• The Korean Journal of Pain
• /
• v.6 no.2
• /
• pp.192-198
• /
• 1993

In 1984, a magnetic resonance spectrometer(magnetic resonance analyser, MRA $I_{TM}$) was developed by Sigrid Lipsett and Ronald J. Weinstock in the USA, Biomedical applications of the spectrometer have been examined by Dr. Hoang Van Duc(pathologist, USC), and Nakamura, et al(Japan). From their theoretical views, the biophysical functions of this machine are to analyse and synthesize a healthy tissue and organ resonance pattern, and to detect and correct an abnormal tissue and organ resonance pattern. All of the above functions are based on Quantum physics. The healthy tissue and organ resonance patterns are predetermined as standard magnetic resonance patterns by digitizing values based on peak resonance emissions(response levels or high pitched echo-sounds amplified via human body). In clinical practice, a counter or neutralizing resonance pattern calculated by the spectrometer can correct a phase-shifted resonance pattern(response levels or low pitched echo-sounds) of a diseased tissue and organ. By administering the counter resonance pattern into the site of pain and trigger point, it is possible to readjust the phase-shifted resonance pattern and then to alleviate pain through regulation of the neurotransmitter function of the nervous system. For assessing clinical effectiveness of pain relief with MRA $I_{TM}$ this study was designed to estimate pain intensity by the patient's subjective verbal rating scale(VRS such as graded to no pain, mild, moderate and severe) before application of it, to evaluate an amount of pain relief as applied the spectrometer by the patients subjective pain relief scale(visual analogue scale, VAS, 0~100%), and then to observe a continuation of pain relief following its application for managing acute and chronic pain in the 102 patients during an 8 months period beginning March, 1993. An application time of the spectrometer ranged from 15 to 30 minutes daily in each patient at or near the site of pain and trigger point when the patient wanted to be treated. The subjects consisted of 54 males and 48 females, with the age distribution between 23~40 years in 29 cases, 41~60 years in 48 cases and 61~76 years in 25 cases respectively(Table 1). The kinds of diagnosis and the main site of pain, the duration of pain before the application, and the frequency of it's application were recorded on the Table 2, 3 and 4. A distinction between acute and chronic pain was defined according to both of the pain intervals lasting within and over 3 months. The results of application of the spectrometer were noted as follows; In 51 cases of acute pain before the application, the pain intensities were rated mild in 10 cases, moderate in 15 cases and severe in 26 cases. The amounts of pain relief were noted as between 30~50% in 9 cases, 51~70% in 13 cases and 71~95% in 29 cases. The continuation of pain relief appeared between 6~24 hours in two cases, 2~5 days in 10 cases, 6~14 days in 4 cases, 15 days in one case, and completely relived of pain in 34 cases(Table 5~7). In 51 cases of chronic pain before the application, the pain intensities were rated mild in 12 cases, moderate in l8 cases and severe in 21 cases. The amounts of pain relief were noted as between 0~50% in 10 cases, 51~70% in 27 cases and 71~90% in 14 cases. The continuation of pain relief appeared to have no effect in two cases. The level of effective duration was between 6~12 hours in two cases, 2~5 days in 11 cases, 6~14 days in 14 cases, 15~60 days in 9 cases and in 13 cases the patient was completely relieved of pain(Table 5~7). There were no complications in the patients except a mild reddening and tingling sensation of skin while applying the spectrometer. Total amounts of pain relief in all of the subjects were accounted as poor and fair in 19(18.6%) cases, good in 40(39.2%) cases and excellent in 43(42.2%) cases. The clinical effectiveness of MRA $I_{TM}$ showed variable distributions from no improvements to complete relief of pain by the patient's assessment. In conclusion, we suggest that MRA $I_{TM}$ may be successful in immediate and continued pain relief but still requires several treatments for continued relief and may be gradually effective in pain relief while being applied repeatedly.

• Cartoon and Animation Studies
• /
• s.47
• /
• pp.1-29
• /
• 2017

360-degree virtual reality has been a technology that has been available for a long time and has been actively promoted worldwide in recent years due to development of devices such as HMD (Head Mounted Display) and development of hardware for controlling and executing images of virtual reality. The production of the 360 degree VR requires a different mode of production than the traditional video production, and the matters to be considered for the user have begun to appear. Since the virtual reality image is aimed at a platform that requires enthusiasm, presence and interaction, it is necessary to have a suitable cinematography. In VR, users can freely enjoy the world created by the director and have the advantage of being able to concentrate on his interests during playing the image. However, the director had to develope and install the device what the observer could concentrate on the narrative progression and images to be delivered. Among the various methods of transmitting images, the director can use the composition of the short. In this paper, we will study how to effectively apply the technique of directing through the composition of this shot to 360 degrees virtual reality. Currently, there are no killer contents that are still dominant in the world, including inside and outside the country. In this situation, the potential of virtual reality is recognized and various images are produced. So the way of production follows the traditional image production method, and the shot composition is the same. However, in the 360 degree virtual reality, the use of the long take or blocking technique of the conventional third person view point is used as the main production configuration, and the limit of the short configuration is felt. In addition, while the viewer can interactively view the 360-degree screen using the HMD tracking, the configuration of the shot and the connection of the shot are absolutely dependent on the director like the existing cinematography. In this study, I tried to study whether the viewer can freely change the cinematography such as the composition of the shot at a user's desired time using the feature of interaction of the VR image. To do this, 3D animation was created using a game tool called Unreal Engine to construct an interactive image. Using visual scripting of Unreal Engine called blueprint, we create a device that distinguishes the true and false condition of a condition with a trigger node, which makes a variety of shorts. Through this, various direction techniques are developed and related research is expected, and it is expected to help the development of 360 degree VR image.

• Journal of Haehwa Medicine
• /
• v.15 no.1
• /
• pp.125-140
• /
• 2006

Study of east & west medical science documentary records of Hip joint pain lead to following conclusions. 1. Easten medicine classify hip joint pain with terms "Bi-chu-tong", "Bi chu in tong" "Bi-chu-choong-tong". 2. Easten medicine asorts cause of hip joint pain with external factor, such as exogenous energy, six yin evil energy and intrinsic factor, which are weakness caused by prolonged deasease, warm-heat evil. 3. In western medicine, causes that trigger hip joint pain are trauma, fracture, dislocation,and bacterial infection. 4. Treatment of hip joint disorder in western medicine, physiotherapy concerning conservative treatment, and pain control with drug treatment, kinesitherapy are used, and concernig fracture, operation is used. 5. In Eastern medicine, principle of treating hip joint pain, sung-juk-sa-ji(盛則寫之), hu-juk-bo-ji(虛則補之), yul-juk-jil-ji(熱則疾之), han-juk-yu-ji(寒則留之), ham-ha-juk-chim-ji(陷下則沈之), bul-sung-bul-hu(不盛不虛), yi-kyong-chui-ji(以經取之) is presented. This priciple of treatment was descended through ages and is now applied to treatments such as Acupuncture, Herbal, physical treatment based on so-san-eo-hyul(消散瘀血), seo-kun-tong-rak(舒筋通絡), so-ri-kwan-jul(疏利關節) principle. 6. In Eastern medicine, meridians used to treat hip joint pain are The Chok yangmyung wi Kyong(足陽明胃經), Chok taeum bi Kyong(足太陰脾經), Chock soyang dam Kyong(足少陽膽經), Chock guelum gan Kyong(足厥陰肝經). In conclusion, hip joint pain should be considered in relationship with internal organs and whole body system. Western & Eastern point of view should be carefully inspected and connected and intensive study of nervous system and meridian is required, in order to adopt best treatment for the patients.

• The Korean Journal of Zoology
• /
• v.30 no.1
• /
• pp.1-9
• /
• 1987

Cyclic AMP (cAMP) was known to play a key role in the regulation of cumulus expansion and oocyte maturation of mammalian cumulus-oocyte complexes (COC's) in vivo and in vitro. The present experiments were conducted to know how intracellular level of cAMP in these cells is controlled. Intracellular cAMP level was modulated by culturing mouse CGC's with an adenylate cyclase stimulator, forskolin, a phosphodiesterase inhibitor, 3-isobutyl-1-methyixanthine (IBMX), human chorionic gonadotrophin (HCG), or follicle stimulating hormone (FSH). The rate of cumulus expansion and germinal vesicle break-down (GVBD) was checked after culture and used as a biological end point. Forskolin in the medium began to stimulate the expansion of the complexes at 1 nM and induced maximum expansion (80~90%) at 0 1~10 $\mu$M. The expansion rate was reduced to 60% when forskolin concentration was increased to 100 $\mu$M. Oocyte GVBD occurred normally (75~82%) in the presence of 10 $\mu$M of forskolin, but partial suppression was appeared at 100 pM of the drug (40%). IBMX also stimulated the expansion from the concentration of 0.01 pM and induced full expansion (81~89%) between the concentration of 1-1000 $\mu$M. Meiotic resumption was occurred normally under 10 $\mu$M of IBMX, but suppressed drastically from the concentration of 100 $\mu$M. The minimum exposing time to hormone or drugs required to trigger cumulus expansion was two minutes with HCG, 15~30 minutes with FSH and fors kolin, and two hours with IBMX. The data presented here seemed to imply that intracellular cAMP level in cumulus cells is regulated by both adenylate cyclase and phosphodiesterase and cumulus expansion is induced by a peak of cAMP while meiotic arrest is maintained by continuous presence of cAMP.

• Journal of Korean Physical Therapy Science
• /
• v.6 no.1
• /
• pp.897-903
• /
• 1999

Many out patients of the rehabilitation center complaint a pain caused by suffering of MPS, and it brings many different kind of social and ecinomical problems such as medical expenses and the reduction in work efficiency. Therefore, we conducted a research to present a fast and effective treatment to the MPS patients. this research was conducted from November, 1996 to January 1998 with eighteen outpatients who agreed to be the subjects to our reserach. We applied the electric acupuncture on 28 different trigger point on the patients with mostly muscular-skeletal pain and some tender and radiating pain. After the treatment, VRS, VAS, PRI were used to measure the degree of the pain on the patients third and seventh visits, and following results were found. 1. To apply EAP treatment, we acupunctured 6em-Iong needles on Tps region, then the electrodes of pulse generater pg-306 E.S.T were connected on the top of the needles. the electric acupuncture therapy was conducted for 20 minutes with the intensity of 4hz - 60hz(auto wave). The treated electric intensity was the level at which the patients did not feel discomfort. 2. Thirteen out of the 18 participated patients were in their 30s and 40s(72.2%), showing highest frequency. There were more female than male with the ratio of 1 to 1:2. 3. six out of the participated patients (33.3%) had the pain for less then a week, and the average duration of the pain of the participated patients wear 0.8 years. 4. The pain occured mostly in the upper trapezius by 6 part (21.4%), then in the gluteus medius region by 4 part (14.3%). Many of the patients with the pain in the upper back area accompanied varios kind of the referred pains such as radiculopathy, HIVD and Frozen shoulder. 5. MPS occured more frequently on the right side than left side then left side and it seemed to be due to the frequent use of the right hand. 6. There was almost no difference in the measurement of the intensity of the pain right before and after the EAP treatment. Howerver, there was significant decrease in the numerical values of the VAS, and a little bit of decrease in the numerical values of the PRI after the EAP treatment. 7. Based on the results of this present research, it can be concluded that EAP can be used for the treating the myofascial pain syndrome with promptness and safety in most cases.

• Journal of Korea Water Resources Association
• /
• v.47 no.10
• /
• pp.891-906
• /
• 2014

This study suggests the hedging rule of MIP (Mixed Integer Programing) in counting the risk evaluation criteria of the objective function and constraints in order to provide the optimum operating rule in reservoir system as constraining water shortage as much as possible which may happen in the downstream control point of water supply in the aspect of water system management. The proposed model is applied to the Han-river reservoir system for two testing periods (Case I: Jan. 1993~Dec. 1997, Case II: Jan. 1999~Dec. 2003). The model based on the hedging rule with trigger volume, estimated in this study shows that in Case I, the monthly minimum discharge was $310.6{\times}10^6m^3$ in the single operation, $56.3{\times}10^6m^3$ in the joint operation, and $317.5{\times}10^6m^3$ in the hedging rule and also, in Case II, the monthly minimum discharge was found to be $204.2{\times}10^6m^3$ in the single operation, $111.2{\times}10^6m^3$ in the joint operation, and $243.7{\times}10^6m^3$ in the hedging rule. In conclusion, the hedging rule, proposed in this study can decrease vulnerability while guarantees reliability and resiliency.

• Journal of Acupuncture Research
• /
• v.24 no.4
• /
• pp.143-155
• /
• 2007

Objectives: To observe the effect of acupuncture and nerve block combination treatment on adhesive capsulitis patients. Methods : 59 voluntary patients were randomly assigned to acupuncture treatment group(E group, n=22), nerve block treatment group(W group, n=17) and acupuncture and nerve block combination treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, $TE_{14}$, $GB_{21}$ and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received the same treatment as the W group and after 5minutes of rest, successively received the treatment identical to that of E group. All three groups were instructed to practice groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after 1, 2, 3 and 4week treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM), the patient's treatment satisfaction measured by Visual Analogue Scale(VAS) and Digital Infrared Thermographic Imaging(DITI) were used as assessment tools. The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Adduction and Extension improved significantly(p<0.05). The W group showed significant improvement(p<0.05) on CSA, SPADI, VAS and DITI. As for ROM, Abduction and Extension improved significantly. The EW group showed significant improvement(p<0.05) on CSA, SPADI and VAS. As for ROM, Adduction, Abduction, Extension and Flexion improved significantly. The improvement of CSA, VAS and Abduction ROM in the EW group was significantly(p<0.05) superior compared to the groups treated with single type of treatment. Conclusion : It is suggested that acupuncture and nerve block combination treatment for adhesive capsulitis patients is more effective than the two single treatments. Through further studies, the acupuncture and nerve block combination treatment model may be developed into East-West Collaboration Model in treating adhesive capsulitis.

• International Journal of Oral Biology
• /
• v.35 no.2
• /
• pp.61-67
• /
• 2010

Selenoprotein S (SelS) is widely expressed in diverse tissues where it localizes in the plasma membrane and endoplasmic reticulum. We studied the potential function of SelS in erythrocyte differentiation using K562 cells stably over-expressing SelS wild-type (WT) or one of two SelS point mutants, $U_{188}S$ or $U_{188}C$. We found that in the K562 cells treated with $1\;{\mu}M$ Ara-C, SelS gradually declined over five days of treatment. On day 4, intracellular ROS levels were higher in cells expressing SelS-WT than in those expressing a SelS mutant. Moreover, the cell cycle patterns in cells expressing SelS-WT or $U_{188}C$ were similar to the controls. The expression and activation of SIRT1 were also reduced during K562 differentiation. Cells expressing SelS-WT showed elevated SIRT1 expression and activation (phosphorylation), as well as higher levels of FoxO3a expression. SIRT1 activation was diminished slightly in cells expressing SelS-WT after treatment with the ROS scavenger NAC (12 mM), but not in those expressing a SelS mutant. After four days of Ara-C treatment, SelS-WT-expressing cells showed elevated transcription of $\beta$-globin, $\gamma$-globin, $\varepsilon$-globin, GATA-1 and zfpm-1, whereas cells expressing a SelS mutant did not. These results suggest that the suppression of SelS acts as a trigger for proerythrocyte differentiation via the ROS-mediated downregulation of SIRT1.

• Proceedings of the KSPS conference
• /
• 1996.10a
• /
• pp.109-116
• /
• 1996

In this paper, I would like to explore the possibility that the nature of place assimilation can be captured in terms of the OCP within the Optimality Theory (Mccarthy & Prince 1999. 1995; Prince & Smolensky 1993). In derivational models, each assimilatory process would be expressed through a different autosegmental rule. However, what any such model misses is a clear generalization that all of those processes have the effect of avoiding a configuration in which two consonantal place nodes are adjacent across a syllable boundary, as illustrated in (1):(equation omitted) In a derivational model, it is a coincidence that across languages there are changes that have the result of modifying a structure of the form (1a) into the other structure that does not have adjacent consonantal place nodes (1b). OT allows us to express this effect through a constraint given in (2) that forbids adjacent place nodes: (2) OCP(PL): Adjacent place nodes are prohibited. At this point, then, a question arises as to how consonantal and vocalic place nodes are formally distinguished in the output for the purpose of applying the OCP(PL). Besides, the OCP(PL) would affect equally complex onsets and codas as well as coda-onset clusters in languages that have them such as English. To remedy this problem, following Mccarthy (1994), I assume that the canonical markedness constraint is a prohibition defined over no more than two segments, $\alpha$ and $\beta$: that is, $^{*}\{{\alpha, {\;}{\beta{\}$ with appropriate conditions imposed on $\alpha$ and $\beta$. I propose the OCP(PL) again in the following format (3) OCP(PL) (table omitted) $\alpha$ and $\beta$ are the target and the trigger of place assimilation, respectively. The '*' is a reminder that, in this format, constraints specify negative targets or prohibited configurations. Any structure matching the specifications is in violation of this constraint. Now, in correspondence terms, the meaning of the OCP(PL) is this: the constraint is violated if a consonantal place $\alpha$ is immediately followed by a consonantal place $\bebt$ in surface. One advantage of this format is that the OCP(PL) would also be invoked in dealing with place assimilation within complex coda (e.g., sink [si(equation omitted)k]): we can make the constraint scan the consonantal clusters only, excluding any intervening vowels. Finally, the onset clusters typically do not undergo place assimilation. I propose that the onsets be protected by certain constraint which ensures that the coda, not the onset loses the place feature.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.10
• /
• pp.6905-6916
• /
• 2015

The primary purpose of this paper is to find out the environmental regulation in our global society with complex system concept. After the industrial revolution, there were working toward solving various problems while there has been an industry advancement. But, there are various issues that a simple international trade or economic technologic levels were not solved. The evolution of technologies through complex systemic thought are not accidental issues. These issues build and provide a predictable technology innovation that system was emergent a new order. With complex systemic thought, the earth that was facing environmental problems was in the phrase edge of chose. These conditions played the trigger role for the solving various problems in environmental regulations but they don't get along well together. There were no causal relationship between structural elements. This paper describes an emergence of new order through these interactions in environmental regulation. These environmental regulations make desperate efforts not only public sectors but also private or/and firms that make an emergence of new order with the critical point reached. Also, we provide the understanding base an environmental regulation with new order for uncertainty.