• Archives of Reconstructive Microsurgery
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• v.20 no.2
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• pp.96-101
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• 2011

Reconstruction of soft tissue defect of knee joint area has been remained a challenging task for plastic surgeons. The earlier the normal tissue saved and the necrotic tissue removed, the less the patients had complications and functional disability. But such defects are difficult to manage for its poor vascularity, rigid tissue distensibility, easy infectability and a relatively long healing period. The goal of flap coverage in the knee joint should not only be satisfactory wound coverage, but also acceptable appearance and minimal donor site morbidity. We have treated five cases using the anterolateral thigh perforator flaps for reconstruction successfully. In conclusion, we believe that in cases of knee joint area soft tissue defects, flaps like anterolateral thigh perforator flap should be considered as the first line of treatment.

• Membrane and Water Treatment
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• v.1 no.1
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• pp.75-81
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• 2010

The aim of this work is to analyse and discuss the use of the Economic Evaluation and of some new "metrics" for an appropriate valuation of membrane operations in the logic of Process Intensification. In particular, the proposed approach has the goal to show how the utilized indicators can drive to the choice of the most convenient process. Although in this work the planned procedure is applied, as a case study, to the membrane-based systems for boron and arsenic removal from waters, the suggested approach can be generally applied to any other process of interest.

• IMMUNE NETWORK
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• v.9 no.6
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• pp.209-235
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• 2009

There has been an explosion of literature focusing on the role of regulatory T (Treg) cells in cancer immunity. It is becoming increasingly clear that Treg cells play an active and significant role in the progression of cancer, and have an important role in suppressing tumor-specific immunity. Thus, there is a clear rationale for developing clinical strategies to diminish their regulatory influences, with the ultimate goal of augmenting antitimor immunity. Therefore, manipulation of Treg cells represent new strategies for cancer treatment. In this Review, I will summarize and review the explosive recent studies demonstrating that Treg cells are increased in patients with malignancies and restoration of antitumor immunity in mice and humans by depletion or reduction of Treg cells. In addition, I will discuss both the prognostic value of Treg cells in tumor progression in tumor-bearing hosts and the rationale for strategies for therapeutic vaccination and immunotherapeutic targeting of Treg cells with drugs and microRNA.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.1
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• pp.54-57
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• 2016

Controlled ovarian hyperstimulation is one of the major steps of in vitro fertilization. The inaccessibility or non-visualization of developing follicles on transvaginal sonography (the preferred imaging method) may be misjudged as a poor response, resulting in cycle cancellation. It is necessary to scrupulously appraise proxy indicators for ovarian response, such as estradiol levels, endometrial thickness, and other individual clinical characteristics. This can prompt meticulous transabdominal ultrasound follicular monitoring and oocyte retrieval with the goal of averting cycle cancellation and improving treatment outcomes.

• 대한상한금궤의학회지
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• v.4 no.1
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• pp.49-55
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• 2012

Objectives : This research is to prove the effectiveness of DahuangMudan-Tang(大黃牡丹湯) in curing the Bartholin's duct abscess Methods : to achieve the goal of this research, the patient was diagnosed as 'abscess(腫膿)' treatabling by Dahuang(大黃) in GoBeob-medicine(古法醫學). I gave Dahuang Mudan-Tang(大黃牡丹湯) to the selected patient and observed the progress Results : the results indicate the followings 1. After the treatment with DahuangMudan-Tang(大黃牡丹湯), the symptoms of the Bartholin's duct abscess was significantly improved. 2. The external medicine with DahuangMudan-Tang(大黃牡丹湯) was more effective to cure the Bartholin's duct abscess.

• Transactions of Materials Processing
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• v.5 no.3
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• pp.219-231
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• 1996

The current five-stage cold extrusion process to produce an axle-housing is investigated for the purpose of improved process. The main goal of this study is to obtain an appropriate reduced process sequence which can produce the required part most economically without tensile crack-ing workpiece buckling and overloading of the tools. The current process sequence is simulated and design criteria are examined. during the simulation several remeshings are done due to severe mesh distortions, Based on the results of simulations of the current five-stage process, design strategy for improving the process sequence are developed using the thick hollow pipes. The finished product of an axle-housing is produced in two operations and one annealing treatment while the conventional sequence consists of five operations and one annealing treat-ment. Also die loads of the new process are compared with those of the current one.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.10a
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• pp.68-71
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• 2003

Heat treatment is one of the critical manufacturing processes that determine the quality of a product. This paper presents experimental and analytical results for the quench of a ring gear in stagnant oil. The goal of this study is to develop heat transfer predicting model in an overall analysis of the quenching process. Thermal conductivities which are dependant on temperatures and convection coefficients which are obtained by inverse method are used to develop the accurate heat transfer model. The results of heat transfer model have a good agreement with experimental results.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.8 no.1
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• pp.18-27
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• 1999

A tooth solely can not be an exclusive factor to attain our goal, esthetics. Other consideration, such a proportion of individual tooth, harmonized arrangement of the dentition and surrounding tissues including gingiva, lip and face should be taken into account. Esthetic gingival pattern and incisal level in the anterior area are the very important factors for esthetic restoration of the smile. We often propose adequate periodontal and prosthodontic approaches in order to improve the esthetics of the anterior area. Here, I would like to share some cases which include soft tissue management for ovate pontic placement, osteoplasty, resin filling for severe cervical caries, and bleaching approach to discolored root caused by endodontic treatment, and so on.

• Journal of Periodontal and Implant Science
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• v.28 no.4
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• pp.823-828
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• 1998

A primary goal of periodontal therapy is the creation of root surfaces that are free of plaque and calculus. It is not yet to be determined whether it is desirable to have a smooth root surface after treatment. It is also not clear what degree of roughness result from different instruments. In the present study various instruments for root surface debridement were evaluated. 20 extracted teeth were utilized, and the teeth were treated with one of the following instrument: Gracey curette, Perio Clean, and piezo ultrasonic device(Setlec, P Max) with general scaler tip, curette-like tip, and diamond tip. 3 dimensional planimetric device(Accura) was used to evaluate the average surface roughness. It was demonstrated hand and power-driven instruments did not have a significant difference in roughness of the root surface following instrumentation. And ultrasonic scaler tip tended to make a most smooth surface than other instruments. The possible reasons of the result were discussed.

• Radiation Oncology Journal
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• v.33 no.2
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• pp.57-65
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• 2015

Stereotactic body radiotherapy (SBRT) represents a consolidated treatment option for patients with medically inoperable early stage non-small cell lung cancer (NSCLC). The clinical evidence accumulated in the past decade supports its use as an alternative to surgery with comparable survival outcomes. Due to its limited toxicity, SBRT is also applicable to elderly patients with very poor baseline pulmonary function or other severe comorbidities. Recent comparative studies in operable patients raised the issue of the possible use of SBRT also for this subgroup, with quite promising results that still should be fully confirmed by prospective trials with long-term follow-up. Aim of this review is to summarize and discuss the major studies conducted over the years on SBRT and to provide data on the efficacy and toxicity of this radiotherapy technique for stage I NSCLC. Technical aspects and quality of life related issues are also discussed, with the goal to provide information on the current role and limitations of SBRT in clinical practice.