• Title/Summary/Keyword: Transporter rCNT2

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Pharmacogenomic Application for Gene Targeting and Molecular Characterization of a Nucleoside Transporter hCNT2 in Human Intestine

  • Shin, Ho-Chul;Lee, Jong-Hwa;Lee, Han-Ok;Duxin Sun;Gordon L. Amidon
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.158-159
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    • 2003
  • We have cloned and functionally expressed a sodium dependent human nucleoside transporter, hCNT2, from a CNS cancer cell line U251. Our cDNA clone of hCNT2 had the same predicted amino acid sequence as the previously cloned hCNT2 transporter. Of the several cell lines studied, the best hCNT2 transport function was obtained when transiently expressed in U251 cells.(omitted)

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