Cheon
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 한국항해항만학회 2011년도 춘계학술대회
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    • pp.376-378
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    • 2011
  • Hamburg is going with the HafenCity Project to create new urban space for city's bustling central district. HafenCity will add an additional 155 hectares to Hamburg's central urban area, increasing its total area by some 40 percent. The new developments in HafenCity will be oriented towards the River Elbe and the great seaport. Its centre will have a close relation to water. They will be used for the construction of a fascinating mix of residential accommodation, offices, cultural and leisure amenities, retail facilities and restaurants set in a framework of an elaborate urban layout. This study is focusing on the purpose of the project goals, the task of the Hamburg authorities and GHS (Gesells chaft f$\ddot{u}$r Hafen und Standortentwicklung) and an urban planning ideas competition (draft masterplan). Regarding of the new trend of the reurbanisation in Europe, the aim of this study will be to find out, in which way Hafencity is trying to develope the new city district as a model for the European inner city of the 21st century.

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THE STUDY OF PATIENT EXPOSURE AND PROTECTION FROM DENTAL RADIOGRAPHY (치과 X선 촬영에 있어서 환자에 대한 피폭과 방어에 관한 연구)

  • Park T. W.
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • 제9권1호
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    • pp.25-31
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    • 1979
  • The utilization of x-ray for diagnosis and examination is increasing by about 5-15% every year, therefore, it would be mandatory to protect the patients from exposures and so, studies in this field are performed even now. In dental field, the area of irradiation is limited any to the head and neck area, but the irradiated angle is varied following the objected tooth, so the adjacent structures lens and thyroid gland would be fragile to radiation. And the scattered radiation is one of the complicated problems in the protection because of specificity of dental x-ray and its object structures. The author, by using TLD (Thermo luminescent Dosimeter; Teledyne Isotopes-Model 7300, Element; TLD 200(CaF₂:Dy) and Capintec(Capintec Model 192, PM-30 Diagnostic chamber 28㎖ active volume), tried a measurement of air dose distribution of the scattered radiation and the irradiated dose of lens and thyroid gland under the condition of taking the film on the left maxillary molar. The results were as follows: 1. The half value layer of adapted dental x-ray machine was measured, and is 1.44㎜ Al. 2. The time of irradiation on the left maxillary molar in the Alderson Rando Phantom, the measured doses of left and right lens, and thyroid gland were 8,9mR, 1,2mR and 2,8mR. Under the same conditions, the scattered radiation at the distance of 1 meter from the phantom were 84 μR at the front side, 11μR at the back side, 18μR at the right side and 72μR at the left side. 3. Under the same conditions, the dose showed higher value by about 5% in the presence of object(phantom) than in the case of absence.

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고립된 왜소불규칙은하 NGC 1156의 새로운 거리 결정

  • Kim, Sang-Cheol;Park, Hong-Su;Gyeong, Jae-Man;Lee, Jun-Hyeop;Lee, Chang-Hui;Kim, Min-Jin
    • The Bulletin of The Korean Astronomical Society
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    • 제37권2호
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    • pp.80.2-80.2
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    • 2012
  • 홀로 고립되어 존재하는 은하는 주변 은하와 상호작용을 하지 않은 채 진화하므로 은하의 진화를 연구하기에 아주 좋은 대상이다. 은하의 정량적 연구를 위해 꼭 알아야 하는 중요한 물리량으로 거리와 성간소광량이 있다. 우리는 허블 우주망원경(HST) Advanced Camera for Surveys(ACS)/High Resolution Channel(HRC)로 관측한 고립된 왜소불규칙은하 NGC 1156 ($RA_{2000}$=02:59:42.19, $DEC_{2000}$=+25:14:14.2) 중심부($26^{\prime\prime}{\times}29^{\prime\prime}$)의 archive 자료를 분석하여 이 은하의 거리와 성간소광량을 새로 구했다. 이 은하의 거리를 측정한 과거 자료는 Tully(1988, Nearby Galaxies Catalog) 목록과 Special Astrophysical Observatory 6m 망원경/VI(각 300s) 영상자료의 가장 밝은 별로 거리를 구한 Karachentsev et al. (1996) 자료 뿐이다. 우리는 HST/ACS/HRC+UBVI 자료 중 U자료를 이용하여 아주 신뢰할 만한 소광량 값($E(B-V)=0.35{\pm}0.05$)을 얻었고, 가장 밝은 빨간 별과 파란 별 자료를 이용하여 새로운 거리지수($(m-M)_0=29.39{\pm}0.20$, $d=7.6{\pm}0.7$ Mpc)를 결정했다. 이 거리 값은 과거의 값들(Tully $6.4{\pm}1.2$ Mpc; Karachentsev et al. $7.8{\pm}0.5$ Mpc)과 크게 다르지 않으며, 기존의 거리 자료들 역시 신뢰할만함을 보여준다. ACS/Wide Field Channel과 달리 ACS/HRC의 경우 등급 표준화 방정식이 완벽하지 않은데, 우리의 경우 F550M자료를 표준화할 수 없었다. 그러나 우리는 여러 파장, 많은 관측자료가 존재하는 47 Tucanae (NGC 104) 구상성단의 관측자료와 Padova 등연령곡선을 이용하여 성공적인 등급변환을 수행할 수 있었다.

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Evaluation of the KN-12 Spent Fuel Transport Cask by Analysis

  • Chung, Sung-Hwan;Lee, Heung-Young;Song, Myung-Jae;Rudolf Diersch;Reiner Laug
    • Nuclear Engineering and Technology
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    • 제34권3호
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    • pp.187-201
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    • 2002
  • The KN-12 cask is designed to transport 12 PWR spent nuclear fuels and to comply with the requirements of Korea Atomic Energy Act, IAEA Safety Standards Series No.57-1 and US 10 CFR Part 71 for a Type B(U)F package. It provides containment, radiation shielding, structural integrity, criticality control and heat removal for normal transport and hypothetical accident conditions. W.H 14$\times$14, 16$\times$16 and 17$\times$17 fuel assemblies with maximum allowable initial enrichment of 5.0 wt.%, maximum average burn-up of 50,000 MWD/MTU and minimum cooling time of 7 years being used in Korea will be loaded and subsequently transported under dry and wet conditions. A forged cylindrical cask body which constitutes the containment vessel is closed by a cask lid. Polyethylene rods for neutron shielding are arranged in two rows of longitudinal bore holes in the cask body wall. A fuel basket to accommodate up to 12 PWR fuel assemblies provides support of the fuels, control of criticality and a path to dissipate heat. Impact limiters to absorb the impact energy under the hypothetical accident conditions are attacked at the top and at the bottom side of the cask during transport. Handling weight loaded with water is 74.8 tons and transport weight loaded with water with the impact limiters is 84.3 tons. The cask will be licensed in accordance with Korea Atomic Energy Act 3nd fabricated in Korea in accordance with ASME B&PV Code Section 111, Division 3.

The effect of Natural Antimicrobial Agent (천연 물질의 항균 효과)

  • 조춘구;한창규
    • Journal of the Society of Cosmetic Scientists of Korea
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    • 제25권3호
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    • pp.87-99
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    • 1999
  • Manuka oil named New Zealand’s tea tree oil is oil-soluble and comes firom nature. Manuka oil and its extract $\alpha$-pinene, Oxy’less clear, R-limonene which is one of the component of Citron extracted from Grapefruit seed and Citrex were used to estimate the antimicrobial activity and to improve the capability of antiseptic. Disk diffusion method was used to measure the antimicrobial activity. Escherichia coli which is gram-negative bacteria and Staphylococcus aureus which is gram-positive bacteria were used as strain. The antimicrobial activity of Manuka oil and $\alpha$-pinene for Escherichia coli, Staphylococcus aureus was similar when the concentration of Manuka oil and $\alpha$-pinene are 10u/paper disk. However, antimi-crobial activity of Manuka oil fDr Escherichia coli, Staphylococcus aurem was better than that of $\alpha$-pinene when the concentration of Manuka oil and $\alpha$-pinene was low. Antimicrobial activity of Oxy’less clear is better than that of propyl para hydroxybenzoate(PPHB), R-limonene at all the concentration and is similar to that of $\alpha$-pinene. Antimicrobial activity.

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Isolation and Characterization of Allelopathic Substances from Sorghum Stem (수수 줄기에 함유(含有)된 타감물질(他感物質)의 분리(分離) 및 특성(特性) 구명(究明))

  • Kim, S.Y.;De Datta, S.K.;Robles, R.P.;Kim, K.U.;Lee, S.C.;Shin, D.H.
    • Korean Journal of Weed Science
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    • 제14권2호
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    • pp.156-162
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    • 1994
  • To better understand the exact nature of the major toxic compound responsible for phytotoxicity of sorghum stem, the most toxic compound from the stem extract was isolated by rapid chromatography and subsequently purified by thin-layer chromatography(TLC) and high pressure liquid chromatography(HPLC). Of the eight fractions isolated by rapid chromatography, the fraction with solvent combinations of butanol (8) : acetic acid (1) : water (1) had the highest toxicity. Further separation of the fraction by TLC in a solvent mixture of butanol (24) : acetic acid (16.4) : water (7) : propanol (1) showed that the spot with an $R_f$ 0.71 had one major peak with retention time of 20.40 minutes. Upon subjecting gas chromatography and the HPLC fraction to the mass spectrometry, the toxic compound is probably one of the four compounds ; 1-methyl-1-(2-propynyl)-hydrazine, 1-aziridineethanol, 5-chloro-2-pentanone, and 2-(methylseleno)-ethanamine.

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