• Korean Journal of Veterinary Service
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• v.47 no.3
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• pp.173-178
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• 2024

In this case study, we present a rare occurrence of simultaneous primary malignant neoplasms arising from the mammary gland and uterus in conjunction with pyometra and inguinal hernia. The subject, a 16-year-old intact mixed-breed dog, exhibited tubulopapillary carcinoma of the mammary gland with grade II malignancy and uterine leiomyosarcoma. Treatment involved partial mastectomy for the mammary carcinoma and ovariohysterectomy for the uterine leiomyosarcoma. Moreover, the inguinal hernia was concurrently repaired during the tumorectomies. The patient demonstrated positive postoperative progress over a span of two years, emphasizing the effectiveness of surgical intervention in managing the coinciding pathologies in an elderly canine. This unique co-occurrence of primary malignant neoplasms originating from distinct organ systems presents valuable insights into diagnostic approaches, disease characteristics, and surgical interventions in the realm of clinical oncology.

• Korean Journal of Veterinary Service
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• v.36 no.2
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• pp.127-132
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• 2013

An 11-year-old poodle bitch was presented for investigation of multicentric mammary masses. Abdominal sonography and radiography demonstrated abnormal enlargement of uterus and ovaries. Blood analysis revealed high progesterone concentration. The ovariohysterectomy and mastectomy were performed. Histopathologically, the mammary masses revealed complex carcinoma-tubulopapillary carcinoma with papillary pattern and tubule pattern. In the uterus, cystic endometrial hyperplasia was observed. Scattered inflammatory cells were observed in the endometrial stroma and mucinous material was protruded from endometrial surface. Also, in the ovaries, bilateral ovary granulosa cell tumor was detected. The bitch made a complete recovery following the ovariohysterectomy and mastectomy. This case was a very rare multiple tumor occurrence with bilateral ovary granulosa cell tumor and mammary complex carcinoma. High progesterone concentration was characterized clinically in the bitch.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2003.10a
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• pp.48-48
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• 2003

Mammary cancer is the most common malignant neoplasm in the bitch. It constitute 40 percent of all tumors in female dogs, which is three times higher than incidence of mammary tumors in humans[2]. Cytological differentiation between benign and malignant canine mammary tumors is difficult, however, an irregular chromatin pattern was reported to be a significant criterion for malignancy[1]. It can be estimated that approximately 30 percent of the surgically removed mammary tumors are malignant[4]. Malignant mammary tumors often have some degree of infiltrative/destructive growth into adjacent tissues and/or invasion of vessels. Malignant mammary tumors often metastasize into local lymph nodes and lungs, and less frequently into other organs[3]. Based on histological and cytological criteria, this case was diagnosed as tubulopapillary carcinoma of the mammary gland. (omitted)