• Title/Summary/Keyword: Treatment Effects

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Effect of Gamma Irradiation for Hygienic Long-Term Storage on Biological Activity of Teucrium veronicoides (위생적인 장기 보존을 위한 감마선 조사가 곽향(Teucrium veronicoides)의 생리활성에 미치는 영향)

  • Park, Hye-Jin;Park, Ki-Tae;Cho, Young-Je
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.46 no.5
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    • pp.581-591
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    • 2017
  • The purpose of this study was to examine the biological activities of gamma-irradiated Teucrium veronicoides. In photostimulated luminescence analysis, non-irradiated sample showed lower than 700 photon counts (PCs), whereas irradiated (5 and 10 kGy) samples showed higher than 700 PCs. The thermoluminescence ratio of non-irradiated samples was less than 0.1, whereas the values of irradiated samples were greater than 0.1. Electron spin resonance analysis was performed confirmed for irradiation identification. The total phenolic contents of hot-water and 50% ethanol extracts were higher than those values after irradiation at 10 kGy. Regarding 1,1-diphenyl-2-picrylhydrazyl radical inhibitory activity, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity, antioxidant protection factor, thiobarbituric acid reactive substance inhibitory activity as antioxidant test and xanthine oxidase inhibitory activity, the effect of gamma irradiation had on significant effects. On the other hand, ${\alpha}-amylase$ inhibitory activity of 10 kGy-irradiated hot-water extract was 23.6% higher than that of the non-irradiated sample. Thus, gamma irradiation could be used for the long-term storage of Teucrium veronicoides.

Survey of Sedation Practices by Pediatric Dentists (소아치과의사의 진정법 사용에 대한 실태조사)

  • Yang, Yeonmi;Shin, Teojeon;Yoo, Seunghoon;Choi, Seongchul;Kim, Jiyeon;Jeong, Taesung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.41 no.3
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    • pp.257-265
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    • 2014
  • The aim of this study was to establish the appropriate guidelines in the sedation techniques and to organize the continuing education programs for the sedation in future under the direction of Committee on Sedation, Education and Research under the Korean Academy of Pediatric Dentistry(KAPD). The surveys on the sedation technique were performed on 111 organizations which practices the sedation and responded to the survey via online and e-mail by February 2014. The collected survey were analyzed. The purpose of sedation was mainly to manage the children's behavior and its uses were primarily on 3~4 years old children. The most frequent duration of treatment was 1~2 hours to treat both maxillary and mandible. The preferred dosages of sedative drugs were chloral hydrate(CH) 50~70 mg/kg, hydorxyzine(Hx) 1~2 mg/kg, and intramuscular midazolam(Mida IM) 0.1~0.2 mg/kg. The preferred combination of the sedative drugs were CH + Hx + $N_2O/O_2$(67.6%), CH + Hx + Mida submucosal administration (SM) + $N_2O/O_2$(29.7%), and Mida IM + $N_2O/O_2$(23.4%). The administration of additional sedatives was carried out at 48%, mainly using Midazolam. 87.5% of the respondents experienced the adverse effects of the sedation such as vomiting/retching, agitation during recovery, subclinical respiratory depression, staggering, and etc. Among them, only 20% periodically retrain the emergency management protocol. About the discharge criteria for patients after the sedation, the respondents either showed a lack of clear criteria or did not follow the recommended discharge criteria. 86% of the respondents expressed the interests in taking a course on the sedation and they wanted to learn mostly about the sedation-related emergency management, the safe dosage of the sedative drugs, and etc. The use of sedation in pediatric dentistry must be consider a patient's safety as top priority and each dentist must show the evidence of sound practices for the prevention of any possible medical errors. Therefore, KAPD must establish the proper sedation guidelines and it needs to provide the systematic technical training program of sedation-related emergency management for pediatric dentists.

Effects of Beverage Using Herbs on the Antimicrobial, Anticancer and Antiallergy Activities (약초 음료의 항균효과, 항암효과 및 알레르기 억제효과 검증)

  • Park, Eun-Mi;Ye, Eun-Ju;Kim, Soo-Jung;Kim, Sol-Ah;Bae, Man-jong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.7
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    • pp.953-958
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    • 2005
  • This study was conducted to investigate the effect of beverage (beverage HC and beverage PG) using herbs on antimicrobial activity, proliferation of hepatic cancer cell (Hep3B) lines and sarcoma 180 (S-180) and antiallergy, respectively. Beverage PG showed higher antimicrobial activity than beverage HC against Staphylococcus aureus and Pseudomonas aeruginosa. Beverage HC and PG showed the tumor suppressive effect in mice injected with S-180 cells. The growth-inhibitoy ratio against tumor cells were $66\%\;for\;10\%$ beverage HC, $61\%\;for\;10\%$ beverage PG. In an anti-cancer test using Hep3B cells, beverage PG showed higher anti-proliferating effect than beverage HC. Beverage PG showed growth-inhibitory effect of $69.2\%\;at\;100\%$ beverage PG. Beverage PG inhibited histamine release from rat peritoneal mast cells (RPMC) activated by compound 48/80. In conclusion, these results suggest that beverage using herbs have an antimicrobial activity, anti-proliferating effect against Hep3B cell and S-180 tumor and will be beneficial in treatment of allergic reaction.

Protective Effects of Chaenomeles sinensis Koehne Extract on Ethanol-induced Liver Damage in Rat (에탄올에 의해 유발된 간독성에 대한 모과 추출물의 보호효과)

  • Lee, Yu-Mi;Lee, Jae-Joon;Shin, Hyoung-Duck;Lee, Myung-Yul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1336-1342
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    • 2006
  • This study was performed to investigate the effect of ethanol extract of Chaenomeles sinensis Koehne (CS) on alcohol-induced liver damage in rats. Male Sprague-Dawley rats weighing $135{\pm}10g$ were divided into 6 groups for 4 weeks; normal group (ND), alcohol (35%, 10 mL/kg/day) treated group (ET), CS ethanol extract 200 mg/kg/day treated group (ND-CSL), CS ethanol extract 400 mg/kg/day treated group (ND-CSH), CS ethanol extract 200 mg/kg/day and alcohol treated group (ET-CSL), and CS ethanol extract 400 mg/kg/day and alcohol treated group (ET-CSH). The body weight gain and food efficiency ratio were no differences between ND and ET. There were increases in the activities of serum alanine aminotransferase (ALT), asparate aminotransferase (AST), and alkaline phosphatase (ALP) in ET. On the other hand, the administration of CS decreased ALT, AST and ALP activities in serum. It was also observed that the hepatic activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px) and xanthine oxidase (XO) increased by alcohol treatment were also markedly decreased in the CS administered groups as compared with ET. The activities of hepatic SOD, catalase, GSH-Px and XO were riot significantly different among the normal diet groups. Contents of thiobarbituric acid reactive substances (TBARS) were increased by the administration of alcohol, on the other hand, the administration of CS reduced TBARS value in the liver. In addition, the content of glutathione (GSH) in the liver was decreased by alcohol administration, however, GSH increased after administering CS. In conclusion, the administration of alcohol develops the hyperoxidation of liver lipids through tile increase in enzymes activity related to the lipid peroxiation, however, it was decreased after administring CS. Thus, CS may have a possible protective effect on ethanol-induced hepatotoxicity in rat liver.

Effects of Controlling the Pine Needie Gall Midaes by Salicylic Acid Content in Needles of Some Pinus spp. (소나무류(類) 침엽내(針葉內)의 salicylic acid에 의한 솔잎혹파리의 방제효과(防除效果))

  • Son, Doo-Sik;Eom, Tae-Jin;Choi, Chang-Ok;Zhang, Ruo Ming
    • Journal of Korean Society of Forest Science
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    • v.88 no.1
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    • pp.31-37
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    • 1999
  • The frequency of gall formation by pine needle gall midges ranged from 35% to 40% in both P. densiflora and P. thunbergii species. However, there was no indication of gall development from larva on both P. virgiana and P. rigida species suggesting that some specific compounds might play role in preventing gall formation of larva. The susceptible species to pine needle gall midges including P. densiflora and P. thunbergii contained a little salicylic acid under the free phenolic compound conditions while the resistant species against such insects including P. virginiana and P. rigida species contained about 37ppm to 50ppm of salicylic acid. Thus, this compound might have important roles in insect resistance. The contents of internal salicylic acid in the needles of susceptible pines increased from 9.5ppm to 20.6ppm after direct external irrigation of salicylic acid solution and flour treatment on roots. As a result, the frequency of gall formation decreased dramatically 17~19 times lower when compared with that of control. According to our results, the application of salicylic acid for effective prevention against insect damages should be performed before hatching eggs. The frequency of gall formation in the hybrid pines of P. thunbergii(susceptible) and P. virginiana(resistant) showed approximately 24% as average value of those in both species. In the case of specific individuals, it ranged from 2.8% to 11.5% in hybrids of both species. Therefore, effective production of insect resistant pines can be obtained through hybrids by crossing between susceptible and resistant species including P. thunbergii and P. virginiana by increasing internal salicylic acid contents of the needles.

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Optimizing Surfactant-Enhanced Solubilzation of LNAPL from Soil in Saturated Zone (포화지층내 저비중 비수용성 유기용매의 용해제거를 위한 계면활성제법의 최적 조작인자 도출)

  • 이재원;박규홍;박준범
    • Journal of the Korean Geotechnical Society
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    • v.15 no.2
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    • pp.153-164
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    • 1999
  • The solubilization of BTEX was evaluated in aqueous surfactant solutions with and without several additives. Anionic surfactant(Sodium Dodecyl Sulfate, SDS) and nonionic surfactants (NEODOL(equation omitted)25-3 and $SOFTANOL\circledR-90$ were used as test surfactants. The effects of surfactant HLB(Hydrophile-Lipophile Balance) Number and hydrocarbon molar volume and polarity of BTEX on the MSR(Molar Solubilization Ratio), micelle-water partition coefficient of BTEX, and CMC(C,itical Micelle Concentration) were investigated. Optimizing treatment conditions applicable to enhanced solubilization was also studied by manupulating salinity or electrolyte control with additives of ethyl alcohol, hydrotrope, and electrolyte solution. The most effective surfactant for solubilization was found $SOFTANOL\circledR-90$, since HLB number of 13.6 is similar to those values of BTEX ranging between 11.4 and 12.2, which was also proved experimentally. Ethyl alchohol of 3% was the most effective additives in reducing CMC and improving solubilization among the conditions using SDS, NEODOL(equation omitted)25-3, and $SOFTANOL\circledR-90$ with three additives. The partitioning of BTEX between surfactant micelles and aqueous solutions was characterized by a mole fraction micelle-phase/aqueous phase partion coefficient, $K_m$. Values of log $K_m$. for BTEX compounds in surfactant solutions of this study range from 2.95 to 3.76(100mM SDS) and 2.95 to 3.49(117mM $SOFTANOL\circledR-90$. Log $K_m$ appears to be a linear function of log $K_{ow}$ for SDS and $SOFTANOL\circledR-90$. A knowledge of partitioning of BTEX in aqueous surfactant system can be a prerequisite for the understanding of the behavior of hydrophobic organic compounds in soil-water systems in which surfactants play a role in remediation of contaminated soil and facilitated transport.

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Antibacterial effects of Chitosanon-ascorbate Treated Kwamaegi Prepared on Microorganism Contamination (Chitosan-ascorbate 처리 과메기에 있어서 오염미생물에 대한 저해효과)

  • Kim, Young-Sook;oh, Seung-Hee;Kim, Soon-Dong
    • KSBB Journal
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    • v.24 no.2
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    • pp.156-162
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    • 2009
  • We examined saury, herring, gizzard shad kwamaegi to measure of microbic contamination rate of kwamegi that are sold in the market now. In the total bacteria, staphylococcus, peroxide value, and microorganisms is inhibited that from sample that we treated a substance with chitosan-ascorbate (CA) and other orders deep water (DW), ginseng steamed red and wine (GRW), NT (not treated). When we compared between SGRW and SNT, SCA show us more inhibition effect 0.22-0.49 log cycle in the total aerobacter. When we compared between HDW and HNT, HCA restraint 0.05-0.45log cycle, and when we compared between GDW and GNT, GCA inhibited 0.45 log cycle. In the coliform and E. coli, growths of microorganisms were inhibited followed order by treatment of CA, NT, and DW. GDW, HCA and HNT checked enough amount of water from the moisture measurement; but SGW, GCA, HEW and SCA showed 7-15% lack of moisture, and SNT and GNT have 10% more moisture. Peroxide value is changed to 41-51meq/kg when we did treat CA in there and a side that didn't add antimicrobial expressed the result numerically that 56-58meq/kg. In the sensory evaluation, customer gave preference to followed by Saury kwamaegi, herring, and gizzard shad kwamaegi. We have a point of view when kwamaeki manufactured if we add natural antibiotic and it uses to vacuum drying, we would inhibited of multiplication of microorganism, and of peroxides.

Investigation of Requirement and Demand toward for Functional Traditional Hangwa(Korean Cookies) of Tradition (기능성 전통 한과류 요구도 및 수요도 조사)

  • Bok, Hye-Ja;Choi, Soo-Keun
    • Journal of the East Asian Society of Dietary Life
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    • v.18 no.5
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    • pp.692-701
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    • 2008
  • This study was conducted with 150 adults of 20 years or older, all of whom lived in Seoul. The awareness of traditional Hangwa (Korean cookies) was shown to be relatively low, with 2.9 points on average, and the intake of traditional Hangwa for a month was 2.1 times. For the reason that traditional Hangwa couldn't become popular, and the opinion that the reason was because the price is expensive was the highest, at 3.8. The next highest reasons given were because it is difficult to buy, and because it is inconvenient to eat, at 3.0. The traditional Hangwa was shown to enjoy positive awareness as opposed to negative awareness, while the manufacturing sanitation was also recognized to be relatively clean, with 2.6 points assigned to the opinion that it doesn't taste good, and 2.7 points assigned to the opinion that the manufacturing sanitation is unclean. With regard to the excellence of traditional Hangwa, the response that 'our tradition can be handed down' was the most often encountered, with a score of 3.9. The traditional Hangwa was appraised as excellent, with 3.6 points assigned to the opinion 'it suits our body because it is made with our agricultural products' and 3.4% for each opinion 'safe ingredients are used' and 'all ingredients are good for health'. With regard to the level of agreement for the development of functional traditional Hangwa, the positive group was higher than 25.3% of the negative group, with 27.3% for 'agree very much' and 22.0% for 'agree'. When converted into a 5-point scale for the development of functional traditional Hangwa, the group that was positive toward its development was high, with 3.4 points on average. All categories of excellence awareness were correlated with the level of agreement for the development of a functional food product (p<0.001). Consumer awareness toward the addition of traditional Hangwa functionality was generally positive, with 3.3 points or higher on average, and awareness of the aging suppression and diabetes control effects of Hangwa was also high, with 3.5 points. Next were Hangwa for diet, Hangwa for blood pressure control, Hangwa for mineral supple-mentation and vitamin additive-type Hangwa, with 3.4 for each, and Hangwa for health preservation, with 3.3 in order. With regard to the degree of interest toward functional traditional Hangwa for the treatment of diseases, obese patients cited aging suppression, at 3.2, and vitamin additive Hangwa, at 3.0, while Hangwa for dieting was assigned 2.8 points. Patients with high blood pressure, blood circulation, and diabetes were all shown as having a high degree of interest in all items, while evidencing particular interest toward Hangwa for diabetes control and Hangwa for blood pressure control. With regard to intention to purchase while developing functional traditional Hangwa, the group asserting intention to purchase was higher than 60% for all items except for Hangwa for diabetes control (58.7%). The Hangwa for aging suppression was highest, at 68.6%, and shown as having intention to purchase during development in the order of vitamin additive Hangwa at 68.0%, Hangwa for mineral supplementation at 64.6%, each of Hangwa for health preservation and Hangwa for blood pressure control at 62.7%, Hangwa for diet at 62.6% and Hangwa for diabetes control at 58.7%. The considerations during the development of functional traditional Hangwa were in the following order: storage at 4.1 points, taste and level of function at 3.9 points, size at 3.5 points, and packing at 3.4 points.

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Effects of Seed Coating and Molding on Seed Germination and Seedling Growth of Rehabilitating Plants in Forest Road Slopes (임도 비탈면 녹화식물의 종자피복 및 복토처리가 발아와 생장에 미치는 영향)

  • Lee, Byung-Tae;Park, Chong-Min
    • Korean Journal of Environment and Ecology
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    • v.20 no.4
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    • pp.436-447
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    • 2006
  • Recently, there is increasing demand on enhancing the efficiency of hydro-seed spraying in afforestation for damaged or degraded land including forest road slopes. In this study, we focus on how seed coating and molding may affect seed germination and seedling growth. Plant species used in the study are Lespedeza cyrtobotrya, Indigofera pseudotinctoria, Arudineila hirta, Poa pratensis, and Lolium perenne. The results of seed germination and seedling growth with and without seed coating and molding are analyzed as follows: 1. For all the species and in both seeding with molding covered with soil and seeding without molding in which seeds were over sown, the increment of germination ratio by seed coating method is greater than by non·coating one. Seed coating increases average germination ratios observed in seeding with molding and without molding by 11.2% and 21.4%, respectively. Germination force may decrease from 0.8 to 3.7 days depending on the plant species and the treatments. The $LD_{50}$ decreased by $0.8{\sim}2.6$ days. However, seed coating delays the start of germination by approximate 1 day for all of the observed plants. 2. Seed coating may have the effect of accelerating the growth of stem and leaf and root. The experimental result shows that seed coating leads to 21.7% and 34.8% increment of average stem and leaf growth by seeding with molding and without molding, respectively. In terms of root growth, seeding with molding results in 22.0% increment while seeding without molding produces 26.2% increased root growth. 3: Compared to seeding without molding, germination starts on an average of 1.3 days later in seeding coated seeds with molding. However. the germination ratio is increased by 5%, and germination force and $LD_{50}$ are observed to shorten by 1.0 day and 1.4 days, respectively. Meanwhile, whether seeds are coated or not may be more related with germination and seedling growth in seeding without molding than with those in seeding with molding. 4. In this study, coating materials are examined to look at which ones are better in each treatment. Coating with Vermiculite+Talcum is the most effective in germination and seedling growth for overall plants. Seed coating using Bentonite, Calcium Carbonate, and Calcium Hydroxide shows better results than non-coating does. 5. When seeds are coated, the greatest enhancement of seed germinations was observed in Indigofera pseudotinctoria and, in the case of seedling growth, Lespedeza cyrtobotrya has the most increasing observation value among the 5 examined species. These results may indicate that woody plant seeds, having greater sizes of seeds than ones of grass seeds, may have greater relation with seed coating than grass plant seeds may have. 6. Therefore, if seeds cannot be molded up after hydro-seeding on forest road slopes, it is recommended that seeds for restoration be pre-coated with Vermiculite+Talcum and then be sowed, in order to quickly stabilize the damaged slope and achieve successful afforestation.

A Pilot Study in Cognition and Attitude of Nursing Students on Oriental Nursing (한방간호에 대한 간호학생들의 인식 및 태도에 대한 예비연구)

  • Han, Sang-Sook;Kim, Won-Ock;Hyun, Kyung-Sun;Won, Jeong-Sook;Choi, Kyung-Ock;Chang, Kyung-Hwa;Lee, Mi-Aie;Kim, Sook-Young;Jeon, Eun-Young;Kim, Jeong-Sook;Lee, Eun-Sook;Bae, Yeong-Suk
    • Journal of East-West Nursing Research
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    • v.8 no.1
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    • pp.81-88
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    • 2003
  • This research has been conducted to examine the cognition and attitude of nursing students on Oriental Nursing, the subject of this research being 789 nursing students from 9 different universities who took the Oriental Nursing class. A questionnaire, the construct validity and reliability of which have been verified through enquiries into records and references as well as preliminary researches, was used as a research tool. The questionnaire, a set of 86 questions, was developed by the researchers of this study, and the reliability of the questionnaire is Cronbach's=.85. The collected data have been analysed using SPSS windows programme 11.0 for t-test and ANOVA, and the results are as follows: 1. There was a significant difference in cognition and attitude points according to the academic year (F=14.15, p=.000). After the post-hoc test, it was revealed that the points of the students in their 4th year were significantly higher than the points of the students in their 2nd or 3rd year. 2. There was a significant difference in cognition and attitude points according to the credits the students have taken (F=28.66, p=.000). After the post-hoc test, it was revealed that the points of the students who have taken from $3{\sim}5$ to $6{\sim}8$ credits were significantly higher than the points of those who have taken from 1 to 2 credits. 3. There was a significant difference in cognition and attitude points according to the period of time the students have experienced Oriental Nursing (F=32.06, p=.000). After the post-hoc test, it was revealed that the points of the students who have practised Oriental Nursing from 1 to 2 weeks were significantly higher than the points of those who have not practised it at all. 4. There was no significant difference in cognition and attitude points according to the treatment or hospitalisation of the students themselves or their family members. 5. The cognition and attitude points of the students who are deeply interested in Oriental Nursing were significantly higher than the points of those who are not (t=8.83, p=.000). 6. The cognition and attitude points of the students who have higher expectations for the development of Oriental Nursing were significantly higher than the points of those who have not(t=5.90, p=.000). 7. The cognition and attitude points of the students who believe that the Oriental Nursing will contribute to the expansion of the roles of nurses were significantly higher than the points of those who do not (t=6.60, p=.000). 8. The cognition and attitude points of the students who expect that the Oriental Nursing will be effective in prevention of chronic diseases were significantly higher than the points of those who do not (t=5.80, p=.000). According to the results above, it was confirmed that proper education on Oriental Nursing can have affirmative effects on the cognition and attitude of the nursing students towards Oriental Nursing.

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