• Title/Summary/Keyword: Trial Division

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Effects of Acupuncture on Urinary Incontinence in Premenopausal Women : Preliminary Study (폐경 전 여성 요실금에 대한 침치료 효과 : 예비연구)

  • Yun, Young-Ju;Kang, Kyung-Won;Yang, Ju-No;Chun, Mi-Son;Choi, Jong-Bo;Yang, Jeong-In
    • Journal of Acupuncture Research
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    • v.28 no.3
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    • pp.55-71
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    • 2011
  • Objectives : The purposes of this preliminary study was to examine the feasibility of recruiting women into a clinical trial designed to examine the effects of acupuncture in treating urinary incontinence (UI) in premenopausal women with delivery history and the feasibility of performing the study procedures. We also tried to determine if there was preliminary evidence to suggest that acupuncture may be effective in reducing UI and improving disease-specific quality of life. Methods : This study was a pragmatic randomized clinical trial. Subjects between the ages of 20 and 49 years were randomly assigned to a treatment(n=11) or control group(n=11) and analyzed. Both groups were supposed to do Kegel exercise at home during 4 weeks and acupuncture was applied to the treatment group twice a week(8 sessions) additionally. Subjects performed 1 hour pad test and completed a 3-day urination diary, international consultation on incontinence modular questionnaire(ICIQ), and incontinence - quality of life(I-QOL) at base line and 5 weeks. Results : Both group showed improvement in 1 hour pad test and the reducing amount of UI was significantly larger in treatment group(p=0.0182). The significant improvements in ICIQ and I-QOL were also observed in treatment group and sustained until the follow-up measurement at 16 weeks. Any adverse reaction related to acupuncture did not happen. Conclusions : It was feasible to recruit subjects and perform the study procedures. The positive results of this study support the requirement for additional research investigating the efficacy of acupuncture in the treatment of UI in women.

Effect of Indigenous Herbs on Growth, Blood Metabolites and Carcass Characteristics in the Late Fattening Period of Hanwoo Steers

  • Kim, D.H.;Kim, K.H.;Nam, I.S.;Lee, S.S.;Choi, C.W.;Kim, W.Y.;Kwon, E.G.;Lee, K.Y.;Lee, M.J.;Oh, Y.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.11
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    • pp.1562-1568
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    • 2013
  • This study was conducted to evaluate the effects of indigenous herbal supplements on growth, blood metabolites and carcass characteristics in the late fattening period of Hanwoo steers. In a 6 month feeding trial, thirty Hanwoo steers ($647{\pm}32$ kg) were allotted to one of 5 treatment groups, control (basal diet contained lasalocid), licorice, clove, turmeric and silymarin, with six steers per pen. All groups received ad libitum concentrate and 1 kg rice straw/animal/d throughout the feeding trial. Blood samples were collected at the beginning, middle, and the end of the experiment and the steers were slaughtered at the end. Blood glucose, triglyceride, total protein, and albumin concentrations were higher in the turmeric treatment compared with other treatments. Blood urea nitrogen and creatinine concentrations were highest (p<0.003 and p = 0.071, respectively) in steers treated with silymarin. Alanine aminotransferase activity was lower (p<0.06) for licorice and silymarin compared with the control group. There were no alterations in serum aspartate aminotransferase and gamma glutamyltransferase activities as a consequence of herb treatments (p = 0.203 and 0.135, respectively). Final body weight, body weight gain, average dairy gain and dry matter intake were not significantly different among treatments. Yield grade, marbling score and quality grade were higher for silymarin group than those of the control group (p<0.05). Therefore, the results suggest that silymarin can be used an effective dietary supplement as an alternative to antibiotic feed additive and a productivity enhancer, providing safe and more consumer acceptable alternative to synthetic compounds during the late fattening period of steers.

A Study on the Secure Plan of Clamping Force according to the Variation of Torque-Coefficient in Torque-Shear High Strength Bolts (토크전단형 고력볼트의 토크계수 변동에 따른 체결축력 확보방안에 관한 연구)

  • Lee, Hyeon-Ju;Nah, Hwan-Seon;Choi, Sung-Mo
    • Journal of the Korean Society for Advanced Composite Structures
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    • v.5 no.3
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    • pp.8-16
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    • 2014
  • Torque control method and turn of nut method are specified as clamping method of high strength bolts in the steel construction specifications. Quality control of torque coefficient is essential activity because torque control method, which is presently adopted as clamping method in domestic construction sites, is affected by variation of torque coefficient. The clamping of torque shear bolt is based on KS B 2819. It was misunderstood that the tension force of the TS bolt was induced generally at the break of pin-tail specified. However, the clamping forces on slip critical connections do not often meet the intended tension, as it considerably varies due to torque coefficient dependent on the environmental factors and temperature variables despite the break of the pin tail.This study was focused to evaluate the effect of environmental factors and errors of installing bolts during tightening high strength bolts. The environmental parameters were composed of 'wet' condition, 'rust' condition, 'only exposure to air' condition. And the manufacture of trial product was planned to identify the induced force into the bolts. The algorithm for a trial product was composed of the relation between electricity energy taken from torque shear wrench and tension force from hydraulic tension meter.

Feeding Value of Sugarcane Stalk for Cattle

  • Kawashima, T.;Sumamal, W.;Pholsen, P.;Chaithiang, R.;Boonpakdee, W.;Kurihara, M.;Shibata, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.1
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    • pp.55-60
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    • 2002
  • A metabolism trial with four castrated male Brahman cattle, average body weight 320 kg, was conducted in order to determine the nutritive value of chopped sugarcane stalk (CSS) for the establishment of feeding strategy in the dry season in Northeast Thailand. Animals were subjected to the following four dietary treatments: Treatment 1; 100% of CSS, Treatment 2; 70% of CSS and 30% of commercial complete feed (TMR), Treatment 3; 40% of CSS and 60% of TMR, and Treatment 4; 100% of TMR. The average CP, ether extracts, nitrogen free extracts, crude fiber and ash contents of CSS were 2.0, 0.9, 79.0, 16.1 and 2.2%, respectively. Although the amount of feed given was approximately at maintenance level, animals in treatments 1 and 2 refused a part of feed. The metabolism trial revealed that total digestible nutrient and metabolizable energy contents of CSS were 61.5% and 9.04 MJ/kgDM, respectively, when it was properly supplemented with protein sources. Nutritive value of CSS was lowered when animals were given CSS solely. This was due to the large loss of energy into urine and methane. Voluntary intake of CSS in cattle was not enough to satisfy energy requirement for maintenance. The CSS can be used as a roughage for feeding cattle in the dry season with proper supplementation of protein and energy.

Quality Characteristics of Chiffon Cake Made with Loquat Fruits (Eriobotrya japonica) Powder (비파열매 분말을 첨가한 쉬폰 케이크의 품질 특성)

  • Jung, Su-Young;Bing, Dong-Ju;Chun, Soon-Sil
    • Korean journal of food and cookery science
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    • v.31 no.2
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    • pp.144-152
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    • 2015
  • The loquat (Eriobotrya japonica) is a plant belonging to the Rosaceae family, native to south-central China. It is cultivated in relatively warm areas such as Spain, Japan and South Korea. It is used commercially as an ornamental plant and for its yellow fruit, which contains much carotenoid, sugar and a little organic acid. In this study, chiffon cakes were prepared with the addition of 3%, 6%, 9% and 12% loquat fruit powder (LFP) in order to invest the mixing conditions. When more LFP was added to the dough, the pH level of the dough became lower. Specific gravity and viscosity of the dough significantly increased as higher amounts of LFP were added. In baked cakes, the weight and baking loss rate of LFP were not significantly different between samples, and the height of the risen test samples were lower than that of the controls. Moisture content was 33.58% in the 12% LFP sample (12% LFPS), which was the highest of all the samples. With respect to crust color, lightness, redness and, yellowness, these significantly decreased as the amount of LFP was increased, the 12% LFP being the lowest of all the samples. Lightness and yellowness of crumbs significantly decreased as the amount of LFP was increased, whereas redness showed the reverse effect. When looking at hardness and adhesiveness, the 12% LFPS was the highest of all the samples, nevertheless a difference in resilience was not significant among the samples. According to consumer perception, bitterness was significantly increased as amounts of LFP increased, however a difference in salty, astringency and oily tastes were not significant among the samples. The 12% LFPS showed the lowest score with respect to softness and overall acceptability. In conclusion, LFP could be considered a functional material, with the optimum amount of LFP for a chiffon cake of 3~9%.

Could a Manipulation of Dietary Nutrient Contents Including Phosphorous Affect Compensatory Growth of Juvenile Olive Flounder Paralichthys olivaceus?

  • Cho, Sung Hwoan
    • Fisheries and Aquatic Sciences
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    • v.16 no.1
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    • pp.57-61
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    • 2013
  • I hypothesized that the manipulation of dietary nutrient contents including phosphorous could affect compensatory growth of juvenile olive flounder, Paralichthys olivaceus. Thirty fish averaging 34.8 g per tank were randomly chosen and distributed into 15 flow-through 180-L tanks. Three experimental diets were prepared: the control (C) diet, high protein and lipid (HPL) diet, and HPL diet with supplementation of calcium phosphate-monobasic (HPLP). Five treatments were prepared in triplicate: fish were hand-fed daily with the C diet twice a day for 8 weeks (C-8W); fish were starved for 1 week, and then fed with the HPL or HPLP diets twice a day for 7 weeks, and referred to as HPL-7W and HPLP-7W, respectively; and fish were starved for 2 weeks, and then fed with the HPL or HPLP diets twice a day for 6 weeks, and referred to as HPL-6W and HPLP-6W, respectively. The body weight of fish with C-8W, HPL-7W and HPLP-7W treatments was higher than fish with HPL-6W and HPLP-6W treatments on week 2, 4 and 6 after an initiation of the trial. At the end of the 8-week trial, fish with HPLP-7W and HPL-7W treatments overcompensated, as compared to fish with C-8W treatment. Full compensation was not achieved in fish subjected to the 2-week feed deprivation (HPL-6W and HPLP-6W treatments). Overall feed intake by fish was proportional to weeks of feeding. Feed conversion ratio of fish with HPLP-7W, HPL-6W and HPLP-6W treatments was higher than fish with C-8W treatment. The study showed that dietary supplementation of protein and lipid resulted in overcompensation of juvenile olive flounder subjected to a 1-week feed deprivation, but not a 2-week feed deprivation. Additionally, dietary supplementation of phosphorous did not further improve compensatory growth of fish.

Effects of Aromatherapy on Sleep Quality: A Systematic Review and Meta-Analysis (아로마테라피가 수면에 미치는 효과: 체계적 문헌고찰 및 메타분석)

  • Kim, Mi-Eun;Jun, Ji Hee;Hur, Muyng-Haeng
    • Journal of Korean Academy of Nursing
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    • v.49 no.6
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    • pp.655-676
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    • 2019
  • Purpose: The purpose of this study was to investigate the effects of aromatherapy on sleep quality. Methods: This is a systematic review of randomized controlled trial studies (PROSPERO registration number CRD42017064519). In this study, the PICO were adults and the elderly, aromatherapy intervention, a comparative intervention with the control and placebo oil groups, and sleep. The selected articles were in English, Korean, and Chinese. Results: The results of the meta-analysis showed that the effect sizes of the experimental group were 1.03 (n=763, SMD=1.03, 95% CI 0.66 to 1.39) (Z=5.47, p<.001). In the aromatherapy intervention group, the effect size of sleep was statistically significant (QB=9.39, df=2, p=.009), with a difference of 0.77 for inhalation, 1.12 for oral intake and 2.05 for massage. A post-analysis showed that the effect of massage on sleep was significantly greater than the inhalation method. The regression coefficient of the intervention period, B=0.01 (Z=1.43, p=.154), also showed that the longer the intervention period, the larger the effect size; however, it was not statistically significant. Conclusion: A total of 23 literature analyses showed that aromatherapy is effective in improving quality of sleep, and the massage method is more effective in improving quality of sleep than the inhalation method. A meta-ANOVA showed that the aromatherapy intervention affected the high heterogeneity of the effect size. Thus, future research with stricter control in methods and experimental procedures is necessary.

Effects of Alternate-Week Feeding Strategies on Growth and Feed Efficiency Ratio of Juvenile Nile Tilapia Oreochromis niloticus in a Recirculating System

  • Cho, Sung-Hwoan
    • Fisheries and Aquatic Sciences
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    • v.8 no.3
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    • pp.128-131
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    • 2005
  • The effects of alternate-week feeding strategies on growth and feed efficiency ratio of juvenile Nile tilapia were investigated in a recirculating aquaculture system. Twenty fish initially weighing 25.5 g were randomly distributed into each of 18 tanks to conduct three replicates for each of six different feeding strategies. Weight gain of fish in the control that were fed daily for 6-week feeding trial was significantly higher than those of fish subjected to various alternate-week feeding regimes. Weight gain of fish that were starved for 3 weeks and then fed daily for 3 weeks (3WS+3WF) was not significantly different from that of fish, starved and fed daily for alternate 1-week period during the trial (1WS+1WF), but was significantly higher than those of fish starved for 2 weeks, and fed for 2 weeks (2WS+2WF); fish starved for 4 weeks and fed for 2 weeks (4WS+2WF); and fish fed for 5 weeks and fed for 1 week (5WS+1WF.) The amount of feed supplied to fish in the groups of 1WS+1WF and 3WS+3WF was significantly lower than that fed to fish in the control group, but significantly higher than the amount feed supplied to fish in the other three groups. Feed efficiency ratio for fish in the control group did not differ from that for fish in the groups of 1WS+1WF, 2WS+2WF and 3WS+3WF, but was significantly higher than that for fish in the groups of 4WS+2WF and 5WS+1WF. In conclusion, juvenile Nile tilapia that were subject to starvation for 1 to 5 weeks did not exhibit compensatory growth sufficient to attain the same weight as fish fed daily for 6 weeks. In addition, fish subjected to starvation exhibited low feed efficiency ratio compared to fish fed daily, which were probably attributable to poor weight gain.

Significance of the tethered maxillary frenulum: a questionnaire-based observational cohort study

  • Naimer, Sody A.;Israel, Ariel;Gabbay, Aviezer
    • Clinical and Experimental Pediatrics
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    • v.64 no.3
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    • pp.130-135
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    • 2021
  • Background: The clinical significance of lip-tie, or a tethered maxillary frenulum, remains under debate. Clinicians and parents are often perplexed when deciding whether procedures available to relieve a seemingly tight or severe maxillary frenulum are needed. Purpose: No previous studies have assessed the consequences of not subjecting a tethered maxillary frenulum in newborns to surgical intervention. This study aimed to contribute the first prospective trial on this topic with a relatively extended follow-up of these newborn infants. Methods: This prospective observational questionnaire-based cohort trial was performed in a community setting and aimed to determine whether lip-tie is associated with an increased likelihood of eventual feeding or oral disorders. Results: The convenience sample comprised of 61 consecutively arriving infants with concomitant tethered frenula who were treated at the clinic for various reasons. This cohort was compared with a random sample of 66 age-matched children for a mean follow-up period of 6.42 years. Infants undergoing oropharyngeal procedures were excluded. Awareness of a deviation in oral structures was reported by 18% of the study group versus 0% of the controls. Mothers participating in the study group (24.6%) less frequently recalled painful nipples or discomfort during breastfeeding than those in the control group (47.0%) (P<0.01). There were no intergroup differences in other types of feeding difficulty, dental hygiene, pronunciation, or speech development. Conclusion: Our findings suggest that a tethered labial frenulum is not associated with an increase in breastfeeding disturbances or oral disorders. These data encourage clinicians to question the need to intervene in cases of tethered maxillary frenula.

Clinical Application of Modified Burns Wean Assessment Program Scores at First Spontaneous Breathing Trial in Weaning Patients from Mechanical Ventilation

  • Jeong, Eun Suk;Lee, Kwangha
    • Acute and Critical Care
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    • v.33 no.4
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    • pp.260-268
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    • 2018
  • Background: The purpose of this study was to evaluate the clinical application of modified Burns Wean Assessment Program (m-BWAP) scoring at first spontaneous breathing trial (SBT) as a predictor of successful liberation from mechanical ventilation (MV) in patients with endotracheal intubation. Methods: Patients requiring MV for more than 72 hours and undergoing more than one SBT in a medical intensive care unit (ICU) were prospectively enrolled over a 3-year period. The m-BWAP score at first SBT was obtained by a critical care nursing practitioner. Results: A total of 103 subjects were included in this study. Their median age was 69 years (range, 22 to 87 years) and 72 subjects (69.9%) were male. The median duration from admission to first SBT was 5 days (range, 3 to 26 days), and the rate of final successful liberation from MV was 84.5% (n=87). In the total group of patients, the successful liberation from MV group at first SBT (n=65) had significantly higher m-BWAP scores than did the unsuccessful group (median, 60; range, 43 to 80 vs. median, 53; range, 33 to 70; P<0.001). Also, the area under the m-BWAP curve for predicting successful liberation of MV was 0.748 (95% confidence interval, 0.650 to 0.847), while the cutoff value based on Youden's index was 53 (sensitivity, 76%; specificity, 64%). Conclusions: The present data show that the m-BWAP score represents a good predictor of weaning success in patients with an endotracheal tube in place at first SBT.