• Title/Summary/Keyword: Trend Study

Search Result 12,410, Processing Time 0.041 seconds

Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials (위축성 위염과 장상피화생의 유병률 변화 및 위험인자의 변화: 다기관 연구 비교)

  • Hwang, Young-Jae;Kim, Nayoung;Kim, Sung Eun;Baik, Gwang Ho;Lee, Ju Yup;Park, Kyung Sik;Joo, Young-Eun;Myung, Dae-Seong;Kim, Hyeon Ju;Song, Hyun Joo;Kim, Heung Up;Nam, Kwangwoo;Shin, Jeong Eun;Kim, Hyun Jin;Kim, Gwang Ha;Lee, Jongchan;Lim, Seon Hee;Seo, Geom Seog;Choi, Suck Chei
    • The Korean journal of helicobacter and upper gastrointestinal research
    • /
    • v.18 no.4
    • /
    • pp.247-257
    • /
    • 2018
  • Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016~2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016~2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016~2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016~2017 (51.6%; 1,293/2,506; P<0.001). The prevalence of AG decreased from 2011 to 2016~2017 (P=0.018), but that of IM increased (P<0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016~2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016~2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (${\geq}126mg/dL$), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016~2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.

Characteristics of Indoor Particulate Matter Concentrations by Size at an Apartment House During Dusty-Day (황사 발생시 아파트 실내에서 미세먼지 크기별 농도 특성)

  • Joo, Sang-Woo;Ji, Jun-Ho
    • Particle and aerosol research
    • /
    • v.15 no.1
    • /
    • pp.37-44
    • /
    • 2019
  • It is recommended for the public to stay at home and to close the doors and windows when a high-particulate-matter environment such as a yellow sand event occurs outside. However, there are lack of empirical studies describing how much outdoor PM infiltrates into a closed house and how much indoor PM an inhabitant is exposed to during the period. In this study, the $PM_{10}$ and $PM_{2.5}$ were measured at the kitchen in an apartment house by an optical particle counter for 3 days including a yellow sand event. The outdoor PMs and the outdoor wind speeds were referred from surrounding weather stations. We analyzed the penetration of $PM_{10-2.5}$ and $PM_{2.5}$ at the test house against the outdoor wind speed supposed corresponding to the change of air exchange rate. In addition, the effect of an indoor activity on change in the indoor PM was investigated. In result, the indoor $PM_{10-2.5}$ was very low even a yellow sand event occurred outside; rather, a contribution of indoor activities to increase in $PM_{10-2.5}$ was higher. In contrast, the indoor $PM_{2.5}$ fluctuated following the outdoor $PM_{2.5}$ trend at high wind speeds or remained almost constant at low wind speed.

A study on Sesi Keesokshi in the late Joseon Period -Focusiong on Serial Sesi Keesokshi- (조선후기 세시기속시(歲時記俗詩) 고찰 -대보름 연작형(聯作型) 세시기속시를 중심으로-)

  • Yang, Jin-jo
    • Korean Journal of Heritage: History & Science
    • /
    • v.40
    • /
    • pp.307-323
    • /
    • 2007
  • One of the distinguishing features of late Jeosun s Hanshi (poem in Chinese) is the numerous creation of Yeonjachyung Keesokshi (serial poem on folklore) which describes the folk manner and folk way of life in detail. Keesokshi s subject matter is the folklike in general including local features, geography, climate, local production, humanity, social conducts, and daily labor for living as well. By its material characteristics, Keesokshi reflects detailed life conditions of the society members in each levels, and represents the local customs as well as the folk emotions. Among the several kinds of Keesokshis, a Sesi Keesokshi focuses only in reciting the folk customs on each seasonal festival days, and the great numbers of such serial poems appear during the latter part of the Jeosun Dynasty. Its overall background is the transition of artistic trend which came after many social changes such as expansion of realism, uprising national consciousness, shaken status system, and the rising of 'Jeosun si motives in the Hansi history. Moreover, each writers various experiences and their interests in the reality and critical minds of common people contributed a crucial roll in creation of Sesi Keesokshi. 178 of the 584 remaining serial Sesi Keesokshi are written particularly about the folk customs in The Grand Full Moon Festival (the first full moon of a year by the lunar calendar). These Hanshis widely reflect the common ways of living by directly accepting the seasonal folk customs as the subject matters. Especially, close to the reality, these poems positively express the people's simple vigorous lives and create unrestrained lively image by describing the joys and sorrows of the folk ewistence along with their craving. Also, it is notable to have customs such as 'Shil-Ssa-Um' and 'No-gu-ban-kong-yang' as subjects for its rarity in other literatures.

A study on the detailed treatment techniques of seoktap(stone stupa) in Jeollado province -in the groove for dropping water and the hole for wing bell of the okgaeseok(roof stone)- (전라도 석탑의 세부 기법 고찰 - 옥개석 물끊기홈과 충탁공을 중심으로 -)

  • Cho, Eun-kyung;Han, Joo-sung;Nam, Chang-keun
    • Korean Journal of Heritage: History & Science
    • /
    • v.40
    • /
    • pp.271-306
    • /
    • 2007
  • One of the distinguishing features of late Jeosun's Hanshi (poem in Chinese) is the numerous creation of Yeonjachyung Keesokshi (serial poem on folklore) which describes the folk manner and folk way of life in detail. Keesokshi's subject matter is the folklike in general including local features, geography, climate, local production, humanity, social conducts, and daily labor for living as well. By its material characteristics, Keesokshi reflects detailed life conditions of the society members in each levels, and represents the local customs as well as the folk emotions. Among the several kinds of Keesokshis, a Sesi Keesokshi focuses only in reciting the folk customs on each seasonal festival days, and the great numbers of such serial poems appear during the latter part of the Jeosun Dynasty. Its overall background is the transition of artistic trend which came after many social changes such as expansion of realism, uprising national consciousness, shaken status system, and the rising of 'Jeosunsi' motives in the Hansi history. Moreover, each writer's various experiences and their interests in the reality and critical minds of common people contributed a crucial roll in creation of Sesi Keesokshi. 178 of the 584 remaining serial Sesi Keesokshi are written particularly about the folk customs in The Grand Full Moon Festival (the first full moon of a year by the lunar calendar). These Hanshis widely reflect the common ways of living by directly accepting the seasonal folk customs as the subject matters. Especially, close to the reality, these poems positively express the people's simple vigorous lives and create unrestrained lively image by describing the joys and sorrows of the folk existence along with their craving. Also, it is notable to have customs such as 'Shil-Ssa-Um' and 'No-gu-ban-kong-yang' as subjects for its rarity in other literatures.

Studies on Antioxidant, Anti-inflammatory and Whitening Effects of Oriental Herbal Extracts (Mix) including Eucommiae cortex (두충을 포함하는 한방추출물(Mix)의 항노화, 항염, 미백 효능 활성에 관한 연구)

  • Choi, Da Hee;Kim, Mi Ran;Kim, Min Young;Kim, Ho Hyun;Park, Sun-Young;Hwang, Hyung Seo
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.45 no.1
    • /
    • pp.37-47
    • /
    • 2019
  • Recently, due to the increase in skin diseases caused by particulate matter, endocrine disruptor and environmental changes, the trend of development of cosmetic materials has been shifting to the more safe and effective ingredients based on natural materials rather than existing synthetic compounds like steroids and antihistamines. This study aimed to develop a new natural cosmetic materials using oriental herbs such as Eucommiae cortex, Alpinia oxyphylla Miquel and Bombyx batryticatus. First, DPPH assay was performed to examine the antioxidative activity of the herbal extract (Mix) and 98.8% DPPH radical scavenging activity was confirmed at $400{\mu}g/mL$ concentration of it. In order to confirm the whitening efficacy of oriental herbal extracts(mix), the amount of melanin synthesized after stimulation of ${\alpha}-MSH$ with B16F10 cells was measured. Results showed that it was decreased to 27.1% comparing with the only ${\alpha}-MSH$ treated group, which confirmed the whitening efficacy. Also, both nitric oxide(NO) production and iNOS and COX-2 expression were significantly reduced in RAW264.7 macrophages activated by LPS in the presence of the extracts(Mix). The mRNA expression of the inflammatory cytokines such as $IL-1{\alpha}$, $IL-1{\beta}$, IL-6, and $TNF-{\alpha}$ was also analyzed to confirm the inhibition effect of the extracts on inflammation. Finally, to confirm the enhancement of skin barrier function, the expression of claudin 1 gene, a tight junction protein, was observed using human keratinocyte HaCaT cells and increased as concentration dependent manner. From these results, it is concluded that the oriental herbal extracts(Mix) containing Eucommiae cortex, Alpinia oxyphylla Miquel and Bombyx batryticatus is effective for antioxidant, anti-inflammation, skin whitening, and skin barrier and thus could be applied as a new natural cosmetic material.

Comparison of Domestic and Foreign Design Standards for Overall Stability of Soil Nailed Slopes (쏘일네일 보강 비탈면의 전체 안정성에 대한 국내외 설계기준 비교)

  • Kim, Tae-Won;You, Kwang-Ho
    • Journal of the Korean GEO-environmental Society
    • /
    • v.20 no.6
    • /
    • pp.5-13
    • /
    • 2019
  • The international trend in soil nailed wall design has been evolved from the allowable stress design to limit state design and it is still currently ongoing. The design guidelines in Korea and Hong Kong still adopts the allowable stress design philosophy while those in others mostly do the limit state design. In this study, four soil nail design methods presented in the major design guidelines (U.S. FHWA GEC 7 (2015), Clouterre in France (1991), Soil nailing - best practice guidance in U.K. (CIRIA, 2005), Geoguide 7 in Hong Kong (2008) and Design standard for slope reinforcement work in Korea (KDS 11 70 15 f: 2016)) are described and analyzed in brief. The factor of safety and CDR (Capacity-to-Demand Ratio) which is used to measure the degree of conservatism of a design guide are obtained for the two cases. One is the design example presented in CIRIA (2005) and the other is in-situ loading test performed on the top of backfill of the soil nail wall to investigate the conservatism of design guidelines. It is revealed that the design method in overall stability of soil nail walls in domestic design method (CDR=0.78) is the most conservative and those by Clouterre (CDR=0.99, 1.09), Geoguide 7 (CDR=1.13, 0.97), U.S. FHWA (CDR=1.09, 1.07) and CIRIA (CDR=1.40, 1.16) in order from the second most conservative to the least conservative for the design example presented in CIRIA. For the in-situ loading test performed on the top of backfill of the soil nail wall, the order of conservatism is identical except that the places of Geoguide 7 (CDR=0.66, 0.72) and FHWA (CDR=0.73, 0.72) are changed. However, the results obtained among U.S. FHWA (2015) and Clouterre (1991) and Geoguide 7 (2008) are not so different.

A Study on Containerports Clustering Using Artificial Neural Network(Multilayer Perceptron and Radial Basis Function), Social Network, and Tabu Search Models with Empirical Verification of Clustering Using the Second Stage(Type IV) Cross-Efficiency Matrix Clustering Model (인공신경망모형(다층퍼셉트론, 방사형기저함수), 사회연결망모형, 타부서치모형을 이용한 컨테이너항만의 클러스터링 측정 및 2단계(Type IV) 교차효율성 메트릭스 군집모형을 이용한 실증적 검증에 관한 연구)

  • Park, Ro-Kyung
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
    • /
    • v.9 no.6
    • /
    • pp.757-772
    • /
    • 2019
  • The purpose of this paper is to measure the clustering change and analyze empirical results, and choose the clustering ports for Busan, Incheon, and Gwangyang ports by using Artificial Neural Network, Social Network, and Tabu Search models on 38 Asian container ports over the period 2007-2016. The models consider number of cranes, depth, birth length, and total area as inputs and container throughput as output. Followings are the main empirical results. First, the variables ranking order which affects the clustering according to artificial neural network are TEU, birth length, depth, total area, and number of cranes. Second, social network analysis shows the same clustering in the benevolent and aggressive models. Third, the efficiency of domestic ports are worsened after clustering using social network analysis and tabu search models. Forth, social network and tabu search models can increase the efficiency by 37% compared to that of the general CCR model. Fifth, according to the social network analysis and tabu search models, 3 Korean ports could be clustered with Asian ports like Busan Port(Kobe, Osaka, Port Klang, Tanjung Pelepas, and Manila), Incheon Port(Shahid Rajaee, and Gwangyang), and Gwangyang Port(Aqaba, Port Sulatan Qaboos, Dammam, Khor Fakkan, and Incheon). Korean seaport authority should introduce port improvement plans by using the methods used in this paper.

Understanding the Access and Benefit-Sharing of Genetic Resources for Environmental Ecology Researchers (나고야의정서 이행에 따른 ABS 체계의 이해와 환경생태분야 연구자의 대응방안)

  • Lee, Jonghyun;An, Minho;Chang, YounHyo
    • Korean Journal of Environment and Ecology
    • /
    • v.35 no.4
    • /
    • pp.336-346
    • /
    • 2021
  • The enforcement of the Nagoya Protocol, which regulates the acquisition and use of genetic sources, an essential material for biotechnology R&D, has imposed a burden for additional documentation works to researchers. In the past, countries regarded genetic resources as a common human heritage and thus allowed researchers to use them freely. However, they can no longer afford the luxury of such freedom now since many countries are introducing new laws and regulations on the acquisition and use of the resources as the Nagoya Protocol recognizes the exclusive ownership of genetic resources. Therefore, Korea, which is highly dependent on foreign genetic resources, needs a more systematic response. This paper aims to review the key contents of the Nagoya Protocol to raise awareness among domestic and foreign genetic resource users, including researchers of environment and ecology and present the overall structure, and flow of acquisition, access, and benefit sharing (ABS) for the use of foreign genetic resources to help them respond appropriately to the new landscape. The researchers' efforts and support at the national level are necessary at the same time to appropriately respond to the Nagoya Protocol. First, the researchers must understand the overall framework and the specific response in each stage under the Nagoya Protocol scheme. It is necessary to respond to the ABS procedure of the resource provider country from accessing genetic resources to sharing benefits resulting from it. In that regard, the Nagoya Protocol has imposed more restrictions on research activities and raised the burden outside of research. The current trend of recognizing the country's sovereign rights over genetic resources is likely to continue and widespread worldwide as resource-rich countries are expected to continue protecting their resources. Therefore, our study will help environmental ecology researchers understand ABS and conduct research under the Nagoya Protocol and legal obligations of resource provider countries step by step, from access to benefit sharing.

A Review of Ecological Niche Theory from the Early 1900s to the Present (생태적 지위(Ecological Niche) 이론에 대한 검토 및 제언)

  • Koo, Kyung Ah;Park, Seon-Uk
    • Korean Journal of Environment and Ecology
    • /
    • v.35 no.4
    • /
    • pp.316-335
    • /
    • 2021
  • This study reviewed the change of theory of ecological niche(concepts and definitions) over time to provide a theoretical basis for habitat-related studies of animals and plants. Accordingly, it analyzed and summarized the major discussion trends of ecological niche worldwide in each period from the 1900s to the present. Countries advanced in ecological studies, such as the EU and the USA, have conducted theoretical and empirical studies on the ecological niche since the early 1990s. The concept of the ecological niche was introduced in the early 1900s, developed in the mid-1900s, and advanced from the mid-1900s to the late 1900s. Since the 2000s, the advanced concept has diversified with new developments in technologies and research methods. The factors suggested by theoretical and empirical studies in defining the ecological niche of a species include 1) population dynamics of the target species, 2) all biotic conditions to sustain a population (food relationship and material flow in the food chain), 3) all non-biotic conditions to sustain a population (physical environmental conditions), 4) all direct and indirect interactions between these environmental factors, and 5) response and adaptation mechanisms that include the migratory ability of the target species or genetic diversity and adaptability to change. Unlike such international advancement, there have not been sufficient theoretical, philosophical, and empirical studies of ecological niche in Korea. The concepts and definitions by Greennell, Elton, and Hutchinson were selectively and partially borrowed for empirical studies without full description. Considering that the theory of ecological niche becomes the foundation for habitat-based species conservation and restoration, it is necessary to seek diversification and advancement of theoretical and empirical research and research methods and technological development. It will provide an important foundation for the academic advancement of ecology and for establishing and implementing policies to preserve and restore ecology and biodiversity effectively and successfully in Korea.

Anti-Inflammatory Effect of Essential Oils Extracted from Wood of Four Coniferous Tree Species (침엽수 4종 목부 정유의 항염증 효과 평가)

  • YANG, Jiyoon;CHOI, Won-Sil;KIM, Jae-Woo;LEE, Sung-Suk;PARK, Mi-Jin
    • Journal of the Korean Wood Science and Technology
    • /
    • v.47 no.6
    • /
    • pp.674-691
    • /
    • 2019
  • The aim of this study was to evaluate the anti-inflammatory effects of essential oils extracted from the wood of Chamaecyparis obtusa, Pinus densiflora, Pinus koraiensis, and Larix kaempferi. Essential oils were extracted by hydrodistillation, and their chemical components were determined by GC/MS. Major chemical components of these essential oils were ${\alpha}$-cadinol (19.25%), ${\tau}$-muurolol (14.20%), and ${\alpha}$-pinene (13.74%) in C. obtusa; ${\alpha}$-pinene (47.16%), longifolene (14.31%), ${\beta}$-phellandrene (11.78%), and ${\beta}$-pinene (11.02%) in P. densiflora; ${\alpha}$-pinene (13.49%) and longifolene (10.79%) in P. koraiensis, and geranyl linalool (23.58%) and ${\alpha}$-pinene (18.57%) in L. kaempferi. To evaluate the anti-inflammatory effects of essential oils, lipopolysaccharide (LPS)-induced RBL-2H3 mast cells were treated with these essential oils; then, the changes in the mRNA expression level of the cytokines IL-4 and IL-13 were examined. Further, degranulation was evaluated by measuring ${\beta}$-hexosaminidase release. After LPS-induced RBL-2H3 mast cells were exposed to $10^{-7}%$ of all types of essential oils, the gene expression levels of IL-4 and IL-13 within the cells remarkably decreased. The relative mRNA expression level of IL-4 was 69.6% in P. densiflora, 63.2% in P. koraiensis, 55.1% in C. obtusa, and 45.8% in L. kaempferi compared with that in the group treated with LPS. The mRNA expression level of L-13 should a similar trend. The inhibitory rate of IL-13 mRNA expression of P. densiflora, P. koraiensis, C. obtusa, and L. kaempferi was 57.8%, 57.1%, 51.1%, and 34.5%, respectively. ${\beta}$-Hexosaminidase release significantly decreased following the treatment with the four types of essential oils. The rate of ${\beta}$-hexosaminidase release were 38.1% C. obtusa; 33.0% P. densiflora; 27.4% P. koraiensis; and 9.1% L. kaempferi. Among all types of essential oils, that extracted from P. densiflora wood showed the highest anti-inflammatory activity. These results show that the tested essential oils exert an anti-inflammatory effect through the inhibition of degranulation and expression of cytokines.