• 한국운동역학회지
• /
• 제27권1호
• /
• pp.35-43
• /
• 2017

Objective: The purpose of this study was to determine how gaze angle affects muscle activity and kinematic variables during treadmill walking and to offer scientific information for effective and safe treadmill training environment. Method: Ten male subjects who have no musculoskeletal disorder were recruited. Eight pairs of surface electrodes were attached to the right side of the body to monitor the upper trapezius (UT), rectus abdominis (RA), erector spinae (ES), rectus femoris (RF), bicep femoris (BF), tibialis anterior (TA), medialis gastrocnemius (MG), and lateral gastrocnemius (LG). Two digital camcorders were used to obtain 3-D kinematics of the lower extremity. Each subject walked on a treadmill with a TV monitor at three different heights (eye level; EL, 20% above eye level; AE, 20% below eye level; BE) at speed of 5.0 km/h. For each trial being analyzed, five critical instants and four phases were identified from the video recording. For each dependent variable, one-way ANOVA with repeated measures was used to determine whether there were significant differences among three different conditions (p<.05). When a significant difference was found, post hoc analyses were performed using the contrast procedure. Results: This study found that average and peak IEMG values for EL were generally smaller than the corresponding values for AE and BE but the differences were not statically significant. There were also no significant changes in kinematic variables among three different gaze angles. Conclusion: Based on the results of this study, gaze angle does not affect muscle activity and kinematic variables during treadmill walking. However, it is interesting to note that walking with BE may increase the muscle activity of the trapezius and the lower extremity. Moreover, it may hinder proper dorsiflexion during landing phase. Thus, it seems to reasonable to suggest that inappropriate gaze angle should be avoided in treadmill walking. It is obvious that increased walking speed may cause a significant changes in biomechanical parameters used in this study. It is recommended that future studies be conducted which are similar to the present investigation but using different walking speed.

• Nutrition Research and Practice
• /
• 제10권2호
• /
• pp.161-166
• /
• 2016

BACKGROUND/OBJECTIVES: Energy production and the rebuilding and repair of muscle tissue by physical activity require folate and vitamin $B_{12}$ as a cofactor. Thus, this study investigated the effects of regular moderate exercise training and durations of acute aerobic exercise on plasma folate and vitamin $B_{12}$ concentrations in moderate exercise trained rats. MATERIALS/METHODS: Fifty rats underwent non-exercise training (NT, n = 25) and regular exercise training (ET, n = 25) for 5 weeks. The ET group performed moderate exercise on a treadmill for 30 min/day, 5 days/week. At the end of week 5, each group was subdivided into 4 groups: non-exercise and 3 exercise groups. The non-exercise group (E0) was sacrificed without exercising and the 3 exercise groups were sacrificed immediately after exercising on a treadmill for 0.5 h (E0.5), 1 h (E1), and 2 h (E2). Blood samples were collected and plasma folate and vitamin $B_{12}$ were analyzed. RESULTS: After exercise training, plasma folate level was significantly lower and vitamin $B_{12}$ concentration was significantly higher in the ET group compared with the NT group (P < 0.05). No significant associations were observed between plasma folate and vitamin $B_{12}$ concentrations. In both the NT and ET groups, plasma folate and vitamin $B_{12}$ were not significantly changed by increasing duration of aerobic exercise. Plasma folate concentration of E0.5 was significantly lower in the ET group compared with that in the NT group. Significantly higher vitamin $B_{12}$ concentrations were observed in the E0 and E0.5 groups of the ET group compared to those of the NT group. CONCLUSION: Regular moderate exercise training decreased plasma folate and increased plasma vitamin $B_{12}$ levels. However, no significant changes in plasma folate and vitamin $B_{12}$ concentrations were observed by increasing duration of acute aerobic exercise.

• 디지털융복합연구
• /
• 제14권11호
• /
• pp.357-367
• /
• 2016

본 연구에서는 가상현실 기반 신경근 자세조절 융합 훈련을 이용하여 기능적 발목 불안정성을 가진 축구선수들의 균형 능력과 점프 수행력에 미치는 효과에 대하여 알아보고자 하였다. 축구선수는 가상현실 기반 신경근 자세조절 융합 훈련군 15명과 일반적인 트레드밀 훈련군 15명으로 나누어 8주간 주 3회, 30분간 시행하였고, 균형 능력을 평가하기 위해 Biorescue를 이용하여 신체 중심 이동면적, 총 궤적길이, 안정성 한계를 측정하였다. 점프 수행력을 측정하기 위해 Counter movement jump with arm swing과 제자리 멀리 뛰기를 측정하였다. 균형 능력 비교에서는 신체 중심 이동면적과 총 궤적 길이 및 안정선한계에서 통계적으로 유의한 차이를 보였고, 점프 수행력 비교에서는 Counter movement jump with arm swing과 제자리 멀리 뛰기에서 통계적으로 유의한 차이를 보였다. 이에 따라 가상현실 기반 신경근 자세조절 융합 훈련이 일반적인 트레드밀 훈련 보다 균형 능력과 점프 수행력을 향상시키는데 효과적임을 알 수 있었다.

• 운동영양학회지
• /
• 제13권2호
• /
• pp.161-167
• /
• 2009

The purpose of this study was to investigate whether two different exercises, acute exhaustive exercise and long-term endurance exercise training could affect to the expression of Mn-SOD, HSP70, and PPAR-γ protein in myocardium. The Wistar-Kyoto rats(n=24, 4 weeks) were used and randomly divided into 3 groups; endurance exercise training group (EET, n=8), acute exhaustive exercise group (AEE, n=8) or control group (CON, n=8). EET performed treadmill exercise for 12 weeks (5 days/week, 30~60 min/day). AEE exercised treadmill running (speed increased gradually to 14-26 m/min, 60 min ±10min) until exhausted when EET finished the program. Then, all the rats were sacrificed 48 hours rest at least after the last session of their own exercise program. Hearts were isolated and then the expression of Mn-SOD, HSP70, and PPAR-γ were analyzed by western blotting. One-way repeated ANOVA was used and p value under 0.05 was considered as statistical significance. The results were followed as; the expression of Mn-SOD of AEE was decreased compared with CON. However, the expression of Mn-SOD of EET was increased compared with CON. There was significant difference between AEE and EET in the expression of Mn-SOD. The expressions of HSP70 and PPAR-γ in the both AEE and EET were significantly increased compared with CON. In conclusion, acute exhaustive exercise might induce oxidative stress wheres endurance exercise training could ameliorate the oxidative conditions by increase of Mn-SOD, HSP70, and PPAR-γ. Therefore, we suggested that endurance exercise training could enhance the complementary antioxidant system and improve to prevent apoptosis. Further, a long-term moderat aerobic exercise program might play a important role in mitochondrial biogenesis in the heart.

• 대한물리의학회지
• /
• 제15권4호
• /
• pp.163-174
• /
• 2020

PURPOSE: This study examined the effects of Robot Tilt-table Training (RTT) on the lower extremity strength, balance, gait, and satisfaction with rehabilitation, in patients with subacute stroke (less than six months after stroke onset), and requiring intensive rehabilitation. METHODS: A total of 29 subacute stroke patients were divided into an RTT group (n = 14) and a Body Weight Support Treadmill Training (BWSTT) group (n = 15). The mean age of patients was 62 years. RTT and BWSTT were performed for four weeks, three times a week, for 30 minutes. Isometric strength of the lower extremities before and after intervention was compared by measuring the maximal voluntary isometric contraction of the lower extremity muscles. To compare the balance function, the center of pressure (COP) path-length and COP velocity were measured. Timed Up & Go test (TUG) and 10 Meter Walking Test (10 MWT) were evaluated to compare the gait function. A satisfaction with rehabilitation survey was conducted for subjective evaluation of the subject's satisfaction with the rehabilitation training imparted. RESULTS: In the intra-group comparison, both groups showed significant improvement in lower extremity strength, balance, gait, and satisfaction with rehabilitation, by comparing the parameters before and after the intervention (p < .05). Comparison of the amount of change between groups revealed significant improvement for all parameters in the RTT group, except for the 10 MWT (p < .05). CONCLUSION: Both groups are effective for all variables, but the RTT group showed enhanced efficacy for variables such as lower extremity strength, balance, gait, and satisfaction with rehabilitation, as compared to the BWSTT group.

• 한국응용과학기술학회지
• /
• 제41권1호
• /
• pp.58-68
• /
• 2024

본 연구의 목적은 알츠하이머질환(Alzheimer's disease: AD) 동물 모델을 대상으로 트레드밀 운동(Treadmill exercise: TE)과 환경강화(environmental enrichment: EE) 처치가 인지기능, 근 기능, 및 밀착연접 단백질 발현에 미치는 영향을 확인하는데 있다. AD 동물 모델을 제작하기 위해 aluminum chloride(AlCl₃)를 90일간(40mg/kg/하루) 투여 하였으며 동시에 TE(10-12m/min, 40-60min/day) 혹은 EE에 노출시켰다. 그 결과 AlCl₃ 투여에 의한 인지기능 저하와 근 기능 감소가 TE와 EE에 의해 완화된 것으로 나타났다. 또한, TE와 EE는 AD 질환에서 나타나는 β-amyloid(Aβ), alpha-synuclein 및 tumor necrosis factor-α(TNF-α) 단백질의 발현 증가를 감소시킨 것으로 나타났다. 게다가 TE와 EE는 AlCl₃ 투여에 의해 감소된 밀착연접 단백질(Occludin, Claudin-5 및 ZO-1)의 발현을 통계적으로 유의하게 증가시킨 것으로 나타났다. 마지막으로 Aβ 단백질과 밀착연접 단백질과의 상관분석을 실시한 결과 부적 상관관계(Occludin: r=-0.853, p=0.001; Claudin-5 : r=-0.352, p=0.915; ZO-1 : r=-0.424, p=0.0390)로 나타났다. 따라서 이를 종합해 보면 TE 혹은 EE 처치는 AD에 나타나는 병리학적 특징들을 일부 완화시켜 인지기능과 근 기능을 일부 개선 시킬 수 있는 효과적인 운동 방법이라고 생각된다.

• 한국산학기술학회논문지
• /
• 제12권9호
• /
• pp.3834-3842
• /
• 2011

본 연구에서는 선천적으로 관절 느슨함과 낮은 근 장력을 갖고 있는 다운증후군아동 보행의 운동학적 특성을 알아보고자 한다. 특히 자료수집의 편리성과 재현성이 높고, 유용한 보행훈련도구로서 그 사용이 증가되는 추세인 트레드밀에서 보행을 실시하였다. 다른 중복장애가 없는 다운증후군 남자아동 10명을 대상으로 적외선카메라로 3차원 보행 자료를 수집하여 시공간적 변인과 운동학적 변인을 산출하여 이들의 보행특성을 분석하였다. 그 결과, 다운증후군아동들은 선천적인 근골격계 특성으로 인한 보행불안정성을 극복하기 위해 엉덩, 무릎, 발목관절 모두를 구부리고 걷는 구부정 걸음(crouch gait)형태를 보였으며, 모든 다리관절의 신전을 작게 하여 결과적으로 추진력이 자제하였다. 이는 더 크게 신체를 추진할수록 발뒤꿈치 착지 시에 체중수용의 부담이 증가하기 때문인 것으로 판단된다. 이 연구 결과는 다운증후군의 관절불안정성을 개선하기 위해 효과적인 근 골격계 강화훈련 프로그램을 마련하는데 유용한 자료를 제공할 것으로 기대되며, 다운증후군뿐만 아니라 선천적 또는 후천적 근골격계 장애를 개선하거나 극복할 수 있는 운동프로그램 개발에도 참고 자료가 될 것으로 예상된다.

• 대한통합의학회지
• /
• 제11권2호
• /
• pp.69-76
• /
• 2023

Purpose : This study aimed to compare lung capacity measures (forced vital capacity; FVC, forced expiratory volume at 1 second; FEV1, and FEV1/FVC) and the activities of rectus femoris (RF) and gastrocnemius (GCM) muscles between young adults prescribed aerobic exercise combined with lower limb strength exercise (complex exercise) and those prescribed only aerobic exercise. Methods : We randomly divided 22 young adults into 2 groups: the complex exercise group that combined the leg strengthening and aerobic exercises (n = 11) and the aerobic-exercise-only group (n=11). Before the intervention, the FVC, FEV1, and FEV1/FVC values and the activities of RF and GCM muscles were measured. Measurements were in triplicates, and the average of the 3 measurements was used. The complex exercise group performed the treadmill exercise followed by squats and lunges, and the group performed only the treadmill exercise. Both groups were allocated the same time. Both groups performed the assigned exercise thrice a week for 3 weeks. After the intervention, the FVC, FEV1, and FEV1/FVC values and the activities of RF and GCM muscles were measured again. Results : The FVC and FEV1 values increased significantly in both groups after the intervention (p<.05). RF activity increased significantly after the intervention in the complex exercise group (p<.05), and the magnitude of change in RF activity after the intervention was significantly higher in the complex exercise group than in the aerobic-exercise-only group (p<.05). GCM activity also significantly increased after the intervention in both groups (p<.05). Conclusion : On the basis of our results, we recommend combining leg strengthening and aerobic exercise to improve leg muscle activity along with lung function.

• Physical Therapy Rehabilitation Science
• /
• 제4권1호
• /
• pp.17-21
• /
• 2015

Objective: In this study, we aimed to test the hypothesis that aerobic exercise might exert its cardio-protective effect by preventing oxidative stress and improving cardiac function in rat models with doxorubicin-induced cardiomyopathy. Design: Randomized controlled trial. Methods: We randomly divided experimental rats into four groups: the normal group was used as a non-cardiomyopathy normal control (n=10); the control group included non-aerobic exercise after doxorubicin-induced cardiomyopathy (n=10); the experimental group I included aerobic exercise (3 m/min) after doxorubicin-induced cardiomyopathy (n=10); and experimental group II included aerobic exercise (8 m/min) after doxorubicin-induced cardiomyopathy. Rats in the treadmill training groups underwent treadmill training, which began at 2 weeks after the first intraperitoneal injection. At the end of the exercise period, we determined the heart weight change for each rat. Changes in the levels of oxidative stress enzymes (superoxide dismutase [SOD], thiobarbituric acid-reactive substances [TBARS], and catalase) in the cardiac tissue of rats from all four groups were examined at the end of the experiment. Results: Significant cardiac myocyte injury and increase in myocardial TBARS concomitant with a reduction in myocardial SOD and catalase were observed following cardiomyopathy (p<0.05). Significant cardiac tissue and increase in myocardial TBARS along with reduction in myocardial SOD and catalase were observed following cardiomyopathy (p<0.05). Oxidative parameters were significantly improved in the aerobic exercise groups compared with the control group. Conclusions: These findings indicate that aerobic exercise effectively prevents oxidative stress in rat models with cardiomyopathy.

• 생명과학회지
• /
• 제20권3호
• /
• pp.444-452
• /
• 2010

본 연구의 목적은 PS-2 (N141I) 알츠하이머 형질전환 모델 생쥐를 대상으로 트레드밀 운동이 뇌의 세포질과 미토콘드리아의 $A{\beta}$-42, cytochrome c, SOD-1, 2 and Sirt-3 단백질 발현에 미치는 효과를 알아보는데 있다. 우선 알츠하이머 형질전환 생쥐를 Non-Tg-sedentary (n=5), Non-Tg-treadmill exercise (n=5) 집단과 Tg-sedentary (n=5), Tg-treadmill exercise (n=5) 집단으로 구분하고 트레드밀 운동을 통한 신경보호 효과를 검증하기 위해 Tg와 Non-Tg집단에 12주간 트레드밀 운동을 수행한 후 인지능력을 살펴보고 뇌의 세포질과 미토콘드리아의 $A{\beta}$-42, cytochrome c, anti-oxidant enzymes (SOD-1, SOD-2)와 Sirt-3 단백질을 분석하였다. 먼저 트레드밀운동은 Tg 집단에서 인지능력의 개선을 나타냈으며 미토콘드리아의 $A{\beta}$-42와 세포질의 cytochrome c 단백질의 감소와 항산화 효소인 SOD-1, SOD-2를 유의하게 증가시켰다. 게다가 트레드밀 운동은 모든 집단에서 Sirt-3 단백질의 발현을 증가시켰다. 따라서 트레드밀 운동은 인지능력의 향상과 세포 내 스트레스를 유발하는 $A{\beta}$-42를 억제시켜 알츠하이머 질환을 개선시킬 수 있는 효과적인 방법이라고 생각된다.