• 제목/요약/키워드: Two stage approach

검색결과 554건 처리시간 0.031초

디지털 흉부영상에서 주성분분석을 이용한 폐암인식 (Recognition for Lung Cancer using PCA in the Digital Chest Radiography)

  • 박형후;옥치상;강세식;고성진;최석윤
    • 한국정보통신학회논문지
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    • 제15권7호
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    • pp.1573-1582
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    • 2011
  • 흉부의 폐질환으로 폐암발생은 꾸준히 증가하고 있다. 일차적인 폐암진단 방법에는 흉부X선영상이다. 흉부X선영상 이용하여 폐암진단을 하기 위해서는 임상경험이 풍부한 의사가 필요하다. 그러나 풍부한 경험을 가진 의사라도 오진이 발생할 수 있고 이한 폐암의 조기진단과 생존률을 낮게 한다. 본 논문에서는 주성분분석을 이용하여 학습영상의 데이터베이스와 질병이 있는 흉부영상을 진단함으로써 컴퓨터보조진단의 기반을 마련하고자 한다. 이를 의사가 진단하기 전의 예비판독의 단계로 이용한다면 오진으로 인한 환자의 조기 진단률의 감소를 줄일 수가 있다. 실험은 정상흉부X선영상과 악성폐암인 기관지암(Bronchogenic Carcinoma)과 양성종양인 육아종(Granuloma)으로 실험하였다. 영상은 주성분분석 후 정상영상과 질환 영상의 고유영상을 추출하고 상호 비교한 뒤 인식효율을 비교하였다. 결과로는 정상영상과 질환영상간의 인식률은 높았으나 질환간의 인식효율은 정상에 비해 다소 떨어지는 것으로 나타났다. 흉부질환간의 인식효율을 높이기 위해서 관련 알고리즘에 관한 연구가 계속 이어진다면 컴퓨터보조진단에 좋은 연구기반이 되리라 생각한다.

중국에서의 소셜 커머스 특성과 소비자 특성이 재구매의도에 미치는 영향 (The Effects of Repurchase Intention by Social Commerce Traits and Consumer's Traits in China)

  • 무윤택;이종호
    • 유통과학연구
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    • 제14권5호
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    • pp.97-106
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    • 2016
  • Purpose - Social commerce is a certain way of how people buy some products together with others through the internet sites with mutual interactions among customers with the benefits of SNS when buying some products. At present, China market has some problems due to its rapid growing. However, empirical research or academic approach to social commerce has not been made enough. So, it is important for Chinese social market to develop and enlarge the customers with stability under the reliability and satisfaction. Also it is important for them to have repurchase intention. Nowadays, it is necessary to find the factors on customer satisfaction and trust, whereas consumers' dissatisfaction and unreliability are increasing on social commerce recently. In addition, researches on social commerce have been actively pursued by a variety of domestic and foreign scholars. However, researches on social commerce and Chinese market are short of, and they have some limitations because of the rapid growth of the market even though it is the early stage. The current situation requires researches on consumers' repurchase intention for continuing growth in the future according to the growth of Chinese social commerce. Research design, data, and methodology - The literature and the empirical studies are combined in order to achieve the purpose of the study. Deriving social commerce features and consumer properties as factors affecting the repurchase intention through the literature, and these factors have modeled a series of assumptions about the impact on satisfaction and trust, and have established hypotheses to verify them. The survey which is conducted to test the hypothesis and questionnaires are derived based on the variables discussed in the previous study. Appropriate measures were developed and tested on 227 respondents in China with a cross-sectional questionnaire survey. The path relationships of the research model were analyzed by SPSS 23.0 and Amos 23.0. Results - Research results about social commerce characteristics and factors affecting the repurchase intention are presented to Chinese market companies that adopt business models and consumer characteristics. In addition, this study focuses on the characteristics of social commerce, from two-dimensional characteristics of the consumer satisfaction, trust and the impact on the repurchase. Therefore, social commerce features and consumer properties based on the results of this study may lead the strategic implications that may increase the repurchase intention. Conclusions - The classification reviewing the previous findings related to social commerce and social commerce features affects social commerce repurchase (price discount, interactivity) and consumer characteristics (impulsivity, innovation, collectivism). It affects repurchase on factors and analyzes empirically. The empirical results identify major characteristics (social commerce characteristics, attributes) that affect the repurchase intention, and give the practical implications as well as the business strategies that are able to enhance social commerce repurchase consumers. Social commerce is a certain way of how people buy some products together with others through the internet sites with mutual interactions among customers with the benefits of SNS when buying some products.

선화아연바리스터 기반의 1-포트 서지보호장치의 최적 설계 기법 (Optimal Design Method of 1-Port Surge Protective Device Based on Zinc Oxide Varistor)

  • 정태훈;김용성;박근보;이승일
    • 한국산학기술학회논문지
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    • 제19권4호
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    • pp.93-102
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    • 2018
  • 본 논문은 뇌격전류에 따른 저압 배전계통의 전자식 전력량계 및 배전 패널의 통신설비와 전원장치를 보호할 목적으로 사용하는 서지보호장치(SPD)에 관한 것이다. 서지보호장치(SPD)는 접속방식에 따라 1-포트 서지보호장치(SPD)와 감결합 요소를 포함한 2-포트 서지보호장치(SPD)로 구분된다. 뇌격전류에 대한 내부 시스템의 보호는 협조된 서지 보호체계를 이루는 계통적인 접근이 필요하다. 이에 대응하기 위해 이론적인 검토를 통해 피뢰구역(LPZ) 정의에 대한 고찰 및 해석을 진행하였다. 뇌서지에 의한 뇌격전류는 상당히 크기 때문에 하나의 서지보호장치(SPD)로 방호하기에는 한계가 발생하며, 이를 해결하기 위해 다단의 종속적으로 서지보호장치(SPD)를 설치하게 된다. 본 논문에서는 전력계통에 있어 한전계통에 연계되는 Incoming side가 아닌 건물 내에 설치되는 분기형 배전패널 내부의 전자식 전력량계 및 각종 통신(제어)설비를 보호할 목적으로 한전계통이 연계되는 MOF 단에 설치되는 LPZ0에 해당하는 피뢰기(LA, SA)와 보호협조를 이루는 LPZ1과 LPZ2의 경계영역에 설치하는 저압 배전계통용 II등급 서지보호장치(SPD)에 대해 설계를 하였다. 또한 감결합 요소가 없고, 부하 전류를 흘릴 수 있는 직렬 접속 방식의 1-포트 서지보호장치(SPD)에 대한 최적의 설계 방안을 도출하고 실험을 통해 기존의 방식과 비교하여 성능 개선과 관련한 검증을 실시하였다.

Large-scale Culture of Plant Cell and Tissue by Bioreactor System

  • Son, Sung-Ho;Park, Sung-Mee;Park, Seung -Yun;Kwon, Oh-Woung;Lee, Yun-Hee;Paek, Kee-Yoeup
    • Journal of Plant Biotechnology
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    • 제1권1호
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    • pp.1-7
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    • 1999
  • Large-scale cultures of plant cell, tissue, and organ have been achieved by using BTBB. When different sized BTBBs (5 L, 20 L, 100 L, 300 L, and 500 L) were tested for the culture of yew cells (Taxus cuspidata Sieb. et Zucc.), cell growth increment reached to 94.5% in SCV after 24 days of culture with 30% of inoculation cell density. However, there were some variations in the production of taxol and its derivatives among the BTBBs of different size. Approximate 4 ㎎/l of taxol and 84 ㎎/l of total taxanes were obtained by using a 500L BTBB after 6 weeks of culture. With a 20L BTBB, about 20,000 cuttings of virus-free potatoes (cv. Dejima) could be obtained by inoculating 128 explants and maintaining 8 weeks under 16 hr light illumination. The frequency of ex vitro rooting of the cuttings revealed as more than 99% under 30% shade. By incorporating two-stage culture process consisting of multiple bulblet formation in solid medium and bulblet development in liquid medium, mass propagation of lily through bioreactor seemed to be possible. In the case of 'Marcopolo', the growth of mini-bulblets in BTBB was nearly 10 folds faster than that of the solid medium. Time course study revealed that maximum MAR yield of ginseng (Panax ginseng C. A. Meyer) in a 5 L and 20 L BTBB after 8 weeks of culture was 500 g and 2.2 ㎏, respectively. By cutting the MAR once and/or twice during the culture, the yield of root biomass could be increased more than 50% in fresh weight at the time of harvest. With initial inoculum of 500 g of sliced MAR in a 500 L BTBB, 74.8 ㎏ of adventitious root mass was obtained after 8 weeks of culture. The average content of total ginseng saponin obtained from small-scale and/or pilotscale BTBBs was approximately 1% per gram dry weight. Based on our results, we suggest that large-scale cultures of plant cell, tissue, and organ using BTBB system should be quite a feasible approach when compared with conventional method of tissue culture.

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Simultaneous Modulated Accelerated Radiation Therapy and Concurrent Weekly Paclitaxel in the Treatment of Locally Advanced Nasopharyngeal Carcinoma

  • Xie, Cong-Ying;Jin, Xian-Ce;Deng, Xia;Xue, Sheng-Liu;Jing, Zhao;Su, Hua-Fang;Wu, Shi-Xiu
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권12호
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    • pp.6129-6132
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    • 2012
  • Objectives: To evaluate the feasibility and efficacy of simultaneous accelerated radiation therapy (SMART) and concurrent weekly paclitaxel in the treatment of locally advanced nasopharyngeal carcinoma. Methods: Forty-one patients with pathologically confirmed nasopharyngeal carcinoma were treated by SMART with concurrent weekly paclitaxel. Daily fraction doses of 2.5 Gy and 2.0 Gy were prescribed to the gross tumor volume (GTV) and clinical target volume (CTV) to a total dose of 70 Gy and 56 Gy, respectively. Paclitaxel of $45mg/m^2$ was administered concurrently with radiation therapy every week. Adjuvant chemotherapy was given four weeks after the completion of the radiotherapy (RT) if the tumor demonstrated only a partial response (PR). Results: All patients completed the radiotherapy (RT) course. Adjuvant chemotherapy was administered to 12 patients due to PR. The CR (complete remission) rate was 82.9% three months after RT. Thirty-nine (95.1%) patients completed the concurrent weekly chemotherapy with paclitaxel, and two patients skipped their sixth course. Seven patients had a 15% dosage reduction at the fifth and sixth course due to grade 3 mucositis. The median follow-up was 30 (range, 14-42) months. The three-year overall survival (OS), metastases-free survival (MFS), and local control rates were 77.0%, 64.4%, and 97.6%, respectively. No correlation between survival rate and T or N stage was observed. Grade 3 acute mucositis and xerostomia were present in 17.1% and 7.1%, respectively. Conclusion: SMART with concurrent weekly paclitaxel is a potentially effective and toxicity tolerable approach in the treatment of locally advanced NPC.

Research on legal improvement measurements on drone use

  • Park, Jong-Ryeol;Noe, Sang-Ouk
    • 한국컴퓨터정보학회논문지
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    • 제22권3호
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    • pp.147-153
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    • 2017
  • The main subject of year 2016 Davos forum was "The 4th Industrial Revolution." Recently, interests and investment in drone market, so called industrial revolution in the sky is growing in many countries around the world. Before, drone was used for military purpose such as reconnaissance or attacking but today, it is used in various private sectors such as unmanned delivery service, agriculture, leisure activities, etc. Presently, many major countries in the world are already involved in the 'war without gunfire' to be dominant in this drone industry. Korean government also has announced an extreme relaxation of regulations for growing drone industry by opening a conference with Ministers related to economics. During the conference, business scope of drone which was limited to agriculture, photographing, and observation was expanded to all the fields except for cases hindering national safety and security. In terms of shooting purpose drone its process of receiving approval for flight and shooting is simplified to online registration. What is more, drone delivery service will be allowed in island areas such as Goheung, Yeongwol, etc from first term of year 2017. Finding the way to apply drone in criminal investigation is also speeding up. Recently, Public Safety Policy Research Center in Korean National Police University has inquired for research service and its result will be out around November. Likewise, although more and stronger foundation for supporting drone industry is made but there are still, some opinions saying that we should take a careful approach in consideration to the side effect such as abuse in crime. One may also try terror by placing a dangerous substance. If drone falls, it may hurt any civilians. Moreover, if shopping purpose drone is hacked, it may result in violation of privacy. Compared to America, Europe, and China, we are at the very beginning stage of drone industry and it is necessary to reorganize legal issues to grow this industry. This can be thought from two perspectives; first, the growth of drone industry is blocked by difficult regulations on Aviation Law and Radio Regulation Law. The second issue is the safety and privacy that are required for operating drone. For the advanced technologies to make human life more profitable, more active and proactive actions are required by criminal law side. In preparation to the second mechanical era where man and machines should go together, I hope that responsible preparation is required in all fields including the criminal law.

Different expression levels of OsPLS1 control leaf senescence period between indica and japonica-type rice

  • Shin, Dongjin;Kim, Tae-Hun;Lee, Ji-Yun;Cho, Jun-Hyeon;Song, You-Chun;Park, Dong-Soo;Oh, Myeong-Gyu
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.98-98
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    • 2017
  • Leaf senescence is the process of aging in plants. Chlorophyll degradation during leaf senescence has the important role translocating nutrients from leaves to storage organs. The functional stay-green with slow leaf yellowing and photosynthesis activity maintenance has been considered one of strategy for increasing crop productivity. Here, we have identified two QTLs on chromosome 9 and 10 for leaf senescence with chlorophyll content of RIL population derived from a cross between Hanareum 2, early leaf senescence Indica-type variety, and Unkwang, delayed leaf senescence Japonica variety. Among these QTLs, we chose qPLS1 QTL on chromosome 9 for further study. qPLS1 was found to explain 14.4% of the total phenotypic variation with 11.2 of LOD score. Through fine-mapping approach, qPLS1 QTL locus was narrowed down to about 25kb in the marker interval between In/del-4-7-9 and In/del-5-9-4. There are 3 genes existed within 25kb of qPLS1 locus: LOC_Os09g36200, LOC_Os09g36210, and LOC_Os09g36220. Among these genes, transcript level of LOC_Os09g36200 was increased during the leaf senescence stage and the expression level of LOC_Os09g36200 in Indica was higher than in Japonica. Finally, we chose LOC_Os09g36200 as candidate gene and renamed it as OsPLS1-In and OsPLS1-Jp from Indica- and Japonica-type rice, respectively. OsPLS1-In and OsPLS1-Jp overexpressing transgenic plants showed both early leaf senescence phenotype. These results indicate that OsPLS1 functions in chlorophyll degradation and the difference of expression level of OsPLS1 cause the difference of leaf senescence between Indica and Japonica in rice.

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노인의 의미에 대한 주관성 연구 (A Subjectivity Study on the Meaning of Aging for Elders)

  • 이금재;박인숙;김분한
    • 기본간호학회지
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    • 제7권2호
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    • pp.271-286
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    • 2000
  • This study is designed to investigate what elders think about the meaning of aging. We have used Q-methods to identify meaning of aging from elders, and developed self-referenced surveys to analyze characteristics In this study, we used a non-structured method to select Q sampling. From 183 Q populations, we selected 36 Q sampling. A total of 32 persons sixty-years or older were randomly selected for P samples, When the Q-sorting was complete, we interviewed the participants at both end of the extremes(agree or disagree), and documented their responses. We used PC QUANL to process the data and used principal component analysis for Q factor analysis. There were five subjective types for the meaning of aging by elders. Of the 32 P-samples of elders, 11 were identified as Type 1, 7 as Type 2, 2 as Type 3, 8 as Type 4, and 4 as Type 5. Type 1 : 'Matured elders' Elders wished the well being of their children, thought older persons should maintain good health, worried about becoming senile, and dependent God believing in life after death. Type 2 : 'Assertive-Rights' Elders categorized as Assertive-Rights insisted on their rights to life as a person. Type 2 elders characterized themselves as people who should keep themselves healthy, become weak and lack sexual desires, act selfish like a child, need to be protected, and be financially independent. Type 3 : 'Passive-Dependents' Elders characterize themselves as those who pray for their children's well being, worry about the children even after their death. and becoming senile. Type 4 : 'Hopeless' The 'Hopeless' type of elders characterized aging as a time to pray for their children, insignificant beings, thoughts were selfish and child-like, poor, worried about going senile, regret their life overall, and preferred to die than to live as an old person. Type 5 : 'Attached-Present' The 'Attached-Present' type of elders thought elderly characterized themselves as acting selfish and child-like, wiser, anxious, regret their life, stand aloof of greed and worldly things, being a model for the society, and deserving to be treated with filial respect. Thus far, Korean elders seemed to have a positive and negative meaning of aging due to the current changes in the society, value system, and family structures. The above five subjective meanings of aging confirm that we need to approach and nurse the elderly differently. Years of aging are a part of and a natural process of life with various physical, psychological, and sociological changes. Nurses need to assist elderly to find the positive meaning of their life by providing appropriate physical, psychological, and social support at an earlier stage in nursing. Based on this study, we could derive the following two implication from the perspectives of science of nursing to care for elders. 1) Based on the studies investigating the type of meaning of aging, we could develop tools to assist in nursing intervention programs for elderly. 2) Based on research on the meaning of aging for different developmental stages of life, we could develop a model for roles for different family members in nursing and caring for the elders.

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수의전문직업성 측면에서 본 수의과대학 학생의 학습윤리 (A Matter of Professionalism: Academic Misconduct of Veterinary Students)

  • 천명선;류판동;윤정희
    • 한국임상수의학회지
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    • 제32권2호
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    • pp.174-179
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    • 2015
  • 정직성과 신뢰는 수의사의 전문직업성(professionalism)을 구성하는 핵심요소일 뿐만 아니라, 수의학교육에서는 수의학 전문교육 결과의 정당성을 보장하는 근거가 되는 중요한 가치이다. 의학교육에서는 의과대학에서의 학습부정 경험이 추후 의사로서 일할 때 발생하는 비윤리적인 행위와 관련이 있다고 밝혀져 있다. 본 연구에서는 서울시내 수의과대학 학생 528명(A대학: 184명, B대학: 344명)의 학습부정과 학습윤리에 대한 태도를 조사하여 분석하였다. 학생들은 학습윤리가 향후 학문윤리에 중요한 영향을 미칠 수 있다고 평가하였다(88.4%). 가장 흔하게 발견되는 학습부정행위는 보고서 작성시 표절(A대학: 71.7%, B대학: 69.5%)과 실습 시 데이터 위조행위(A대학: 40.2%, B대학: 31.7%) 등이었으며, 학생들은 학교 내 학문윤리 문화의 부재가 학습부정행위의 원인이 된다고 지적하였다. 회귀분석 결과 학습윤리에 대한 지식과 동료 학생들의 학습부정행위에 대한 인식이 수의과대학 학생들의 학습부정행위 빈도에 영향을 미치는 것으로 나타났다. 본 연구 결과를 통해 수의과대학 학생들의 학습윤리 교육이 저학년부터 전 과정에 거쳐 보다 유연한 형식의 프로그램으로 진행되어야 하며, 교수진과 학문 커뮤니티의 학문윤리 환경 조성이 중요하다는 점을 도출하였다.

자연기흉에 대한 Thoracoscopy 의 임상적의의 (Clinical Significance of Thoracoscopy on Spontaneous Pneumothorax)

  • 김영태;김근호
    • Journal of Chest Surgery
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    • 제8권1호
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    • pp.19-28
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    • 1975
  • The thoracoscopic study was reported on 21 cases of spontaneous pneumothorax requiring surgical management, and clinical values of thoracoscopic examination on spontaneous pneumothorax were also discussed. patients were treated in the Department of .Thoracic Surgery, Hanyang University Hospital for the period of two Years from May 1972 to April 1974. For exact detection of etiologic factors on spontaneous pneumothorax, the thoracoscopic examination in the intrapleural space was performed in parallel with X-ray study. this study, the difference of diagnostic and therapeutic significance between radiological and thoracoscopic findings were observed and compared simultaneously. The results are summerized as follows: Patients age was distributed between 3 and 70 years old with highest incidence in the age group of sixty decade [33. 3%], and sex ratio of male to female was 5:2. The tuberculous processes which developed superficial subpleural layer in the lung parenchyme, on the pulmonary surface could be observed by thoracoscopic examination in a characteristic picture. detection ratio of pulmonary tuberculosis by the radiologic study to that by thoracoscopy was 8:2. The adhesion between the visceral and the parietal pleura which could possibly make a rupture of the alveola and the visceral pleura was found to be localized in a small area of the lung surface. The other part of the lung surface was free of the adhesion and, therefore, the movement of the lung took place completely without any difficulty. The ruptured orifice of the pleura and pathological changes surrounding the orifice can be detected by thoracoscopy, but not by other means such as radiologic examination. A single tuberculous bleb and multiple emphysematous blebs were found on 6 cases out of 21 cases of spontaneous pneumothorax. Among these cases, radiologic Study revealed the bleb only in one patient. On the other hand, the blebs were found in all the six patients by means of thoracoscopic examination. It gives the detection ratio of bleb by radiologic study to that by thoracoscopy was 1:6. By thoracoscopy, the rupture on the lung surface were visualized on the 10 patients out of a total of 21 patients [10 patients of visual rupture]. However, the rupture of the pleura was not observed on the rest of 11 patients even by thoracoscopic examination [11 patients of non visual rupture]. Five patients [50%] out of ten who had the visual rupture on the lung surface was required a surgical operation to remove pneumothorax. For the patients who were detected to have the visual rupture of the pleura by thoracoscopy, be considered in the early stage of closed thoracostomy. of 21 patients, 16 patients [11 patients of non visual rupture of the pleura and 5 patients of visual rupture of the pleura] who received no surgical management, were treated with closed thoracostomy with continuous suction, and the` pneumothorax was healed completely up in each cases. Therapeutic measures for the remaining 5 patients of visual rupture of the pleura who were subjected to surgical approach for radical treatment of spontaneous pneumothorax were accordingly complicated, and the following different procedures were properly indicated case by case, that is, rib resection thoracostomy, simple closure of ruptured visceral pleura, wedged resection of the lung, and lobectomy.

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