• Parasites, Hosts and Diseases
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• 제47권3호
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• pp.235-241
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• 2009

The aim of this study was to estimate the benefit from repeated examinations in the diagnosis of enterobiasis in nursery school groups, and to test the effectiveness of individual-based risk predictions using different methods. A total of 604 children were examined using double, and 96 using triple, anal swab examinations. The questionnaires for parents, structured observations, and interviews with supervisors were used to identify factors of possible infection risk. In order to model the risk of enterobiasis at individual level, a similarity-based machine learning and prediction software Constud was compared with data mining methods in the Statistica 8 Data Miner software package. Prevalence according to a single examination was 22.5%; the increase as a result of double examinations was 8.2%. Single swabs resulted in an estimated prevalence of 20.1% among children examined 3 times; double swabs increased this by 10.1%, and triple swabs by 7.3%. Random forest classification, boosting classification trees, and Constud correctly predicted about 2/3 of the results of the second examination. Constud estimated a mean prevalence of 31.5% in groups. Constud was able to yield the highest overall fit of individual-based predictions while boosting classification tree and random forest models were more effective in recognizing Enterobius positive persons. As a rule, the actual prevalence of enterobiasis is higher than indicated by a single examination. We suggest using either the values of the mean increase in prevalence after double examinations compared to single examinations or group estimations deduced from individual-level modelled risk predictions.

• Journal of Ginseng Research
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• 제30권3호
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• pp.132-136
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• 2006

인삼에 있어 다경 및 잠아 발생형태가 원료삼 및 홍삼 품질에 미치는 영향을 구명하고자 지하부 특성 및 품질요인을 조사하였다. 단경개체는 1-3개의 잠아를 갖는 형태이고 2경개체는 2-3개 그리고 3경개체는 3개의 잠아를 갖는 형태이었다. 또한 단경개체는 62.9% 그리고 2경 이상의 다경개체는 37.1%의 분포를 나타냈다. 원료삼의 등급은 단경개체에 비하여 다경개체가 될 수록 저하하였고 단경개체와 다경개체 모두 잠아수가 많은 개체에서 등급이 낮았다. 경수에 따른 홍삼수율은 대체로 30% 내외로 단경이나 다경개체간에 큰 차이가 없었다. 그러나 본삼수율은 다경개체로 갈수록 감소하는 경향이었다. 홍삼 등급은 다경개체에 비해 단경개체가 양호하였으며 다경개체는 양삼과 잡삼이 많았다. 그리고 잠아수가 많을수록 홍삼등급은 저하하였다.

• Journal of Microbiology and Biotechnology
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• 제29권3호
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• pp.373-381
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• 2019

Site-directed mutagenesis was employed to generate five different triple point mutations in the double mutant (C295A/I86A) of Thermoanaerobacter ethanolicus alcohol dehydrogenase (TeSADH) by computer-aided modeling with the aim of widening the small alkyl-binding pocket. TeSADH engineering enables the enzyme to accept sterically hindered substrates that could not be accepted by the wild-type enzyme. The underline in the mutations highlights the additional point mutation on the double mutant TeSADH introduced in this work. The catalytic efficiency ($k_{cat}/K_M$) of the ${\underline{M151A}}$/C295A/I86A triple TeSADH mutant for acetophenone increased about 4.8-fold higher than that of the double mutant. A 2.4-fold increase in conversion of 3'-methylacetophenone to (R)-1-(3-methylphenyl)-ethanol with a yield of 87% was obtained by using ${\underline{V115A}}$/C295A/I86A mutant in asymmetric reduction. The ${\underline{A85G}}$/C295A/I86A mutant also produced (R)-1-(3-methylphenyl)-ethanol (1.7-fold) from 3'-methylacetophenone and (R)-1-(3-methoxyphenyl)-ethanol (1.2-fold) from 3'-methoxyacetophenone, with improved yield. In terms of thermal stability, the ${\underline{M151A}}$/C295A/I86A and ${\underline{V115A}}$/C295A/I86A mutants significantly increased ${\Delta}T_{1/2}$ by $+6.8^{\circ}C$ and $+2.4^{\circ}C$, respectively, with thermal deactivation constant ($k_d$) close to the wild-type enzyme. The ${\underline{M151A}}$/C295A/I86A mutant reacts optimally at $70^{\circ}C$ with almost 4 times more residual activity than the wild type. Considering broad substrate tolerance and thermal stability together, it would be promising to produce (R)-1-(3-methylphenyl)-ethanol from 3'-methylacetophenone by ${\underline{V115A}}$/C295A/I86A, and (R)-1-phenylethanol from acetophenone by ${\underline{M151A}}$/C295A/I86A mutant, in large-scale bioreduction processes.

• Journal of Contemporary Eastern Asia
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• 제16권1호
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• pp.48-68
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• 2017

Manual elections processes in Egypt have several negative effects; that mainly leads to political corruption due to the lack of transparency. These issues negatively influence citizen's participation in the political life; while electronic voting systems aim to increase efficiency, transparency, and reduce the cost comparing to the manual voting. The main research objectives are, finding the successful factors that positively affects E-voting implementation in Egypt, in addition of finding out the reasons that keep Egyptian government far from applying E-voting, and to come up with the road map that Egyptian government has to take into consideration to successfully implement E-voting systems. The findings of the study suggest that there are seven independent variables affecting e-voting implementation which are; leadership, government willingness, legal framework, technical quality, awareness, citizen's trust in government and IT literacy. Technology-Organization-Environment (TOE) theory was used to provide an analytical framework for the study. A quantitative approach (i.e., survey questionnaire) strategy was used to collect data. A random sampling method was used to select the participants for the survey, whom are targeted voters in Egypt and have access to the internet, since the questionnaire was distributed online and the data is analyzed using regression analysis. Practical implications of this study will lead for more citizen participation in the political life due to the transparency that E-voting system will create, in addition to reduce the political corruption.

• 한국연초학회지
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• 제33권1호
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• pp.21-27
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• 2011

Amadori compounds(1-deoxy-1-amino-2-ketoses) are important precursors of color, flavor and aroma produced in foods. Amadori compounds occur naturally in tobacco. The contribution of amadori compounds to smoke quality has been (of) interest because of their roles of the Maillard reaction in the leaf chemistry. The amounts of these compound in tobacco are affected by the processes of aging, drying and storage conditions. In this study, eight compounds were chemically synthesized because amadori compounds (have not been sold commercially these days.) were not available for obtaining commercially. The aim of this study was to develop the analytical method of amadori compounds in tobacco leaf by the liquid chromatography mass spectrometry using triple quadrupole analyzer(LC-MS/MS). This method was simple, rapid, selective and sensitive, and eight amadori compounds were simultaneously and quantitatively analyzed within 20 minutes. This method showed excellent accuracy and precision. Recovery rates of amadori compounds ranged from 86% to 102%, with relative standard deviation(RSD) ranged from 2.6% to 5.9%. This method was applied to analysis of amadori compounds contents of tobacco leaves in different varieties. Furthermore, it was expected that the method could be extended to the analysis of other amadori compounds.

• 한국해양공학회지
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• 제25권4호
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• pp.54-58
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• 2011

The need and importance of developing and utilizing the oceans, not only as sources of renewable energy and mineral resources, but also as countermeasures to global warming such as for CCS (carbon capture and storage), have continued to increase, especially in countries with limited land areas and resources. Therefore, it is necessary to assess the sustainability of an ocean utilization technology or system not only from an economic point of view but also from an ecological one. For this purpose, it might be effective to develop a comprehensive evaluation method and/or index, by which the assessment of and decisions about a technology and system can be made more objectively. It would also be useful to have an environmental simulation model, which was developed and reported in a previous research. The aim of this study was to modify a reasonable and quantitative index, with which a comprehensive evaluation system can be established, to assess environmental sustainability and risk.

• 대한한의학회지
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• 제41권1호
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• pp.45-54
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• 2020

Objectives: The aim of this study was to investigate relationships between Ryodoraku and carbon monoxide concentration during expiration of smokers. This study was designed as an exploratory observational study. This study was based on the hypothesis that increased levels of carbon monoxide in the smoker's breath may affect indicators that reflect the respiratory and circulatory systems in the Ryodoraku test. Methods: The participants were 49 people who smoked for over a year. They were examined at least one hour after their last smoking. They were tested in a stable state. When examining carbon monoxide during expiration, they breathed deeply, kept breathing for 20 seconds, and slowly exhaled. The Ryodoraku test was performed on its representative points of twelve meridians. Pearson's correlation analysis was used to investigate correlation between the concentration of carbon monoxide in the breath and the current in the measurement points. Results: The higher the carbon monoxide concentration in the exhalation, the significantly greater the current value of Lt H1·both H2·Lt H3·Rt H5, deviation of Lt H1·Lt H2·Lt H3 current value and the laterality between right and left current of H3. Conclusion: The more cigarette smoked, the more changes in heart, lung, pericardium and triple energizer meridians were observed in the Ryodoraku test. I found that increased carbon monoxide in smokers could affect the results of the Ryodoraku test.

• Journal of Astronomy and Space Sciences
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• 제24권1호
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• pp.31-38
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• 2007

We have investigated the evolutionary status of 85 Peg within the framework of standard evolutionary theory. 85 Peg has been known to be a visual and spectroscopic binary system in the solar neighborhood. In spite of the accurate information of the total mass (${\sim}1.5M_{\odot}$) and the distance (${\sim}12pc$) from the HIPPARCOS parallax, it has been undetermined an individual mass, therefore the evolved status of the system. Moreover, the coupled uncertainties of chemical composition and age, make matters worse in predicting an evolutionary status of the system. Nevertheless, we computed the various possible models for 85 Peg, and then calibrated stellar parameters by adjusting to the recent observational data. Our modelling computation has included recently updated input physics and stellar theory such as opacity, equation of state, and chemical diffusion. Through a statistical assessment, we have derived a confident parameter set as the best solution which minimized $X^{2}$ within the observational error domain. Most of all, we found that 85 Peg is not a binary system but a triple system with an unseen companion 85 Peg $B_{b}\;{\sim}0.16M_{\odot}$. The aim of the present paper is (1) to provide a complete modelling of the stellar system based on the evolutionary theory, and (2) to constrain the physical dimensions such as mass, metallicity and age.

• 한국태양에너지학회 논문집
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• 제31권3호
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• pp.67-72
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• 2011

The aim of this study is to evaluate how much would the building energy consumption be saved by applying DSSC BIPV window which is possible to control the transmittance and express the color in the office building. For this, physical characteristics such as transmittance and reflectance, U-factor of DSSC areanalyzed and an annual energy consumption that is connected to dimming control is calculated when DSSC BIPV window is applied by alternate clear window system. As a result, It is possible to reduce the anannual energy consumption as much as4.1% by just change the clear double window system to DSSC BIPV double window system because the major factor to reduce energy consumption in the office that has much cooling load than other building is SHGC. When the thermal insulation properties of DSSC BIPV window with low-e coating and making triple window are improved, energy saving ratio is about 9%. Plus, energy saving ratio of 25~28% in lighting energy consumption is possible when the dimming control system with DSSC BIPV window is adopt.

• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.171-178
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• 2007

Objective : The aim of this study was to evaluate Yangdorak and D.I.T.I. for analysis of Symptom-complexes. Method : This study was selected 26 acne patients in Dongshin University Oriental Medical Hospital. We used Yangdorak (SME5800N, Sord Medicom Co., Korea) and D.I.T.I. (Digital Infrared Thermal Imaging 256, Dorex Inc, Orange CA, USA) and investigated the results of Yangdorak and D.I.T.I.. We made a comparison according to Deficiency or Excess(虛實) of acne patients. Result : In comparing Yangdorak results according to Deficiency or Excess(虛實) of acne patients, Triple-energizer(三焦), Intestine(大腸), Liver(肝), Stomach(胃) meridian in Excess group are higher than Deficiency group, and Kidney(腎) meridian in Deficiency group are lower than Excess group. D.I.T.I. reveald hyperthemia of face and chest on acne patients. The temperature of face and chest on Excess group is higher than Deficiency group. There is no statistically significant value compared with data of other group.