• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권4호
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• pp.239-245
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• 2012

Purpose: Vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis and lymphangiogenesis including induction of endothelial cell proliferation, migration and capillary tube formation. E7080 (S1164, Selleck chemical, Houston, TX, USA) is a muti-targeted kinase inhibitor, which targets VEGF receptor-2, 3 (VEGFR-2, 3) and inhibits survival and proliferation of tumor cell. The purpose of this study was to determine the anti-tumor effect of E7080 on oral squamous cell carcinoma. Methods: An oral squamous cell carcinoma cell line, SCC-9 was used in this study. E7080 was applied to SCC-9 cells by 3 different concentrations (1, 5, 10 ${\mu}g/mL$). Control means no application of E7080. The cellular growth was evaluated by real-time cell electronic sensing and MTT assay. The signal transduction was evaluated by Western blotting. Results: In experimental group, SCC-9 cell proliferation was decreased and the VEGFR-3 downstream pathways were inhibited compared with control. Furthermore, increasing the concentration of E7080, the ability of E7080 to disturbance of SCC-9 cell proliferation was increased. Conclusion: Proliferation of SCC-9 cells was inhibited by E7080, which was through by inhibition of VEGFR-3 downstream pathway. In vivo study with E7080 will be required to provide therapeutic benefits in oral squamous cell carcinoma.

• Composites Research
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• 제25권6호
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• pp.178-185
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• 2012

본 연구에서는 기능성 나노복합재를 제작하는 방법이 제시되었다. 미소 입자들을 포함하고 있는 점성을 가진 유체에 전기장을 가하여 유체속에 포함된 입자들을 전기장의 방향에 따라 규칙적으로 배열을 하였다. FAiMTa 기술이라고 불리는 이 방법은 마이크로 혹은 나노 사이즈의 입자들을 체인의 형태로 배열하여 직교이방성 폴리머 나노복합재의 제작을 가능하게 하였다. 알루미나($Al_2O_3$), 탄소나노튜브(CNT), 탄소(Graphite), 텅스텐(W) 등의 마이크로 혹은 나노 사이즈 입자 분말을 사용하여 FAiMTa기술의 유효성을 확인하는 시험을 수행하였다. 이러한 입자들을 전기장을 사용하여 일정한 방향으로 배열하여 직교이방성 폴리머 복합재를 만들었고, 시험시편의 물리적 특성 즉 기계적 열적 특성을 측정하여 방향성을 확인하였다. 이렇게 제작된 첨단 나노복합재는 각종 산업분야에서 큰 효과가 기대된다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.328-328
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• 2017

Drought is a major limiting factor that reduces rice production and occurs often especially under recent climate change. Plants have the ability to alter their developmental morphology in response to changing environment, which is known as phenotypic plasticity. In our previous studies, we found that one chromosome segment substitution line (CSSL50 derived from Nipponbare and Kasalath crosses) showed no differences in shoot and root growth as compared with the recurrent genotype, Nipponbare under non-stress condition but showed greater growth responses compared with Nipponbare under mild drought stress condition. We hypothesized that reducing root respiration as metabolic cost, which may be largely a consequence of aerenchyma formation would be one of the key mechanisms for root plasticity expression. This study aimed to evaluate the root respiration and aerenchyma formation under various soil moisture conditions among genotypes with different root plasticity. CSSL50 together with Nipponbare and Kasalath were grown under waterlogged conditions (Control) and mild drought stress conditions (20% of soil moisture content) in a plastic pot ($11cm{\times}14cm$, ${\varphi}{\times}H$) and PVC tube ($3cm{\times}30cm$, ${\varphi}{\times}H$). Root respiration rate was measured with infrared gas analyzer (IRGA, GMP343, Vaisala, Finland) with a closed static chamber system. There was no significant difference between genotypes in control for shoot and root growth as well as root respiration rate. In contrast, all the genotypes increased their root respiration rates in response to mild drought stress. However, CSSL50 showed lower root respiration rate than Nipponbare, which was associated by higher root aerenchyma formation that was estimated based on internal gas space (porosity) under mild drought stress conditions. Furthermore, there were significant negative correlations between root length and root respiration rate. These results imply that reducing the metabolic cost (= root respiration rate) is a key mechanism for root plasticity expression, which CSSL50 showed under mild drought.

• 동력기계공학회지
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• 제21권2호
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• pp.64-69
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• 2017

The purpose of this study is to investigate the performance characteristics of seawater cooling system for a fishing vessel. The circulation amount of refrigerant, condensation capacity, evaporation capacity, compression work and coefficient of performance(COP) were analyzed as the heat source temperature changed. The experimental setup consisted of an open-type compressor, a shell&tube type condenser, an evaporator and an expansion valve. The heat source was controlled by a constant temperature chamber. The main results of this study are summarized as follows. The condensation capacity increased with increasing heat source temperature, and it was confirmed that the effect of circulating amount of refrigerant was dominant. The amount of heat for vaporization was almost constant even though the temperature of the heat source increased. On the other hand, the compression power was increased. This is because the compression ratio increases as the condensation pressure, the enthalpy difference between inlet and outlet, the amount of circulating refrigerant increases. The performance coefficient of this system showed a tendency decreasing with increasing heat source temperature. Therefore, the basic data of the seawater cooling system for the maintenance of the catch line of the shore fishing boats was acquired through this study, and it is considered that it will be sufficient for the actual design.

• Parasites, Hosts and Diseases
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• 제55권5호
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• pp.541-548
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• 2017

A survey was performed to know the infection status of echinostome metacercariae in Cipangopaludina chinensis malleata snails from Korea. Total 75 snails collected in 5 localities, i.e., Imsil-gun, Jeollabuk-do, Hwasun-gun and Shinan-gun (Aphae and Jido), Jeollanam-do, and Jinju-si, Gyeongsangnam-do, were examined for metacercariae by the artificial digestion method. Infection rates of metacercariae were 80.0%, 66.7%, 100%, 60.0%, and 73.3%, and their densities were 39, 32, 183, 19, and 30 per snail infected, respectively. The metacercariae were round, $105-118{\times}105-118{\mu}m$ in size, with a thin cyst wall, collar spines on the head collar, and excretory granules in 2 canals of excretory tube. Adult flukes were elongated, ventrally curved, and $5,167{\times}939{\mu}m$ in average size. Head collar distinct, bearing 45 collar spines with 5 end groups on each side. Oral sucker subterminal, pharynx well developed, and esophagus somewhat short. Cirrus sac well developed, with a saccular seminal vesicle, and ventral sucker very large. Ovary elliptical and on the median line of the body. Testes tandem and slightly lobed. Eggs operculated, elliptical, and $90-103{\times}55-60{\mu}m$ in size. By scanning electron microscopy, the head collar was prominent with 45 collar spines resembling horns of younger stags. Scale-like tegumental spines were densely distributed on the body surface between the head collar and ventral sucker. Conclusively, it has been first confirmed that the life cycle of E. macrorchis is indigenously maintained in Korea, and C. chinensis malleata snails are popularly infected with the metacercariae of this echinostome.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2010년도 춘계학술발표대회 초록집
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• pp.43-46
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• 2010

As the nuclear power plant has been constructed continuously for several decades in Korea, the welding technology for components manufacturing and installation has been improved largely. Standardization for weld test and qualification was also established systematically according to the concerned code. The welding for the main components requires the high reliability to keep the constant quality level, which means the repeatability of weld quality. Therefore the weld process qualified by thorough test and evaluation is able to be applied for manufacturing. Narrow gap SAW and GTAW process are usually applied for girth seam welding of pressure vessel like Reactor vessel, steam generator, and etc. For the surface cladding with stainless steel and Inconel material, strip welding process is mainly used. Inside cladding of nozzles is additionally applied with Hot wire GTAW and semi-auto welding process. Especially the weld joint having elliptical weld line on curved surface needs a specialized weld system which is automatically rotating with adjusting position of the head torch. The small sized pipe, tube, and internal parts of reactor vessel requests precise weld processes like an automatic GTAW and electron beam welding. Welding of dissimilar materials including Inconel690 material has high possibility of weld defects like a lack of fusion, various types of crack. To avoid these kinds of problem, optimum weld parameters and sequence should be set up through the many tests. As the life extension of nuclear power plant is general trend, weld technologies having higher reliability is required gradually. More development of specialized welding systems, weld part analysis and evaluation, and life prediction for main components should be taken into a consideration extensively.

• International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
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• 제26권1호
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• pp.43-58
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• 1998

The Kwinana Shoreline Fumigation Experiment (KSFE) took place at Fremantle, WA, Australia between January 23 and February 8, 1995. The CSIRO DAR LIDAR measured plume sections from near the Kwinana Power Station (KPS) stacks to up to about 5 km downstream. It also measured boundary layer aerosols and the structure of the boundary layer on some occasions. Both stages A and C of KPS were used as tracers at different times. The heart of the LIDAR system is a Neodymium-doped Yttrium-aluminum-garnet (Nd:YAG) laser operating at a fundamental wavelength of 1064 nm, with harmonics of 532 nm and 355 nm. For these experiments the third harmonic was used because the UV wavelength at 355 nm is eye safe beyond about 50 m. The laser fires a pulse of light 6 ns in duration (about 1.8 m long) and with an energy (at the third harmonic) of about 70 mJ. This pulse subsequently scattered and absorbed by both air molecules and particles in the atmosphere. A small fraction of the laser beam is scattered back to the LIDAR, collected by a telescope and detected by a photo-multiplier tube. The intensity of the signal as a function of time is a measure of the particle concentration as a function of distance along the line of the laser shot. The smoke plume was clearly identifiable in the scans both before and after fumigation in the thermal internal boundary layer (TIBL). Both power station plumes were detected. Over the 9 days of operation, 1,568 plumes scans (214 series) were performed. Essentially all of these will provide instantaneous plume heights and widths, and there are many periods of continuous operation over several hours when it should be possible to compile hourly average plume statistics as well. The results of four days LIDAR observations of the dispersion of smoke plume in the TIBL at a coastal site are presented for the case of stages A and C.

• 한국식품영양과학회지
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• 제15권4호
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• pp.51-55
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• 1986

본 계량적 분체 낙하봉지는 현재 사용하고 있는 4각형 합성수지제 분체 포장의 구조를 개조하여 최종 용기로써 계량적 사용이 가능 하도록 봉지 몸체에 분체 박하유도 튜브를 연결하고 그 튜브 끝단에 개폐용 핀을 채운 구조이다. 이 계량적 분체 박하봉지는 현재 사용하고 있는 분체 봉지에 비해서 봉지의 개봉이 쉽고, 분획 사용 후 재 밀봉이 긴밀하게 될 수 있으며, 재 밀봉이 철저하게 되므로 흡방지 및 anti-caking효과가 크다. 그리고 먼지나 곤충과 같은 이물질의 혼입이 없으며 계량적 사용으로 경제적이고 환경과 하수의 오염을 최소화 하는 효과가 있다. 또한 개봉후 세워둘 때 넘어져 엎지러져 일어나는 손실이 없는 등의 장점이 있다. 따라서 본계량적 분체 낙하봉지는 분상의 설탕, 소금, MSG와 같은 조미료, coffee 및 세제는 물론 농약의 계량적 사용에 실용성을 줄 것으로 생각된다.

• 한국철도학회논문집
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• 제12권4호
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• pp.457-464
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• 2009

디젤 엔진 매연 필터의 입구부와 배출 가스 배출을 위한 배기관 연결을 직선 또는 곡선으로 형태로 연결하였을 때의 DPF 입구 유속 분포를 $STAR-CD^{(R)}$ 전산해석 프로그램을 사용하여 시뮬레이션하였다. 곡관의 형상을 나타내는 3 종류의 수치해석 용 격자 모델을 사용하여 DPF 입구에서의 유속 분포를 시뮬레이션 하였다. 피토관을 2차원 이송장치에 탑재하고 위치를 이동시키며 측정한 유속 분포와 동일한 조건에서 시뮬레이션한 결과와 비교하였다. DPF 입구와 $90^{\circ}$의 곡관이 연결된 조건에서 CFD 해석을 수행한 결과 입구 단면에서의 유속 분포가 말발굽 형태를 나타내었으며 최대 유속값이 DPF 중심축에서 약간 벗어난 위치에서 나타나고 있다. 이러한 CFD 해석결과는 실험 결과와 비교적 잘 일치하였다.

• Nuclear Engineering and Technology
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• 제27권1호
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• pp.53-66
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• 1995

현재 사용중인 Non-LOCA 해석용 인허가 코드들은 특정한 형태의 가압경수로에 맞게 짜여진 것들이어서 모든 형태의 가압 경수로에 적용할 수 있는 범용 코드의 개발이 필요한 실정이다. 이를 위하여 한국원자력연구소에서는 웨스팅하우스 및 CE형 발전소에 공히 적용할 수 있는 과도현상 해석 코드인 TASS 로드를 개발하고있다. 이 TASS 코드는 실시 간 보다 빠르게 핵증기계통에 대한 모의 계산을 수행하며 대화식의 입출력을 통하여 사용자가 원하는 과도현상을 정확히 모사할 수 있다. 본 논문에서는 웨스팅하우스형 발전소에 대하여 TASS 코드를 적용하여 Non-LOCA 인허가 해석을 하기 위한 검증을 위해, 교류 전원 상실사고와 부하상실사고에 대하여 발전소 실측자료와의 비교계산을 수행하였고 주급수관 파단사고, 펌프축 고착사고, 증기발생기 세관 파열사고 및 주증기관 파단사고들에 대하여 대형코드인 RELAP5 /MOD3 코드와의 비교계산을 수행하였다.