• Archives of Pharmacal Research
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• v.8 no.3
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• pp.133-137
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• 1985

The aglycones of saponins isolated from Melandrium firmum were identified as gypsogenin, gypsogenic acid and quillaic acid.

• Archives of Pharmacal Research
• /
• v.8 no.4
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• pp.221-227
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• 1985

Acetyl-11-ketopomolic acid methyl ester (VI), mp 276-$278^{\circ}$ was synthesized from pomolic acid (III). The mild alkaline treatment of VI induced the opening of ring E on carbone skeleton to yield VII, and then VII was deacetylated to give VIII, mp 82-$84^{\circ}$ Compound VIII was established as 11, 19-diketo-18, 19-secoursolic acid methylester. The E-ring opening was believed to be due to regrograde aidol condensation.