• Journal of information and communication convergence engineering
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• 제17권1호
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• pp.14-20
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• 2019

Currently, microarray gene expression data take advantage of the sufficient classification of cancers, which addresses the problems relating to cancer causes and treatment regimens. However, the sample size of gene expression data is often restricted, because the price of microarray technology on studies in humans is high. We propose enhancing the gene expression classification of support vector machines with generative adversarial networks (GAN-SVMs). A GAN that generates new data from original training datasets was implemented. The GAN was used in conjunction with nonlinear SVMs that efficiently classify gene expression data. Numerical test results on 20 low-sample-size and very high-dimensional microarray gene expression datasets from the Kent Ridge Biomedical and Array Expression repositories indicate that the model is more accurate than state-of-the-art classifying models.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제26권3호
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• pp.165-172
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• 2023

Crohn's disease (CD) is a chronic, incurable and relapsing disease involving any part of the gastrointestinal tract and exclusive enteral nutrition (EEN) is first-line therapy. Few studies have examined the patient experience of EEN. The aim of this study was to assess the child's experiences of EEN, to identify problematic themes and understand the child's mindset. Children with CD who previously completed EEN were recruited to complete a survey. All data were analyzed using Microsoft Excel and reported as N (%). Forty-four children (mean age 11.3 years) consented to participate. Sixty-eight percent of children reported limited formula flavors as the most challenging aspect and 68% of children identified 'support' to be important. This study highlights the psychological impact of chronic disease and its therapies on children. Providing adequate support is essential to insure EEN is successful. Further studies are required to determine psychological support strategies for children taking EEN.

• Child Health Nursing Research
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• 제9권1호
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• pp.9-17
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• 2003

Families of children with cancer face many illness-related demands. The perceived social support is a critical resource for the family adaptation process. And the patterns of family adaptation to childhood cancer varies as characteristics of disease, which is prognosis, the influence of cognition function, and treatment process. The conceptual definition of social support is not unidimensional. However, most studies focus on general aspect of mediating effects on adaptation. Diverse dimensions of perceived social support should be considered in its effectiveness for intervention. Therefore, this study was undertaken to determine whether family's perceived social support influences the family adaptation of family with pediatric cancer and what dimension influences mostly in family adaptation as the characteristics of disease in the family of children with cancer. The subject was consisted of 102 families with pediatric cancer who had been diagnosed as leukemia or brain tumor last 2 years. Those families had participated in the education program or meetings for family who have with pediatric cancer children. The measurement for this study were Personal Resource Questionnaire (PRQ) Part-Ⅱ developed by Brandt and Weinert to measure parents' perceived social support, and the McCubbin's Coping Health Inventory for Parents (CHIP) to measure family coping. The results of this study can be summarized as follows; Regression analysis showed that perceived social support has effect on family adaptation with β=.43, p<.01. In the group of family of child with leukemia, social support as general has effect on adaptation (β=.40, p<.01) and specially, social support perceived as intimacy was strongly effect on family adaptation. And In the group of brain tumor, Social support has effect on adaptation(β=.46, p<.01) and among the social support domains, the self esteem dimension was most predictable to family adaptation. In conclusion, the perceived social support is a predictor on family adaptation and useful vehicle to help family who has child with pediatric cancer. An important clinical implication is that specified support program for intervention may be useful and critical for the family who has diverse pediatric conditions of childhood cancer. Further studies should stress the effects of family support for clinical intervention and is needed with diverse stage of development and pediatric conditions.

• 근관절건강학회지
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• 제3권1호
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• pp.63-89
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• 1996

This study has been done for the purpose of determining whether the positive association between social support and depression is attributable to an overall beneficial effect of support(direct effect) or to a process of support protecting persons from adverse effects of stressors such as life events, pain or physical disability (buffering effect). The sample consisted of 214 patients who were identified as the rheumatoid arthritis. The instruments used in this study were Depression Scale(CES-D), Perceived Social Support Scale, Life Events Questionnaire, AIMS Pain Scale, and Physical Disability Scale. The data were analysed by the use of t-test, ANOVA, Pearson Correlation Coefficient and Stepwise Multiple Regression. The results of this study are summerized as follows : 1. The 1st hypothesis, "The higher the life events degree, the higher the depression degree" was supported(r=.49, P=.0001). 2. The 2nd hypothesis, "The higher the pain degree, the higher the depression degree" was supported(r=.44, P=.0001). 3. The 3rd hypothesis, "The higher the physical disability degree, the higher the depression degree" was supported (r=.46, P=.0001). 4. The 4th hypothesis, "The higher the social support degree, the lower the depression degree" was supported(F=84.52, P=.0001). 5. The 5th hypothesis, "There will be different in the relationship between the degrees of life events and depression according to social support degree" was rejected (F=.29, P=.5928). 6. The 6th hypothesis, "There will be different in the relationship between the degrees of pain and depression according to social support degree" was supported (F=3.19, P=.0755). 7. The 7th hypothesis, "There will be different in the relationship between the degrees of physical disability and depression according to social support degree" was supported(F=5.69, P=.018). 8. The predictive variables for depression were the degrees for social support, life events, pain, and physical disability. 9. The depression degree showed a inverse correlation with social support degree (r=-.56, p=.0001). The social support degree showed a inverse correlation with the degrees of life events(r=-.22, p=.0007), pain(r=-.18, p=.0069) and physical disability(r=-.15, p=.0293). 10. The depression degree showed significant differences in the variables of sex (t=2.26, p=.025), educational level(r=.189, P=.006) and the number of treatment method (r=.201, P=.003). In conclusion, it was found that social support had the direct effect on depression and the buffering effect in each relationship between degrees of pain or physical disability and depression in patients with rheumatoid arthritis. So the researcher thinks that it is effective that nurses should provide these patients with social support to reduce depression in cases of having severe pain or physical disability.

• 대한방사선기술학회지:방사선기술과학
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• 제27권3호
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• pp.59-69
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• 2004

현대의학의 급속한 발전에도 불구하고 암은 아직도 인간에게 건강과 생명을 위협하는 주요인의 질환으로 인식되고 있다. 암은 세포조직의 과잉성장으로 인해 발생하는 악성종양으로 성별이나 연령에 관계없이 신체 어느 부분이나 발생하여 죽음에 이르게 하는 불치의 병으로 간주되고 있다. 암환자들이 치료를 받는 기간동안 겪게 되는 문제들은 심리적으로 우울하고, 죽음에 대한 불안감이 나타나며, 자아 존중감의 상실을 경험하게 된다. 방사선 치료를 받는 암환자는 대부분 수술이나 화학요법과 더불어 추가적으로 방사선치료를 병행하는 것으로 알려져 있어, 방사선 치료를 받는 환자는 신체적 고통뿐만 아니라 경제적이나 심리적으로 불안하고, 치료에 대한 부담감이 더욱 가중되어 환자에 대한 심리상태의 안정이 절실히 요구되고 있다. 인간의 질병에 대한 치료는 신체적 치료와 심리정서적 치료를 병행하여 시행함으로써 좀더 완전하고 효율적인 전인치료가 되는 것으로 알려져 있다. 본 연구는 방사선치료를 받는 암환자의 특성과 사회적 지지에 따른 심리상태를 확인하여 환자의 전인치료를 위한 기초 자료로 제공하고자 실시하였다.

• 대한한방부인과학회지
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• 제31권4호
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• pp.147-164
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• 2018

Objectives: This study was performed to analyze the pattern identification in infertile women who participated in infertility support program of Cheongju-city. Methods: The project proceeded from October, 2016 to June 2017. Participants filled in the questionnaire which is composed of 33 symptoms before korean medical treatments. Data were collected from 17 participants. We classified symptoms into six pattern identifications based on previous research and rated each answer to score. Results: Throughout the study, the average age of 26 patients was $34.88{\pm}3.19$ years old, the average height was $162.51{\pm}4.99cm$, and average weight was $58.41{\pm}7.88kg$. The average duration of acupuncture treatment was $121.03{\pm}52.73$ days and the average times of acupuncture treatment was $27.42{\pm}10.77$ times. The average number of herbal medicine treatment was $2.65{\pm}0.69$, the majority of it was Chokyungjongok-tang. After the treatment, 3 patients of infertility became pregnant (11.54%) in twenty six patients. By analyzing pattern identification survey papers, We can classify infertile women into 6 pattern identification based on previous research. The majority of participants was identified as Blood deficiency and the other participants were identified as Kidney deficiency, Liver depression, Dampness-phlegm, Qi deficiency and Static blood in order of priority. Most of patients' pattern identification were combined with two kind of pattern identification. In terms of priority, Liver depression combined with Kidney deficiency, Blood deficiency combined with Kidney deficiency, Liver depression combined with Qi deficiency, Liver depression combined with Dampness-phlegm. Conclusions: After the study we confirmed that Korean traditional medicine is a safe treatment for infertile women. Further clinical study about herbal medicines of patients who have combined pattern identification is needed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1435-1440
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• 2014

Background: It has been found that support given to women with breast cancer has a positive effect upon their reactions to the illness and may even prolong their survival. Perceived support needs assessment in breast cancer women could be considered as a necessary part of nursing function. Aim: The purpose of this study was to translate and culturally adapt the self-assessed support needs (SASN) questionnaire into Persian language and to investigate its psychometric properties. Materials and Methods: After forward-backward translation of the questionnaire and making appropriate changes, we selected 160 women with breast cancer as our study sample. The psychometric properties of the SASN, including its internal consistency, test retest reliability, and construct validity were evaluated through the known-groups technique. Results: The calculated Kaiser Meyer Olkin was 0.756, indicating that the sample was sufficiently large to perform a satisfactory factor analysis. The six factors all together explained 50.7% of the variance; the first factor (diagnosing) explaining the biggest part of variance (10.9). Internal consistency reliability was 0.83 for the whole scale and the stability of test was 0.78. For the first factor, Cronbach's alpha was 0.90 and factor loadings of scale's items were found to deal with diagnosis subscale. The domains described patients' diagnosis, treatment, support, femininity and body image, family and friends and information. Conclusions: The reliability and validity of the adapted version of the SASN was shown to be satisfactory. Thus, it can be used to investigate self-assessed support needs of Iranian women suffering from breast cancer since the SASN is a multi-domain scale.

• 대한불안의학회지
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• 제17권2호
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• pp.59-66
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• 2021

Objective : The purpose of this study is to investigate the relationship among the degree of symptoms of posttraumatic stress disorder (PTSD) and social support, stress coping strategies, and self-esteem in patients with PTSD. Methods : A total of 48 patients meeting DSM-5 criteria for PTSD and 48 normal controls were recruited for participation in this study. We evaluated subjects using the Clinician-Administered PTSD Scale (CAPS), Hamilton Anxiety Scale (HAM-A), Hamilton Depression Scale (HAM-D), Rosenberg Self-Esteem Scale (RSES), Multidimensional Scale of Perceived Social Support (MSPSS) and The Ways of Stress Coping Questionnaire (SCQ). We analyzed data using an independent t-test and Pearson's correlation analysis. Results : In PTSD patients, total CAPS scores showed a significant positive correlation with HAM-A and HAM-D scores and a significant negative correlation with MSPSS scores. RSES scores showed a significant positive correlation with MSPSS and SCQ scores. MSPSS scores showed a significant negative correlation with PTSD avoidance and numbing and HAM-D scores. SCQ scores showed a significant negative correlation with PTSD avoidance and numbing. Conclusion : These results revealed that the better the stress coping strategies and social support, the lower the degree of symptoms in patients with PTSD. In addition, it was found that the higher the social support and self-esteem, the lower the degree of depression and anxiety. Therefore, in the treatment process, it seems important to identify and correct the self-esteem, social support system, and stress coping strategies of patients with PTSD.

• 대한간호학회지
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• 제49권3호
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• pp.298-306
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• 2019

Purpose: This study aimed to examine the levels of perceived self-management support, self-efficacy for self-management, and health-related quality of life (HRQoL) in cancer survivors, and to identify the mediating effect of self-efficacy in the relationship between perceived self-management support and HRQoL. Methods: This study used a descriptive correlational design. Two hundred and four cancer survivors who had completed treatment participated in the study. Measurements included the Patient Assessment of Chronic Illness Care Scale, the Korean version of the Cancer Survivors' Self-Efficacy Scale, and the Medical Outcomes Study Short Form-36. Data were analyzed using descriptive statistics, Pearson's correlation coefficient analysis, and multiple regression analysis using Baron and Kenny's method for mediation. Results: The mean score for perceived self-management support was 3.35 out of 5 points, self-efficacy was 7.26 out of 10 points, and HRQoL was 65.90 out of 100 points. Perceived self-management support was significantly positively correlated with self-efficacy (r=.29, p<.001) and HRQoL (r=.27, p<.001). Self-efficacy was also significantly correlated with HRQoL (r=.59, p<.001). Furthermore, self-efficacy (${\beta}=.55$, p<.001) had a complete mediating effect on the relationship between perceived self-management support and HRQoL (Z=3.88, p<.001). Conclusion: The impact of perceived self-management support on HRQoL in cancer survivors was mediated by self-efficacy for self-management. This suggests that strategies for enhancing self-efficacy in cancer survivors should be considered when developing self-management interventions for improving their HRQoL.

• 성인간호학회지
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• 제22권5호
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• pp.529-536
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• 2010

Purpose: This study was designed to identify the effect of auriculotherapy on low abdominal pain and dysmenorrhea in school-aged girls. Methods: This design was a pre and post-test with nonequivalent groups. The subjects were 71 girls who were middle school students with dysmenorrheal (35 students for the treatment group and 36 students for the comparison group). The subjects of the treatment group received auriculotherapy once a week for 10 weeks. The comparison group received instruction on auriculotherapy and was requested waiting for the order. Results: The treatment group reported significantly less low abdominal pain than the comparison group. However, there were not statistical differences in reported dysmenorrhea. In future analysis, 60.0% of the treatment group reported more physical comfort, and 45.7% reported more emotional cool down. Conclusion: The finding indicate that auriculotherapy could be effective in decreasing low abdominal pain during menstrual periods. Therefore, auriculotherapy could be an effective nursing intervention for low abdominal pain occurring during mensuration. However, further studies need to be done to support auriculotherapy as effective.