• Genomics & Informatics
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• v.12 no.4
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• pp.145-150
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• 2014

Recent technical advances, such as chromatin immunoprecipitation combined with DNA microarrays (ChIp-chip) and chromatin immunoprecipitation-sequencing (ChIP-seq), have generated large quantities of high-throughput data. Considering that epigenomic datasets are arranged over chromosomes, their analysis must account for spatial or temporal characteristics. In that sense, simple clustering or classification methodologies are inadequate for the analysis of multi-track ChIP-chip or ChIP-seq data. Approaches that are based on hidden Markov models (HMMs) can integrate dependencies between directly adjacent measurements in the genome. Here, we review three HMM-based studies that have contributed to epigenetic research, from a computational perspective. We also give a brief tutorial on HMM modelling-targeted at bioinformaticians who are new to the field.

• International Journal of Naval Architecture and Ocean Engineering
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• v.8 no.4
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• pp.320-329
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• 2016

An implicit method of solving the six degree-of-freedom rigid body motion equations based on the second order Adams-Bashforth-Moulten method was utilised as an improvement over the leapfrog scheme by making modifications to the rigid body motion solver libraries directly. The implementation will depend on predictor-corrector steps still residing within the hybrid Pressure Implicit with Splitting of Operators - Semi-Implicit Method for Pressure Linked Equations (PIMPLE) outer corrector loops to ensure strong coupling between fluid and motion. Aitken's under-relaxation is also introduced in this study to optimise the convergence rate and stability of the coupled solver. The resulting coupled solver ran on a free floating object tutorial test case when converged matches the original solver. It further allows a varying 70%-80% reduction in simulation times compared using a fixed under-relaxation to achieve the required stability.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.7
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• pp.515-526
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• 2003

Tutorial contents of kinematics and dynamics of a wheeled drive mobile robot are presented. Based on the dynamic model, simulation studies of position tracking of a mobile robot are performed. The control structure of several position control algorithms using visual feedback are proposed and their performances are compared. In order to compensate for uncertainties from unknown dynamics and ignored dynamic effects such as slip conditions, neural network based position control schemes are proposed. Experiments are conducted and the results show the performance of the vision based neural network control scheme fumed out to be the best among several proposed schemes.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.36
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• pp.371-377
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• 1995

Modern combat (or commertial) aircraft systems consist of a large number of sophisticated and complex avionics/electronics subsystems. The US Air Force of Productivity, Reliability, Availability and Maintainability (PRAM) reports that 25 to 45 percent of aircraft system failures in the electronics or electromechanical area 〔Kachmar, 1985〕. It is an important issue to achive the required reliability and maintainability for avionics/electronics subsystems in order to guarantee the mission success during the life cycle in a timely and cost effective manner. The issuance of USAF Mil-A-87244, "Avionics/Electronic Integrity Program requirements," 1987 demands a new approach called "Avionics/Electronics Integrity Program" (AVIP). The objective of this paper is to give a tutorial presentation on the basic aspects of Avionics/Electronics Integrity efforts in relation to total quality management of avionics/electronics whose performance measures are expressed in terms of reliability, durability, and matainability.

• Journal of Broadcast Engineering
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• v.6 no.3
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• pp.270-282
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• 2001

This paper Introduces three well-known blind watermarking algorithms in terms of signal processing aspects. Those three methods include correlation-based, echo-hiding, and patchwork algorithms. Those algorithms can be applied either in time-domain (or equivalently spatial-domain) or frequency-domain (or equivalently transform-domain). This paper describes watermark embedding and detection algorithms as well as basic ideas for those watermarking algorithms. In addition, we include some experimental results.

• Korean Institute of Interior Design Journal
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• no.18
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• pp.16-22
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• 1999

The purpose of this study is to analyze the drafting process by using AutoCAD for the basic course as well as to suggest the educational basic data of CAD in interior desigv. This research is to show not only practical use of CAD as a drafting tool function, but offering optimizing ways of AutoCAD command usage. The method used for this study is based on an analyzing of 6 types of total 98 types AutoCAD tutorial manual in CAD section of Kyobo book center. After the analysis of the AutoCAD command usage in creating floor plan, characteristics of drafting process is nearly the same as traditional drafting process. It means that traditional drafting process grafted on to computer aided drafting process. And the practical usage of AutoCAD command type is Draw, Modify, Format and View command in creating floor plav. That is emphasis on a specific functiov. Therefore, it should be developed basic course program which adapted various function of AutoCAD.

• Journal of Integrative Natural Science
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• v.5 no.3
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• pp.195-197
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• 2012

Halogen atoms in a molecule are traditionally considered as electron donors, since they have unshared electrons. Normally when they are bonded, there are three lone pair electrons. These lone pairs can function as Lewis bases. However, when they are bound to electron withdrawing groups, they can act as Lewis acids. Since the situation is similar hydrogen bonding (HB), this type of interaction is named as halogen bonding (XB). This mainly comes from the uneven distribution of electron density around the halogen atoms. Since the electron density around halogen atom opposite to ${\sigma}$-bond is depleted, its electropositive region is called ${\sigma}$-hole. This ${\sigma}$-hole can attract halogen bond acceptors, requiring more stringent directionality compared to HB. Since this interaction mainly comes from electrostatic origin, the geometry tends to be linear. Since the XB energy is comparable to corresponding HB. Still in its infancy, XB shows a broad range of applicability, with potentially more useful properties, compared to corresponding HB.

• IEMEK Journal of Embedded Systems and Applications
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• v.16 no.6
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• pp.307-312
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• 2021

This paper proposes an adaptive time-delayed control approach with the integral sliding-mode surface for the fast convergence rate of robot manipulators. Adaptive switching gain aims to guarantee the system stability in such a way as to suppress time-delayed estimation error in the proposed control approach. Moreover, it makes an effort to increase the convergence ability in reaching the phase. An integral sliding-mode surface is employed to achieve a fast convergence rate in the sliding phase. The stability of the proposed one is proved to be asymptotically stable in the Lyapunov stability. The efficiency of the proposed control approach is illustrated with a tutorial example in robot manipulator, which is compared to that of the existing control approach.

• Translational and Clinical Pharmacology
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• v.26 no.4
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• pp.150-154
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• 2018

This tutorial reviews the principles of dose individualisation with an emphasis on target concentration intervention (TCI). Once a target effect is chosen then pharmacodynamics can predict the target concentration and pharmacokinetics can predict the target dose to achieve the required response. Dose individualisation can be considered at three levels: population, group and individual. Population dosing, also known as fixed dosing or "one size fits all" is often used but is poor clinical pharmacology; group dosing uses patient features such as weight, organ function and comedication to adjust the dose for a typical patient; individual dosing uses observations of patient response to inform about pharmacokinetic and pharmacodynamics in the individual and use these individual differences to individualise dose.

• International Journal of Contents
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• v.15 no.2
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• pp.13-19
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• 2019

This research demonstrates a clear visual outline of character influence-relations in creating Jungian character archetypes in films using R computational technology. It contributes to the integration of Jungian analytical psychology into film studies by revealing character network relations in film. This paper handles character archetypes and their influence on developing other character archetypes in films in regards to network analysis drawn from Lynn Schmidt's analysis of 45 master characters in films. Additionally, this paper conducts a character network analysis visualization experiment using R open-source software to create an easily reproducible tutorial for scholars in humanities. This research is a pioneering work that could trigger the academic communities in humanities to actively adopt data science in their research and education.