• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.12 no.2
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• pp.1-14
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• 2017

Objectives: To systematically evaluate the effectiveness and safety of Chuna manual therapy (CMT) for chronic gastritis (CG). Methods: We searched twelve English, Chinese and Korean databases using relevant keywords up to September 2017. All randomized controlled trials (RCTs) of CMT for CG were considered for inclusion. The methodological quality of included RCTs was assessed by the Cochrane risk of bias tool. Results: Seven RCTs with 403 CG patients were included. The meta-analysis of 6 studies showed that CMT had statistically significant effects (p<0.0001) on effective rate for CG compared to conventional medication. Conclusions: This systematic review suggests that CMT seems effective for CG, but limited evidence from risk of bias. For future studies, high-quality RCTs such as sham-controlled studies with standardized interventions are needed to provide sufficient evidence on the effects of CMT for CG.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.12 no.2
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• pp.15-29
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• 2017

Objectives: To systematically review and evaluate the effectiveness of Chuna manual therapy (CMT) on Pediatric Enuresis. Methods: We searched 12 English, Chinese and Korean databases by using relevant search terms up to October 2017. Every randomized controlled trials (RCTs) of CMT for Pediatric Enuresis were considered for inclusion. The methodological quality of RCTs was assessed by the Cochrane risk of bias tool. Results: Eleven RCTs with 1110 participants were included. The meta-analysis of 11 studies revealed that CMT had statistically significant effects for Pediatric Enuresis compared to other medications in terms of effective rate. Safety issues are minor. Conclusions: This systematic review suggests that CMT may have positive effects on Pediatric Enuresis and safe treatment as a non-pharmacological treatment, but evidence is limited. For a better quality review, more and high-quality RCTs with standardized interventions are needed to offer sufficient evidence on the effects of CMT for Pediatric Enuresis.

• YAKHAK HOEJI
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• v.57 no.4
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• pp.265-271
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• 2013

Treatments of vascular disease via modulating the expression of specific proteins by gene transfer have been attempted in various studies over the past few years. Among several methods to deliver genes, adenovirus currently has been used because of a number of positive aspects. In this study, we test adenoviral vector as a potential mediator in the treatment of vascular disease by using freshly isolated vascular tissues not cultured vascular cells. Freshly isolated vascular tissues were directly exposed to adenoviral vector pAd5CMVmcsIRESeGFPpA to check the possibility of GFP expression in different layer of vascular tissues. We found that the GFP expression by using adenoviral vector experiments is mainly focused on the adventitia and failed to detect GFP expression at endothelial layer or vascular smooth muscle layer in vascular tissues. However, we also found that several integrin receptors are robustly expressed in vascular smooth muscle, thus the limited expression of protein in vascular smooth muscle are not likely the lack of integrin receptors. In conclusion, adenovirus could not be a good tool for a specific protein expression in vascular smooth muscle cell. Thus, the application of adenovirus as a tool for gene therapy of vascular smooth muscle cells in clinical therapeutic trial need to be optimized further.

• Journal of the Korea Safety Management & Science
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• v.7 no.2
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• pp.29-39
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• 2005

우리의 식생활 및 주거 환경이 향상됨에 따라 과거에 비해 학생들의 체격이 커지고 체형 또한 점차 서구화 되가는 경향을 보이고 있으나 아직까지도 초${\cdot}$중${\cdot}$고등학교에서는 학생 자신의 체격에 적합하게 조절하여 사용할 수 없는 고정형 의자를 사용하고 있다. 이에 따라 학생들의 신체발육에 지장을 초래 할 수 있으며 특히 요통과 같은 허리에 문제를 일으킬 수 있다. 따라서 본 연구에서는 학생 자신의 체격에 맞게 높낮이를 자유롭게 조절하여 사용할 수 있는 학생용 의자를 개발하였다. 개발된 조절형 의자는 일반적으로 사용하는 학생용 의자의 다리부분에 풀림과 조임이 가능한 금속제 나사형식의 높이조절봉을 도입하여 공구가 필요 없이 손으로 회전시켜 좌판의 높이를 자유롭게 조절하여 사용할 수 있게 설계하였다. 또한 의자 등받이는 전${\cdot}$후${\cdot}$상${\cdot}$하방향으로 이동되게 함으로써 착석 시 좌판의 깊이와 등받이의 높낮이를 동시에 한번의 동작으로 조절 가능하게 하였다. 한편 개발된 조절형 의자는 현재 우리나라에서 채택하여 사용하고 있는 ISO 5970(Standards for tables and chairs for educational institutions)과 비교하여 수용능력에 따른 적합성 여부를 평가하였으며 피실험자 40명을 대상으로 fitting trials를 실시하였다. 평가결과 개발된 조절형 의자는 두가지 평가 기준에 적합하였으며 실용화 가능성을 발견하였다. 향후 이를 각급 학교 및 학원에 보급 활용함으로써 학생들의 이상체형 형성을 억제하여 신체 발육과 안전을 도모할 수 있으며 학습효과 또한 높일 수 있다고 판단된다.

• Food Science and Biotechnology
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• v.17 no.6
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• pp.1261-1264
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• 2008

In the present study, a randomized, double-blind, placebo-controlled trial to determine the effect of conjugated linoleic acid (CLA) supplementation (50:50 ratio of cis-9, trans-11 and trans-10, cis-12 isomers) for 8 weeks on body composition and biochemical parameters in healthy overweight/obese (body mass index, BMI${\geq}23\;kg/m^2$) Korean subjects was performed, Thirty participants (3 males and 27 females) were randomized to receive placebo (2.4 g olive oil/day) or 2.4g/day CLA (mixture containing 36.9% of cis-9, trans-11 and 37.9% of trans-10, cis-12). Eight weeks of CLA supplementation significantly decreased body weight by -0.75kg, BMI by $-0.27\;kg/m^2$, and hip circumference by -1.11 cm. The reduction of body weight was ascribed to the reduction of body fat mass (-0.59 kg) and lean body mass (-0.18 kg), although these changes were not significant. No significant differences in serum lipid profiles, liver function enzyme activities, and protein concentration were observed in either the CLA or placebo groups. These results indicate that short tenn supplementation (8 weeks) with CLA (2.4 g/day) may decrease body weight in Korean overweight/obese subjects.

• The Korea Journal of Herbology
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• v.36 no.4
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• pp.31-39
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• 2021

Objectives : The purpose of this study was to find out the efficacy of ginseng on the skin by comparing the difference effect between only MTS (microneedle therapy system) and the ginseng solution application after MTS treatment. Methods : The present author performed once a week and total 3 times of MTS treatment. The treatment time took about 5~10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, skin toner was applied after MTS and in the experimental group, ginseng extract dissolved toner was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again. Results : In the case of t-zone oil, there was a significant decrease in the test group and in the case of pores and pigmentation, there was a significant decrease in both the test group and the control group, but the degree of significance was greater in the test group. In the case of skin tone, there was an increase, but no significance. Conclusion : The MTS treatment itself showed good effects on t-zone oil, pores, pigmentation, and skin tone. But the effect was much better when the ginseng extract solution was applied to the skin after MTS treatment. This study suggests that ginseng solution increases the efficacy of MTS.

• International Journal of Contents
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• v.17 no.2
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• pp.20-31
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• 2021

This study aimed to pilot test a newly developed bilateral upper limb rehabilitation training program for improving the upper limb function of individuals with chronic stroke using a visual feedback method. The double-group pretest-posttest design pilot study included 10 individuals with chronic stroke (age >50 years). The intervention (four weekly meetings) consisted of five upper limb training protocols (wrist extension; forearm supination and pronation; elbow extension and shoulder flexion; weight-bearing shift; and shoulder, elbow, and wrist complex movements). Upper limb movement function recovery was assessed with the FuglMeyer Assessment of the Upper Extremity, the Wolf Motor Function Test, the Trunk Control Test, the modified Ashworth Scale, and the visual analog scale at baseline, immediately after, and four weeks after the intervention. The Fatigue Severity Scale was also employed. The Fugl-Meyer Assessment of the Upper Extremity and Wolf Motor Function Test showed significant improvement in upper limb motor function. The Trunk Control Test results increased slightly, and the modified Ashworth Scale decreased slightly, without statistical significance. The visual analog scale scores showed a significant decrease and the Fatigue Severity Scale scores were moderate or low. The bilateral upper limb training program using the visual feedback method could result in slight upper limb function improvements in individuals with chronic stroke.

• Physical Therapy Rehabilitation Science
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• v.10 no.2
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• pp.185-196
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• 2021

Objective: Falling is one of main accident to facilitate the physical injuries in order adults. The purpose of the systematic review was to determine the effects of postural balance training whether the recovery of falls in elderly with normal physical function or not throughout summing the selected studies quantitatively. Design: A systematic review Methods: MEDLINE and other four databases were searched up to April 20, 2021 and randomized controlled trials (RCTs) evaluating postural balance approaches on fall risks in elderly. The researched studies excluded the double studies, titles and abstract, and finally full-reported study. The selected RCTs studies were extracted characteristics of the studies and summary of results based on PICOS-SD (population, intervention, comparison, outcomes, and setting- study design) model to synthesize the papers qualitatively. Results: The review involved 22 RCT reports with 4,847 community older adults aged 65 years or over. Nineteen of the selected RCT studies reported dual or multimodal exercises show the beneficial effect for older adults compared to one-type treatment or no intervention. All of selected showed low risk in the selection, attrition, and reporting bias. However, detection bias showed low risk at 75% records of the involved RCTs and performance bias was low risk at only three records. Conclusions: The results of the systematic review propose that a standardized therapeutic approach and the intensity are needed for improving risk of falls in older adults.

• Economic and Environmental Geology
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• v.56 no.1
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• pp.65-73
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• 2023

As one of the most vulnerable countries to floods, there should be an increased necessity for accurate and reliable flood forecasting in Indonesia. Therefore, a new prediction model using a machine learning algorithm is proposed to provide daily flood prediction in Indonesia. Data crawling was conducted to obtain daily rainfall, streamflow, land cover, and flood data from 2008 to 2021. The model was built using a Random Forest (RF) algorithm for classification to predict future floods by inputting three days of rainfall rate, forest ratio, and stream flow. The accuracy, specificity, precision, recall, and F1-score on the test dataset using the RF algorithm are approximately 94.93%, 68.24%, 94.34%, 99.97%, and 97.08%, respectively. Moreover, the AUC (Area Under the Curve) of the ROC (Receiver Operating Characteristics) curve results in 71%. The objective of this research is providing a model that predicts flood events accurately in Indonesian regions 3 months prior the day of flood. As a trial, we used the month of June 2022 and the model predicted the flood events accurately. The result of prediction is then published to the website as a warning system as a form of flood mitigation.

• The Korea Journal of Herbology
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• v.37 no.2
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• pp.23-31
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• 2022

Objectives : The purpose of this research was to find out the efficacy of Castanea crenata Inner Shell (CCIS) on the skin by comparing the difference effect between only MTS (microneedle therapy system) and the CCIS essence application after MTS treatment. Methods : The present author performed once a week and total 3 times of MTS treatment. The treatment time took about 5 ~ 10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, essence base was applied after MTS and in the experimental group, CCIS powder dissolved essence was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again. Results : In the case of the test group and the control group, there was a significant decrease in thermography temperature and there was a significant increase in skin tone. In the case of pores and pigmentation, there was no significant difference on both group. In the case of moisture, there was a significant increase only in the test group. Conclusion : The MTS treatment itself showed good effects on thermography temperature and skin tone. But in the case of the moisture effect, it was much better when the CCIS essence was applied to the skin after MTS treatment. This study suggests that CCIS essence increases the efficacy of MTS on the point of moisture.