• 한국지진공학회논문집
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• 제19권4호
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• pp.161-171
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• 2015

A series of tests was conducted for full-scale single-pylon asymmetric cable-stayed bridges using a system of multiple shaking tables. The 2-span bridge length was 28 m, and the pylon height was 10.2 m. 4 different base conditions were considered: the fixed condition, RB (rubber bearings), LRB (lead rubber bearings), and HDRB (high damping rubber bearings). Based on investigation of the seismic response, the accelerations and displacements in the axial direction of the isolated bridge were increased compared to non-isolated case. However, the strain of the pylon was decreased, because the major mode of the structure was changed to translation for the axial direction due to the dynamic mass. The response of the cable bridge could differ from the desired response according to the locations and characteristics of the seismic isolator. Therefore, caution is required in the design and prediction in regard to the location and behavior of the seismic isolator.

• 한국컴퓨터정보학회지
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• 제2권1호
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• pp.45-54
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• 1995

본 연구는 ASCII 코드중에서 잘 쓰이지 않는 코드를 반달점(ˇ)으로 할당, 글꼴을 제작하여, 사용자가 국어 로마자 표기법 기본원칙을 모르더라도 한글단어, 문장, 문서를 문자열(string)로 입력받아 알고리즘화된 음운법칙을 적용하여 소리글자로 자동 변환 후 현행 정부 표준안인 국어 로마자 표기법 테이블에서 대응 글자를 참조하여 기계화 코드 변환이 가능토록 설계하였으며, 예외어 처리, 화면색상 및 풀다운 팝업 메뉴 방식을 지원, 마우스 활용 방식을 채택, 사용자 편리성을 제공하였으며, 다양한 서체, 글꼴 확대 및 축소, 이단ㆍ혼합 인쇄기능 등을 고려 C언어를 이용하여 구현하였다.

• 한국콘텐츠학회논문지
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• 제19권2호
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• pp.469-476
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• 2019

로봇의 움직임은 3차원 공간상의 다관절 좌표계의 회전 및 이송으로 표현된다. 이러한 좌표계 모델링을 위해 동차 변환 행렬의 관계식으로 표현하나 복잡한 3차원 공간상의 움직임을 고려하여 시각화 기법을 이용한 시뮬레이션 환경 기반의 모델링 및 생성한 동작의 확인이 필수적이다. 기존 시뮬레이션 환경의 경우, 플랫폼 의존도가 높으면 정해진 명령어의 수행으로 구성되어 사용성 및 확장의 한계성이 있었다. 본 논문에서는, 웹 기반의 3차원 시뮬레이션 환경을 구축하고, 소형 웹 서버 모듈과 사용성이 용이한 Python 스크립트의 연동 방식을 통해 높은 사용자 접근성을 얻고자 한다. 또한 로봇 제어를 위한 비선형 모델의 적용 사례를 통해 제안된 시스템의 연산 능력, 프로세스 관리 방식의 성능 및 사용자 스크립트 연동을 통한 확장성을 검증하고자 한다.

• Journal of Microbiology and Biotechnology
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• 제30권2호
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• pp.187-195
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• 2020

To understand the molecular mechanism involved in the survivability of cold-tolerant lactic acid bacteria was of great significance in food processing, since these bacteria play a key role in a variety of low-temperature fermented foods. In this study, the cold-stress response of probiotic Lactobacillus plantarum K25 isolated from Tibetan kefir grains was analyzed by iTRAQ proteomic method. By comparing differentially expressed (DE) protein profiles of the strain incubated at 10℃ and 37℃, 506 DE proteins were identified. The DE proteins involved in carbohydrate, amino acid and fatty acid biosynthesis and metabolism were significantly down-regulated, leading to a specific energy conservation survival mode. The DE proteins related to DNA repair, transcription and translation were up-regulated, implicating change of gene expression and more protein biosynthesis needed in response to cold stress. In addition, two-component system, quorum sensing and ABC (ATP-binding cassette) transporters also participated in cell cold-adaptation process. These findings provide novel insight into the cold-resistance mechanism in L. plantarum with potential application in low temperature fermented or preserved foods.

• Investigative Magnetic Resonance Imaging
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• 제21권4호
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• pp.223-232
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• 2017

Purpose: To report the use of multiband accelerated echo-planar imaging (EPI) for resting-state functional MRI (rs-fMRI) to achieve rapid high temporal resolution at 3T compared to conventional EPI. Materials and Methods: rs-fMRI data were acquired from 20 healthy right-handed volunteers by using three methods: conventional single-band gradient-echo EPI acquisition (Data 1), multiband gradient-echo EPI acquisition with 240 volumes (Data 2) and 480 volumes (Data 3). Temporal signal-to-noise ratio (tSNR) maps were obtained by dividing the mean of the time course of each voxel by its temporal standard deviation. The resting-state sensorimotor network (SMN) and default mode network (DMN) were estimated using independent component analysis (ICA) and a seed-based method. One-way analysis of variance (ANOVA) was performed between the tSNR map, SMN, and DMN from the three data sets for between-group analysis. P < 0.05 with a family-wise error (FWE) correction for multiple comparisons was considered statistically significant. Results: One-way ANOVA and post-hoc two-sample t-tests showed that the tSNR was higher in Data 1 than Data 2 and 3 in white matter structures such as the striatum and medial and superior longitudinal fasciculus. One-way ANOVA revealed no differences in SMN or DMN across the three data sets. Conclusion: Within the adapted metrics estimated under specific imaging conditions employed in this study, multiband accelerated EPI, which substantially reduced scan times, provides the same quality image of functional connectivity as rs-fMRI by using conventional EPI at 3T. Under employed imaging conditions, this technique shows strong potential for clinical acceptance and translation of rs-fMRI protocols with potential advantages in spatial and/or temporal resolution. However, further study is warranted to evaluate whether the current findings can be generalized in diverse settings.

• Spatial Information Research
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• 제7권2호
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• pp.255-269
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• 1999

본 연구에서는 우리나라의 수치지형도를 객체지향적 설계 분석 방법을 통해 객체화하기위한 실험적 연구이다. 객체지향 개발에서 가장 중요한 고려요소인 캡슐화, 다형성, 상속등을 통해 가능한 정보은폐된 수치지형도 객체를 설계하였다. 이를 이해 수치지형도의 자료모형을 분석하고, 지도 사상들 간의 상호관계를 계층적으로 파악하였다. 이로부터 현재 수치지형도의 레이어 구성은 공간자료모형이나 자료 정의의 측면에서 개념적으로 정의한 계층이 실제 자료 특성에 모호하게 반영되어 이를 구체화하기 어려운 구조를 갖고 있음을 밝혔다. 이러한 한계 때문에 '자료 레이어' 단계와 '객체 클래스' 단계를 통합하여 객체의 계층을 구분하였고, 수치지형도 공간 원형 클래스를 정의하여 이를 통해 공간 객체를 자신의 자원으로 활용하는 연계 매커니즘(ISCO)을 통하여 수치지형도 레이어 객체들을 설계하였다. 그리고 설계한 수치지형도 객체를 JAVA를 통해 구현한 다음 실제 웹 인터페이스를 통해 인터넷 환경에서 편리하게 상호 공유하여 수치지형도 객체의 효율성을 검증하였다.

• Interdisciplinary Bio Central
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• 제1권1호
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• pp.3.1-3.6
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• 2009

Introduction: GTPases known as translation factor play a vital role as ribosomal subunit assembly chaperone. The bacterial Obg proteins ($Spo{\underline{0B}}$-associated ${\underline{G}}TP$-binding protein) belong to the subfamily of P-loop GTPase proteins and now it is considered as one of the new target for antibacterial drug. The majority of bacterial Obgs have been commonly found to be associated with ribosome, implying that these proteins may play a fundamental role in ribosome assembly or maturation. In addition, one of the experimental evidences suggested that Bacillus subtilis Obg (BsObg) protein binds to the L13 ribosomal protein (BsL13) which is known to be one of the early assembly proteins of the 50S ribosomal subunit in Escherichia coli. In order to investigate binding mode between the BsObg and the BsL13, protein-protein docking simulation was carried out after generating 3D structure of the BsL13 structure using homology modeling method. Materials and Methods: Homology model structure of BsL13 was generated using the EcL13 crystal structure as a template. Protein-protein docking of BsObg protein with ribosomal protein BsL13 was performed by DOT, a macro-molecular docking software, in order to predict a reasonable binding mode. The solvated energy minimization calculation of the docked conformation was carried out to refine the structure. Results and Discussion: The possible binding conformation of BsL13 along with activated Obg fold in BsObg was predicted by computational docking study. The final structure is obtained from the solvated energy minimization. From the analysis, three important H-bond interactions between the Obg fold and the L13 were detected: Obg:Tyr27-L13:Glu32, Obg:Asn76-L13:Glu139, and Obg:Ala136-L13:Glu142. The interaction between the BsObg and BsL13 structures were also analyzed by electrostatic potential calculations to examine the interface surfaces. From the results, the key residues for hydrogen bonding and hydrophobic interaction between the two proteins were predicted. Conclusion and Prospects: In this study, we have focused on the binding mode of the BsObg protein with the ribosomal BsL13 protein. The interaction between the activated Obg and target protein was investigated with protein-protein docking calculations. The binding pattern can be further used as a base for structure-based drug design to find a novel antibacterial drug.

• 한국정보처리학회논문지
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• 제3권2호
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• pp.295-304
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• 1996

여러가지 미디어를 통합하여 처리가 가능한 광대역 ISDN의 서비스 전개를 경제적 으로 실현하기 위해서는 지상망과 위성망을 조합한 시스템을 구축하는 것이 필요하다. 이러한 위성을 이용한 전송방식으로서는 다양한 지역에 산재한 사용자를 효율적으로 수용 가능한 TDMA 방식이 활용되고 있다. 그러나 동기 방식인 위성 TDMA회선과 비동기 전송 모드인 ATM을 이용하는 지상망의 접속에 있어서는 셀 지연 변이로 대표되는 ATM 전송품질의 열화가 큰 문제로 된다. 따라서 비동기 전송에 대응 가능한 지연 변이의 보상 방식이 필요하게 된다. 이 ATM과 TDMA 간의 변환에서는 지연 변이의 초대 효율을 요구값 이하로 억제하고 전송 셀의 버스트 특성이 증가하지 않는 조건으로 위성회선을 효율적으로 이용하는 방법 등이 연구되고 있다. 본 논문에서는 우선 지상망에서 검토되 殷있는 타임 스탬프(time stamp)방식을 지연변이 보상 방법으로 위성회선에 이용한 경우의 문제점을 해석하였다.그리고이를 해결하기 위한 이산 셀 계수 방법을제안하여 셀전송 타이밍 정보의 전송용량과 오류율을 해석하였다. 또한 셀 전송타이밍 정보에 부호 오류가 일어난 경우에도 시스템은 안정되게 동작하고 신뢰성이 검증되어 제안된 보상 방법이 우수함을 알 수 있다.

• International Journal of Computer Science & Network Security
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• 제22권7호
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• pp.213-219
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• 2022

Building Ukraine as an independent, sovereign state requires the education of a citizen-patriot, able to live and work in a democracy, ensure the unity of Ukraine, feel constant responsibility for themselves, their people, country, seek to make a real contribution to the reform process. Modern modernization of the education system requires the search for new information and communication technologies that can ensure the formation of a citizen with an active civic position, which involves not only students mastering the rights and responsibilities of citizens, convincing them of the feasibility of democratic transformation of society, patriotic qualities and feelings, but also the identification of motivated civic actions. The pandemic and hostilities have led to significant changes in the field of education around the world, they have caused educational problems in Ukraine. At the beginning of the quarantine in the spring of 2020, all educational institutions in the emergency mode switched to distance learning. Intensive use of information and communication technologies in the life of modern society has led to a rethinking of the content of education and training of future professionals: the main role is played not so much by the information itself as the ability to work with it, critically comprehend and produce new knowledge; the main thing is not the amount of information, but its quality; information is needed for further practical application and transformation into knowledge, and the ability to work with information becomes one of the important competencies of the modern specialist in the new transformation of society: from information to the knowledge society. In this context, one of the main forms of training is distance learning, which is able to respond to the challenges of society. The main methodological positions that are taken into account in the construction of the structure and dynamics of the formation of civic responsibility of the individual during the use of information and communication technologies are highlighted. The structure of civil responsibility as a holistic system of information and communication technologies is outlined, which includes three subsystems that characterize the natural, social and systemic qualities of citizenship, interconnected hierarchically and synergistically.The constituent elements of the structural part of the model of civic culture of the individual are analyzed.