• Title/Summary/Keyword: Two Agent

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Comparison of two diagnostic methods, allele-specific real-time PCR and 3'-tailed PCR to discriminate between Salmonella enterica serovars Gallinarum and S Pullorum (Salmonella enterica serovars Gallinarum과 S Pullorum의 감별을 위한 2가지 진단법: allele-specific real-time PCR과 3'-tailed PCR의 비교)

  • Lee, Se-Mi;Seo, Ja-Young;Lee, Jae-Il;Kim, Tae-Jung
    • Korean Journal of Veterinary Service
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    • v.31 no.4
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    • pp.485-492
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    • 2008
  • Salmonella enterica serovars Gallinarum(SG, causative agent of fowl typhoid) and S Pullorum(SP, causative agent of pullorum disease) are very important bacterial pathogens in poultry industry. They share some common antigenic properties though the characteristics of outbreaks are quite different. To discriminate between SG and SP, we developed two rapid diagnostic methods, allele-specific real-time PCR and 3'-tailed PCR over 2 single nucleotide polymorphisms ($237^{th}\;and\;598^{th}$). In both methods, $237^{th}$ allele was found to be a good target for differential diagnosis, while $598^{th}$ allele produced some non-specific reactions.

Reverse Logistics in the E-Marketplace Supply Chain: A Two-Stage Return and Recycling Policy (전자상거래 공급망의 회수물류: 재활용을 고려한 이단계 반품정책)

  • Yoo, Seung-Ho
    • Journal of the Korean Operations Research and Management Science Society
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    • v.35 no.4
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    • pp.17-31
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    • 2010
  • This study investigates two-stage return policy and recycling issues in an e-marketplace supply chain consisting of consumers, a retailer and a manufacturer. The manufacturer, a focal company in the e-marketplace supply chain, considers the recycling of commercial returns so offers the retailer a buy-back contract of which transfer payment consists of a wholesale price and a buy-back price. Then, under the given contract offer, the retailer determines a selling price and a return policy to control consumers' demand and return requests. We consider the retailer's opportunistic behavior and supply chain coordination issues based on the principal-agent paradigm. We compare the first-best and second-best optima and conduct comparative static analyses to evaluate the performance results of the buy-back contract and provide important managerial implications.

A Systematic Study on MR Contrast Agents for Constructing Specific Relaxation Times

  • Cho, Jang-Geun;Cho, Jee-Hyun;Lee, Chul-Hyun;Ahn, Sang-Doo
    • Journal of the Korean Magnetic Resonance Society
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    • v.14 no.1
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    • pp.9-17
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    • 2010
  • The water proton relaxation rates increase linearly with concentrations of contrast agents, and could be expressed as a function of the concentrations. In this paper, we have investigated MR properties of two different contrast agents, $GdCl_3$ and $CoCl_2$. Relaxivity coefficients were calculated from individual contrast agent solutions, and used for predicting relaxation rates at mixtures of two contrast agents. From the experimental results, we have discussed the feasibility of constructing water solutions with the desired relaxation times using specific mixtures of contrast agents.

Echo-PIV: in vivo Flow Measurement Technique (에코 PIV: in vivo 유동 측정기법)

  • kim Hyoung-Bum;Hertzberg Jean;Shandas Robin
    • Journal of the Korean Society of Visualization
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    • v.3 no.1
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    • pp.26-35
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    • 2005
  • The combination of ultrasound echo images with digital particle image velocimetry (DPIV) method has resulted in a two-dimensional, two-component velocity field measurement technique appropriate for opaque flow conditions including blood flow in clinical applications. Advanced PIV processing algorithms including an iterative scheme and window of offsetting were used to increase spatial resolution. The optimum concentration of the ultrasound contrast agent used for seeding was explored. Velocity validation tests in fully developed laminar pipe flow and pulsatile flow showed good agreement with both optical PIV measurements and the known analytic solution. These studies indicate that echo PIV is a promising technique for the non-invasive measurement of velocity profiles and shear stress.

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Purification and Properties of Biosurfactant from Pseudomonas aeruginosa KK-7 (Pseudomonas aeruginosa가 생산하는 biosurfactant의 분리 및 특성)

  • 김대원;김민주;강상모
    • Microbiology and Biotechnology Letters
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    • v.23 no.3
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    • pp.337-345
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    • 1995
  • Biosurfactants produced by Pseudomonas aeroginosa KK-7 were purified and their properties were studied. The bacterial surfactant was seperated into two sorts of biosufactants (Type I, 11) by silica gel column chromatograpgy. On the basis of physiochemical analysis, Type I was found to be mixture of two glycolipids with M.W. 800, and Type II was peptide with M.W. 1300. The Type 11 biosurfactant was compose of glutamic acid, proline, glycine, leucine, histidine. The crude extract was used to dertermine some properties as a surfactant. The biosurfactant had the properties as stronger emulsification agent and a stronger stabilizing agent emulsion than any other surfactants tested.

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Mobile IP QoS Provisioning in Two Level Architecture (Two Level Architecture를 이용한 Mobile IP QoS 보장 기법)

  • Seo, Jeoung-Hyun;Kim, Ki-Il;Kim, Sang-Ha
    • Proceedings of the Korea Information Processing Society Conference
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    • 2001.04a
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    • pp.487-490
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    • 2001
  • Mobile IP는 HA(Home Agent)와 FA(Foreign Agent)간의 터널링을 이용하여 IP망에서 단말기의 이동성을 지원하는 표준 프로토콜이다. 하지만 이러한 터널링 방법은 현재 제안되고 있는 인터넷 서비스 연구 즉 통합 서비스(Integrated Service) 및 차별화 서비스(Differentiated Service) 등을 적용하기 위해서는 많은 문제점을 가진다. 대표적인 문제점은 통신망에서는 전송되는 IP 패킷의 헤더에 의해서 세션을 구별하게 되는데 터널링 패킷의 경우 실제 세션과 다른 헤더를 사용하므로 망에서 세션에 대한 처리를 하기 위해서는 내재된 패킷의 정보가 터널링 패킷의 헤더에 반영되어야 한다. 본 논문은 이러한 문제점을 도메인 게이트웨이 라우터에 HA/FA 기능을 추가하는 동시에 RSVP(Resource Reservation Protocol) 플로우를 군집하는 도메인 레벨 QoS(Quality of Service)와 이동성 지원 프로토콜에 QoS를 의존하는 마이크로 레벨 QoS를 분리하는 이단계 구조를 통해 단-대-단 QoS를 보장할 수 있는 방안을 제안한다.

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Conformation of Antifungal Agent Fluconazole

  • Han, Seong Jun;Kang Kee Long;Lee Sung Hee;Chung Uoo Tae;Kang Young Kee
    • Bulletin of the Korean Chemical Society
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    • v.14 no.2
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    • pp.262-265
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    • 1993
  • Conformational free energy calculations using an empirical potential function and a hydration shell model (program CONBIO) were carried out on antifungal agent fluconazole in the unhydrated and hydrated states. The initial geometry of fluconazole was obtained from two minimized fragments of it using a molecular mechanics MMPMI and followed by minimizing with a semiempirical AM1 method. In both states, the feasible conformations were obtained from the calculations of conformational energy, conformational entropy, and hydration free energy by varying all the torsion angles of the molecule. The intramolecular hydrogen bonds of isopropyl hydroxyl hydrogen and triazole nitrogens and the structural flexibility are of significant importance in stabilizing the conformations of fluconazole in both states. Hydration is proved to be one of the essential factors in stabilizing the overall conformation in aqueous solution. Two F atoms of phenyl ring are not identified as an essential key in determining the stable conformations and may be responsible for the interaction with the receptor of fluconazole.

Fiscal Policy and Redistribution in a Small Open Economy with Aging Population

  • Jung, Yongseung
    • East Asian Economic Review
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    • v.25 no.4
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    • pp.361-401
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    • 2021
  • This paper sets up a two agent small open economy with monopolistically competitive firms and catching up with the Joneses to investigate the labor and capital Laffer curve, taking into account aging population along the line of Auray et al. (2016), Galí and Monacelli (2005), and Trabandt and Uhlig (2011). The paper finds that the higher the market power of firms is, the larger the consumption inequality between asset holders and non-asset holders is in the economy with aging population. It also finds that there is room for government to increase the tax revenue by raising tax rates under the economy with higher markup, as households will work more hours to compensate for their loss of labor income to tax hikes. The expected maximum tax revenue is likely to shrink with progressive taxations, since non-asset holders with additional dividend income work less and consume more. The paper finds that the fiscal multiplier decreases with the degree of progressive redistribution.

A Performance Evaluation of Mobile Agent for Network Management (네트워크 관리를 위한 이동 에이전트의 성능평가)

  • 권혁찬;김흥환;유관종
    • The KIPS Transactions:PartC
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    • v.8C no.1
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    • pp.68-74
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    • 2001
  • This paper mentions a centralized approach based on SNMP protocol and distributed approach based on mobile agent in network management s system. And it presents a few Quantitative models for systematically evaluating those two different approaches. To do this, we propose model m that is applicable under a uniform network environment, and compare network execution times of each paradigms based on parameters from s simulation. The model is then refined to take into account non-uniform networks. We show that it can reduce overall network execution times b by determining the best interaction patterns to perfo$\pi$n network management operations from this model. We believe that the model proposed h here should help us to decide appropriate paradigms and interaction patterns for developing network management applications.

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Characterization of Antibacterial activity and Synthesis of Sulfanilamide Polymer using Crosslinking Agent (가교제를 이용한 Sulfanilamide 중합체의 합성과 항균특성)

  • Kim, Jong-Woan;Yoon, Chul-Hun;Hwang, Sung-Kwy;Kong, Seung-Dae;Lee, Han-Seab
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.1
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    • pp.37-42
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    • 2000
  • Drug delivery system(DDS) have been actively studied for the past twenty years. Dual action agents are unique chemical entities comprised of two different types of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. In spite of the advent of the antibacterial agent the sulfa agents are the most widely used antibacterial agent today. In this study, new antibacterials derivative was synthesized using glutaraldehyde such as crosslinking agent for the purpose of dual-action as DDS study. Antibacterial activity of these new synthetic derivative between their structures and activities were examined by disc diffusion method. As a result, new synthetic derivative exhibited the broad antibacterial activities against Gram(+) and Gram(-) bacilli. Especially, the antibacterial effect of new synthetic derivative against Gram negative(Esherichia. coli) was much stronger than that against Gram positive.