• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.4
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• pp.1-22
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• 2020

Objectives: The purpose of this review is to evaluate the efficacy of moxibustion for stress urinary incontinence (SUI) in women. Methods: For relevant randomized controlled trials (RCTs), we searched the following databases from their inception to September 1, 2020: The Cochrane Library, PubMed, EMBASE, Chinese National Knowledge Infrastructure Database (CNKI), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), and National Digital Science Library (NDSL). The key search terms were 'stress urinary incontinence' and 'moxibustion'. Data extraction and assessment of risk of bias were conducted by two authors independently. Results: A total of 11 RCTs were finally included in this systematic review. In all studies, moxibustion treatment was applied as an adjuvant therapy to the conventional treatment, and the most common conventional treatment was pelvic floor muscle training (PFMT). The treatment group (conventional treatment plus moxibustion) showed statistically more significant effect than the control group (conventional treatment only) in various evaluation indicators including urinary incontinence frequency, 1 hour urine pad test, quality of life, the clinical efficacy rate, and pelvic muscle strength. Conclusions: In this study, we investigated the efficacy of moxibustion as an adjuvant therapy for female SUI patients. Further studies are needed to supplement the safety of moxibustion and the evaluation of moxibustion dose.

• Journal of the Korea Convergence Society
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• v.12 no.6
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• pp.279-287
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• 2021

Purpose: The purpose of this study was to identify the relationships beween depression, self-efficacy and, treatment adherence in peritoneal dialysis patients. Method: Participants were 139 in a hospital located B city Korea. The data were examined using descriptive statistics, t-test, ANOVA, and Pearson's correlation with SPSS 25.0. Results: Self-efficacy had positive correlation with medication(r=.28 p=.001), fluid restriction(r=.23, p=.008), dietary restriction(r=.38, p<.001) in adherence. Depression had a negative correlation with medication(r=-.17 p=.046), dietary restriction(r=-.17, p=.043) Conclusion: Nursing starategies to strengthen the treatment adherence of patients with peritoneal dialysis need to focus on enhacing self-efficacy and alleviating depression.

• Clinical Endoscopy
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• v.56 no.6
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• pp.726-734
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• 2023

Background/Aims: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strictures. Methods: A systematic electronic literature search was performed (PROSPERO; no. CRD42022308033). The primary outcomes were technical success, efficacy, complication rate, and the need for further interventions due to reobstruction. The outcomes of partially covered self-expanding metal stents (PCSEMS) with scheduled retrieval after seven days were also analyzed. Results: Eleven eligible studies were included in the review. Overall, 173 patients with CD were included in this study. Mean percentage of technical success was 95% (range, 80%-100%), short-term efficacy was 100% in all studies, and long-term efficacy was 56% (range, 25%-90%). In patients with a scheduled PCSEMS retrieval, the long-term efficacy was 76% (range, 59%-90%), the mean complication rate was 35% (range, 15%-57%), and the major complication rate was 11% (range, 0%-29%). Conclusions: Endoscopic stenting with scheduled PCSEMS retrieval may be considered a feasible second-line treatment for short CD strictures to postpone surgery. However, larger head-to-head prospective studies are needed to understand the role of stenting as an alternative or additional treatment to EBD in CD.

• Korean Journal of Clinical Pharmacy
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• v.32 no.4
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• pp.336-351
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• 2022

Background: Prader-Willi Syndrome (PWS) is a rare genetic disorder. To improve the health deterioration of PWS, investigating optimal treatment options for PWS is required. Thus, we aimed to evaluate the efficacy of pharmacotherapies compared with supportive care or placebos in patients with PWS. Methods: PubMed and EMBASE databases were used to search for randomized controlled trials (RCTs) evaluating the efficacy of pharmacotherapy in PWS patients. Only RCTs that evaluating the efficacy of pharmacotherapy in PWS patients were retrieved. Results: A total of 26 studies were included to evaluate body composition, hormones, glucose levels and hyperphagia behavioral status. Pharmacological treatment group showed a significant decrease of body fat (mean difference (MD): -6.32, 95% confidence interval (CI): -10.58 to -2.06, p=0.004), a significant increase of lean body mass (LBM) (MD: 1.86, 95% CI: 1.43 to 2.30, p<0.00001) and insulin-like growth factor 1 (IGF-1) levels (MD: 241.62, 95% CI: 68.59 to 414.64, p=0.006) compared with the control group. Nevertheless, based on other outcomes evaluated by the current systematic review, pharmacological options showed different efficacy in treating PWS. Conclusion: Pharmacological therapies were effective to decrease significantly in body fat and increase significantly on LBM and IGF-1 levels in patients with PWS. However, still, individualized therapies should be considered in real-world practice in PWS treatment.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.54 no.4
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• pp.259-266
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• 2005

This paper presents a therapy that uses a constant drug dosage for leading HIV-infected patient to LTNP (Long-Term Non-Progressor). Based on analysis of CTLp (Cytotoxic T Lymphocyte precursor) concentration at equilibrium point and its bifurcation, we found the therapy with a drug whose efficacy is less than a certain level brings higher CTLp concentration at the equilibrium point. We observed a treatment with constant drug dosage whose efficacy is less than full treatment may lead HIV-infected patient to LTNP. It turns out that the treatment whose efficacy is less than full treatment is better in the point of performance on controllability.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.526-532
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• 2011

1. Objectives This study was designed to investigate the effect of Yanggyuksanhwa-tang(凉膈散火湯) to twelve hyperhidrosis patients. 2. Methods From May, 2008 to August, 2010, we treated hyperhidrosis patients with Yanggyuksanhwa-tang(凉膈散火湯). We survey demographic characters, symptoms of patients and efficacy of Yanggyuksanhwa-tang(凉膈散火湯). 3. Results 1) Twenties, thirties and males were more suffer from hyperhidrosis. 2) The patients who had dysuria got treatment efficacy negatively. 3) Treatment efficacy was affected by number of herbal medicine positively. 4. Conclusions This study shows that Yanggyuksanhwa-tang(凉膈散火湯) has effect to hyperhidrosis in Soeyangin. Treatment efficacy was affected by number of herbal medicine significantly.

• Korean Journal of Adult Nursing
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• v.26 no.1
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• pp.34-45
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• 2014

Purpose: The purpose of this study was to investigate the effect of laughter therapy and cognitive reinforcement program on self-efficacy, depression and cognitive functions of the elderly with mild cognitive impairments (MCI). Methods: The study design was a non-equivalent control group pre and posttest design. Thirty-six subjects over the age of 65 with a diagnosis of mild cognitive impairment were assigned either to a treatment or a comparison group. Data were collected from February 7 to March 27, 2012 in the dementia supporting center. An eight week treatment program that included laughter therapy coupled with a cognitive reinforcing program including hand exercise, laughter dance routine, laughter technic and cognitive training for attention, memory, orientation and execution skill. Results: MoCA-K (t=-6.86, p<.001) and Stroop test CW correct (t=-2.54, p=.008), self-efficacy (t=-3.62, p=.001) in the treatment group were significantly higher than those of the comparison group. Reported depression (t=2.29, p=.014), Stroop test CW error (U=53.50, p<.001) in the treatment group was significantly less than the comparison group. Conclusion: In this study, the treatment was effective in improving self-efficacy, cognitive function and reducing depression in the elderly with MCI.

• Proceedings of the Ginseng society Conference
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• 2004.12a
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• pp.59-60
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• 2004

• Journal of Korean Medical classics
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• v.24 no.5
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• pp.99-105
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• 2011

The medical treatment is process of collecting symptoms, making a diagnosis and treatment for the diagnosis. The remedy and the efficacy are the important hinge that links the diagnosis to the means of medical treatment. Lots of medical data are stored on database or saved as files in these days. The preferential way to find the efficacy related to the remedy is search all efficacy terms match up to the remedy term. To increase the rate of matching remedy terms with efficacy terms, we study the relation between efficacy terms and remedy terms and research the conversion way of the terms into the representative terms. The rate of matching the raw remedy terms with the raw efficacy terms is below 30%. The rate of matching the disaggregate remedy terms with the disaggregate efficacy terms is about 50%. The rate of matching the representative remedy terms with the representative efficacy terms is almost 70%.

• Tuberculosis and Respiratory Diseases
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• v.81 no.1
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• pp.6-12
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• 2018

The role of the treatment for latent tuberculosis infection (LTBI) has been underscored in the intermediate tuberculosis (TB) burden countries like South Korea. LTBI treatment is recommended only for patients at risk for progression to active TB-those with frequent exposure to active TB cases, and those with clinical risk factors (e.g., immunocompromised patients). Recently revised National Institute for Health and Care Excellence (NICE) guideline recommended that close contacts of individuals with active pulmonary or laryngeal TB, aged between 18 and 65 years, should undergo LTBI treatment. Various regimens for LTBI treatment were recommended in NICE, World Health Organization (WHO), and Centers for Disease Control and Prevention guidelines, and superiority of one recommended regimen over another was not yet established. Traditional 6 to 9 months of isoniazid (6H or 9H) regimen has an advantage of the most abundant evidence for clinical efficacy-60%-90% of estimated protective effect. However, 6H or 9H regimen is related with hepatotoxicity and low compliance. Four months of rifampin regimen is characterized by less hepatotoxicity and better compliance than 9H, but has few evidence of clinical efficacy. Three months of isoniazid plus rifampin was proved equivalence with 6H or 9H regimen in terms of efficacy and safety, which was recommended in NICE and WHO guidelines. The clinical efficacy of isoniazid plus rifapentine once-weekly regimen for 3 months was demonstrated recently, which is not yet introduced into South Korea.