• 한국항해항만학회지
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• 제39권4호
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• pp.285-291
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• 2015

해상 사고에 의한 익수자는 저체온증에 의한 사망 위험에 노출되어 있다. 구명 동의 등을 착용함으로써 부력은 유지할 수 있으나 해수의 낮은 온도에 의한 신체의 열손실은 짧은 시간 내에 체온을 하강시키고 그에 따른 저체온증 사망이 우려된다. 전통적인 구명 동의는 고체형 부력체를 사용하여 부력을 향상 시키고 있으나, 구명 동의에 공기를 채움으로써 부력 및 체온 보존 효과를 얻을 수 있을 것으로 판단된다. 본 연구는 고체형 충진재를 이용한 기존의 비 팽창형 구명 동의와 공기를 채운 팽창형 구명 동의의 단열 성능을 비교하고, 각각의 방법이 체온 변화에 미치는 영향을 정성적으로 평가하고자 한다. 먼저 열저항 모델을 이용한 대략적인 단열 성능의 비교를 실시하고, 유한요소법을 이용하여 Pennes의 신체 열전달 해석을 수행하여 시간에 따른 체온 변화를 수치적으로 검토하였다.

• 한국안전학회지
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• 제11권4호
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• pp.143-150
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• 1996

본 연구는 선형, 비선형 hygrothermal 응력 문제를 위한 explicit-Implicit 유한요소 해석 모델 개발에 관한 것이다. 부가적으로 moilsture 확산 방정식, J-적분 평가를 위한 균열 요소 및 가상 균열 진전법이 도입된다. 시간 변화에 따른 균열 추진력을 계산하기 위하여 선형 탄성 파괴 역학(LEFM)이론이 고려되며 재료의 기공은 실온에서 액체 상태의 습기로 포화되어 있으며 온도가 상승함에 따라 증기화된다는 가정하에서 균열 추진력과 증기 효과의 관계가 연구된다. 이상 기체방정식은 각 시간 단계에서 증기에 의한 열역학적 압력을 계산하기 위하여 이용된다. 다공질 재료의 시간 종속 응답을 지배하는 방정식들은 혼합이론에 기초하며 다공질 재료의 유체 흐름을 위한 Darcy의 법칙과 Von-Mises 항복 기준을 포함하고 있는 Perzyna의 점소성 모델이 첨가된다. 또한 Green-Naghdi 응력률이 중첩된 강체 운동하에서 응력 텐서 invariant로 사용되며, 모델링을 위하여 사각요소가 이용되고 비선형 지배 방정식을 풀기 위하여 full Newton-Raphson법에 의한 반복법이 사용된다. 본 연구를 통하여 얻은 결과는 다음과 같다. 1) 본 유한요소 프로그램은 복합재의 hygrothermal 파괴 해석에 매우 유용하게 적용될 수 있다. 2) 습기의 온도에 의한 영향을 가지는 재료의 J-적분을 정확히 예측하기 위하여는 증기 효과를 고려하여야 한다. 왜냐하면 초기단계에 균열 전파력이 가속되기 때문이다. 3) 본 해석을 위해 Uncoupled scheme에 의한 결과도 Coupled scheme에 결과에 비해 아주 타당하므로 CPU 측면에서 매우 경제적인 Uncoupled scheme이 추천된다.

• 터널과지하공간
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• 제23권3호
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• pp.241-259
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• 2013

충전층을 이용한 열에너지저장 시스템은 자갈이나 콘크리트와 같은 열저장매질과 공기나 오일과 같은 열전달유체를 이용하여 현열에너지를 저장하는 방식으로서, 저장매질의 경제성과 화학적 안정성, 시스템 구축의 용이성 등 많은 장점이 갖는다. 본 연구에서는 충전층을 이용한 열에너지저장 기술에 대하여 개략적으로 소개하고, 이러한 열에너지저장소의 에너지 수지와 성능 효율을 분석하기 위한 수치 모델을 제시하였다. 유한차분법을 이용하여 저장소 내 1차원 비정상 열전달 해석을 수행하였으며, 반복적인 주입과 토출에 따른 충전층의 온도분포와 외부로의 손실 에너지를 계산하였다. 해석모델은 AA-CAES(advanced adiabatic compressed air energy storage)와 연계된 고온의 열에너지저장시스템으로 저장소가 지하암반 내에 위치하는 경우와 지상에 위치하는 경우를 모사하고, 성능효율 및 열손실률을 비교 분석하였다.

• 한국항행학회논문지
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• 제7권1호
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• pp.38-50
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• 2003

본 논문에서는 도선상에서 발생하는 결함 위치와 이상 유무를 감지하는 새로운 고분해능 반사측정법인 시간-주파수 영역반사측정법 (TFDR, Time-Frequency Domain Reflectometry)을 제안하였다. 고전적인 반사측정법들은 단지 시간 또는 주파수의 한 영역에서 분석되어져 왔으나, 본 논문에서 제시한 TFDR은 도선의 결함 위치와 이상 유무를 발견하기 위해 과도신호의 시간과 주파수 영역의 정보를 동시에 이용할 수 있는 시간-주파수 분석기법으로 특성화하였다. TFDR의 기준신호 설계는 측정 케이블의 물리적 성질들을 고려하여 주파수 밴드를 결정하며, 도선의 결함감지와 추정은 시간-주파수 상호상관관계 함수에 의해 이루어진다. TFDR 시스템을 이용하여 여러 결함 상태를 가진 실제 coaxial cable (RG-142, RG-400)에 대해 실험하였고 정확성을 입증하기 위해 TDR (Time Domain Reflectometry) 장비와 성능을 비교하였다. 본 논문에서는 TFDR이 TDR보다 작은 오차로 결함을 찾아냄을 나타내고 있으며, 측정된 정확도는 TFDR의 오차율이 0.5% 이하로 TDR (54750A/54754A) 장비보다 성능이 월등히 우수하다는 것을 알 수 있다.

• 한국정보통신학회논문지
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• 제12권5호
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• pp.879-886
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• 2008

본 논문에서는 저전압 차동 신호(Low-Voltage Differential Signaling, LVDS) 전송방식의 응용을 위한 차동 전송 접속 경로의 분석 및 설계 최적화 방법을 제안한다. 차동 전송 경로 및 저전압 스윙 방법의 발전으로 인해 LVDS 방식은 데이터 통신 분야, 고해상도 디스플레이 분야, 평판 디스플레이 분야에서 매우 적은 소비전력, 개선된 잡음 특성 및 고속 데이터 전송률을 제공한다. 본 논문은 차동 유연성 인쇄회로 보드(flexible printed circuit board, FPCB) 전송선에서 선폭, 선두께 및 선 간격과 같은 전송선 설계 변수들의 최적화 기법을 이용하여 직렬 접속된 전송선에서 발생하는 임피던스 부정합과 신호왜곡을 감소시키기 위해 개선 모델과 새로이 개발된 수식을 제안한다. 이러한 차동 FPCB 전송선의 고주파 특성을 평가하기 위해 주파수 영역에서 전파(full-wave) 전자기 시뮬레이션, 시간영역 시뮬레이션 및 S 파라미터 시뮬레이션을 각각 수행하였다. $17.5{\mu}m$과 $35{\mu}m$의 전송선의 경우, 전극 폭에서의 약 10% 변화가 차동 임피던스에서의 약 6%와 5.6%의 변화를 각각 보였으나, 전송선 간 간격은 차동 및 특성 임피던스에서의 영향을 주지 않음을 확인하였다. 또한 전송선 간격이 증가할수록 상호 인덕턴스 및 커패시턴스가 감소하기 때문에 누화 잡음을 감소시키기 위해 신호 전송선간의 간격을 $180{\mu}m$ 이상 유지 해야함을 확인하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제23권2호
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• pp.151-159
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• 2019

Pruritus (itching) is classically defined as an unpleasant cutaneous sensation that leads to scratching behavior. Although the scientific criteria of classification for pruritic diseases are not clear, it can be divided as acute or chronic by duration of symptoms. In this study, we investigated whether skin injury caused by chemical (contact hypersensitivity, CHS) or physical (skin-scratching stimulation, SSS) stimuli causes initial pruritus and analyzed gene expression profiles systemically to determine how changes in skin gene expression in the affected area are related to itching. In both CHS and SSS, we ranked the Gene Ontology Biological Process terms that are generally associated with changes. The factors associated with upregulation were keratinization, inflammatory response and neutrophil chemotaxis. The Kyoto Encyclopedia of Genes and Genomes pathway shows the difference of immune system, cell growth and death, signaling molecules and interactions, and signal transduction pathways. Il1a, Il1b and Il22 were upregulated in the CHS, and Tnf, Tnfrsf1b, Il1b, Il1r1 and Il6 were upregulated in the SSS. Trpc1 channel genes were observed in representative itching-related candidate genes. By comparing and analyzing RNA-sequencing data obtained from the skin tissue of each animal model in these characteristic stages, it is possible to find useful diagnostic markers for the treatment of itching, to diagnose itching causes and to apply customized treatment.

• 대한간학회지
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• 제24권4호
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• pp.384-391
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• 2018

Backgrounds/Aims: The objective of our study was to determine the epidemiological, laboratory, and serological characteristics of patients with chronic hepatitis B virus (HBV) infection and normal transaminases. The study also aimed to evaluate liver damage by measuring the liver fibrosis (LF) grade and to identify possible factors associated with the presence of fibrosis. Methods: A retrospective observational study was conducted in patients with chronic HBV infection and classified as inactive carriers or immune-tolerant. Epidemiological variables of age, sex, immigrant, alcohol consumption, and body mass index (BMI), as well as virological variables (HBV DNA) and transaminase level were collected throughout the follow-up. The LF grade was evaluated by transient elastography. The cutoff value for significant fibrosis (SF) was liver stiffness ${\geq}7.9kPa$. Results: A total of 214 patients were included in the analysis, and 62% of them had a BMI ${\geq}25kg/m^2$. During follow-up, 4% of patients showed transaminase elevation (<1.5 times normal). Most patients had a viral DNA level <2,000 IU/mL (83%). Data on LF were available in 160 patients; of these, 14% had SF, 9% F3, and 6% F4. The variables associated with the presence of SF were transaminase alteration during follow-up, as 23% of patients with SF had elevated transaminases versus 3% of patients without SF (P<0.005), and BMI, as the vast majority of patients with SF (88%) had a BMI ${\geq}25kg/m^2$ versus 56% of patients without SF (P<0.05). Conclusions: In patients with chronic HBV infection and normal transaminases, liver damage does not seem to be related to DNA levels, alcohol consumption, or immigrant status. SF seems to be associated with transaminase alteration during follow-up and elevated BMI. It is therefore recommended to measure LF grade with validated non-invasive methods in such patients.

• Journal of Korean Neurosurgical Society
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• 제65권6호
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• pp.801-815
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• 2022

Objective : To evaluate the stent apposition of a low-profile visualized intraluminal support (LVIS) device in distal internal carotid artery (ICA) aneurysms, examine its correlation with clinical and angiographic outcomes, and determine the predictive factors of ischemic adverse events (IAEs) related to stent-assisted coiling. Methods : We retrospectively analyzed a prospectively maintained database of 183 patients between January 2017 and February 2020. The carotid siphon from the cavernous ICA to the ICA terminus was divided into posterior, anterior, and superior bends. The anterior bends were categorized into angled (V) and non-angled (C, U, and S) types depending on the morphology and measured angles. Complete stent apposition (CSA) and incomplete stent apposition (ISA) were evaluated using unsubtracted angiography and flat-panel detector computed tomography. Dual antiplatelet therapy with aspirin 200 mg and clopidogrel 75 mg was administered. Clopidogrel resistance was defined as fewer responders (≥10%, <40%) and non-responders (<10%) based on the percent inhibition (%INH) of the VerifyNow system. These were counteracted by a dose escalation to 150 mg for fewer responders or substitution with cilostazol 200 mg for non-responders. IAEs included intraoperative in-stent thrombosis, transient ischemic attack, cerebral infarction, and delayed in-stent stenosis. A multivariate logistic regression analysis was used to determine the predictive factors for ISA and IAEs. Results : There were 33 ISAs (18.0%) and 27 IAEs (14.8%). The anterior bend angle was narrower in ISA (-4.16°±25.18°) than in CSA (23.52°±23.13°) (p<0.001). The V- and S-types were independently correlated with the ISA (p<0.001). However, treatment outcomes, including IAEs (15.3% vs. 12.1%), aneurysmal complete occlusion (91.3% vs. 88.6%), and recanalization (none of them), did not differ between CSA and ISA (p>0.05). The %INH of 27 IAEs (13.78%±14.78%) was significantly lower than that of 156 non-IAEs (26.82%±20.23%) (p<0.001). Non-responders to clopidogrel were the only significant predictive factor for IAEs (p=0.001). Conclusion : The angled and tortuous anatomical peculiarity of the carotid siphon caused ISA of the LVIS device; however, it did not affect clinical and angiographic outcomes, while the non-responders to clopidogrel affected the IAEs related to stent-assisted coiling.

• Geomechanics and Engineering
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• 제32권1호
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• pp.111-123
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• 2023

The slope of an open cut tunnel is located above the exit of the Leijia tunnel on the Changgan high-speed railway. During the excavation of the open cut tunnel foundation pit, the slope slipped twice, a large landslide of 92500 m³ formed. The landslide body and unstable slope body not only caused the foundation pit of the open cut tunnel to be buried and the anchor piles to be damaged but also directly threatened the operational safety of the later high-speed railway. Therefore, to study the stability change in the slope of the open cut tunnel under heavy rain and excavation conditions, a 3D numerical calculation model of the slope is carried out by Midas GTS software, the deformation mechanism is analyzed, anti-sliding measures are proposed, and the effectiveness of the anti-sliding measures is analyzed according to the field monitoring results. The results show that when rainfall occurs, rainwater collects in the open cut tunnel area, resulting in a transient saturation zone on the slope on the right side of the open cut tunnel, which reduces the shear strength of the slope soil; the excavation at the slope toe reduces the anti-sliding capacity of the slope toe. Under the combined action of excavation and rainfall, when the soil above the top of the anchor pile is excavated, two potential sliding surfaces are bounded by the top of the excavation area, and the shear outlet is located at the top of the anchor pile. After the excavation of the open cut tunnel, the potential sliding surface is mainly concentrated at the lower part of the downhill area, and the shear outlet moves down to the bottom of the open cut tunnel. Based on the deformation characteristics and the failure mechanism of the landslides, comprehensive control measures, including interim emergency mitigation measures and long-term mitigation measures, are proposed. The field monitoring results further verify the accuracy of the anti-sliding mechanism analysis and the effectiveness of anti-sliding measures.

• Nuclear Engineering and Technology
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• 제54권11호
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• pp.4348-4358
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• 2022

The thermal-hydraulics phenomena in a containment during an accident will necessarily include radiative heat transfer (i) within the gas mixture due to the high radiative absorption and emission of steam and (ii) between the gas mixture and the surrounding structures. The analysis of some previous PANDA experiments (PSI, Switzerland) demonstrated the importance of the proper modelling of radiation for the benefit of numerical simulations. These results together with dedicated scoping calculations conducted for the present experiments indicated that the radiative heat transfer is considerable, even for a very low amount of steam (≈2%). The H2P2 series conducted in the large-scale PANDA facility at the Paul-Scherrer-Institut (PSI) in the framework of the OECD/NEA HYMERES-2 project is intended to enhance the understanding of thermal radiation phenomena and to provide a benchmark for corresponding numerical simulations. Thus, the test matrix was tailored around the two opposite extremes: either gas compositions with small steam content such that radiative heat transfer phenomena can be neglected. Or gas mixtures containing larger amounts of steam, so that radiative heat transfer is expected to play a dominant role. The H2P2 series consists of 5 experiments designed to isolate the radiation phenomena from convective and diffusive effects as much as possible. One vessel with a diameter of 4 m and a height of 8 m was preconditioned with different mixtures of air / steam at room and elevated temperatures. This was followed by the build-up of a stable helium stratification at constant pressure in the upper part of the vessel. After that, helium was injected from the top into the vessel which leads to an increase of the vessel pressure and a corresponding elevation-dependent and transient rise of the gas temperature. It is shown that even the addition of small amounts of steam in the initial gas atmosphere considerably impacts the radiative heat transport throughout all phases of the experiments and markedly influences i) the monitored gas peak temperature, ii) the temperature history during the compression and iii) the following relaxation phase after the compression was stopped. These PANDA experiments are the first of its kind conducted in a large scale thermal-hydraulic facility.